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erytroblasty

Immature, nucleated ERYTHROCYTES occupying the stage of ERYTHROPOIESIS that follows formation of ERYTHROID PRECURSOR CELLS and precedes formation of RETICULOCYTES. The normal series is called normoblasts. Cells called MEGALOBLASTS are a pathologic series of erythroblasts.
MSH

Red blood cells that are at the last stage of development, still containing a nucleus, that are found in the bone marrow and occasionally in the peripheral blood.
NCI

An immature, nucleated erythrocyte occupying the stage of erythropoiesis that follows formation of erythroid progenitor cells and precedes formation of reticulocytes.
NCI

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poddajnost

Distensibility measure of a chamber such as the lungs (LUNG COMPLIANCE) or bladder. Compliance is expressed as a change in volume per unit change in pressure.
MSH

An index reflecting distensibility of elastic organ(s) defined as the change in volume per unit change in pressure (dV/dP).
NCI

testing the extent to which the structure of a organ or a chemical substance can be easily changed
CHV

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skopolamin

An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in URINARY INCONTINENCE, in MOTION SICKNESS, as an antispasmodic, and as a mydriatic and cycloplegic.
MSH

The hydrobromide salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting.
NCI

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jodofory

Complexes of iodine and non-ionic SURFACE-ACTIVE AGENTS acting as carrier and solubilizing agent for the iodine in water. Iodophors usually enhance bactericidal activity of iodine, reduce vapor pressure and odor, minimize staining, and allow wide dilution with water. (From Merck Index, 11th ed)
MSH

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orfenadrin

A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
MSH

A muscarinic antagonist with muscle relaxant activity. Although the mechanism of action has not been determined, orphenadrine appears to block muscarinic acetylcholine receptors as well as N-methyl-D-aspartate (NMDA) receptors in the central nervous system (CNS). This may interfere with the transmission of nerve impulses from the spinal cord to the muscles and may help relax muscles. In addition, orphenadrine exerts antagonistic effects on histamine H1 receptors.
NCI

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divertikly jícnu

Saccular protrusion beyond the wall of the ESOPHAGUS.
MSH

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kondomy

A sheath that is worn over the penis during sexual behavior in order to prevent pregnancy or spread of sexually transmitted disease.
MSH

A condom is a sheath which completely covers the penis with a closely fitting membrane. The condom is used for contraceptive and for prophylactic purposes (preventing transmission of venereal disease). The device may also be used to collect semen to aid in the diagnosis of infertility.
SPN

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Process of secretion

production of a hormone or other substance which will perform a specialized function outside the gland, cell or organ.
CSP

Used for the discharge across the cell membrane, into the extracellular space or ducts, of endogenous substances resulting from the activity of intact cells of glands, tissues, or organs.
MSH

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iridoviry

A family of large icosahedral DNA viruses infecting insects and poikilothermic vertebrates. Genera include IRIDOVIRUS; RANAVIRUS; Chloriridovirus; Megalocytivirus; and Lymphocystivirus.
MSH

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osteitis deformans

A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass. The resultant architecture of the bone assumes a mosaic pattern in which the fibers take on a haphazard pattern instead of the normal parallel symmetry.
MSH

disease marked by repeated episodes of increased bone resorption followed by excessive repair, resulting in weakened, deformed bones of increased mass.
CSP

A disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue. (On-line Medical Dictionary)
NCI

Paget`s disease of bone causes your bones to grow larger and weaker than normal. They also might break easily. The disease can lead to other health problems, too, such as arthritis and hearing loss. You can have Paget`s disease in any bone, but it is most common in the spine, pelvis, skull and legs. The disease might affect one or several bones, but not your entire skeleton. More men than women have the disease. It is most common in older people.

Many people do not know they have Paget`s disease because their symptoms are mild. For others, symptoms can include

  • Pain
  • Enlarged bones
  • Broken bones
  • Damaged cartilage in joints

No one knows what causes Paget`s disease. In some cases, a virus might be responsible. It tends to run in families. You can treat Paget`s disease with medicine and sometimes surgery. A good diet and exercise might also help.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases


MEDLINEPLUS

A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass.
CHV

A chronic condition in which both the breakdown and regrowth of bone are increased. Paget disease of bone occurs most frequently in the pelvic and leg bones, skull, and lower spine. It is most common in older individuals, and may lead to bone pain, deformities, and fractures.
NCI

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estrany

A group of compounds forming the nucleus of the estrogenic steroid family.
MSH

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zachování přírodních zdrojů

The protection, preservation, restoration, and rational use of all resources in the total environment.
MSH

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semeno – uchovávání

The process by which semen is kept viable outside of the organism from which it was derived (i.e., kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism).
MSH

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isoenzymy

Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.
MSH

different form of the same enzyme, such as from another tissue or species, membrane-bound vs. soluble, secreted vs. intracellular, or oligomerized to a different degree.
CSP

