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kyanidy

Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.
MSH

class of compounds derived from HCN containing the -CN radical.
CSP

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hnůj

Accumulations of solid or liquid animal excreta usually from stables and barnyards with or without litter material. Its chief application is as a fertilizer. (From Webster`s 3d ed)
MSH

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protilátky – tvorba

The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS.
MSH

synthesis of antibodies in response to B-cell activation by antigens; includes genetic regulation, recombination, all aspects of gene expression of the antibodies as well as the proliferation and differentiation of the B lymphocytes into plasma cells or memory cells.
CSP

The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:add, ISBN:0781735149 “Fundamental Immunology”]
GO

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pohlavní orgány ženské – nádory

Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).
MSH

new abnormal tissue of the female reproductive system that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
CSP

Cancer in the human female`s reproductive organs
NCI

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trombastenie

A congenital bleeding disorder with prolonged bleeding time, absence of aggregation of platelets in response to most agents, especially ADP, and impaired or absent clot retraction. Platelet membranes are deficient in or have a defect in the glycoprotein IIb-IIIa complex (PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX).
MSH

platelet abnormality characterized by defective clot formation, impaired aggregation, and prolonged bleeding time; other manifestations include nosebleeds, inappropriate bruising, and excessive bleeding.
CSP

A rare, autosomal recessive inherited and less frequently acquired platelet disorder. It is characterized by deficient or dysfunctional glycoprotein IIb/IIIa complex. It leads to defective platelet aggregation, resulting in bleeding.
NCI

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prenazon

A pyrazole that has analgesic, anti-inflammatory, and antipyretic properties. It has been used in mild to moderate pain, fever, and inflammation associated with musculoskeletal and joint disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p15)
MSH

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cykloserin

Antibiotic substance produced by Streptomyces garyphalus.
MSH

An analogue of the amino acid D-alanine with broad-spectrum antibiotic and glycinergic activities. D-cycloserine interferes with bacterial cell wall synthesis by competitively inhibiting two enzymes, L-alanine racemase and D-alanine:D-alanine ligase, thereby impairing peptidoglycan formation necessary for bacterial cell wall synthesis. This agent may be bactericidal or bacteriostatic, depending on its concentration at the infection site and the susceptibility of the organism. In addition, D-cycloserine is an excitatory amino acid and partial agonist at the glycine binding site of the NMDA receptor in the central nervous system (CNS); binding to the central NMDA receptor may result in amelioration of neuropathic pain.
NCI

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davové chování

Collective behavior of an aggregate of individuals giving the appearance of unity of attitude, feeling, and motivation.
MSH

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antigeny diferenciační myelomonocytární

Surface antigens expressed on myeloid cells of the granulocyte-monocyte-histiocyte series during differentiation. Analysis of their reactivity in normal and malignant myelomonocytic cells is useful in identifying and classifying human leukemias and lymphomas.
MSH

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Německo

central European country bordering on the North and Baltic Seas, capital Berlin.
CSP

A country in Central Europe, bordering the Baltic Sea and the North Sea, between the Netherlands and Poland, south of Denmark. (NCI)
NCI

Description:Realm code for use of Germany


HL7V3.0

A country in Central Europe, bordering the Baltic Sea and the North Sea, between the Netherlands and Poland, south of Denmark. (CIA World Factbook 2002)
NCI

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17-ketosteroidy

Steroids that contain a ketone group at position 17.
MSH

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primidon

An antiepileptic agent related to the barbiturates; it is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite. Adverse effects are reported to be more frequent than with PHENOBARBITAL. (From Martindale, The Extra Pharmacopoeia, 30th ed, p309)
MSH

An analog of phenobarbital with antiepileptic property. Although the mechanism of action has not been fully elucidated, primidone probably exerts its actions, in a manner similar to phenobarbital, via activation of gamma-aminobutyric acid (GABA)-A receptor/chloride ionophore complex, which leads to prolonged and increased frequency of opening of the chloride channel within the receptor complex. This results in an alteration in the electrical activity of the nerve cell membrane, causing hyperpolarization and prevention of partial and tonic-clonic seizures. In addition, this agent is partially metabolized to phenobarbital and phenylethylmalonamide (PEMA), which may also contribute to its anti-seizure properties.
NCI

