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myoblastom

A granular cell tumor that is confined to the site of origin, without metastatic potential.
NCI

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Caucasoid Race

Denotes a person with European, Middle Eastern, or North African ancestral origin who identifies, or is identified, as White. Reference: FDA Guidance on Race & Ethnicity ( http://www.fda.gov/cder/guidance/5656fnl.htm )
NCI

A person having origins in any of the original peoples of Europe, the Middle East, or North Africa.
NCI

Denotes person with European, Middle Eastern, or North African ancestral origin who identifies, or is identified, as White.
NCI

A group distinguished by classification according to physical features. This group, also called Europoid, centers around the Mediterranean Sea but includes other parts of Europe. (from Winick: Dictionary of Anthropology, 1972; American Heritage Dictionary, 2d College ed)
MSH

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sukcinátdehydrogenasa

A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.
MSH

creates a double bond between the 2 middle carbons of succinate to form fumarate.
CSP

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HIV

Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
MSH

species of Lentivirus, subgenus primate lentiviruses, formerly designated T cell lymphotropic virus type III/lymphadenopathy associated virus (HTLV-III/LAV); it is acknowledged to be the agent responsible for the acute infectious manifestations, neurologic disorders, and immunologic abnormalities linked to the Acquired Immunodeficiency Syndrome (AIDS).
CSP

The cause of acquired immunodeficiency syndrome (AIDS).
NCI

A cytopathic retrovirus. It is the etiological agent of AIDS.
NCI

The virus isolated and recognized as the etiologic agent of AIDS. HIV-1 is classified as a lentivirus, a subtype of retroviruses.
NCI

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fotofosforylace

The use of light to convert ADP to ATP without the concomitant reduction of dioxygen to water as occurs during OXIDATIVE PHOSPHORYLATION in MITOCHONDRIA.
MSH

Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation. [ISBN:0198547684]
GO

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myotonia congenita

Inherited myotonic disorders with early childhood onset MYOTONIA. Muscular hypertrophy is common and myotonia may impair ambulation and other movements. It is classified as Thomsen (autosomal dominant) or Becker (autosomal recessive) generalized myotonia mainly based on the inheritance pattern. Becker type is also clinically more severe. An autosomal dominant variant with milder symptoms and later onset is known as myotonia levior. Mutations in the voltage-dependent skeletal muscle chloride channel are associated with the disorders.
MSH

A genetic congenital neuromuscular disorder affecting the skeletal muscles. It is caused by mutations in the chloride channel gene (CLCN1 gene). It is characterized by muscle stiffness, hypertrophy, pain, and cramping.
NCI

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ceftazidim

Semisynthetic, broad-spectrum antibacterial derived from CEPHALORIDINE and used especially for Pseudomonas and other gram-negative infections in debilitated patients.
MSH

A beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. Ceftazidime binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Compared to the second and first generation cephalosporins, ceftazidime is more active against gram-negative bacteria and less active against gram-positive bacteria. Ceftazidine also crosses the blood-brain barrier and reaches therapeutic concentrations in the central nervous system (CNS).
NCI

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sulfamethoxazol

A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
MSH

sulfonamide bacteriostatic antibacterial agent.
CSP

A broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfamethoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.
NCI

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HLA-DR4 antigen

An HLA-DR antigen which is associated with HLA-DRB1 CHAINS encoded by DRB1*04 alleles.
MSH

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lékař a pacient – vztahy

The interactions between physician and patient.
MSH

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NADP

Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5`-phosphate (NMN) coupled by pyrophosphate linkage to the 5`-phosphate adenosine 2`,5`-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
MSH

nicotinamide adenine dinucleotide phosphate; a coenzyme composed of ribosylnicotinamide 5`-phosphate (NMN) coupled by pyrophosphate linkage to the 5`-phosphate adenosine 2`,5`-bisphosphate; serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced ( NADPH).
CSP

Nicotinamide Adenine Dinucleotide Phosphate, an oxidation-reduction coenzyme, found in eukaryotic cells and is involved in many enzymatic reactions.
NCI

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lokomoce buněk

ability of cells to move from one location to another.
CSP

Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg]
GO

Cell Motility consists of active translocation of a whole cell, or cell body, from one site to another; distinct from cell motion that involves movement of cell processes (e.g., axons, microvilli, etc.). (NCI)
NCI

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sulfoxidy

Organic compounds that have the general formula R-SO-R. They are obtained by oxidation of mercaptans (analogous to the ketones). (From Hackh`s Chemical Dictionary, 4th ed)
MSH

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homocystein

A thiol-containing amino acid formed by a demethylation of METHIONINE.
MSH

aminoacid with the side chain -CH2CH2SH, an intermediate in the biosynthesis of cysteine from methionine.
CSP

a kind of amino acid
CHV

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pikrylchlorid

A hapten that generates suppressor cells capable of down-regulating the efferent phase of trinitrophenol-specific contact hypersensitivity. (Arthritis Rheum 1991 Feb;34(2):180).
MSH

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naftaceny

Polyacenes with four ortho-fused benzene rings in a straight linear arrangement. This group is best known for the subclass called TETRACYCLINES.
MSH

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centrální nervový systém – látky depresorické

A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).
MSH

loosely defined group of drugs that tend to reduce the activity of the central nervous system.
CSP

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Manufactured Supplies

Goods for the support and maintenance of some endeavor.
NCI

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Ziekenhuisorganisatie en -bestuur

management of the internal organization of the hospital.
CSP

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kyselina piromidová

Antibacterial against mainly gram negative organisms. It is used for urinary tract and intestinal infections.
MSH

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Národní akademie věd (USA)

A United States organization of distinguished scientists and engineers established for the purpose of investigating and reporting upon any subject of art or science as requested by any department of government. The National Research Council organized by NAS serves as the principal operating agency to stimulate and support research.
MSH

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mozeček – kůra

The superficial gray matter of the cerebellum. It consists of two main layers, the stratum moleculare and the stratum granulosum. (Dorland, 28th ed)
MSH

superficial gray matter of the cerebellum; consists of two main layers, the stratum moleculare and the stratum granulosum.
CSP

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stomatochirurgické předprotetické výkony

Surgery necessary for a denture to rest on a firm base, free from marked osseous protuberances or undercuts, and devoid of interfering muscle attachments, excess mucoperiosteum, hyperplasias, and fibrous or papillary growths.
MSH

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nemocnice státní

Hospitals controlled by agencies and departments of the state government.
MSH

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placenta – funkční testy

Methods used for the assessment of placental function.
MSH

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necrobiosis lipoidica

A degenerative disease of the dermal connective tissue characterized by the development of erythematous papules or nodules in the pretibial area. The papules form plaques covered with telangiectatic vessels. More than half of the affected patients have diabetes.
MSH

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mozkomíšní mok – tlak

Manometric pressure of the CEREBROSPINAL FLUID as measured by lumbar, cerebroventricular, or cisternal puncture. Within the cranial cavity it is called INTRACRANIAL PRESSURE.
MSH

manometric pressure of the cerebrospinal fluid as measured by lumbar, cerebroventricular, or cisternal puncture.
CSP

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potní žlázy – nemoci

Diseases of the SWEAT GLANDS.
MSH

condition in which there is a deviation from or interruption of the normal structure or function of the sweat glands, which are sweat-producing structures that are embedded in the dermis.
CSP

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Human Genetics

The branch of genetics focusing on human heredity.
NCI

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plazma – objem

Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.
MSH

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