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Acepromazine Maleate

The maleate salt of acepromazine, a phenothiazine derivative with depressant effect on the central nervous system. Acepromazine acts as a dopamine receptor antagonist in the CNS, thereby causing sedation, muscular relaxation and a reduction in spontaneous activity. Its fast-acting neuroleptic effect with low toxicity is of particular value in veterinary medicine.
NCI

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antigeny diferenciační

Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation.
MSH

antigens normally only seen at particular phases of differentiation of a cell type.
CSP

Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation. (MeSH)
NCI

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prostata – nádory

Tumors or cancer of the PROSTATE.
MSH

new abnormal prostate tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
CSP

A benign or malignant tumor involving the prostate gland.
NCI

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methoxyfluran

An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with NITROUS OXIDE to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180)
MSH

highly potent inhalation anesthetic used primarily to produce analgesia during the first stage of labor; use limited by dose related nephrotoxicity.
CSP

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vláskové buňky vnitřní

Auditory sensory cells of organ of Corti, usually placed in one row medially to the core of spongy bone (the modiolus). Inner hair cells are in fewer numbers than the OUTER AUDITORY HAIR CELLS, and their STEREOCILIA are approximately twice as thick as those of the outer hair cells.
MSH

A cell situated on the inner most layer of the basilar membrane of the cochlea. Each cell has multiple, sensitive strands called stereocilia. In the resting state the stereocilia are leaning on each other in a conical bundle and touch the tectorial membrane. When the cochlea moves in response to sound, a slight shearing force occurs between the basilar and tectorial membranes, the stereocilia bend and send electrical impulses to the brain via the eighth cranial nerve.
NCI

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kaspasy

A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.
MSH

The caspases are a family of proteases responsible for carrying out the cell death process. In a living cell, these proteases are kept inactive by proteins on the mitochondrial cell surface from the BcL-2 family. When a cell is exposed to cell death signals such as ischemia, chemotherapy or radiation, BcL-2 function is blocked and caspase activators initiate the cell death cascade.
NCI

Caspases are a family of intracellular cysteine proteinases involved in inflammation and apoptosis. These enzymes appear to be involved in the initial signaling events, as well as the downstream proteolytic cleavages, that result in apoptotic cell death. They are specific for aspartic acid at the P1 position and are divided into two classes based on the lengths of their N-terminal pro-domains. Caspases-1, -2, -4, -5, -8, and -10 have long pro-domains; caspases-3, -6, -7, and -9 have short pro-domains. (from Science 1998. 281:1312 and Br Med Bull 1997. 53:478)
NCI

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acetylkarnitin

An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.
MSH

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antitumorózní látky

Substances that inhibit or prevent the proliferation of NEOPLASMS.
MSH

agent that inhibits or prevents the development or proliferation of neoplasms.
CSP

A drug used to treat cancer.
NCI

NOTE: Includes hormones (AN500) which are exclusively used as antineoplastics (e.g.,tamoxifen). Excludes other hormones (HS000).
NDFRT

A substance that inhibits the maturation, growth or spread of tumor cells.
NCI

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exsudativní enteropatie

Pathological conditions in the INTESTINES that are characterized by the gastrointestinal loss of serum proteins, including SERUM ALBUMIN; IMMUNOGLOBULINS; and at times LYMPHOCYTES. Severe condition can result in HYPOGAMMAGLOBULINEMIA or LYMPHOPENIA. Protein-losing enteropathies are associated with a number of diseases including INTESTINAL LYMPHANGIECTASIS; WHIPPLE`S DISEASE; and NEOPLASMS of the SMALL INTESTINE.
MSH

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nordefrin

A norepinephrine derivative used as a vasoconstrictor agent.
MSH

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nemoc rukou, nohou a úst

A mild, highly infectious viral disease of children, characterized by vesicular lesions in the mouth and on the hands and feet. It is caused by coxsackieviruses A.
MSH

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cytochemie

Branch of histochemistry associated with the localization of cellular components by specific staining methods, as for example the localization of acid phosphatases by the Gomori method.
NCI

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renální tubulární acidóza

A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.
MSH

rare sometimes familial disorder of the renal tubule characterized by the inability to excrete urine of normal acidity; this leads to a hyperchloremic acidosis which is often associated with one or more secondary complications such as hypercalcinuria with nephrolithiasis and nephrocalcinosis, rickets, or osteomalacia and severe potassium depletion.
CSP

A rare disorder in which structures in the kidney that filter the blood are impaired, producing urine that is more acid than normal.
NCI

Failure of the renal tubules of the kidney to excrete urine of normal acidity resulting in metabolic acidosis. It may lead to hypercalcinuria, nephrolithiasis, and renal failure. Causes include autoimmune disorders (e.g., Sjogren syndrome, systemic lupus erythematosus, and rheumatoid arthritis), medications (e.g., non steroidal anti-inflammatory drugs, diuretics, and blood pressure medications), Fanconi syndrome, or it may be familiar.
NCI

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anus

The lower opening of the digestive tract, lying in the cleft between the buttocks, through which fecal matter is extruded.
NCI