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cysteinové endopeptidasy

ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.
MSH

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správa materiálů v nemocnici

The management of all procurement, distribution, and storage of equipment and supplies, as well as logistics management including laundry, processing of reusables, etc.
MSH

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antitumorózní látky fytogenní

Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
MSH

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dásně – hypertrofie

Abnormal enlargement or overgrowth of the gingivae brought about by enlargement of existing cells.
MSH

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3,4-methylendioxyamfetamin

An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.
MSH

abused, controlled, serotonergic hallucinogen of the “designer drug” class; probably the active metabolite of MDMA (“ecstasy”).
CSP

a kind of hallucinogenic drug
CHV

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proktoskopy

Endoscopes for visual examination of the rectum and anus.
MSH

An endoscope and accessories is a device used to provide access, illumination, and allow observation or manipulation of body cavities, hollow organs, and canals. The device consists of various rigid or flexible instruments that are inserted into body spaces and may include an optical system for conveying an image to the user`s eye and their accessories may assist in gaining access or increase the versatility and augment the capabilities of the devices. Examples of devices that are within this generic type of device include cleaning accessories for endoscopes, photographic accessories for endoscopes, nonpowered anoscopes, binolcular attachments for endoscopes, pocket battery boxes, flexible or rigid choledochoscopes, colonoscopes, diagnostic cystoscopes, cystourethroscopes, enteroscopes, esophagogastroduodenoscopes, rigid esophagoscopes, fiberoptic illuminators for endoscopes, incandescent endoscope lamps, biliary pancreatoscopes, proctoscopes, resectoscopes, nephroscopes, sigmoidoscopes, ureteroscopes, urethroscopes, endomagnetic retrievers, cytology brushes for endoscopes, and lubricating jelly for transurethral surgical instruments. This section does not apply to endoscopes that have specialized uses in other medical specialty areas and that are covered by classification regulations in other parts of the device classification regulations.
SPN

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cytochromy b5

Cytochromes of the b group that are found bound to cytoplasmic side of ENDOPLASMIC RETICULUM. They serve as electron carrier proteins for a variety of membrane-bound OXYGENASES. They are reduced by the enzyme CYTOCHROME-B(5) REDUCTASE.
MSH

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maytansin

An ansa macrolide isolated from the MAYTENUS genus of East African shrubs.
MSH

An ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata. Maytansine binds to tubulin at the rhizoxin binding site, thereby inhibiting microtubule assembly, inducing microtubule disassembly, and disrupting mitosis. Maytansine exhibits cytotoxicity against many tumor cell lines and may inhibit tumor growth in vivo. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39492&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39492&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C626″ NCI Thesaurus)
PDQ

An ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata. Maytansine binds to tubulin at the rhizoxin binding site, thereby inhibiting microtubule assembly, inducing microtubule disassembly, and disrupting mitosis. Maytansine exhibits cytotoxicity against many tumor cell lines and may inhibit tumor growth in vivo. (NCI04)
NCI

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anus – nádory

Tumors or cancer of the ANAL CANAL.
MSH

A benign or malignant neoplasm involving the anus.
NCI

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glomerulární filtrace – hodnota

The volume of water filtered out of plasma through glomerular capillary walls into Bowman`s capsules per unit of time. It is considered to be equivalent to INULIN clearance.
MSH

rate at which plasma is filtered by the glomerular filtration membrane into Bowman`s space; determined by the permeabiliy of the membrane, hydrostatic pressure in the glomerular capillaries and Bowman`s space, and the colloid osmotic pressure exerted by the proteins of the capillary plasma.
CSP

A kidney function test that measures the fluid volume that is filtered from the kidney glomeruli to the Bowman`s capsule per unit of time.
NCI

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6-merkaptopurin

An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
MSH

A drug used to treat acute lymphatic leukemia. It belongs to the family of drugs called antimetabolites.
NCI

