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inosinmonofosfát

Inosine 5`-Monophosphate. A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.
MSH

purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.
CSP

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protilátky – tvorba

The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.
MSH

synthesis of antibodies in response to B-cell activation by antigens; includes genetic regulation, recombination, all aspects of gene expression of the antibodies as well as the proliferation and differentiation of the B lymphocytes into plasma cells or memory cells.
CSP

The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add, ISBN:0781735149 “Fundamental Immunology”]
GO

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testikulární hormony

Hormones produced in the testis.
MSH

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vícenenasycené mastné kyseliny

fatty acid containing more than one double bond (C=C). The essential fatty acids omega-3 and omega-6 are polyunsaturated fatty acids (PUFAs) that contain 2 or more cis double bonds. Dietary intake of some PUFAs may have beneficial effects on blood pressure, serum lipds, and inflammation. Some PUFAs, such as omega-3 PUFAs, may have antineoplastic or chemopreventive activities.
NCI

A class of dietary fatty acids containing two or more double bonds.
NCI

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cykloserin

Antibiotic substance produced by Streptomyces garyphalus.
MSH

An analogue of the amino acid D-alanine with broad-spectrum antibiotic and glycinergic activities. D-cycloserine interferes with bacterial cell wall synthesis by competitively inhibiting two enzymes, L-alanine racemase and D-alanine:D-alanine ligase, thereby impairing peptidoglycan formation necessary for bacterial cell wall synthesis. This agent may be bactericidal or bacteriostatic, depending on its concentration at the infection site and the susceptibility of the organism. In addition, D-cycloserine is an excitatory amino acid and partial agonist at the glycine binding site of the NMDA receptor in the central nervous system (CNS); binding to the central NMDA receptor may result in amelioration of neuropathic pain.
NCI

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ústavní praxe

Professional practice as an employee or contractee of a health care institution.
MSH

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antigeny diferenciační myelomonocytární

Surface antigens expressed on myeloid cells of the granulocyte-monocyte-histiocyte series during differentiation. Analysis of their reactivity in normal and malignant myelomonocytic cells is useful in identifying and classifying human leukemias and lymphomas.
MSH

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Tetrahymena pyriformis

A species of ciliate protozoa used extensively in genetic research.
MSH

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portální systém

A system of vessels in which blood, after passing through one capillary bed, is conveyed through a second set of capillaries before it returns to the systemic circulation. It pertains especially to the hepatic portal system.
MSH

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cysteinové endopeptidasy

ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.
MSH

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pojištění při dlouhodobé péči

Health insurance to provide full or partial coverage for long-term home care services or for long-term nursing care provided in a residential facility such as a nursing home.
MSH

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antitumorózní látky fytogenní

Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
MSH

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epidemiologické faktory

Events, characteristics, or other definable entities that have the potential to bring about a change in a health condition or other defined outcome.
MSH

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theobromin

3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
MSH

3,7-dimethylxanthine, an alkaloid found in coca with properties similar to caffeine and theophylline.
CSP

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draslík – isotopy

Stable potassium atoms that have the same atomic number as the element potassium, but differ in atomic weight. K-41 is a stable potassium isotope.
MSH

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cytochromy b5

Cytochromes of the b group that are found bound to cytoplasmic side of ENDOPLASMIC RETICULUM. They serve as electron carrier proteins for a variety of membrane-bound OXYGENASES. They are reduced by the enzyme CYTOCHROME-B(5) REDUCTASE.
MSH

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interleukin-3

A multilineage cell growth factor secreted by LYMPHOCYTES; EPITHELIAL CELLS; and ASTROCYTES which stimulates clonal proliferation and differentiation of various types of blood and tissue cells.
MSH

lymphokine produced by antigen or mitogen activated T lymphocytes which stimulates proliferation of hematopoietic as well as lymphoid stem cells; a colony stimulating factor for bone marrow progenitor cells; supports growth and differentiation of early hematopoieteic and lymphoid stem cells as well as that of more mature hematopoietic cells, including granulocytes, macrophages and mast cells.
CSP

One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-3 is made mainly by a type of T lymphocyte. It increases the number of blood cells made by the bone marrow. IL-3 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. IL-3 is a type of cytokine.
NCI

