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herpes simplex virus – protein Vmw65

Trans-acting protein that combines with host factors to induce immediate early gene transcription in herpes simplex virus.
MSH

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nukleární válka

Warfare involving the use of NUCLEAR WEAPONS.
MSH

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kreatinin

nitrogen compound in muscle, blood and urine that is the end product of creatine metabolism.
CSP

A compound that is excreted from the body in urine. Creatinine levels are measured to monitor kidney function.
NCI

The breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.
NCI

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myši

Any of numerous species of small rodents belonging to the genus Mus and various related genera of the family Muridae.
NCI

The common name for the genus Mus.
MSH

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messenger RNA

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3` end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
MSH

RNA sequences that serve as templates for protein synthesis; eukaryotic messenger RNA is synthesized in the nucleus and must be exported to the cytoplasm for translation.
CSP

A type of RNA found in cells. Messenger RNA molecules carry the genetic information needed to make proteins. They carry the information from the DNA in the nucleus of the cell to the cytoplasm where the proteins are made.
NCI

A class of RNA molecule containing protein-coding information in its nucleotide sequence that can be translated into the amino acid sequence of a protein.
NCI

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aniontoměniče

High-molecular-weight insoluble polymers that contain functional cationic groups capable of undergoing exchange reactions with anions.
MSH

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hexobarbital

A barbiturate that is effective as a hypnotic and sedative.
MSH

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odborné všeobecné sestry

nurses who are specially trained to assume an expanded role in providing medical care under the supervision of a physician.
CSP

A registered nurse who has additional education and training in how to diagnose and treat disease. NPs are licensed at the state level and certified by national nursing organizations. In cancer care, an NP may manage the primary care of patients and their families, based on a practice agreement with a doctor.
NCI

A registered nurse (RN) with advanced training in diagnosing and treating illness. NPs are master`s degree prepared health experts that focus on helping patients achieve total health and prevent disease. NPs focus on disease prevention, wellness, and patient education. NPs prescribe medications, treat illness, and perform physical examinations. NPs can function independently of physician intervention, but require a practice agreement with a physician. NPs are licensed by a state authority.
NCI

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krotonový olej

Viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae). It is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality.
MSH

viscous, nauseating oil obtained from the shrub Croton tiglium (Euphorbaceae); a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy; causes skin cancer; was formerly used as an emetic and cathartic with frequent mortality.
CSP

A yellow to brown colored, thick, foul smelling, very toxic oil obtained from the seeds of a tropical plant, Croton Tiglium. Croton oil was used as a drastic purgative agent, but is now mostly used as a standard irritant in pharmacological research. Exposure to this substance causes severe skin irritation and affects the small intestine leading to severe diarrhea. Croton oil is a possible human carcinogen. (NCI05)
NCI

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mutagenita – testy

Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests.
MSH

tests of chemical substances and physical agents for mutagenic potential, including cell culture, microbial, insect, mammalian cell, and whole animal tests.
CSP

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RNA transferová Trp

A transfer RNA which is specific for carrying tryptophan to sites on the ribosomes in preparation for protein synthesis.
MSH

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přední komora oční

The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)
MSH

space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil.
CSP

The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109)
NCI

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kyčel – protézy

Replacement for a hip joint.
MSH

artificial substitute, constructed of either synthetic or biological material, which is used to partially or totally replace or repair injured or diseased hips.
CSP

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výživa – hodnocení

Evaluation and measurement of nutritional variables in order to assess the level of nutrition or the NUTRITIONAL STATUS of the individual. NUTRITION SURVEYS may be used in making the assessment.
MSH

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kulturní charakteristiky

Those aspects or characteristics which identify a culture.
MSH

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mykózy

disease caused by a fungus.
CSP

If you have ever had athlete`s foot or a yeast infection, you can blame a fungus. A fungus is actually a primitive vegetable. Mushrooms, mold and mildew are examples. Fungi live in air, in soil, on plants and in water. Some live in the human body. Only about half of all types of fungi are harmful.

Some fungi reproduce through tiny spores in the air. You can inhale the spores or they can land on you. As a result, fungal infections often start in the lungs or on the skin. You are more likely to get a fungal infection if you have a weakened immune system or take antibiotics.

Fungi can be difficult to kill. For skin and nail infections, you can apply medicine directly to the infected area. Oral antifungal medicines are also available for serious infections.

NIH: National Institute of Allergy and Infectious Diseases


MEDLINEPLUS

An infection caused by a fungus.
NCI

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virus Ross River

species of Alphavirus associated with epidemic exanthema and polyarthritis in Australia.
CSP

A species of ALPHAVIRUS associated with epidemic EXANTHEMA and polyarthritis in Australia.
MSH

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aurodox

Antibiotic obtained from a Streptomyces variant considered as possibly effective against Streptococcus pyogenes infections. It may promote growth in poultry.
MSH

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histokompatibilita – antigeny třídy II

Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.
MSH

large transmembrane non-covalently linked glycoproteins; class II antigens in humans are called HLA-D antigens and coded on a gene on chromosome 6; in mice two genes named IA and iE on chromosome 17 code for the H-2 antigens; class II antigens are found on B-lymphocytes, macrophages, epidermal cells and sperm and are thought to mediate the competence of and cellular cooperation in the immune response.
CSP