The opening of the rectum to the outside of the body.
NCI

The lower opening of the digestive tract, lying in the cleft between the buttocks, through which fecal matter is extruded. (NCI)
NCI

The external outlet of the GASTROINTESTINAL TRACT.
MSH

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prune belly syndrom

A syndrome characterized by abdominal wall musculature deficiency, cryptorchism, and urinary tract abnormalities. The syndrome derives its name from its characteristic distended abdomen with wrinkled skin.
MSH

A rare congenital syndrome occurring almost exclusively in males. It is characterized by partial or complete lack of the abdominal wall muscles, enlarged bladder, dilated ureters, hydronephrosis, and undescended testes.
NCI

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Mus musculus

the scientific name of the common house mouse; for inbred and mutant strain mice used in research, use LABORATORY MOUSE or narrower terms.
CSP

The common house mouse, often used as an experimental organism.
NCI

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nemocenské dávky pracujícím – plány

Health insurance plans for employees, and generally including their dependents, usually on a cost-sharing basis with the employer paying a percentage of the premium.
MSH

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cytofotometrie

A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
MSH

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akromion

The lateral extension of the spine of the SCAPULA and the highest point of the SHOULDER.
MSH

The upper distal process of the scapula. (NCI)
NCI

The upper distal process of the scapula.
NCI

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afakie po kataraktě

Absence of the crystalline lens resulting from cataract extraction.
MSH

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pseudoxanthoma elasticum

An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.
MSH

rare, progressive inherited disorder resulting from extensive basophilic degeneration of elastic tissue, usually presenting after puberty and involving the skin, eye, and cardiovascular system.
CSP

A rare, progressive, autosomal recessive inherited disorder caused by mutations in the ABCC6 gene. It is characterized by calcification and fragmentation of the elastic fibers of the skin, retina, and cardiovascular system. Signs and symptoms include skin plaques and bumps, thickened skin, retinal hemorrhage and obstruction of the blood vessels.
NCI

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mikrofilamentové proteiny

Monomeric subunits of primarily globular ACTIN and found in the cytoplasmic matrix of almost all cells. They are often associated with microtubules and may play a role in cytoskeletal function and/or mediate movement of the cell or the organelles within the cell.
MSH

Structurally complex proteins that are comprised of microfilaments, which are necessary components of the cellular cytoskeleton for motility and shape. Microfilaments physically associate with microtubules to play a structural role in cytoskeleton integrity.
NCI

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zdravotnictví – zdroje

Available manpower, facilities, revenue, equipment, and supplies to produce requisite health care and services.
MSH

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sběr dat

Systematic gathering of data for a particular purpose from various sources, including questionnaires, interviews, observation, existing records, and electronic devices. The process is usually preliminary to statistical analysis of the data.
MSH

gathering or assemblage of information (statistics or measurements) about a system, population, etc.; do not confuse with SAMPLE COLLECTION (PHYSICAL).
CSP

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pojišťovací analýza

The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs.
MSH

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schůzky a rozvrhy

The different methods of scheduling patient visits, appointment systems, individual or group appointments, waiting times, waiting lists for hospitals, walk-in clinics, etc.
MSH

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psychologie práce

The branch of applied psychology concerned with the application of psychologic principles and methods to industrial problems including selection and training of workers, working conditions, etc.
MSH

The branch of applied psychology that is concerned with efficient management of an industrial labor force and especially with problems encountered by workers in a mechanized environment. (Bartleby.com)
NCI

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mikrotomie

The technique of using a microtome to cut thin or ultrathin sections of tissues embedded in a supporting substance. The microtome is an instrument that hold a steel, glass or diamond knife in clamps at an angle to the blocks of prepared tissues, which it cuts in sections of equal thickness.
MSH

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srdce – katetrizace

Procedure which includes placement of catheter, recording of intracardiac and intravascular pressure, obtaining blood samples for chemical analysis, and cardiac output measurement, etc. Specific angiographic injection techniques are also involved.
MSH

procedure which includes insertion of a tubular device into the heart for recording of intracardiac and intravascular pressure, obtaining blood samples for chemical analysis, and cardiac output measurement, injecting or withdrawing fluids, etc.
CSP

A procedure in which a thin plastic tube (catheter) is inserted into an artery or vein in the arm or leg and then advanced into the chambers of the heart or into the coronary arteries. Catheterization can measure blood pressure within the heart and how much oxygen is in the blood. It`s also used to get information about the pumping ability of the heart muscle. Catheters are also used to inject dye into the coronary arteries. Catheters with a balloon on the tip are used in the procedure called percutaneous transluminal coronary angioplasty.
NCI

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decidua

The hormone-responsive glandular layer of ENDOMETRIUM that sloughs off at each menstrual flow (decidua menstrualis) or at the termination of pregnancy. During pregnancy, the thickest part of the decidua forms the maternal portion of the PLACENTA, thus named decidua placentalis. The thin portion of the decidua covering the rest of the embryo is the decidua capsularis.
MSH

endometrium of the pregnant uterus; shed at parturition, except for the deepest layer.
CSP

The epithelial tissue of the endometrium.
NCI

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