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Onchocerca volvulus

A species of parasitic nematodes widely distributed throughout central Africa and also found in northern South America, southern Mexico, and Guatemala. Its intermediate host and vector is the blackfly or buffalo gnat.
MSH

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nádory ledvin

Tumors or cancers of the KIDNEY.
MSH

new abnormal tissue of the kidney that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
CSP

A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma.
NCI

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životní prostředí – biodegradace

Elimination of ENVIRONMENTAL POLLUTANTS; PESTICIDES and other waste using living organisms, usually involving intervention of environmental or sanitation engineers.
MSH

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oční víčka – nemoci

pathologic condition of either of the two movable folds (upper and lower) that protect the anterior surface of the eyeball or eyelid.
CSP

Your eyelids help protect your eyes. When you blink, your eyelids spread moisture over your eyes. Blinking also helps move dirt or other particles off the surface of the eye. Closing your eyelids when something is coming towards your eyes can protect from injuries.

Like most other parts of your body, your eyelids can get infected, inflamed, or even develop cancer. There are also specific eyelid problems, including

  • Eyelids that turn in or out
  • Eyelids that droop
  • Abnormal blinking or twitching

Treatment of eyelid problems depends on the cause.


MEDLINEPLUS

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sarkolema

The excitable plasma membrane of a muscle cell. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)
MSH

delicate plasma membrane which invests every striated muscle fiber.
CSP

The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers. [ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

The cell membrane of a muscle cell. It is comprised of a plasma membrane coated with collagen fibers embedded in a layer of polysaccharides.
NCI

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DNA-topoisomerasy – typ I

DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.
MSH

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oftalmie sympatická

Granulomatous uveitis which follows in one eye after a penetrating injury to the other eye; the secondarily affected eye is called the sympathizing eye, and the injured eye is called the exciting or activating eye.
MSH

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Klebsiella rhinoscleromatis

A species of facultatively anaerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is nonmotile and oxidase negative. K. rhinoscleromatis is pathogenic and the causative agent of rhinoscleroma, an upper respiratory disease of the nose and pharynx.
NCI

Any bacterial organism that can be assigned to the species Klebsiella rhinoscleromatis.
NCI

A gram-negative, facultatively anaerobic, rod-shaped bacterium found consistently and exclusively in patients with RHINOSCLEROMA and their contacts. Formerly an individual species, it is now considered a subspecies of K. pneumoniae.
MSH

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biomedicínský výzkum

Research that involves the application of the natural sciences, especially biology and physiology, to medicine. (from American Heritage Dictionary, 4th ed)
MSH

Research concerned with the application of biological and physiological principles to clinical medicine.
NCI

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faktor Xa

Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of prothrombin to thrombin in conjunction with other cofactors.
MSH

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Schistosoma haematobium

A species of trematode blood flukes of the family Schistosomatidae which occurs at different stages in development in veins of the pulmonary and hepatic system and finally the bladder lumen. This parasite causes urinary schistosomiasis.
MSH

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dopamin

One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action.
MSH

one of the catecholamine neurotransmitters in the brain; it is derived from tyrosine and is the precursor to norepinephrine and epinephrine; dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement; dopamine receptors mediate its action.
CSP

A monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1 and beta-1 adrenergic receptors. Mediated through myocardial beta-1 adrenergic receptors, dopamine increase heart rate and force, thereby increasing cardiac output. Alpha-1 adrenergic receptor stimulation on vascular smooth muscle, leads to vasoconstriction and results in an increase in systemic vascular resistance. Stimulation of dopaminergic receptors in renal vasculature, leads to renal blood vessel dilation, and an increase in glomerular filtration rate, renal blood flow, sodium excretion, and urine output.
NCI

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Perorální antikoncepce

agent taken orally that prevents conception or diminishes its likelihood; may be designed for either male or female.
CSP

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kyfóza

Deformities of the SPINE characterized by an exaggerated convexity of the vertebral column. The forward bending of the thoracic region usually is more than 40 degrees. This deformity sometimes is called round back or hunchback.
MSH

A disorder characterized by an abnormal increase in the curvature of the thoracic portion of the spine.
NCI

Abnormally increased curvature of the thoracic portion of the spine.
NCI

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bis(chlormethyl)ether

A substance that is an irritant to the eyes and respiratory tract and may be carcinogenic.
MSH

A colorless, flammable, carcinogenic liquid with an extremely suffocating odor. Bis(Chloromethyl) Ether is used in industry as an alkylating agent, a chemical intermediate, a monitoring indicator for the presence of chloromethyl ether, and as a laboratory reagent. This substance is irritating to eyes and mucous membranes and emits toxic vapors of hydrochloric acid and other chlorinated compounds when heated to decomposition. Exposure to Bis(Chloromethyl) ether is associated with higher risk of developing lung cancer, mainly small-cell type, and the risk increases with increasing duration and cumulative exposure. (NCI05)
NCI

