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Helianthus

A genus of tall, erect American herbs of the Compositae. The seeds yield oil and are used as food and animal feed; the roots of Helianthus tuberosum (Jerusalem artichoke) are edible.
MSH

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Parvoviridae

unenveloped ssDNA viruses; replication is in the nucleus; one or more cellular functions are necessary for replication.
CSP

A family of very small DNA viruses containing a single molecule of single-stranded DNA and consisting of two subfamilies: PARVOVIRINAE and DENSOVIRINAE. They infect both vertebrates and invertebrates.
MSH

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diethylkarbamazin

An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
MSH

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mitotan

A derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
MSH

An anticancer drug used in treating adrenocortical cancer and ACTH-producing pituitary tumors (Cushing`s disease).
NCI

A synthetic derivative of the insecticide dichlorodiphenyl trichloroethane (DDT) with anti-adrenocorticoid properties. Following its metabolism in the adrenal cortex to a reactive acyl chloride intermediate, mitotane covalently binds to adrenal proteins, specifically inhibiting adrenal cortical hormone production. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39506&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39506&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C664″ NCI Thesaurus)
PDQ

A synthetic derivative of the insecticide dichlorodiphenyl trichloroethane (DDT) with anti-adrenocorticoid properties. Following its metabolism in the adrenal cortex to a reactive acyl chloride intermediate, mitotane covalently binds to adrenal proteins, specifically inhibiting adrenal cortical hormone production. (NCI04)
NCI

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chlornan sodný

It is used as an oxidizing and bleaching agent and as a disinfectant. (From Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

A chlorine compound often used as a disinfectant or a bleaching agent. Sodium hypochlorite in 0.5% w/v solution is called Dakin`s solution, and is used as an antiseptic to clean infected topical wounds.
NCI

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BCG vakcína

An active immunizing agent and a viable avirulent attenuated strain of Mycobacterium tuberculosis, var. bovis, which confers immunity to mycobacterial infections. It is used also in immunotherapy of neoplasms due to its stimulation of antibodies and non-specific immunity.
MSH

active immunizing agent and a viable avirulent attenuated strain of Mycobacterium tuberculosis, var. bovis, which confers immunity to mycobacterial infections; used also in immunotherapy of neoplasms due to its stimulation of antibodies and non-specific immunity.
CSP

A weakened form of the bacterium Mycobacterium bovis (bacillus Calmette-Guerin) that does not cause disease. BCG is used in a solution to stimulate the immune system in the treatment of bladder cancer and as a vaccine to prevent tuberculosis.
NCI

A vaccine containing bacillus Calmette-Guerin (BCG), an attenuated strain of Mycobacterium bovis, with non-specific immunoadjuvant and immunotherapeutic activities. Although the mechanism of its anti-tumor activity is unclear, immunization with BCG vaccine likely activates a Th1 cytokine response that includes the induction of interferon. Vaccination with BCG vaccine may be immunoprotective against infection with Mycobacterium tuberculosis.
NCI

Bacillus Calmette-Guerin vaccine


HL7V3.0

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hematokolpos

A blood-filled VAGINA that is obstructed.
MSH

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vzdělávání pacientů – jako téma

The teaching or training of patients concerning their own health needs.
MSH

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cholestanol

A cholesterol derivative found in human feces, gallstones, eggs, and other biological matter.
MSH

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molekulární biologie

A discipline concerned with studying biological phenomena in terms of the chemical and physical interactions of molecules.
MSH

study of biological processes at the molecular level, including membrane biochemistry, cytoskeleton biochemistry, and structural biology in addition to molecular genetics (see NTs and RTs).
CSP

The study of biology at a molecular level. It chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interrelationship of DNA, RNA and protein synthesis and learning how these interactions are regulated. The field overlaps with other areas of biology, particularly genetics and biochemistry.
NCI

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roztoky

The homogeneous mixtures formed by the mixing of a solid, liquid, or gaseous substance (solute) with a liquid (the solvent), from which the dissolved substances can be recovered by physical processes. (From Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

homogeneous mixture of one or more substances (solutes) dispersed molecularly in a sufficient quantity of dissolving medium (solvent).
CSP

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Belgie

A country in Western Europe, bordering the North Sea, between France and the Netherlands. (NCI)
NCI

A country in Western Europe, bordering the North Sea, between France and the Netherlands. (CIA World Factbook 2002)
NCI

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hemokyanin

protein found in the blood of mollusks and arthropods which imparts its blue color.
CSP

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pedofilie

A sexual disorder occurring in a person 16 years or older and that is recurrent with intense sexually arousing fantasies, sexual urges, or behaviors involving sexual activity with a prepubescent child (generally age 13 or younger). (from APA, DSM-IV, 1994).
MSH