One of a group of proteins found on the surface of white blood cells and other cells that play an important part in the body`s immune response to foreign substances. These antigens vary from person to person, and human leukocyte antigen tests are done before organ transplantation to find out if tissues match between a donor and a recipient.
NCI

MHC Class-II Proteins are non-covalently linked polymorphic alpha/beta transmembrane glycoproteins. The immunological function of MHC Class-II proteins is to bind and present antigenic peptides on the surfaces of cells for recognition by the antigen-specific T cell receptors of lymphocytes. These proteins plays an important role in the mediation of immune response.
NCI

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okcipitální lalok

Posterior part of the cerebral hemisphere.
MSH

Occipital lobe is the one of five lobes of the cerebral hemisphere which occupies the posterior-most portion of the hemisphere. Anteriorly, it shares an arbitrary border with the parietal lobe and temporal lobe. Medially, it is bounded by the longitudinal cerebral fissure.
FMA

The posterior part of the cerebral hemisphere. (MeSH)
NCI

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proteinkinasy závislé na cyklickém AMP

A group of enzymes that are dependent on CYCLIC AMP and catalyze the phosphorylation of SERINE or THREONINE residues on proteins. Included under this category are two cyclic-AMP-dependent protein kinase subtypes, each of which is defined by its subunit composition.
MSH

nonEC; enzyme is stimulated by intracellular cyclic AMP, and therefore links that important second messenger system to the equally important protein phosphorylation cascade for transducing biological signals.
CSP

Most cellular effects of cAMP are mediated through PKA by serine or threonine phosphorylation of target proteins. Human Protein Kinase A (cAMP Ser/Thr Protein Kinase Family) is an inactive tetrameric cytoplasmic holoenzyme composed of homo- or heterodimeric regulatory subunits associated with two catalytic subunits. cAMP causes dissociation of inactive holoenzyme into a cAMP-bound dimer of regulatory subunits and two free monomeric catalytic subunits that phosphorylate many cytoplasmic and nuclear substrates. In human, regulatory PRKAR1A, PRKAR1B, PRKAR2A, and PRKAR2B subunits and catalytic PRKACA, PRKACB, and PRKACG subunits have been identified. (NCI)
NCI

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syndromy myofasciální bolesti

Muscular pain in numerous body regions that can be reproduced by pressure on TRIGGER POINTS, localized hardenings in skeletal muscle tissue. Pain is referred to a location distant from the trigger points. A prime example is the TEMPOROMANDIBULAR JOINT DYSFUNCTION SYNDROME.
MSH

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ruthenium

A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.
MSH

hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44; used as a catalyst and hardener for platinum and palladium.
CSP

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antidepresiva

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
MSH

mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
CSP

A drug used to treat depression.
NCI

Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Medicines sometimes cause unwanted side effects. For example, when you first start your antidepressant you may feel tired, have trouble sleeping or feel sick to your stomach. The side effects usually go away after a short time. Tell your doctor if you have any side effects. You should also let your doctor know if you take any other medicines, vitamins or herbal supplements.

It is important to keep taking your medicines, even if you feel better. Do not stop taking your medicines without talking to your doctor. You often need to stop antidepressants gradually.

NIH: National Institute of Mental Health


MEDLINEPLUS

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several monoamine oxidase inhibitors are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents also appear to act through brain catecholamine systems. A third group is a diverse group of drugs including some that act specifically on serotonergic systems. (MeSH)
NCI

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HIV-2

An HIV species related to HIV-1 but carrying different antigenic components and with differing nucleic acid composition. It shares serologic reactivity and sequence homology with the simian Lentivirus SIMIAN IMMUNODEFICIENCY VIRUS and infects only T4-lymphocytes expressing the CD4 phenotypic marker.
MSH

HIV species related to HIV1 but carrying different antigenic components and with differing nucleic acid composition; shares serologic reactivity and sequence homology with the simian Lentivirus SIV and infects only T4 lymphocytes expressing the CD4 phenotypic marker.
CSP

An HIV species related to HIV-1 but carrying different antigenic components and with differing nucleic acid composition. It shares serologic reactivity and sequence homology with the simian Lentivirus SIV and infects only T4-lymphocytes expressing the CD4 phenotypic marker. (from MeSH)
NCI

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odontoblasty

connective tissue cell which deposits dentin and forms the outer surface of the dental pulp adjacent to the dentin.
CSP

A cell derived from a preodontoblast that secretes predentin. Each odontoblast has a cytoplasmic extension, an odontoblastic process that traverses the thickness of the dentin and helps to maintain the dentin.
NCI

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Cyprinodon

A genus in the family Cyprinodontidae.
MSH

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myxom

A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mesenchymal tissue. It occurs frequently intramuscularly where it may be mistaken for a sarcoma. It appears also in the jaws and the skin. (From Stedman, 25th ed)
MSH

A benign soft tissue neoplasm characterized by the presence of spindle and stellate cells, lobulated growth pattern, and myxoid stroma formation.
NCI

A benign soft tissue neoplasm characterized by the presence of neoplastic spindle and stellate cells in a myxoid stroma.
NCI

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salicylany

The salts, esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.
MSH

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antigeny sacharidové asociované s nádorem

Carbohydrate antigens expressed by malignant tissue. They are useful as tumor markers and are measured in the serum by means of a radioimmunoassay employing monoclonal antibodies.
MSH

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