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theobromin

3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
MSH

3,7-dimethylxanthine, an alkaloid found in coca with properties similar to caffeine and theophylline.
CSP

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digitalisové glykosidy

Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.
MSH

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oční víčka – nemoci

pathologic condition of either of the two movable folds (upper and lower) that protect the anterior surface of the eyeball or eyelid.
CSP

Your eyelids help protect your eyes. When you blink, your eyelids spread moisture over your eyes. Blinking also helps move dirt or other particles off the surface of the eye. Closing your eyelids when something is coming towards your eyes can protect from injuries.

Like most other parts of your body, your eyelids can get infected, inflamed, or even develop cancer. There are also specific eyelid problems, including

  • Eyelids that turn in or out
  • Eyelids that droop
  • Abnormal blinking or twitching

Treatment of eyelid problems depends on the cause.


MEDLINEPLUS

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draslík – isotopy

Stable potassium atoms that have the same atomic number as the element potassium, but differ in atomic weight. K-41 is a stable potassium isotope.
MSH

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poruchy chování

any of various conditions characterized by impairment of an individual`s normal behavioral functioning, and caused by social, psychological, biochemical, genetic, or other factors, such as infection or head trauma.
CSP

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Klebsiella rhinoscleromatis

A species of facultatively anaerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is nonmotile and oxidase negative. K. rhinoscleromatis is pathogenic and the causative agent of rhinoscleroma, an upper respiratory disease of the nose and pharynx.
NCI

Any bacterial organism that can be assigned to the species Klebsiella rhinoscleromatis.
NCI

A gram-negative, facultatively anaerobic, rod-shaped bacterium found consistently and exclusively in patients with RHINOSCLEROMA and their contacts. Formerly an individual species, it is now considered a subspecies of K. pneumoniae.
MSH

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thiamintrifosfát

3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P`,P“-trioxide. The triphosphate ester of thiamine. In Leigh`s disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.
MSH

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dijodtyrosin

A product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (THYROXINE and TRIIODOTHYRONINE).
MSH

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faktor Xa

Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of prothrombin to thrombin in conjunction with other cofactors.
MSH

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prealbumin

A tetrameric protein, molecular weight between 50,000 and 70,000, consisting of 4 equal chains, and migrating on electrophoresis in 3 fractions more mobile than serum albumin. Its concentration ranges from 7 to 33 per cent in the serum, but levels decrease in liver disease.
MSH

Transthyretin (147 aa, ~16 kDa) is encoded by the human TTR gene. This protein is involved in both the binding and transport of retinol and thyroxine.
NCI

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benzaldehyde

A chemical used in flavorings and in some dyes, perfumes, and medicines. It is found in essential oils made from almonds and peach pits and in other foods. It can also be made in the laboratory.
NCI

A color liquid aldehyde with an almond odor. Benzaldehyde is found in many foods and is widely used in the chemical industry. In the chemical industry, this agent is used in the preparation of various aniline dyes, perfumes, flavorings, and pharmaceuticals. In addition, benzaldehyde has been associated with amygdalin (laetrile), since one of amygdalins breakdown products is benzaldehyde. (NCI)
NCI

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kyfóza

Deformities of the SPINE characterized by an exaggerated convexity of the vertebral column. The forward bending of the thoracic region usually is more than 40 degrees. This deformity sometimes is called round back or hunchback.
MSH

A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine.
NCI

Abnormally increased curvature of the thoracic portion of the spine.
NCI

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thioridazin

A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
MSH

phenothiazine compound having antipsychotic and sedative effects, used in treatment of schizophrenia and acute psychotic episodes, for relief of anxiety, agitiation and depression in mood disorders, and for treatment of disruptive behavior disorders in children.
CSP

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Dinoflagellida

Flagellate EUKARYOTES, found mainly in the oceans. They are characterized by the presence of transverse and longitudinal flagella which propel the organisms in a rotating manner through the water. Dinoflagellida were formerly members of the class Phytomastigophorea under the old five kingdom paradigm.
MSH

protozoans of the class Phytomastigophorea, found mainly in the oceans; they are characterized by the presence of transverse and longitudinal flagella which propel the organisms in a rotating manner through the water.
CSP

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Fanconiho syndrom

A hereditary or acquired form of generalized dysfunction of the PROXIMAL KIDNEY TUBULE without primary involvement of the KIDNEY GLOMERULUS. It is usually characterized by the tubular wasting of nutrients and salts (GLUCOSE; AMINO ACIDS; PHOSPHATES; and BICARBONATES) resulting in HYPOKALEMIA; ACIDOSIS; HYPERCALCIURIA; and PROTEINURIA.
MSH

constellation of clinical and laboratory manifestations produced by generalized proximal tubular insufficiency in the presence of normal, or nearly normal, glomerular filtration.
CSP

