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guanyloribonukleasa

An enzyme catalyzing the endonucleolytic cleavage of RNA at the 3`-position of a guanylate residue. EC 3.1.27.3.
MSH

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C-peptid

The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.
MSH

A substance made by the pancreas. C-peptide and insulin are both part of a larger molecule that gets split apart before being released into the blood. Abnormal blood levels of C-peptide may occur in certain diseases, such as diabetes or cancer.
NCI

C peptide (31 aa, ~3 kDa) is encoded by the human INS gene. This protein is involved in both signal transduction and the modulation of blood flow.
NCI

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faryngální svaly

The muscles of the PHARYNX are voluntary muscles arranged in two layers. The external circular layer consists of three constrictors (superior, middle, and inferior). The internal longitudinal layer consists of the palatopharyngeus, the salpingopharyngeus, and the stylopharyngeus. During swallowing, the outer layer constricts the pharyngeal wall and the inner layer elevates pharynx and LARYNX.
MSH

The muscles of the pharynx, the inferior, middle and superior constrictors, salpingopharyngeus, and stylopharyngeus. (MeSH)
NCI

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methomyl

A carbamate insecticide with anticholinesterase activity.
MSH

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enalaprilát

The active metabolite of ENALAPRIL and a potent intravenously administered angiotensin-converting enzyme inhibitor. It is an effective agent for the treatment of essential hypertension and has beneficial hemodynamic effects in heart failure. The drug produces renal vasodilation with an increase in sodium excretion.
MSH

The active metabolite of the pro-drug enalapril, a dicarboxylate-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Enalaprilat prevents the conversion of angiotensin I into angiotensin II by inhibiting ACE, thereby leading to decreased vasopressor activity and resulting in vasodilation. This agent also decreases aldosterone secretion by the adrenal cortex, which leads to an increase in natriuresis.
NCI

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steroidhydroxylasy

Cytochrome P-450 monooxygenases (MIXED FUNCTION OXYGENASES) that are important in steroid biosynthesis and metabolism.
MSH

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Haemophilus

genus of Pasteurellaceae that consists of several species occurring in animals and humans; organisms are described as gram negative, facultatively anaerobic, coccobacillus or rod shaped, and nonmotile.
CSP

A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile.
MSH

A genus of Gram-negative, pleomorphic, coccobacilli bacteria belonging to the Proteobacteria phylum.
NCI

a kind of bacteria
CHV

Any bacteria that is not assigned to the species level but can be assigned to the Haemophilus genus level.
NCI

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chlorid vápenatý

A salt used to replenish calcium levels, as an acid-producing diuretic, and as an antidote for magnesium poisoning.
MSH

A crystalline, white substance, soluble in water, Calcium Chloride is the chloride salt of calcium, a bivalent metallic element with many crucial biological roles. Calcium is a major constituent of the skeleton but plays many roles as an intracellular and plasma ion as well. In medicine, calcium chloride is also used as a 10% solution in injection, for calcium replenishment. (NCI04)
NCI

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fenprokumon

Coumarin derivative that acts as a long acting oral anticoagulant.
MSH

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methylhydraziny

Hydrazines substituted by one or more methyl groups in any position.
MSH

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endarteritida

Inflammation of the inner endothelial lining (TUNICA INTIMA) of an artery.
MSH

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ústní a čelistní systém

The mouth, teeth, jaws, pharynx, and related structures as they relate to mastication, deglutition, and speech.
MSH

Functional system which consists of structures involved in speech and in the receiving, mastication, and deglutition of food.
FMA

The mouth, teeth, jaws, pharynx, and related structures as they relate to mastication, deglutition, and speech. (MeSH)
NCI

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Dwerghamsters, Chinese

Originating in the deserts of northern China and Mongolia and kept in captivity since 1919, these hamsters exhibit a whitish/grey/brown coat color with a black stripe down the spine, and have a life span of two to three years. The Chinese hamster has a relatively long thin body and tail in comparison to other hamster breeds and is crepuscular year round in captivity. Of note, Chinese hamster ovary cell lines are highly transfectable and are used in a variety of pre-clinical research applications.
NCI

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kalmodulin

A heat-stable, low-molecular-weight activator protein found mainly in the brain and heart. The binding of calcium ions to this protein allows this protein to bind to cyclic nucleotide phosphodiesterases and to adenyl cyclase with subsequent activation. Thereby this protein modulates cyclic AMP and cyclic GMP levels.
MSH

intracellular protein that mediates the calcium dependence of many enzymes and cell functions.
CSP

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filatelie

Study of stamps or postal markings. It usually refers to the design and commemorative aspects of the stamp.
MSH

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HILEROKOARTEKO ODOLJARIOA ETA ZIKLOKO BESTE ZENBAIT NAHASTE

Abnormal uterine bleeding that is not related to MENSTRUATION, usually in females without regular MENSTRUAL CYCLE. The irregular and unpredictable bleeding usually comes from a dysfunctional ENDOMETRIUM.
MSH

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endoribonukleasy

A family of enzymes that catalyze the endonucleolytic cleavage of RNA. It includes EC 3.1.26.-, EC 3.1.27.-, EC 3.1.30.-, and EC 3.1.31.-.
MSH

