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N-acylneuraminátcytidylyltransferasa

An enzyme that forms CMP-acylneuraminic acids, which donate the N-acylneuraminic acid residues to the terminal sugar residue of a ganglioside or glycoprotein. EC 2.7.7.43.
MSH

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diazoniové sloučeniny

The salt form of diazo compounds, compounds containing the N2 nitrogen attached to only one hydrocarbon, formulated by replacing three hydrogen atoms of the salt of an aryl primary amine by nitrogen having the general structure represented as R-N2X.
NCI

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psychózy toxické

Psychotic organic mental disorders resulting from the toxic effect of drugs and chemicals or other harmful substance.
MSH

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bakteriofágy

Viruses whose hosts are bacterial cells.
MSH

capable of producing transmissible lysis of bacteria; virus particle attaches to bacterial cell wall and viral nucleoprotein enters the cell, resulting in viral synthesis and liberation on bacterial cell lysis.
CSP

A virus that infects and lyses certain bacteria.
NCI

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myofibrily

The long cylindrical contractile organelles of STRIATED MUSCLE cells composed of ACTIN FILAMENTS; MYOSIN filaments; and other proteins organized in arrays of repeating units called SARCOMERES .
MSH

highly organized bundles of actin, myosins, and other proteins in the cytoplasm of skeletal and cardiac muscle cells that contract by a sliding filament mechanism; they are composed of numerous myofilaments.
CSP

The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. [ISBN:0815316194]
GO

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HLA antigeny

Antigens determined by leukocyte loci found on chromosome 6, the major histocompatibility loci in humans. They are polypeptides or glycoproteins found on most nucleated cells and platelets, determine tissue types for transplantation, and are associated with certain diseases.
MSH

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adenosindifosfátové cukry

Esters formed between the aldehydic carbon of sugars and the terminal phosphate of adenosine diphosphate.
MSH

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dicyklohexylkarbodiimid

A carbodiimide that is used as a chemical intermediate and coupling agent in peptide synthesis. (From Hawley`s Condensed Chemical Dictionary, 12th ed)
MSH

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veřejné zdravotnictví – praxe

The activities and endeavors of the public health services in a community on any level.
MSH

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Thoracica

A superorder of marine CRUSTACEA, free swimming in the larval state, but permanently fixed as adults. There are some 800 described species, grouped in several genera, and comprising of two major orders of barnacles: stalked (Pedunculata) and sessile (Sessilia).
MSH

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virus myxomatózy

The type species of LEPORIPOXVIRUS causing infectious myxomatosis, a severe generalized disease, in rabbits. Tumors are not always present.
MSH

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Hodgkinova nemoc

A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin`s and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
MSH

malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue, and the presence of large, usually multinucleate, cells (Reed-Sternberg cells) of unknown origin.
CSP

A lymphoma, previously known as Hodgkin`s disease, characterized by the presence of Reed-Sternberg cells. There are two distinct subtypes: nodular lymphocyte predominant Hodgkin lymphoma and classical Hodgkin lymphoma. Hodgkin lymphoma has a bimodal age distribution, and involves primarily lymph nodes. Current therapy for Hodgkin lymphoma has resulted in an excellent outcome and cure for the majority of patients.
NCI

Hodgkin disease is a type of lymphoma. Lymphoma is cancer of lymph tissue found in the lymph nodes, spleen, liver, and bone marrow. The first sign of Hodgkin disease is often an enlarged lymph node. The disease can spread to nearby lymph nodes. Later it may spread to the lungs, liver or bone marrow. The cause is unknown.

Hodgkin disease is rare. Symptoms include

  • Painless swelling of the lymph nodes in the neck, armpits, or groin
  • Fever and chills
  • Night sweats
  • Weight loss
  • Loss of appetite
  • Itchy skin

Doctors can diagnose Hodgkin disease with a biopsy. This involves removing and examining a piece of tissue under a microscope. Treatment varies depending on how far the disease has spread and often includes radiation therapy or chemotherapy.

The earlier the disease is diagnosed, the more effective the treatment. In most cases, Hodgkin disease can be cured.

NIH: National Cancer Institute


MEDLINEPLUS

A cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell. The two major types of Hodgkin lymphoma are classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats.
NCI

An obsolete term referring to Hodgkin lymphma.
NCI

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řízení

Performing or possessing executive duties; acting as a supervisor or manager.
NCI

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diethyldithiokarbamát

A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
MSH

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Onemocnění pulmonální chlopně

A heart disorder characterized by a defect in pulmonary valve structure or function.
NCI

A disorder characterized by a defect in pulmonary valve function or structure.
NCI

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bcr-abl fúzové proteiny

Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the genetic locus of the breakpoint cluster region gene on chromosome 22. Several different variants of the bcr-abl fusion proteins occur depending upon the precise location of the chromosomal breakpoint. These variants can be associated with distinct subtypes of leukemias such as PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; and NEUTROPHILIC LEUKEMIA, CHRONIC.
MSH

An onco-protein generated from the fusion of Bcr and Abl genes by translocation process between chromosome 9 and 22 (Philadelphia chromosome), in CML (P210) and some ALL (P190). Aberrant expression of BCR-ABL in bone marrow cells results in a variety of leukemias.
NCI

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nehty – nemoci

Diseases of the nail plate and tissues surrounding it. The concept is limited to primates.
MSH

Your toenails and fingernails protect the tissues of your toes and fingers. They are made up of layers of a hardened protein called keratin, which is also in your hair and skin. Your nails` health can be a clue to your overall health. Healthy nails are usually smooth and consistent in color. Specific types of nail discoloration and changes in growth rate can signal various lung, heart, kidney and liver diseases, as well as diabetes and anemia. White spots and vertical ridges are harmless.

