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retinální pigmenty

Photosensitive protein complexes of varied light absorption properties which are expressed in the PHOTORECEPTOR CELLS. They are OPSINS conjugated with VITAMIN A-based chromophores. Chromophores capture photons of light, leading to the activation of opsins and a biochemical cascade that ultimately excites the photoreceptor cells.
MSH

photopigments in retinal rods and cones that respond to certain colors of light and initiate the process of vision.
CSP

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končetiny dolní – dermatózy

A nonspecific term used to denote any cutaneous lesion or group of lesions, or eruptions of any type on the leg. (From Stedman, 25th ed)
MSH

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krotonový olej

Viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae). It is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality.
MSH

viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae); a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy; causes skin cancer; was formerly used as an emetic and cathartic with frequent mortality.
CSP

A yellow to brown colored, thick, foul smelling, very toxic oil obtained from the seeds of a tropical plant, Croton Tiglium. Croton oil was used as a drastic purgative agent, but is now mostly used as a standard irritant in pharmacological research. Exposure to this substance causes severe skin irritation and affects the small intestine leading to severe diarrhea. Croton oil is a possible human carcinogen. (NCI05)
NCI

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fibrinogen

Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
MSH

plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds; fibrinogen clotting is a sol-gel change involving complex molecular arrangements.
CSP

A fibrillar protein present in blood plasma; it converts to fibrin during the process of blood clot formation.
NCI

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přední komora oční

The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)
MSH

space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil.
CSP

The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)
NCI

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Rh izoimunizace

The process by which fetal Rh+ erythrocytes enter the circulation of an Rh- mother, causing her to produce IMMUNOGLOBULIN G antibodies, which can cross the placenta and destroy the erythrocytes of Rh+ fetuses. Rh isoimmunization can also be caused by BLOOD TRANSFUSION with mismatched blood.
MSH

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Leishmania tropica

A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and rodents. This taxonomic complex includes species which cause a disease called Oriental sore which is a form of cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) of the Old World.
MSH

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kulturní charakteristiky

Those aspects or characteristics which identify a culture.
MSH

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filarióza

Infections with nematodes of the superfamily FILARIOIDEA. The presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis. Organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischemic necrosis of the brain, blindness, and dermatosis of the face.
MSH

infections with nematodes of the superfamily Filarioidea; presence of living worms in the body is mainly asymptomatic but the death of adult worms leads to granulomatous inflammation and permanent fibrosis; organisms of the genus Elaeophora infect wild elk and domestic sheep causing ischaemic necrosis of the brain, blindness, and dermatosis of the face.
CSP

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aurodox

Antibiotic obtained from a Streptomyces variant considered as possibly effective against Streptococcus pyogenes infections. It may promote growth in poultry.
MSH

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Rhizopus

A genus of zygomycetous fungi of the family Mucoraceae, order MUCORALES, a common saprophyte and facultative parasite of mature fruits and vegetables. It may cause cerebral mycoses in diabetes and cutaneous infection in severely burned patients.
MSH

A genus of filamentous fungi in the phylum Zygomycota.
NCI

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Leptospira interrogans

A genus of question mark-shaped bacteria spirochetes which is found in fresh water that is contaminated by animal urine. It causes LEPTOSPIROSIS.
MSH

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proteinkinasy závislé na cyklickém AMP

A group of enzymes that are dependent on CYCLIC AMP and catalyze the phosphorylation of SERINE or THREONINE residues on proteins. Included under this category are two cyclic-AMP-dependent protein kinase subtypes, each of which is defined by its subunit composition.
MSH

nonEC; enzyme is stimulated by intracellular cyclic AMP, and therefore links that important second messenger system to the equally important protein phosphorylation cascade for transducing biological signals.
CSP

Most cellular effects of cAMP are mediated through PKA by serine or threonine phosphorylation of target proteins. Human Protein Kinase A (cAMP Ser/Thr Protein Kinase Family) is an inactive tetrameric cytoplasmic holoenzyme composed of homo- or heterodimeric regulatory subunits associated with two catalytic subunits. cAMP causes dissociation of inactive holoenzyme into a cAMP-bound dimer of regulatory subunits and two free monomeric catalytic subunits that phosphorylate many cytoplasmic and nuclear substrates. In human, regulatory PRKAR1A, PRKAR1B, PRKAR2A, and PRKAR2B subunits and catalytic PRKACA, PRKACB, and PRKACG subunits have been identified. (NCI)
NCI

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ryby

A group of cold-blooded, aquatic vertebrates having gills, fins, a cartilaginous or bony endoskeleton, and elongated bodies covered with scales.
MSH

any of numerous cold-blooded strictly aquatic craniate vertebrates that include the bony fishes and usually the cartilaginous and jawless fishes and that have typically an elongated somewhat spindle-shaped body terminating in a broad caudal fin, limbs in the form of fins when present at all, and a 2-chambered heart by which blood is sent through thoracic gills to be oxygenated.
CSP