A hydrolase enzyme which makes oligonucleotides and polynucleotides by hydrolysing the interior bonds of ribonucleotides. (On-line Medical Dictionary)
NCI

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psychický stres

Stress wherein emotional factors predominate.
MSH

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hlava

Body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the skull, it is partially surrounded by skin of head. Examples: There is only one head.
UWDA

upper, anterior, or proximal extremity of a structure or body, especially that part of an organism which contains the brain and the organs of special sense.
CSP

Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the skull, it is partially surrounded by skin of head. Examples: There is only one head.
FMA

The anterior and superior part of a human or animal bearing the mouth, the brain and sensory organs.
NCI

The anterior and superior part of a human bearing the mouth, the brain and sensory organs.
NCI

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kandidóza chronická mukokutánní

A clinical syndrome characterized by development, usually in infancy or childhood, of a chronic, often widespread candidiasis of skin, nails, and mucous membranes. It may be secondary to one of the immunodeficiency syndromes, inherited as an autosomal recessive trait, or associated with defects in cell-mediated immunity, endocrine disorders, dental stomatitis, or malignancy.
MSH

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fosfáty

Inorganic salts of phosphoric acid.
MSH

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mikrocirkulace

The circulation of the BLOOD through the MICROVASCULAR NETWORK.
MSH

flow of blood in the entire system of finer vessels or microvasculature of the body.
CSP

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enteritida přenosná krocanů

An acute, highly contagious virus disease of turkeys characterized by chilling, anorexia, decreased water intake, diarrhea, dehydration and weight loss. The infectious agent is a CORONAVIRUS.
MSH

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koktavost

A disturbance in the normal fluency and time patterning of speech that is inappropriate for the individual`s age. This disturbance is characterized by frequent repetitions or prolongations of sounds or syllables. Various other types of speech dysfluencies may also be involved including interjections, broken words, audible or silent blocking, circumlocutions, words produced with an excess of physical tension, and monosyllabic whole word repetitions. Stuttering may occur as a developmental condition in childhood or as an acquired disorder which may be associated with BRAIN INFARCTIONS and other BRAIN DISEASES. (From DSM-IV, 1994)
MSH

disorder in which speech is involuntarily interrupted by hesitations, repetitions, and spasms of the muscles involved in breathing or vocalization.
CSP

Stuttering is a problem that affects the flow of your speech. If you stutter, you may

  • Make certain words sound longer than they should be
  • Find it hard to start a new word
  • Repeat words or parts of words
  • Get tense when you try to speak. You may blink your eyes rapidly, or your lips and jaw may tremble as you struggle to get the words out

Stuttering can affect anyone. However, it is most common in young children who are still learning to speak. Boys are three times more likely to stutter than girls. Most children stop stuttering as they grow older. Less than 1 percent of adults stutter.

Scientists don`t fully understand why some people stutter. The problem seems to run in families. There is no cure, but stuttering therapy for young children can keep it from becoming a lifelong problem.

NIH: National Institute on Deafness and Other Communication Disorders


MEDLINEPLUS

A speech disorder characterized by frequent sound or syllable repetitions, sound prolongations, or other dysfluencies that are inappropriate for the individual`s age.
NCI

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zdravotnické plánování – směrnice

Recommendations for directing health planning functions and policies. These may be mandated by PL93-641 and issued by the Department of Health and Human Services for use by state and local planning agencies.
MSH

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tobolky

Hard or soft soluble containers used for the oral administration of medicine.
MSH

A solid pharmaceutical dosage form that contains medicinal agent within either a hard or soft soluble container or shell, usually used for the oral administration of medicine. The shells are made of a suitable form of gelatin or other substance. (NCI)
NCI

A solid contained within either a hard or soft soluble shell, usually prepared from gelatin.
NCI

A form for medicine that is taken by mouth. It usually has a shell made of gelatin with the medicine inside.
NCI

A drug packaging type usually in a cylindrical shape with rounded ends. Capsule shells may be made from gelatin, starch, or cellulose, or other suitable materials, may be soft or hard, and are filled with solid or liquid drug products.
NCI

A solid dosage form in which the drug is enclosed within either a hard or soft soluble container or “shell” made from a suitable form of gelatin.


HL7V3.0

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fosfolipasy A

Phospholipases that hydrolyze one of the acyl groups of phosphoglycerides or glycerophosphatidates.
MSH

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Microsomal Epoxide Hydrolase

Expression of microsomal epoxide hydrolase (mEH), a carcinogen-activating enzyme, in primary breast tumors may predict poor response to tamoxifen treatment. (from J Clin Oncol 2001;19:3-9 via Medscape)
NCI

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enzymy – indukce

An increase in the rate of synthesis of an enzyme due to the presence of an inducer which acts to derepress the gene responsible for enzyme synthesis.
MSH

Enzyme Induction involves initiation of function of a biological molecule that possesses catalytic activity.
NCI

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substantia gelatinosa

Gelatinous-appearing material in the dorsal horn of the spinal cord, consisting chiefly of Golgi type II neurons and some larger nerve cells.
MSH

Gelatinous-appearing material in the dorsal horn of the spinal cord, consisting chiefly of Golgi type II neurons and some larger nerve cells. (MeSH)
NCI

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