The term “isoenzyme” or “isozyme” refers to variants of the same enzyme which can be separated on special conducting media using electrophoresis. It should apply only to those multiple forms of enzymes arising from genetically determined differences in primary structure and not to those derived by modification of the same primary sequence.
NCI

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osteoradionekróza

Necrosis of bone following radiation injury.
MSH

Necrosis of bone following exposure to a source of radiation.
NCI

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etika stomatologická

The principles of proper professional conduct concerning the rights and duties of the dentist, relations with patients and fellow practitioners, as well as actions of the dentist in patient care and interpersonal relations with patient families. (From Stedman, 25th ed)
MSH

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antikoncepční látky orální kombinované

Fixed drug combinations administered orally for contraceptive purposes.
MSH

A pill used to prevent pregnancy. It contains hormones that block the release of eggs from the ovaries. Most birth control pills include estrogen and progestin.
NCI

Orally administered synthetic sex hormones with contraceptive activity. The oral contraceptive preparation contains a combination of an estrogen, such as ethinyl estradiol, and a progestagen, such as levonorgestrel or norethidrone. The oral contraceptive prevents pregnancy by preventing ovulation and by inducing endometrial and cervical changes undesirable for fertilization and implantation.
NCI

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L-serindehydratasa

A PYRIDOXAL-phosphate containing enzyme that catalyzes the dehydration and deamination of L-serine to form pyruvate. This enzyme was formerly listed as EC 4.2.1.13.
MSH

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isoxsuprin

A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
MSH

A benzyl alcohol derivative with vasodilator activity. The mechanism of action of isoxsuprine hydrochloride is controversial, because isoxsuprine has beta-adrenergic activities that could not be offset by beta-adrenergic blockers. Although stimulation of the beta adrenergic receptor increases blood flow to produce vasodilatation, this agent may also have direct effects on the contractility of smooth muscle. Additionally, isoxsuprine causes relaxation of uterine smooth muscle and may also produce positive inotropic and chronotropic effects on the myocardium.
NCI

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přeučení

Learning in which practice proceeds beyond the point where the act can just be performed with the required degree of excellence.
MSH

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ethylenchlorhydrin

Used as a solvent, in the manufacture of insecticides, and for treating sweet potatoes before planting. May cause nausea, vomiting, pains in head and chest, stupefaction. Irritates mucous membranes and causes kidney and liver degeneration.
MSH

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koproporfyrinogeny

Porphyrinogens which are intermediates in the heme biosynthesis. They have four methyl and four propionic acid side chains attached to the pyrrole rings. Coproporphyrinogens I and III are formed in the presence of uroporphyrinogen decarboxylase from the corresponding uroporphyrinogen. They can yield coproporphyrins by autooxidation or protoporphyrin by oxidative decarboxylation.
MSH

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setariáza

Infection with nematodes of the genus Setaria. This condition is usually seen in cattle and equines and is of little pathogenic significance, although migration of the worm to the eye may lead to blindness.
MSH

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zaměstnání – žádost o místo

Process of applying for employment. It includes written application for employment or personal appearance.
MSH

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oximy

Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.
MSH

compounds containing the group C=NOH.
CSP

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eugenol

A cinnamate derivative of the shikamate pathway found in CLOVE OIL and other PLANTS.
MSH

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ohledači mrtvol a lékařští vyšetřovatelé

Physicians appointed to investigate all cases of sudden or violent death.
MSH

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sexuálně přenosné nemoci bakteriální

Bacterial diseases transmitted or propagated by sexual conduct.
MSH

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srpkovitá anémie

A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
MSH

disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs; the clinical expression of homozygosity for hemoglobin S.
CSP

Sickle cell anemia is a disease in which your body produces abnormally shaped red blood cells. The cells are shaped like a crescent or sickle. They don`t last as long as normal, round red blood cells, which leads to anemia. The sickle cells also get stuck in blood vessels, blocking blood flow. This can cause pain and organ damage.

A genetic problem causes sickle cell anemia. People with the disease are born with two sickle cell genes, one from each parent. If you only have one sickle cell gene, it`s called sickle cell trait. About 1 in 12 African Americans has sickle cell trait. A blood test can show if you have the trait or anemia. Most states test newborn babies as part of their newborn screening programs.


MEDLINEPLUS

An inherited disease in which the red blood cells have an abnormal crescent shape, block small blood vessels, and do not last as long as normal red blood cells. Sickle cell anemia is caused by a mutation (change) in one of the genes for hemoglobin (the substance inside red blood cells that binds to oxygen and carries it from the lungs to the tissues). It is most common in people of West and Central African descent.
NCI

A blood disorder characterized by the appearance of sickle-shaped red blood cells and anemia.
NCI

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guma karaya

Polysaccharide gum from Sterculia urens (STERCULIA). It is used as a suspending or stabilizing agent in foods, cosmetics and pharmaceuticals; a bulk-forming laxative; a surgical lubricant and adhesive; and in the treatment of skin ulcers.
MSH

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