A grouping of jawed and jawless vertebrate animals usually having fins and a covering of scales or plates, breathing by means of gills, and living almost entirely in the water.
NCI

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antidepresiva

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
MSH

mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
CSP

A drug used to treat depression.
NCI

Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Medicines sometimes cause unwanted side effects. For example, when you first start your antidepressant you may feel tired, have trouble sleeping or feel sick to your stomach. The side effects usually go away after a short time. Tell your doctor if you have any side effects. You should also let your doctor know if you take any other medicines, vitamins or herbal supplements.

It is important to keep taking your medicines, even if you feel better. Do not stop taking your medicines without talking to your doctor. You often need to stop antidepressants gradually.

NIH: National Institute of Mental Health


MEDLINEPLUS

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several monoamine oxidase inhibitors are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents also appear to act through brain catecholamine systems. A third group is a diverse group of drugs including some that act specifically on serotonergic systems. (MeSH)
NCI

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ribosamonofosfáty

Ribose substituted in the 1-, 3-, or 5-position by a phosphoric acid moiety.
MSH

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leukémie monocytární akutní

An acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage including monoblasts, promonocytes, and MONOCYTES.
MSH

Acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage. Bleeding disorders are common presenting features. It usually follows an aggressive clinical course. (WHO, 2001) — 2003
NCI

uncommon form of acute myelogenous leukemia, in which the predominating cells are identified as monocytes; a few myelocytes may be present, but not as many as in acute myelomonocytic leukemia.
CSP

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Severozápadní teritoria

A federally administered division of Canada. Its capital is Yellowknife. The former northern and eastern-most parts of the Territory comprise the new territory of Nunavut, effective April 1, 1999.
MSH

A province in northwest Canada bordering Yukon to the west and Nunavut to the east. Its capital is Yellowknife.
NCI

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Cyprinodon

A genus in the family Cyprinodontidae.
MSH

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podlahy a podlahové krytiny

The surface of a structure upon which one stands or walks.
MSH

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antigeny sacharidové asociované s nádorem

Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.
MSH

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ztuhlost posmrtná

Muscular rigidity which develops in the cadaver usually from 4 to 10 hours after death and lasts 3 or 4 days.
MSH

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leukoencefalopatie progresivní multifokální

An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
MSH

demyelination in various part of the central nervous system, usually secondary to neoplastic disease; JC virus has been recovered from brain tissue.
CSP

A progressive demyelination within the central nervous system associated with reactivation of a latent JC virus infection.
NCI

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nukleární válka

Warfare involving the use of NUCLEAR WEAPONS.
MSH

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cystitida

Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.
MSH

An acute or chronic inflammatory process affecting the bladder.
NCI

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fluor

A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as flouride (FLUORIDES) to prevent dental caries.
MSH

nonmetallic, diatomic gas, symbol F, atomic number 9, atomic weight 18.998, that is a trace element and member of the halogen family.
CSP

An element with atomic symbol F, atomic number 9, and atomic weight 19.0.
NCI

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antisepse

The destruction of germs causing disease.
MSH

prevention of infection by means of agents that inhibit or kill infectious microorganisms on environmental surfaces or a body surface such as skin or mucous membranes.
CSP

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messenger RNA

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3` end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
MSH

RNA sequences that serve as templates for protein synthesis; eukaryotic messenger RNA is synthesized in the nucleus and must be exported to the cytoplasm for translation.
CSP

A type of RNA found in cells. Messenger RNA molecules carry the genetic information needed to make proteins. They carry the information from the DNA in the nucleus of the cell to the cytoplasm where the proteins are made.
NCI

A class of RNA molecule containing protein-coding information in its nucleotide sequence that can be translated into the amino acid sequence of a protein.
NCI

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knihovnické technické služby

Acquisition, organization, and preparation of library materials for use, including selection, weeding, cataloging, classification, and preservation.
MSH

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odborné všeobecné sestry

nurses who are specially trained to assume an expanded role in providing medical care under the supervision of a physician.
CSP

A registered nurse who has additional education and training in how to diagnose and treat disease. NPs are licensed at the state level and certified by national nursing organizations. In cancer care, an NP may manage the primary care of patients and their families, based on a practice agreement with a doctor.
NCI

A registered nurse (RN) with advanced training in diagnosing and treating illness. NPs are master`s degree prepared health experts that focus on helping patients achieve total health and prevent disease. NPs focus on disease prevention, wellness, and patient education. NPs prescribe medications, treat illness, and perform physical examinations. NPs can function independently of physician intervention, but require a practice agreement with a physician. NPs are licensed by a state authority.
NCI

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