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Fanconiho syndrom

A hereditary or acquired form of generalized dysfunction of the PROXIMAL KIDNEY TUBULE without primary involvement of the KIDNEY GLOMERULUS. It is usually characterized by the tubular wasting of nutrients and salts (GLUCOSE; AMINO ACIDS; PHOSPHATES; and BICARBONATES) resulting in HYPOKALEMIA; ACIDOSIS; HYPERCALCIURIA; and PROTEINURIA.
MSH

constellation of clinical and laboratory manifestations produced by generalized proximal tubular insufficiency in the presence of normal, or nearly normal, glomerular filtration.
CSP

A genetic or acquired disorder characterized by impairment of the function of the proximal tubules of the kidney. It results in decreased reabsorption of electrolytes, glucose, amino acids, and other nutrients.
NCI

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školy mateřské

Schools for children usually under five years of age.
MSH

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intravenous administration

injections made into a vein for therapeutic or experimental purposes.
CSP

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organizace – inovace

Introduction of changes which are new to the organization and are created by management.
MSH

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laktamy

Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.
MSH

cyclic amides formed from aminocarboxylic acids by the elimination of water.
CSP

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blastomykóza

A fungal infection that may appear in two forms: 1, a primary lesion characterized by the formation of a small cutaneous nodule and small nodules along the lymphatics that may heal within several months; and 2, chronic granulomatous lesions characterized by thick crusts, warty growths, and unusual vascularity and infection in the middle or upper lobes of the lung.
MSH

infection caused by fungi of the genus Blastomyces.
CSP

A fungal infection caused by inhalation of spores of Blastomyces dermatitidis. It presents with flu-like symptoms including fever, chills, cough, pleuritic chest pain and myalgias. It may lead to a chronic granulomatous pulmonary infection and disseminate to other anatomic sites including skin, nervous system and bones.
NCI

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kyseliny mastné neesterifikované

FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.
MSH

fatty acids found in the plasma that are complexed with serum albumin for transport; these fatty acids are not in glycerol ester form.
CSP

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štíří jedy

Venoms from animals of the order Scorpionida of the class Arachnida. They contain neuro- and hemotoxins, enzymes, and various other factors that may release acetylcholine and catecholamines from nerve endings. Of the several protein toxins that have been characterized, most are immunogenic.
MSH

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léky – rezistence mikrobiální

The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).
MSH

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ortodoncie – přístroje

Devices used for influencing tooth position. Orthodontic appliances may be classified as fixed or removable, active or retaining, and intraoral or extraoral. (Boucher`s Clinical Dental Terminology, 4th ed, p19)
MSH

appliance which is used for the correction, guidance or adjustment of malformed, injured or diseased dentofacial structure; including those which reposition dental bones.
CSP

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jazyk (prostředek komunikace)

A verbal or nonverbal means of communicating ideas or feelings.
MSH

systematic means of communicating by the use of sounds or conventional symbols; broadly includes phonetics, syntax, semantics, pragmatics, and linguistics.
CSP

A systematic means of communicating by the use of sounds, symbols, or gestures.
NCI

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selfmonitoring glykémie

Self evaluation of whole blood glucose levels outside the clinical laboratory. A digital or battery-operated reflectance meter may be used. It has wide application in controlling unstable insulin-dependent diabetes.
MSH

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feminizace

Development of female secondary SEX CHARACTERISTICS in the MALE. It is due to the effects of estrogenic metabolites of precursors from endogenous or exogenous sources, such as ADRENAL GLANDS or therapeutic drugs.
MSH

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sekreční komponent

The extracellular moiety of the POLYMERIC IMMUNOGLOBULIN RECEPTOR found alone or complexed with IGA or IGM, in a variety of external secretions (tears, bile, colostrum.) Secretory component is derived by proteolytic cleavage of the receptor during transcytosis. When immunoglobulins IgA and IgM are bound to the receptor, during their transcytosis secretory component becomes covalently attached to them generating SECRETORY IMMUNOGLOBULIN A or secretory IMMUNOGLOBULIN M.
MSH

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DUODENO ULTZERA

A PEPTIC ULCER located in the DUODENUM.
MSH

peptic ulcer located in the duodenum, the shortest and widest portion of the small intestine adjacent to the pylorus of the stomach.
CSP

A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the mucosal surface of the duodenal wall.
NCI

An ulcer in the duodenal wall.
NCI

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