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karyometrie

Microscopic study of the spacial distribution pattern of CHROMATIN in CELL NUCLEI and CELL NUCLEOLI.
MSH

Video-microscopy procedure for the analysis of the nuclear chromatin organization status in neoplastic lesions and the detection of nuclear subpopulations on hematoxylin-eosin stained sections.
NCI

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exocytóza

cellular release of material within membrane-limited vesicles by fusion of the vesicles with the cell membrane.
CSP

A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process in which most molecules are secreted from eukaryotic cells. [GOC:mah, ISBN:0716731363]
GO

Cellular release of secretory products from within membrane-limited vesicles or granules.
NCI

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acetaldehyd

A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
MSH

colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors; also an intermediate in the metabolism of alcohol; has a general narcotic action and also causes irritation of mucous membranes.
CSP

A widespread, naturally occurring, colorless and flammable liquid with a suffocating smell. Acetaldehyde is found in various plants, ripe fruits, vegetables, cigarette smoke, gasoline and diesel exhaust. This substance is widely used in the manufacture of acetic acid, perfumes, dyes and drugs, as a flavoring agent and as an intermediate in the metabolism of alcohol. Acute exposure to its vapors results in irritation of the eyes, skin, and respiratory tract. Acetaldehyde is reasonably anticipated to be a human carcinogen. (NCI05)
NCI

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Cetacea

order of marine mammals; like other mammals they breathe by means of lungs, and bring forth living young which they suckle for some time; the anterior limbs are changed to paddles; the tail flukes are horizontal.
CSP

An order of wholly aquatic MAMMALS occurring in all the OCEANS and adjoining seas of the world, as well as in certain river systems. They feed generally on FISHES, cephalopods, and crustaceans. Most are gregarious and most have a relatively long period of parental care and maturation. Included are DOLPHINS; PORPOISES; and WHALES. (From Walker`s Mammals of the World, 5th ed, pp969-70)
MSH

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protézy – selhání

Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.
MSH

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kernikterus

A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
MSH

brain disorder associated with high levels of bilrubin; clinical features include athetosis, muscle spasticity or hypotonia, impaired vertical gaze, and deafness; nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the blood-brain barrier; this condition occurs primarily in neonates with perinatal blood incompatibilities, but may rarely occur in adults.
CSP

A rare neurologic disorder occurring in infants with jaundice. It results from brain damage by existing high levels of unconjugated-indirect bilirubin.
NCI

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Extravazace

The leakage of body fluid or cells from the vascular system to the surrounding tissues. This process occurs either by force or as a result of a pathologic reaction (e.g., inflammation). This process may sometimes allow cancer cells to migrate from capillaries to adjacent tissues, initiating micro-metastases.
NCI

A discharge or escape, as of blood, from a vessel into the tissues.
NCI

The leakage of blood, lymph, or other fluid, such as an anticancer drug, from a blood vessel or tube into the tissue around it. It is also used to describe the movement of cells out of a blood vessel into tissue during inflammation or metastasis (the spread of cancer).
NCI

The unwanted discharge of a fluid from some container or vessel.
NCI

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Acetylcholinesterase Inhibitors

Any agent that inhibits the enzymatic activity or the synthesis of acetylcholinesterase. Inhibition of acetylcholinesterase prevents breakdown of the neurotransmitter acetylcholine (Ach).
NCI

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farmakologické jevy

The properties and processes of drug metabolism and drug interactions.
MSH

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proteinurie

The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
MSH

presence of excess protein in the urine.
CSP

A disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but also globulin.
NCI

abnormal presence of protein in urine
CHV

The presence of excessive protein, chiefly albumin but also globulin, in the urine.
NCI

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ledviny – papilární nekróza

A complication of kidney diseases characterized by cell death involving KIDNEY PAPILLA in the KIDNEY MEDULLA. Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. Sloughed off necrotic tissue may block KIDNEY PELVIS or URETER. Necrosis of multiple renal papillae can lead to KIDNEY FAILURE.
MSH

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oční víčka – nádory

Tumors of cancer of the EYELIDS.
MSH

new abnormal eyelid tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
CSP

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kyseliny acyklické

Carboxylic acids that have open-chain molecular structures as opposed to ring-shaped structures.
MSH

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kur domácí

Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.
MSH

common name for the species Gallus gallus, the domestic fowl; descended from the red jungle fowl of Southeast Asia.
CSP

The common domestic fowl, Gallus gallus.
NCI

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HAZNAHI PERIANALA

Intense chronic itching in the anal area.
MSH

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kleptomanie

A disorder characterized by the recurrent failure to resist the impulse to steal items of little intrinsic value; the individual experiences a rising subjective sense of tension before the theft and a sense of gratification or relief during the theft.
NCI