A disorder characterized by recurrent sexual urges, fantasies, or behaviors involving sexual activity with a prepubescent child or children.
NCI

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dimethisteron

A synthetic progestational hormone without significant estrogenic or androgenic properties. It was formerly used as the progestational component in oral sequential contraceptives.
MSH

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monoacylglycerollipasy

An enzyme that catalyzes the hydrolysis of glycerol monoesters of long-chain fatty acids EC 3.1.1.23.
MSH

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sójové boby

An annual legume or the seeds of this plant.
MSH

A product from a plant of Asian origin that produces beans used in many food products. Soybean contains isoflavones (estrogen-like substances) that are being studied for the prevention of cancer, hot flashes that occur with menopause, and osteoporosis (loss of bone density). Soybean in the diet may lower cholesterol levels and reduce the risk of heart disease.
NCI

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benzhydrylové sloučeniny

Compounds which contain the methyl radical substituted with two benzene rings. Permitted are any substituents, but ring fusion to any of the benzene rings is not allowed.
MSH

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hemoperfúze

Removal of toxins or metabolites from the circulation by the passing of blood, within a suitable extracorporeal circuit, over semipermeable microcapsules containing adsorbents (e.g., activated charcoal) or enzymes, other enzyme preparations (e.g., gel-entrapped microsomes, membrane-free enzymes bound to artificial carriers), or other adsorbents (e.g., various resins, albumin-conjugated agarose).
MSH

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Penicillium

A mitosporic Trichocomaceae fungal genus that develops fruiting organs resembling a broom. When identified, teleomorphs include EUPENICILLIUM and TALAROMYCES. Several species (but especially PENICILLIUM CHRYSOGENUM) are sources of the antibiotic penicillin.
MSH

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Dipetalonema

A filarial nematode parasite of mammalian blood with the vector being a tick or small fly.
MSH

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morfin

The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
MSH

principal and most active narcotic alkaloid of opium, having powerful analgesic action and some central stimulant action; abuse leads to dependence.
CSP

An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are involved in controlling different brain functions. In the central nervous and gastrointestinal systems, this agent exhibits widespread effects including analgesia, anxiolysis, euphoria, sedation, respiratory depression, and gastrointestinal system smooth muscle contraction. (NCI04)
NCI

a kind of narcotic pain relieving drug
CHV

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spektrofotometrie infračervená

Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
MSH

a powerful method for analyzing substances whether solids, liquids or gases; deals with transitions between vibrational energy levels in molecules, and is therefore also called vibrational spectroscopy; an IR spectrum is generally displayed as a plot of the energy of the infrared radiation (expressed either in microns or wavenumbers) versus the percent of light transmitted by the compound.
CSP

A spectrometric method that determines the type and concentration of elements or chemicals in a sample, based upon the principle that the atoms in a sample will vibrate or rotate at a specific frequency when exposed to infrared light.
NCI

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bepridil

A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.
MSH

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heparin nízkomolekulární

Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of hemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism.
MSH

Substances comprised of fragmented heparin molecules derived from unfractionated heparin that bind to antithrombin III with a molecular weight ranging from 1000 to 10,000 daltons, which causes changes in property from unfractionated heparin, including decreased protein binding, enhanced bioavailability, decreased platelet interaction, and decreased binding to thrombin.
NCI

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pepstatiny

N-acylated oligopeptides isolated from culture filtrates of Actinomycetes, which act specifically to inhibit acid proteases such as pepsin and renin.
MSH

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katastrofy – předvídání

Procedures outlined for the care of casualties and the maintenance of services in disasters.
MSH

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fluoróza zubů

A chronic endemic form of hypoplasia of the dental enamel caused by drinking water with a high fluorine content during the time of tooth formation, and characterized by defective calcification that gives a white chalky appearance to the enamel, which gradually undergoes brown discoloration. (Jablonski`s Dictionary of Dentistry, 1992, p286)
MSH

A condition that results from excessive fluorine intake during tooth development. Presentation of this disorder can range from white streaks to brown stains and cracks or pits in the tooth enamel.
NCI

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torze semenného provazce

The twisting of the SPERMATIC CORD due to an anatomical abnormality that left the TESTIS mobile and dangling in the SCROTUM. The initial effect of testicular torsion is obstruction of venous return. Depending on the duration and degree of cord rotation, testicular symptoms range from EDEMA to interrupted arterial flow and testicular pain. If blood flow to testis is absent for 4 to 6 h, SPERMATOGENESIS may be permanently lost.
MSH

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betamethason

A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)
MSH

A synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39273&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39273&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C303″ NCI Thesaurus)
PDQ

A synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.
NCI

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