A group of proteins that causes blood cells to grow and mature.
NCI

Human interleukin-3 (152 aa, 17 kDa precursor) is encoded by the human interleukin-3 (IL3) gene. This protein is a potent growth-promoting cytokine that enhances the ability of the immune system to fight tumor cells. IL-3 supports proliferation of many hematopoietic cell types. It is involved in cell growth, differentiation and apoptosis in addition to possessing neurotrophic activity. Abnormalities in this protein may be associated with neurologic disorders.
NCI

Endogenous growth factors which promote the development of blood cells.
NCI

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anus – nádory

Tumors or cancer of the ANAL CANAL.
MSH

A benign or malignant neoplasm involving the anus.
NCI

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epispadie

A birth defect due to malformation of the URETHRA in which the urethral opening is above its normal location. In the male, the malformed urethra generally opens on the top or the side of the PENIS, but the urethra can also be open the entire length of the penis. In the female, the malformed urethral opening is often between the CLITORIS and the labia, or in the ABDOMEN.
MSH

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thiamintrifosfát

3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P`,P“-trioxide. The triphosphate ester of thiamine. In Leigh`s disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation.
MSH

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prealbumin

A tetrameric protein, molecular weight between 50,000 and 70,000, consisting of 4 equal chains, and migrating on electrophoresis in 3 fractions more mobile than serum albumin. Its concentration ranges from 7 to 33 per cent in the serum, but levels decrease in liver disease.
MSH

Transthyretin (147 aa, ~16 kDa) is encoded by the human TTR gene. This protein is involved in both the binding and transport of retinol and thyroxine.
NCI

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cytoplazmatická granula

Condensed areas of cellular material that may be bounded by a membrane.
MSH

insoluble nonmembranous particles found in cytoplasm.
CSP

Any small grainlike particle.
NCI

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meziobratlová ploténka – výhřez

An INTERVERTEBRAL DISC in which the nucleus pulposus has protruded through surrounding fibrocartilage. This occurs most frequently in the lower lumbar region.
MSH

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Brocova afázie

An aphasia characterized by impairment of expressive language (speech, writing, signs) and relative preservation of receptive language abilities (i.e., comprehension). This condition is caused by lesions of the motor association cortex in the frontal lobe (Broca`s area and adjacent cortical and white matter regions). The deficits range from almost complete muteness to a reduction in the fluency and rate of speech. CEREBROVASCULAR ACCIDENTS (in particular INFARCTION, MIDDLE CEREBRAL ARTERY) are a relatively common cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp478-9)
MSH

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Ergocalciferol

Vitamin D synthesized from 7-dehydrocholesterol in the skin after exposure to UVB radiation.
NCI

A form of vitamin D that helps the body use calcium and phosphorus to make strong bones and teeth. It is fat-soluble (can dissolve in fats and oils) and is found in plants and yeast. It can be made in the body from another form of vitamin D when the body is exposed to the sun. Ergocalciferol is also made in the laboratory. It is used to prevent and to treat vitamin D deficiency. It is a type of dietary supplement.
NCI

Vitamin D2, a fat-soluble vitamin important for many biochemical processes including the absorption and metabolism of calcium and phosphorus. In vivo, ergocalciferol is formed after sun (ultraviolet) irradiation of plant-derived ergosterol, another form of vitamin D. Ergocalciferol is the form of vitamin D usually found in vitamin supplements. (NCI04)
NCI

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thioridazin

A phenothiazine antipsychotic used in the management of PHYCOSES, including SCHIZOPHRENIA.
MSH

phenothiazine compound having antipsychotic and sedative effects, used in treatment of schizophrenia and acute psychotic episodes, for relief of anxiety, agitiation and depression in mood disorders, and for treatment of disruptive behavior disorders in children.
CSP

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těhotenství – trimestry

The three approximately equal periods of a normal human PREGNANCY. Each trimester is about three months or 13 to 14 weeks in duration depending on the designation of the first day of gestation.
MSH

A period of three months; especially one of the three three-month periods into which human pregnancy is divided.
NCI

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interpretace statistických dat

Application of statistical procedures to analyze specific observed or assumed facts from a particular study.
MSH

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nitroděložní antikoncepční prostředky měděné

Intrauterine contraceptive devices that depend on the release of metallic copper.
MSH

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meruňka

Prunus armeniaca L. is the source of apricots.
MSH

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