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hutnictví

The science, art, or technology dealing with processes involved in the separation of metals from their ores, the technique of making or compounding the alloys, the techniques of working or heat-treating metals, and the mining of metals. It includes industrial metallurgy as well as metallurgical techniques employed in the preparation and working of metals used in dentistry, with special reference to orthodontic and prosthodontic appliances. (From Jablonski, Dictionary of Dentistry, 1992, p494)
MSH

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GTP-fosfohydrolasy

nonEC; family of high energy phosphate hydrolases; unlike ATPases, which are mainly involved in bioenergetics, GTPases are mainly involved in biological signal transduction.
CSP

Enzymes that hydrolyze GTP to GDP. EC 3.6.1.-.
MSH

Proteins that hydrolyze guanine triphosphate to yield guanine diphosphate. This is a class of proteins that belongs to a family of high energy phosphate hydrolases. Members of this family play major roles in biological signal transduction pathways.
NCI

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obory chirurgické

Various branches of surgical practice limited to specialized areas.
MSH

The branch of medical science that treats disease or injury by operative procedures.
NCI

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pentoliniumtartrát

A nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.
MSH

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chromozómy lidské, pár 13

A specific pair of GROUP D CHROMOSOMES of the human chromosome classification.
MSH

The designation for each member of the thirteenth largest human autosomal chromosome pair. Chromosome 13 spans about 113 million base pairs and represents between 3.5 and 4% of the total DNA in normal diploid cells.
NCI

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methansulfonáty

Organic salts or esters of methanesulfonic acid.
MSH

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Caviidae

Taxonomic family which includes Guinea pigs, wild cavies, and the capybara.
NCI

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řeč ezofageální

A method of speech used after laryngectomy, with sound produced by vibration of the column of air in the esophagus against the contracting cricopharyngeal sphincter. (Dorland, 27th ed)
MSH

Speech produced by trapping air in the esophagus and forcing it out again. It is used after removal of a person`s larynx (voice box).
NCI

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peptidyltransferasy

Acyltransferases that use AMINO ACYL TRNA as the amino acid donor in formation of a peptide bond. There are ribosomal and non-ribosomal peptidyltransferases.
MSH

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chymotrypsin

A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.
MSH

serine endopeptidase secreted by the pancreas as its zymogen, chymotrypsinogen, and carried in the pancreatic juice to the duodenum where it is activated by trypsin.
CSP

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methoxyfluran

An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with NITROUS OXIDE to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180)
MSH

highly potent inhalation anesthetic used primarily to produce analgesia during the first stage of labor; use limited by dose related nephrotoxicity.
CSP

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vláskové buňky vnitřní

Auditory sensory cells of organ of Corti, usually placed in one row medially to the core of spongy bone (the modiolus). Inner hair cells are in fewer numbers than the OUTER AUDITORY HAIR CELLS, and their STEREOCILIA are approximately twice as thick as those of the outer hair cells.
MSH

A cell situated on the inner most layer of the basilar membrane of the cochlea. Each cell has multiple, sensitive strands called stereocilia. In the resting state the stereocilia are leaning on each other in a conical bundle and touch the tectorial membrane. When the cochlea moves in response to sound, a slight shearing force occurs between the basilar and tectorial membranes, the stereocilia bend and send electrical impulses to the brain via the eighth cranial nerve.
NCI

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sférocytóza dědičná

A familial congenital hemolytic anemia characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. The erythrocytes have increased osmotic fragility and are abnormally permeable to sodium ions.
MSH

autosomal dominant trait marked by splenomegaly, jaundice, and fragile, spheroid erythrocytes which are prematurely cleared by the spleen; anemia is usually mild; treatment is splenectomy.
CSP

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perikardektomie

Surgical excision (total or partial) of a portion of the pericardium. Pericardiotomy refers to incision of the pericardium.
MSH

Surgical removal of all or part of the pericardium.
NCI

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citrát-(si)-synthasa

the first enzyme of the Krebs` cycle transfers the 2-carbon unit from acetyl coA to oxaloacetate, forming citrate.
CSP

Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.
MSH

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nordefrin

A norepinephrine derivative used as a vasoconstrictor agent.
MSH

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nemoc rukou, nohou a úst

A mild, highly infectious viral disease of children, characterized by vesicular lesions in the mouth and on the hands and feet. It is caused by coxsackieviruses A.
MSH