A thiopurine-derivative antimetabolite with antineoplastic and immunosuppressive activities. Produced through the metabolism of mercaptopurine by hypoxanthine-guanine phosphoribosyltransferase (HGPRT), mercaptopurine metabolites 6-thioguanosine-5`-phosphate (6-thioGMP) and 6-thioinosine (T-IMP) inhibit nucleotide interconversions and de novo purine synthesis, thereby blocking the formation of purine nucleotides and inhibiting DNA synthesis. This agent is also incorporated into DNA in the form of deoxythioguanosine, which results in the disruption of DNA replication. In addition, mercaptopurine is converted to 6-methylmercaptopurine ribonucleoside (MMPR) by 6-thiopurine methyltransferase; MMPRs are also potent inhibitors of de novo purine synthesis. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43436&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43436&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C195″ NCI Thesaurus)
PDQ

A thiopurine-derivative antimetabolite with antineoplastic and immunosuppressive activities. Produced through the metabolism of mercaptopurine by hypoxanthine-guanine phosphoribosyltransferase (HGPRT), mercaptopurine metabolites 6-thioguanosine-5`-phosphate (6-thioGMP) and 6-thioinosine monophosphate (T-IMP) inhibit nucleotide interconversions and de novo purine synthesis, thereby blocking the formation of purine nucleotides and inhibiting DNA synthesis. This agent is also incorporated into DNA in the form of deoxythioguanosine, which results in the disruption of DNA replication. In addition, mercaptopurine is converted to 6-methylmercaptopurine ribonucleoside (MMPR) by 6-thiopurine methyltransferase; MMPRs are also potent inhibitors of de novo purine synthesis. (NCI04)
NCI

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programovací jazyk

Specific languages used to prepare computer programs.
MSH

A formal language in which computer programs are written. The definition of a particular language consists of both syntax (how the various symbols of the language may be combined) and semantics (the meaning of the language constructs). (Free On-Line Dictionary of Computing)
NCI

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cytoplazmatická granula

Condensed areas of cellular material that may be bounded by a membrane.
MSH

insoluble nonmembranous particles found in cytoplasm.
CSP

Any small grainlike particle.
NCI

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lékařská podpora, oddíl 19

Federal program, created by Public Law 89-97, Title XIX, a 1965 amendment to the Social Security Act, administered by the states, that provides health care benefits to indigent and medically indigent persons.
MSH

A joint federal and state program that provides assistance with healthcare costs to people with low income and limited resources. Medicaid is run by state and local governments within federal guidelines. Healthcare bills are paid from federal, state and local tax funds. The eligibility for the program does not depend on a person`s age. Participating beneficiaries usually pay no part of costs for covered healthcare expenses except a small co-payment required in some cases.
NCI

Medicaid is government health insurance that helps many low-income people in the United States to pay their medical bills. Although the Federal government establishes general guidelines for the program, each state has its own rules. Your state might require you to pay a small part of the cost for some medical services.

You have to meet certain requirements to be eligible for Medicaid. These might involve

  • Your age
  • Whether you are pregnant, disabled or blind
  • Your income and resources
  • Whether or not you are a U.S. citizen or a lawfully admitted immigrant

Centers for Medicare and Medicaid Services


MEDLINEPLUS

A health insurance program for people who cannot afford regular medical care. The program is run by U.S. federal, state, and local governments. People who receive Medicaid may have to pay a small amount for the services they get.
NCI

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Brocova afázie

An aphasia characterized by impairment of expressive language (speech, writing, signs) and relative preservation of receptive language abilities (i.e., comprehension). This condition is caused by lesions of the motor association cortex in the frontal lobe (Broca`s area and adjacent cortical and white matter regions). The deficits range from almost complete muteness to a reduction in the fluency and rate of speech. CEREBROVASCULAR ACCIDENTS (in particular INFARCTION, MIDDLE CEREBRAL ARTERY) are a relatively common cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp478-9)
MSH

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glukosa – roztok hypertonický

Solution that is usually 10 percent glucose but may be higher. An isotonic solution of glucose is 5 percent.
MSH

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slez

The fourth stomach of ruminating animals. It is also called the “true” stomach. It is an elongated pear-shaped sac lying on the floor of the abdomen, on the right-hand side, and roughly between the seventh and twelfth ribs. It leads to the beginning of the small intestine. (From Black`s Veterinary Dictionary, 17th ed)
MSH

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propanil

A chlorinated anilide that is used as an herbicide.
MSH

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