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hydrokodon

Narcotic analgesic related to CODEINE, but more potent and more addicting by weight. It is used also as cough suppressant.
MSH

A semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6.
NCI

a kind of pain relieving drug
CHV

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sourozenci – vztahy

Interactions and relationships between sisters and/or brothers. The concept also applies to animal studies.
MSH

interactions and relationships between sisters and/or brothers.
CSP

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diethyldithiokarbamát

A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
MSH

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nefróza

Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.
MSH

diseases of the kidney characterized by purely degenerative lesions of the renal tubules without an inflammatory component.
CSP

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palmitoylkoenzym A

A fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.
MSH

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bcr-abl fúzové proteiny

Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the genetic locus of the breakpoint cluster region gene on chromosome 22. Several different variants of the bcr-abl fusion proteins occur depending upon the precise location of the chromosomal breakpoint. These variants can be associated with distinct subtypes of leukemias such as PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; and NEUTROPHILIC LEUKEMIA, CHRONIC.
MSH

An onco-protein generated from the fusion of Bcr and Abl genes by translocation process between chromosome 9 and 22 (Philadelphia chromosome), in CML (P210) and some ALL (P190). Aberrant expression of BCR-ABL in bone marrow cells results in a variety of leukemias.
NCI

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hydroxycholekalciferoly

Hydroxy analogs of vitamin D 3; (CHOLECALCIFEROL); including CALCIFEDIOL; CALCITRIOL; and 24,25-DIHYDROXYVITAMIN D 3.
MSH

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siloxany

Silicon polymers that contain alternate silicon and oxygen atoms in linear or cyclic molecular structures.
MSH

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dihydroergokornin

A 9,10alpha-dihydro derivative of ERGOTAMINE that contains isopropyl sidechains at the 2` and 5` positions of the molecule.
MSH

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crista neuralis

The two longitudinal ridges along the PRIMITIVE STREAK appearing near the end of GASTRULATION during development of nervous system (NEURULATION). The ridges are formed by folding of NEURAL PLATE. Between the ridges is a neural groove which deepens as the fold become elevated. When the folds meet at midline, the groove becomes a closed tube, the NEURAL TUBE.
MSH

strip of specialized ectoderm flanking each side of the embryonal neural plate, which after the closure of the neural tube, forms a column of isolated cells along the dorsal aspect of the neural tube; most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells.
CSP

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panika

A state of extreme acute, intense anxiety and unreasoning fear accompanied by disorganization of personality function.
MSH

Sudden extreme anxiety or fear that may cause irrational thoughts or actions. Panic may include rapid heart rate, flushing (a hot, red face), sweating, and trouble breathing.
NCI

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vyznání

a state or habit of mind in which trust or confidence is placed in some person or thing; conviction of the truth of some statement or the reality of some phenomenon.
CSP

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hymenolepiáza

Infection with tapeworms of the genus Hymenolepis.
MSH

A parasitic infection caused by tapeworms. Most infected individuals do not have symptoms. When symptoms appear, they include diarrhea, abdominal pain, restlessness, and irritability.
NCI

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Sjoegrenův-Larssonův syndrom

An autosomal recessive neurocutaneous disorder characterized by severe ichthyosis MENTAL RETARDATION; SPASTIC PARAPLEGIA; and congenital ICHTHYOSIS. It is caused by mutation of gene encoding microsomal fatty ALDEHYDE DEHYDROGENASE leading to defect in fatty alcohol metabolism.
MSH

A rare autosomal recessive inherited metabolic syndrome caused by mutations in the ALDH3A2 gene. It is characterized by deficiency of fatty aldehyde dehydrogenase. It is manifested with congenital ichthyosis, mental retardation, and leg paralysis.
NCI

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dimethoát

An organothiophosphorus cholinesterase inhibitor that is used as a systemic and contact insecticide.
MSH

organothiophosphorus cholinesterase inhibitor that is used as a systemic and contact insecticide.
CSP

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neurologie

A medical specialty concerned with the study of the structures, functions, and diseases of the nervous system.
MSH

the branch of medical science that deals with the study of structure, function, and diseases of the nervous system; for thorough searching also see NEUROSCIENCE, MENTAL DISORDER, NERVOUS SYSTEM DISORDER, NERVOUS SYSTEM DISORDER DIAGNOSIS, MENTAL DISORDER DIAGNOSIS, NERVOUS SYSTEM DISORDER CHEMOTHERAPY, COMMUNICATION DISORDER, NEUROMUSCULAR DISORDER.
CSP

A branch of medicine concerned with the development, anatomy, function, and dysfunction of the nervous system.
NCI

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Paracoccus

Gram-negative non-motile bacteria found in soil or brines.
MSH

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benzidine

A grayish-red, yellowish or white colored, very toxic, crystalline aromatic amine that darkens when exposed to air and light. Benzidine has been widely used for the detection of blood and as a reagent in the manufacture of dyes. Ingestion of benzidine causes cyanosis, headache, mental confusion, nausea and vomiting. Its use is now limited because of strong association between exposure to benzidine and an increased risk of bladder cancer in humans. (NCI05)
NCI

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hyperostóza

Increase in the mass of bone per unit volume.
MSH

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Mephitidae

The family of omnivorous New World skunks, showing typical warning coloration of patterned black and white and able to eject a malodorous secretion when the animal is startled or in danger.
MSH

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Dipetalonema – infekce

Infections with nematodes of the genus DIPETALONEMA.
MSH

A parasitic infection caused by genus of filarial worms called Dipetalonema. It produces microfilariae in the blood and body fluids.
NCI

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neurochirurgie

A surgical specialty concerned with the treatment of diseases and disorders of the brain, spinal cord, and peripheral and sympathetic nervous system.
MSH

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paraparéza tropická spastická

A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239)
MSH

an incurable viral infection of the spinal cord that causes weakness in the legs
CHV

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berberin

An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
MSH

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Hypertropie

Vertical strabismus in which there is permanent upward deviation of the visual axis of one eye.
NCI

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sociální odcizení

The state of estrangement individuals feel in cultural settings that they view as foreign, unpredictable, or unacceptable.
MSH

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katastrofy

Calamities producing great damage, loss of life, and distress. They include results of natural phenomena and man-made phenomena. Normal conditions of existence are disrupted and the level of impact exceeds the capacity of the hazard-affected community.
MSH

unexpected natural or man-made catastrophe of substantial extent causing significant property damage or destruction, loss of life or sometimes permanent changes to the natural environment.
CSP

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nialamid

An MAO inhibitor that is used as an antidepressive agent.
MSH

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paréza

A general term referring to a mild to moderate degree of muscular weakness, occasionally used as a synonym for PARALYSIS (severe or complete loss of motor function). In the older literature, paresis often referred specifically to paretic neurosyphilis (see NEUROSYPHILIS). “General paresis” and “general paralysis” may still carry that connotation. Bilateral lower extremity paresis is referred to as PARAPARESIS.
MSH

A slight or incomplete paralysis.
NCI

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betamethason 17-valerát

The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.
MSH

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