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Macaca mulatta

species of the genus MACACA inhabiting India, China, and other parts of Asia; the species is used extensively in biomedical research and adapts very well to living with humans.
CSP

A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans.
MSH

A pale brown macaque (Macaca mulatta) native to India, China, and other parts of Asia; often used in medical research. A medium-sized diurnal primate, the Macaca mulatta has a diet of plant material and insects that it can store in pouches in its mouth. The rhesus monkey has an inquisitive, destructive nature with a tendency to bite and pinch; captive breeds are used almost exclusively for medical research. The rhesus monkey has a long history in biomedical research owing to its relative ease in upkeep, most famously utilized in the study of the rhesus factor in human blood groups, the effects of space travel on humans, as well as being the first cloned and transgenic primate.
NCI

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protézy – selhání

Malfunction of implantation shunts, valves, etc., and prosthesis loosening, migration, and breaking.
MSH

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ceftizoxim

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
MSH

A semisynthetic, broad-spectrum, beta-lactamase-resistant, third-generation cephalosporin with antibacterial activity. Ceftizoxime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
NCI

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žaludek – hypotermie

A method of lowering core BODY TEMPERATURE by filling the STOMACH with chilled fluids.
MSH

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Acetylcholinesterase Inhibitors

Any agent that inhibits the enzymatic activity or the synthesis of acetylcholinesterase. Inhibition of acetylcholinesterase prevents breakdown of the neurotransmitter acetylcholine (Ach).
NCI

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magnetismus

The study of MAGNETIC PHENOMENA.
MSH

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proteinurie

The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
MSH

presence of excess protein in the urine.
CSP

A disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. It is predominantly albumin, but also globulin.
NCI

abnormal presence of protein in urine
CHV

The presence of excessive protein, chiefly albumin but also globulin, in the urine.
NCI

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buněčné jadérko

Within most types of eukaryotic CELL NUCLEUS, a distinct region, not delimited by a membrane, in which some species of rRNA (RNA, RIBOSOMAL) are synthesized and assembled into ribonucleoprotein subunits of ribosomes. In the nucleolus rRNA is transcribed from a nucleolar organizer, i.e., a group of tandemly repeated chromosomal genes which encode rRNA and which are transcribed by RNA polymerase I. (Singleton & Sainsbury, Dictionary of Microbiology & Molecular Biology, 2d ed)
MSH

rounded refractile body present in the nucleus of most eukaryotic cells which is the site of synthesis of ribosomal RNA.
CSP

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. [ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

Within most types of eukaryotic CELL NUCLEUS, a distinct region, not delimited by a membrane, in which some species of rRNA (RNA, RIBOSOMAL) are synthesized and assembled into ribonucleoprotein subunits of ribosomes. In the nucleolus rRNA is transcribed from a nucleolar organizer, i.e., a group of tandemly repeated chromosomal genes which encode rRNA and which are transcribed by RNA polymerase I.
NCI

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gefarnát

A water insoluble terpene fatty acid used in the treatment of gastrointestinal ulcers; it facilitates the healing and function of mucosal tissue.
MSH

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kyseliny acyklické

Carboxylic acids that have open-chain molecular structures as opposed to ring-shaped structures.
MSH

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URDAILEKO TUMORE GEIZTOA

A primary or metastatic malignant neoplasm involving the stomach.
NCI

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HAZNAHI PERIANALA

Intense chronic itching in the anal area.
MSH

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nemoci centrálního nervového systému

Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
MSH

condition in which there is a deviation from or interruption of the normal structure or function of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
CSP

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genová přestavba B-lymfocytů

Ordered rearrangement of B-lymphocyte variable gene regions coding for the IMMUNOGLOBULIN CHAINS, thereby contributing to antibody diversity. It occurs during the differentiation of the IMMATURE B-LYMPHOCYTES.
MSH

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akrozóm

The cap-like structure covering the anterior portion of SPERM HEAD. Acrosome, derived from LYSOSOMES, is a membrane-bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in FERTILIZATION.
MSH

cap like structure covering the anterior portion of sperm head; a membrane bound organelle that contains the required hydrolytic and proteolytic enzymes necessary for sperm penetration of the egg in fertilization.
CSP

A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome. [ISBN:0124325653, ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

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nervus mandibularis

A branch of the trigeminal (5th cranial) nerve. The mandibular nerve carries motor fibers to the muscles of mastication and sensory fibers to the teeth and gingivae, the face in the region of the mandible, and parts of the dura.
MSH

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psoraleny

Linear furanocoumarins which are found in many PLANTS, especially UMBELLIFERAE and RUTACEAE, as well as PSORALEA from which they were originally discovered. They can intercalate DNA and, in an UV-initiated reaction of the furan portion, alkylate PYRIMIDINES, resulting in PHOTOSENSITIVITY DISORDERS.
MSH

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mozeček – nemoci

Diseases that affect the structure or function of the cerebellum. Cardinal manifestations of cerebellar dysfunction include dysmetria, GAIT ATAXIA, and MUSCLE HYPOTONIA.
MSH

condition in which there is a deviation from or interruption of the normal structure or function of the cerebellum; manifestations of cerebellar dysfunction include dysmetria, gait ataxia, and muscle hypotonia.
CSP

When you play the piano or hit a tennis ball you are activating the cerebellum. The cerebellum is the area of the brain that controls coordination and balance. Problems with the cerebellum include

  • Cancer
  • Genetic disorders
  • Ataxias – failure of muscle control in the arms and legs that result in movement disorders
  • Degeneration – disorders caused by brain cells decreasing in size or wasting away

Treatment of cerebellar disorders depends on the cause.

