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digitonin

A glycoside obtained from Digitalis purpurea; the aglycone is digitogenin which is bound to five sugars. Digitonin solubilizes lipids, especially in membranes and is used as a tool in cellular biochemistry, and reagent for precipitating cholesterol. It has no cardiac effects.
MSH

steroid saponin (soapy glucoside) derived from digitalis, used as a cholesterol indicator (the complex precipitates).
CSP

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analýza metodou nejmenších čtverců

A principle of estimation in which the estimates of a set of parameters in a statistical model are those quantities minimizing the sum of squared differences between the observed values of a dependent variable and the values predicted by the model.
MSH

A popular criterion used for a cost function, namely minimizing the sum of the squares of the differences between the data points and the analytical function (often a straight line) desired as a best fit. (Dr. Joseph A. Thie)
NCI

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behaviorální terapie

The application of modern theories of learning and conditioning in the treatment of behavior disorders.
MSH

specific techniques which use classical or operant conditioning, or perceptual learning, to change behavior, especially to extinguish socially undesirable behavior, attitudes, or phobias.
CSP

therapeutic approach in which the focus is on the patient`s observable behavior, rather than on conflicts and unconscious processes presumed to underlie his maladaptive behavior; accomplished through systematic manipulation of the environmental and behavioral variables related to the specific behavior to be modified; operant conditioning, systematic desensitization, token economy, aversive control, flooding, and implosion are examples of techniques that may be used in behavior therapy.
CSP

A technique used to help people change the way they react to certain triggers in the environment that cause a negative reaction. In cancer treatment, behavior modification may be used to help patients who have become nauseous during previous cancer treatments cope with nausea they feel when they enter the therapy room to begin a new round of treatment.
NCI

The use of operant conditioning, including rewards and punishments, in helping a person create an atmosphere where he or she does not contribute to painful stimuli.
NCI

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Valsalvův sinus

The dilatation of the aortic wall behind each of the cusps of the aortic valve.
MSH

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fétomaternální transfúze

Transplacental passage of fetal blood into the circulation of the maternal organism. (Dorland, 27th ed)
MSH

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horečka pappataci

Influenza-like febrile viral disease caused by several members of the BUNYAVIRIDAE family and transmitted mostly by the bloodsucking sandfly Phlebotomus papatasii.
MSH

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dilatace

The act of dilating.
MSH

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Leighova nemoc

A group of metabolic disorders primarily of infancy characterized by the subacute onset of psychomotor retardation, hypotonia, ataxia, weakness, vision loss, eye movement abnormalities, seizures, dysphagia, and lactic acidosis. Pathological features include spongy degeneration of the neuropile of the basal ganglia, thalamus, brain stem, and spinal cord. Patterns of inheritance include X-linked recessive, autosomal recessive, and mitochondrial. Leigh disease has been associated with mutations in genes for the PYRUVATE DEHYDROGENASE COMPLEX; CYTOCHROME-C OXIDASE; ATP synthase subunit 6; and subunits of mitochondrial complex I. (From Menkes, Textbook of Child Neurology, 5th ed, p850).
MSH

An inherited disorder affecting the nervous system, caused by genetic mutations in the mitochondrial DNA or deficiency of pyruvate dehydrogenase. Signs and symptoms appear in infancy and include loss of the motor abilities, poor sucking abilities, irritability, lack of muscle tone, and seizures.
NCI

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benzalkoniové sloučeniny

A mixture of alkylbenzyldimethylammonium compounds. It is a bactericidal quaternary ammonium detergent used topically in medicaments, deodorants, mouthwashes, as a surgical antiseptic, and as a as preservative and emulsifier in drugs and cosmetics.
MSH

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Akrochordon

benign skin tumor
CHV

A polypoid lesion composed of fibrous tissue and epithelium. Representative examples include skin tag, anal fibroepithelial polyp, and gingival fibroepithelial polyp.
NCI

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fibrózní dysplazie monostotická

FIBROUS DYSPLASIA OF BONE involving only one bone.
MSH

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parametritida

Inflammation of the parametrium, the connective tissue of the pelvic floor, extending from the subserous coat of the uterus laterally between the layers of the BROAD LIGAMENT.
MSH

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dinoprost

A naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. Due to its vasocontractile properties, the compound has a variety of other biological actions.
MSH

A synthetic analogue of the naturally occurring prostaglandin F2 alpha. Prostaglandin F2 alpha stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum. (NCI04)
NCI

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leprosaria

Residential treatment centers for individuals with leprosy.
MSH

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benzfetamin

A sympathomimetic agent with properties similar to DEXTROAMPHETAMINE. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
MSH

A sympathomimetic amine related to the synthetic agent amphetamine with central nervous system (CNS) stimulating and anorexic properties. Benzphetamine stimulates the release of certain catecholamines, particularly noradrenaline and dopamine, from nerve terminals in the brain and inhibits their uptake. The increase in synaptic concentrations of these catecholamines causes behavioral changes including euphoria, an increase in mental alertness and excitement, and suppresses appetite.
NCI

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hlemýždi

Marine, freshwater, or terrestrial mollusks of the class Gastropoda. Most have an enclosing spiral shell, and several genera harbor parasites pathogenic to man.
MSH

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požáry

Whether a fire happens in your home or in the wild, it can be very dangerous. Fire spreads quickly. There is no time to gather valuables or make a phone call. In just two minutes, a fire can become life-threatening. In five minutes, a home can be engulfed in flames.