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faktor XI

Stable blood coagulation factor involved in the intrinsic pathway. The activated form XIa activates factor IX to IXa. Deficiency of factor XI is often called hemophilia C.
MSH

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akrozóm

The cap-like structure covering the anterior portion of SPERM HEAD. Acrosome, derived from LYSOSOMES, is a membrane-bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in FERTILIZATION.
MSH

cap like structure covering the anterior portion of sperm head; a membrane bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in fertilization.
CSP

A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome. [ISBN:0124325653, ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

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předškolní dítě

A child between the ages of 2 and 5.
MSH

a human child aged 1 through 5 years of age; may include kindergarten age group; also index with appropriate human and clinical research terms.
CSP

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psoraleny

Linear furanocoumarins which are found in many PLANTS, especially UMBELLIFERAE and RUTACEAE, as well as PSORALEA from which they were originally discovered. They can intercalate DNA and, in an UV-initiated reaction of the furan portion, alkylate PYRIMIDINES, resulting in PHOTOSENSITIVITY DISORDERS.
MSH

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L buňky (buněčná linie)

cells from c3h mouse fibroblasts grown in tissue culture that can support replication of many types of viruses.
CSP

A cultured line of C3H mouse FIBROBLASTS that do not adhere to one another and do not express CADHERINS.
MSH

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Fanconiho anémie

Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
MSH

A rare inherited disorder in which the bone marrow does not make blood cells. It is usually diagnosed in children between 2 and 15 years old. Symptoms include frequent infections, easy bleeding, and extreme tiredness. People with Fanconi anemia may have a small skeleton and brown spots on the skin. They also have an increased risk of developing certain types of cancer.
NCI

An autosomal recessive genetic disorder characterized by bone marrow failure, skeletal abnormalities, and an increase incidence of development of neoplasias.
NCI

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Acupuncture Anesthesia

Use of ACUPUNCTURE to block the afferent nerve impulses from reaching the brain to reduce the sensation of pain for surgery.
MSH

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Chlorella

Nonmotile unicellular green algae potentially valuable as a source of high-grade protein and B-complex vitamins.
MSH

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psychologie sociální

The branch of psychology concerned with the effects of group membership upon the behavior, attitudes, and beliefs of an individual.
MSH

study of the behavior and mental processes of individuals in groups, and the interactions of groups.
CSP

The branch of psychology that studies persons and their relationships with others and with groups and with society as a whole.
NCI

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L-laktátdehydrogenasa

do not confuse with EC 1.1.2.3, EC 1.1.2.4, or EC 1.1.2.5, lactate dehydrogenase (cytochrome).
CSP

One of a group of enzymes found in the blood and other body tissues and involved in energy production in cells. An increased amount of lactate dehydrogenase in the blood may be a sign of tissue damage and some types of cancer or other diseases.
NCI

A tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of LACTATE and PYRUVATE. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.
MSH

A family of homotetrameric cytoplasmic enzymes involved in the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.
NCI

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kyseliny mastné omega-3

A group of fatty acids, often of marine origin, which have the first unsaturated bond in the third position from the omega carbon. These fatty acids are believed to reduce serum triglycerides, prevent insulin resistance, improve lipid profile, prolong bleeding times, reduce platelet counts, and decrease platelet adhesiveness.
MSH

group of fatty acids, often of marine origin, which have the first unsaturated bond in the third position from the omega carbon; they are believed to reduce serum triglycerides, prevent insulin resistance, improve lipid profile, prolong bleeding times, reduce platelet counts, and decrease platelet adhesiveness.
CSP

A type of fat obtained in the diet and involved in immunity.
NCI

A class of dietary fatty acids with the first double bond at the 3rd carbon from the methyl end.
NCI

Any fatty acid that contains an unsaturated bond originating from the 3rd carbon from the methyl end. Omega-3 fatty acids do not occur naturally with chain lengths shorter than 16 carbon units.
NCI

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adenom chromofobní

A benign tumor of the anterior pituitary in which the cells do not stain with acidic or basic dyes.
MSH

An epithelial neoplasm of the anterior pituitary gland in which the neoplastic cells do not stain with acidic or basic dyes.
NCI

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chlorfeniramin

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
MSH

histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, asthma and in veterinary applications; one of the most widely used of the classical antihistamines.
CSP

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musculus pterygoideus

Two of the masticatory muscles: the internal, or medial, pterygoid muscle and external, or lateral, pterygoid muscle. Action of the former is closing the jaws and that of the latter is opening the jaws, protruding the mandible, and moving the mandible from side to side.
MSH

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