NIH: National Institute of Neurological Disorders and Stroke


MEDLINEPLUS

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geny pol

DNA sequences that form the coding region for retroviral enzymes including reverse transcriptase, protease, and endonuclease/integrase. “pol” is short for polymerase, the enzyme class of reverse transcriptase.
MSH

This gene is involved in the replication of the retroviral genome.
NCI

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Acupuncture Anesthesia

Use of ACUPUNCTURE to block the afferent nerve impulses from reaching the brain to reduce the sensation of pain for surgery.
MSH

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nemoc s močí javorového sirupu

An autosomal recessive inherited disorder with multiple forms of phenotypic expression, caused by a defect in the oxidative decarboxylation of branched-chain amino acids (AMINO ACIDS, BRANCHED-CHAIN). These metabolites accumulate in body fluids and render a “maple syrup” odor. The disease is divided into classic, intermediate, intermittent, and thiamine responsive subtypes. The classic form presents in the first week of life with ketoacidosis, hypoglycemia, emesis, neonatal seizures, and hypertonia. The intermediate and intermittent forms present in childhood or later with acute episodes of ataxia and vomiting. (From Adams et al., Principles of Neurology, 6th ed, p936)
MSH

An autosomal recessive inherited disorder caused by mutations in the BCKDHA, BCKDHB, DBT, and DLD genes. It is characterized by a deficiency of branched-chain alpha-keto acid dehydrogenase complex, leading to accumulation of metabolites in the body fluids. The name of the disease derives from the sweet odor of the urine in infants, reminiscent of maple syrup. Signs and symptoms usually appear in infancy and include lethargy and developmental delays. If untreated, it may lead to seizures, coma, and death.
NCI

autosomal recessive inherited disorder with multiple forms of phenotypic expression, caused by a defect in the oxidative decarboxylation of branched-chain amino acids; metabolites accumulate in body fluids and render a “maple syrup” odor; divided into classic, intermediate, intermittent, and thiamine responsive subtypes; classic form presents in the first week of life with ketoacidosis, hypoglycemia, emesis, neonatal seizures, and hypertonia; the intermediate and intermittent forms present in childhood or later with acute episodes of ataxia and vomiting.
CSP

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psychologie sociální

The branch of psychology concerned with the effects of group membership upon the behavior, attitudes, and beliefs of an individual.
MSH

study of the behavior and mental processes of individuals in groups, and the interactions of groups.
CSP

The branch of psychology that studies persons and their relationships with others and with groups and with society as a whole.
NCI

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mozkomíšní mok – proteiny

Proteins in the cerebrospinal fluid, normally albumin and globulin present in the ratio of 8 to 1. Increases in protein levels are of diagnostic value in neurological diseases. (Brain and Bannister`s Clinical Neurology, 7th ed, p221)
MSH

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pohlavní orgány mužské – nádory

Tumor or cancer of the MALE GENITALIA.
MSH

new abnormal tissue of the male reproductive system that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
CSP

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adenom chromofobní

A benign tumor of the anterior pituitary in which the cells do not stain with acidic or basic dyes.
MSH

An epithelial neoplasm of the anterior pituitary gland in which the neoplastic cells do not stain with acidic or basic dyes.
NCI

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plíce – hromadné snímkování

X-ray screening of large groups of persons for diseases of the lung and heart by means of radiography of the chest.
MSH

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musculus pterygoideus

Two of the masticatory muscles: the internal, or medial, pterygoid muscle and external, or lateral, pterygoid muscle. Action of the former is closing the jaws and that of the latter is opening the jaws, protruding the mandible, and moving the mandible from side to side.
MSH

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Cetacea

order of marine mammals; like other mammals they breathe by means of lungs, and bring forth living young which they suckle for some time; the anterior limbs are changed to paddles; the tail flukes are horizontal.
CSP

An order of wholly aquatic MAMMALS occurring in all the OCEANS and adjoining seas of the world, as well as in certain river systems. They feed generally on FISHES, cephalopods, and crustaceans. Most are gregarious and most have a relatively long period of parental care and maturation. Included are DOLPHINS; PORPOISES; and WHALES. (From Walker`s Mammals of the World, 5th ed, pp969-70)
MSH

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germinové octany

Germine derivatives acetylated on any one or more of the hydroxy groups. These compounds are present in many polyester alkaloids which occur in Veratrum and Zygadenus species. They are used as antihypertensive agents, and in some cases, exhibit curare-like activity.
MSH

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adenylylimidodifosfát

5`-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation.
MSH

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