Heat and smoke from fire can be more dangerous than the flames. Inhaling the super-hot air can burn your lungs. Fire produces poisonous gases that make you disoriented and drowsy. Instead of being awakened by a fire, you may fall into a deeper sleep. You can suffocate or be burned.

Preventing fires is an important part of fire safety. Although there are no guarantees of safety during a fire, you can take actions to protect yourself. You should have a disaster plan. Being prepared can help reduce fear, anxiety and losses.

Federal Emergency Management Agency


MEDLINEPLUS

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parathormon

polypeptide hormone secreted by the parathyroid glands which maintains intracellular calcium levels in the body; parathyroid hormone increases intracellular calcium by promoting the release of calcium from bone, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.
CSP

Encoded by human PTH Gene (Parathyroid Hormone Family), secreted (parathyroid cells) 115-aa 13-kDa (precursor) Parathyroid Hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing renal excretion. PTH defects cause familial isolated hypoparathyroidism. (NCI) Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=489119&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=489119&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C41027″ NCI Thesaurus)
PDQ

A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.
MSH

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dipyron

A drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE. Because of the risk of serious adverse effects its use is justified only in serious situations where no alternative is available or suitable. (From Martindale, The Extra Pharmacopoeia, 30th ed, p13)
MSH

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leukémie eozinofilní akutní

A rare acute myeloid leukemia characterized by abnormal EOSINOPHILS in the bone marrow.
MSH

A poorly defined concept which at best is described as an extremely rare entity, possibly related to various subtypes of acute myeloid leukemia with abnormal eosinophils. (WHO, 2001)
NCI

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beta-globiny

Members of the beta-globin family. In humans, they are encoded in a gene cluster on CHROMOSOME 11. They include epsilon-globin, gamma-globin, delta-globin and beta-globin. There is also a pseudogene of beta (theta-beta) in the gene cluster. Adult HEMOGLOBIN is comprised of two ALPHA-GLOBIN chains and two beta-globin chains.
MSH

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sociální plánování

Interactional process combining investigation, discussion, and agreement by a number of people in the preparation and carrying out of a program to ameliorate conditions of need or social pathology in the community. It usually involves the action of a formal political, legal, or recognized voluntary body.
MSH

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Siphonaptera

fleas are small and wingless; usually are ectoparasites on birds or mammals; adults feed on the blood of the host and lay eggs in the host or the dirt of the host nest.
CSP

An order of parasitic, blood-sucking, wingless INSECTS with the common name of fleas.
MSH

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partenogeneze

A unisexual reproduction without the fusion of a male and a female gamete (FERTILIZATION). In parthenogenesis, an individual is formed from an unfertilized OVUM that did not complete MEIOSIS. Parthenogenesis occurs in nature and can be artificially induced.
MSH

modified form of sexual reproduction by the development of a gamete without fertilization; occurs in some plants and invertebrates, especially arthropods, and in certain lizards; may occur naturally or be induced by chemical, thermal, or mechanical stimulation.
CSP

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disopyramid

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
MSH

class I antiarrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane stabilizing agent) with a depressant action on the heart similar to that of guanidine; it also possesses some anticholinergic and local anesthetic properties.
CSP

A class IA anti-arrhythmic agent with cardiac depressant property. Disopyramide blocks the fast sodium channel in normal cardiac cell membranes within atrial and ventricular tissues. This slows the rate and amplitude of phase 0 depolarization and thus prolongs the duration of the action potential, thereby reducing cell excitability and conduction velocity. Further, disopyramide directly decreases the rate of diastolic (phase 4) depolarization in cells with normal or augmented automaticity. Disopyramide also blocks potassium channel and results in prolonged QT interval, thus increases the effective refractory period. This agent also possesses anticholinergic property.
NCI

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leukocyty – poruchy

disordered formation of various types of leukocytes or an abnormal accumulation or deficiency of these cells.
CSP

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Bifidobacterium

A rod-shaped, gram-positive, non-acid-fast, non-spore-forming, non-motile bacterium that is a genus of the family Bifidobacteriaceae, order Bifidobacteriales, class ACTINOBACTERIA. It inhabits the intestines and feces of humans as well as the human vagina.
MSH

Any bacteria that is not assigned to the species level but can be assigned to the Bifidobacterium genus level.
NCI

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Cloxacillin Sodium

The sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis.
NCI

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fluoreskamin

A nonfluorescent reagent for the detection of primary amines, peptides and proteins. The reaction products are highly fluorescent.
MSH

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patologie chirurgická

A field of anatomical pathology in which living tissue is surgically removed for the purpose of diagnosis and treatment.
MSH

A field of anatomical pathology in which tissue or cells removed from a living organism are macroscopically and microscopically reviewed for the purpose of disease diagnosis.
NCI

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