Nail problems that sometimes require treatment include bacterial and fungal infections, ingrown nails, tumors and warts. Keeping nails clean, dry and trimmed can help you avoid some problems. Do not remove the cuticle, which can cause infection.


MEDLINEPLUS

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Hormone Receptor

postcoordinate with specific hormone terms if needed.
CSP

A cell protein that binds a specific hormone. The hormone receptor may be on the surface of the cell or inside the cell. Many changes take place in a cell after a hormone binds to its receptor.
NCI

Ligand binding proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell. The hormone receptor can be cytoplasmic/nuclear, or associated with the cell membrane in the case of receptors whose ligands cannot penetrate the membrane.
NCI

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insuficience nadledvin

abnormally diminished activity of the adrenal gland.
CSP

A disorder that occurs when the adrenal cortex does not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex as in Addison`s disease or primary adrenal insufficiency.
NCI

Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.
MSH

An endocrine or hormonal disorder that occurs when the adrenal cortex does not produce enough of the hormone cortisol and in some cases, the hormone aldosterone. It may be due to a disorder of the adrenal cortex (Addison`s disease or primary adrenal insufficiency) or to inadequate secretion of ACTH by the pituitary gland (secondary adrenal insufficiency).
NCI

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dihydroergokornin

A 9,10alpha-dihydro derivative of ERGOTAMINE that contains isopropyl sidechains at the 2` and 5` positions of the molecule.
MSH

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purpura

Purplish or brownish red discoloration, easily visible through the epidermis, caused by hemorrhage into the tissues. When the size of the discolorization is >2-3 cm it is generally called Ecchymoses (ECCHYMOSIS).
MSH

small hemorrhage in the skin, mucous membrane or serosal surface, or a group of hemorrhagic diseases characterized by purpuric lesions.
CSP

A hemorrhagic area of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color.
NCI

A disorder characterized by hemorrhagic areas of the skin and mucous membrane. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color.
NCI

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vyznání

a state or habit of mind in which trust or confidence is placed in some person or thing; conviction of the truth of some statement or the reality of some phenomenon.
CSP

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narkolepsie

A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)
MSH

recurrent, uncontrollable brief episodes of sleep and lapses in consciousness, often associated with hypnagogic hallucinations, cataplexy, automatic behaviors and sleep paralysis.
CSP

A sleep disorder characterized by a tendency for excessive sleepiness during the day which occurs even after adequate sleep in the nighttime. The persons who suffer from this condition experience fatigue and may fall asleep at inappropriate times during the day.
NCI

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nemocnice pro chronická onemocnění

Hospitals which provide care to patients with long-term illnesses.
MSH

(1) A hospital including a physical plant and personnel that provides multidisciplinary diagnosis and treatment for diseases that have one or more of the following characteristics: is permanent; leaves residual disability; is caused by nonreversible pathological alteration; requires special training of the patient for rehabilitation; and/or may be expected to require a long period of supervision or care. In addition, patients require the safety, security, and shelter of these specialized inpatient or partial hospitalization settings. (2) A hospital that provides medical and skilled nursing services to patients with long-term illnesses who are not in an acute phase but who require an intensity of services not available in nursing homes. Source: (1) Expanded from Rhea, Ott, and Shafritz, The Facts On File Dictionary of Health Care Management, New York: Facts On File Publications, 1988.


HL7V3.0

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Aerococcus

A genus of gram-positive cocci in the family AEROCOCCACEAE, occurring as airborne saprophytes.
MSH

A genus of aerobic, Gram positive, cocci shaped bacterium assigned to the phylum Firmicutes and the family Aerococcaceae.
NCI

Any bacteria that is not assigned to the species level but can be assigned to the Aerococcus genus level.
NCI

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dimethoát

An organothiophosphorus cholinesterase inhibitor that is used as a systemic and contact insecticide.
MSH

organothiophosphorus cholinesterase inhibitor that is used as a systemic and contact insecticide.
CSP

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pyreny

A group of condensed ring hydrocarbons.
MSH

polycyclic hydrocarbon, C16H10.
CSP

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benzidine

A grayish-red, yellowish or white colored, very toxic, crystalline aromatic amine that darkens when exposed to air and light. Benzidine has been widely used for the detection of blood and as a reagent in the manufacture of dyes. Ingestion of benzidine causes cyanosis, headache, mental confusion, nausea and vomiting. Its use is now limited because of strong association between exposure to benzidine and an increased risk of bladder cancer in humans. (NCI05)
NCI

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přirozený porod

Labor and delivery without medical intervention, usually involving RELAXATION THERAPY.
MSH

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potřeby pro domácnost

Various material objects and items in the home. It includes temporary or permanent machinery and appliances. It does not include furniture or interior furnishings (FURNITURE see INTERIOR DESIGN AND FURNISHINGS; INTERIOR FURNISHINGS see INTERIOR DESIGN AND FURNISHINGS).
MSH

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