A genetic or acquired disorder characterized by impairment of the function of the proximal tubules of the kidney. It results in decreased reabsorption of electrolytes, glucose, amino acids, and other nutrients.
NCI

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těhotenství – trimestry

The three approximately equal periods of a normal human PREGNANCY. Each trimester is about three months or 13 to 14 weeks in duration depending on the designation of the first day of gestation.
MSH

A period of three months; especially one of the three three-month periods into which human pregnancy is divided.
NCI

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benzoylcholin

The benzoic acid ester of choline.
MSH

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laktamy

Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.
MSH

cyclic amides formed from aminocarboxylic acids by the elimination of water.
CSP

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trombastenie

A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).
MSH

platelet abnormality characterized by defective clot formation, impaired aggregation, and prolonged bleeding time; other manifestations include nosebleeds, inappropriate bruising, and excessive bleeding.
CSP

A rare, autosomal recessive inherited and less frequently acquired platelet disorder. It is characterized by deficient or dysfunctional glycoprotein IIb/IIIa complex. It leads to defective platelet aggregation, resulting in bleeding.
NCI

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dipyridamol

A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
MSH

platelet inhibitor and coronary vasodilator used to prevent thromboembolism associated with mechanical heart valves, as prophylactic adjunct in the prevention of myocardial reinfarction, and as a diagnostic aid adjunct in myocardial perfusion imaging; administered orally and intravenously.
CSP

A drug that prevents blood cell clumping and enhances the effectiveness of fluorouracil and other chemotherapeutic agents.
NCI

A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39229&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39229&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C445″ NCI Thesaurus)
PDQ

A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. (NCI04)
NCI

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kyseliny mastné neesterifikované

FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.
MSH

fatty acids found in the plasma that are complexed with serum albumin for transport; these fatty acids are not in glycerol ester form.
CSP

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prenazon

A pyrazole that has analgesic, anti-inflammatory, and antipyretic properties. It has been used in mild to moderate pain, fever, and inflammation associated with musculoskeletal and joint disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p15)
MSH

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beta-galaktosidasa

A group of enzymes that catalyzes the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-galactosides. Deficiency of beta-Galactosidase A1 may cause GANGLIOSIDOSIS, GM1.
MSH

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jazyk (prostředek komunikace)

A verbal or nonverbal means of communicating ideas or feelings.
MSH

systematic means of communicating by the use of sounds or conventional symbols; broadly includes phonetics, syntax, semantics, pragmatics, and linguistics.
CSP

A systematic means of communicating by the use of sounds, symbols, or gestures.
NCI

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17-ketosteroidy

Steroids that contain a ketone group at position 17.
MSH

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Edetic Acid, Disodium Salt

The disodium salt form of edetate, a heavy metal chelating agent with anti-hypercalcemic and anti-arrhythmic properties. Edetate, a heavy metal antagonist, chelates divalent and trivalent metals, forming soluble stable complexes which are readily excreted by the kidneys, thereby can be used to lower serum calcium concentrations. In addition, this agent exerts a negative inotropic effect on the heart through a transiently induced hypocalcemic state, thereby antagonizing the inotropic and chronotropic effects of digitalis glycosides on the ventricles of the heart. Upon ocular administration, edetate exerts its ophthalmic effect by chelating calcium to form soluble complexes, thereby removing corneal calcium deposits.
NCI

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feminizace

Development of female secondary SEX CHARACTERISTICS in the MALE. It is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
MSH

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primidon

An antiepileptic agent related to the barbiturates; it is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite. Adverse effects are reported to be more frequent than with PHENOBARBITAL. (From Martindale, The Extra Pharmacopoeia, 30th ed, p309)
MSH

An analog of phenobarbital with antiepileptic property. Although the mechanism of action has not been fully elucidated, primidone probably exerts its actions, in a manner similar to phenobarbital, via activation of gamma-aminobutyric acid (GABA)-A receptor/chloride ionophore complex, which leads to prolonged and increased frequency of opening of the chloride channel within the receptor complex. This results in an alteration in the electrical activity of the nerve cell membrane, causing hyperpolarization and prevention of partial and tonic-clonic seizures. In addition, this agent is partially metabolized to phenobarbital and phenylethylmalonamide (PEMA), which may also contribute to its anti-seizure properties.
NCI

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bicyklické sloučeniny

chemical compound containing two ring structures.
CSP

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lasalocid

Cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. It is used as a coccidiostat, especially in poultry.
MSH

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