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ganglion spirale

The sensory ganglion of the COCHLEAR NERVE. The cells of the spiral ganglion send fibers peripherally to the cochlear hair cells and centrally to the COCHLEAR NUCLEI of the BRAIN STEM.
MSH

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periferní nervový systém – nádory

Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)
MSH

A benign or malignant neoplasm arising from a peripheral nerve or the perineural sheaths.
NCI

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klindamycin

An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.
MSH

an antibacterial drug
CHV

A semisynthetic broad spectrum antibiotic produced by chemical modification of the parent compound lincomycin. Clindamycin dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. (NCI04)
NCI

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Mus musculus

the scientific name of the common house mouse; for inbred and mutant strain mice used in research, use LABORATORY MOUSE or narrower terms.
CSP

The common house mouse, often used as an experimental organism.
NCI

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nemocenské dávky pracujícím – plány

Health insurance plans for employees, and generally including their dependents, usually on a cost-sharing basis with the employer paying a percentage of the premium.
MSH

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spondylolistéza

Forward displacement of a superior vertebral body over the vertebral body below.
MSH

forward displacement of one vertebra over another
CHV

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rozvoj osobnosti

Growth of habitual patterns of behavior in childhood and adolescence.
MSH

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klopidol

A very effective anticoccidial agent used in poultry.
MSH

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mikrofilamentové proteiny

Monomeric subunits of primarily globular ACTIN and found in the cytoplasmic matrix of almost all cells. They are often associated with microtubules and may play a role in cytoskeletal function and/or mediate movement of the cell or the organelles within the cell.
MSH

Structurally complex proteins that are comprised of microfilaments, which are necessary components of the cellular cytoskeleton for motility and shape. Microfilaments physically associate with microtubules to play a structural role in cytoskeleton integrity.
NCI

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zdravotnictví – zdroje

Available manpower, facilities, revenue, equipment, and supplies to produce requisite health care and services.
MSH

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stanozolol

A synthetic steroid that has anabolic and androgenic properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1194)
MSH

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bakteriofág phi X 174

The type species of the genus MICROVIRUS. A prototype of the small virulent DNA coliphages, it is composed of a single strand of supercoiled circular DNA, which on infection, is converted to a double-stranded replicative form by a host enzyme.
MSH

Microvisus type species; circular (+)-sense ssDNA; causes lysis of enterobacteria within 25-30 minutes of entry.
CSP

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kokain

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
MSH

alkaloid ester extracted from the leaves of plants including coca; has powerful central nervous system effects similar to the amphetamines and is a drug of abuse; acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake; it is also a local anesthetic and vasoconstrictor and is clinically used for that purpose.
CSP

Cocaine is a powerful drug that stimulates the brain. People who use it can form a strong addiction. They may have to use more and more of the drug to get high. It`s sold on the street as a fine, white powder. There are two forms of cocaine: hydrochloride salt and freebase. The salt dissolves in water. People can take it in a vein or in the nose. The freebase form can be smoked. Crack is the street name of a smokable form of cocaine.

No matter how cocaine is taken, it is dangerous. Some of the most common serious problems include

  • Heart problems, including heart attacks
  • Respiratory effects, including respiratory failure
  • Nervous system problems, including strokes
  • Digestive problems

Any of these can be fatal. Using cocaine with alcohol is a common cause of drug-related death.

NIH: National Institute on Drug Abuse


MEDLINEPLUS

A tropane alkaloid with central nervous systems (CNS) stimulating and local anesthetic activity. Cocaine binds to the dopamine, serotonin, and norepinephrine transport proteins and inhibits the re-uptake of dopamine, serotonin, and norepinephrine into pre-synaptic neurons. This leads to an accumulation of the respective neurotransmitters in the synaptic cleft and may result in increased postsynaptic receptor activation. The mechanism of action through which cocaine exerts its local anesthetic effects is by binding to and blocking the voltage-gated sodium channels in the neuronal cell membrane. By stabilizing neuronal membranes, cocaine inhibits the initiation and conduction of nerve impulses and produces a reversible loss of sensation.
NCI

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