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cholecystitida

inflammation of the gallbladder; generally caused by impairment of bile flow, gallstones in the biliary tract, infections, or other diseases.
CSP

A disorder characterized by inflammation involving the gallbladder. It may be associated with the presence of gallstones.
NCI

An acute or chronic inflammation involving the gallbladder wall. It may be associated with the presence of gallstones.
NCI

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alkohol – otrava

An acute brain syndrome which results from the excessive ingestion of ETHANOL or ALCOHOLIC BEVERAGES.
MSH

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magie

Beliefs and practices concerned with producing desired results through supernatural forces or agents as with the manipulation of fetishes or rituals.
MSH

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záření – poranění

Harmful effects of non-experimental exposure to ionizing or non-ionizing radiation in VERTEBRATES.
MSH

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gastrointestinální nádory

Tumors or cancer of the GASTROINTESTINAL TRACT, from the MOUTH to the ANAL CANAL.
MSH

new abnormal gastrointestinal tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease; use for general gastrointestinal tract neoplasms.
CSP

A benign or malignant neoplasm involving any part of the gastrointestinal system.
NCI

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cholesterol-7-alfa-hydroxylasa

A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.
MSH

Encoded by human CYP7A1 Gene (Cytochrome P450 Family), 504-aa 58-kDa Cytochrome P450 7A1 is an endoplasmic reticulum membrane-bound P450 heme-thiolate monooxygenase in the liver that catalyzes the first (rate-limiting) reaction in the cholesterol catabolic pathway: cholesterol conversion to bile acids, the major site of regulation of bile acid synthesis and the primary mechanism for removal of cholesterol from the body. P450 enzymes catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. (NCI)
NCI

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alkálie

Usually a hydroxide of lithium, sodium, potassium, rubidium or cesium, but also the carbonates of these metals, ammonia, and the amines. (Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

A chemical that can dissolve in water, combine with acids to form salts, and make acids less acidic. Alkalis have a bitter taste and turn certain dyes blue. Some alkalis can help the body work the way it should. An example of an alkali is sodium hydroxide.
NCI

Refers to the amount of alkali. An alkali is a chemical that can dissolve in water, combine with acids to form salts, and make acids less acidic.
NCI

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Malajsie

southeast Asian country, capital Kuala Lumpur.
CSP

A parliamentary democracy with a constitutional monarch in southeast Asia, consisting of 11 states (West Malaysia) on the Malay Peninsula and two states (East Malaysia) on the island of BORNEO. It is also called the Federation of Malaysia. Its capital is Kuala Lumpur. Before 1963 it was the Union of Malaya. It reorganized in 1948 as the Federation of Malaya, becoming independent from British Malaya in 1957 and becoming Malaysia in 1963 as a federation of Malaya, Sabah, Sarawak, and Singapore (which seceded in 1965). The form Malay- probably derives from the Tamil malay, mountain, with reference to its geography. (From Webster`s New Geographical Dictionary, 1988, p715 & Room, Brewer`s Dictionary of Names, 1992, p329)
MSH

A country in Southeastern Asia, occupying a peninsula and the northern one-third of the island of Borneo, bordering Indonesia and the South China Sea, south of Vietnam. (NCI)
NCI

A country in Southeastern Asia, occupying a peninsula and the northern one-third of the island of Borneo, bordering Indonesia and the South China Sea, south of Vietnam. (CIA World Factbook 2002)
NCI

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rentgendiagnostika panoramatická

Extraoral body-section radiography depicting an entire maxilla, or both maxilla and mandible, on a single film.
MSH

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geny – frekvence

The proportion of one particular in the total of all ALLELES for one genetic locus in a breeding POPULATION.
MSH

the relative occurrence of a specific allele at a given locus in a population, usually expressed in percent.
CSP

A description of the relative rate of occurrence of specific alleles, traits, or other factors within a population of organisms.
NCI

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choriokarcinom

A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
MSH

malignant metastatic form of trophoblastic tumors, contains sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts; characterized by the large amounts of chorionic gonadotropin produced; tissue origins can be placental (fetal) or non-placental.
CSP

A malignant, fast-growing tumor that develops from trophoblastic cells (cells that help an embryo attach to the uterus and help form the placenta). Almost all choriocarcinomas form in the uterus after fertilization of an egg by a sperm, but a small number form in a testis or an ovary. Choriocarcinomas spread through the blood to other organs, especially the lungs. They are a type of gestational trophoblastic disease.
NCI

An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected.
NCI

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alylamin

Possesses an unusual and selective cytotoxicity for VASCULAR SMOOTH MUSCLE cells in dogs and rats. Useful for experiments dealing with arterial injury, myocardial fibrosis or cardiac decompensation.
MSH

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řízení – bilance

Management review designed to evaluate efficiency and to identify areas in need of management improvement within the institution in order to ensure effectiveness in meeting organizational goals.
MSH

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déšť

Water particles that fall from the ATMOSPHERE.
MSH

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geny gag

DNA sequences that form the coding region for proteins associated with the viral core in retroviruses. gag is short for group-specific antigen.
MSH

This gene is involved in retroviral core structure.
NCI

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chromatografie gelová

Chromatography on non-ionic gels without regard to the mechanism of solute discrimination.
MSH

column chromatography that separates compounds on the basis of molecular size by using a molecular sieve, usually a zeolite; molecules larger than the largest pore size are excluded from the column.
CSP

Gel permeation or sieve chromatography that is performed on porous gels that separate solutes on the basis of size. Smaller solutes are included within the particles of the gel matrix more frequently than larger solutes, thus affecting elution rates.
NCI

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alfaprodin

An opioid analgesic chemically related to and with an action resembling that of MEPERIDINE, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1067)
MSH

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alfa-mannosidóza

An autosomal recessive lysosomal storage disease characterized by deficient activity of the enzyme alpha-D-mannosidase. There is a wide range of signs and symptoms including hepatomegaly, splenomegaly, hearing loss, respiratory infections, mental retardation, skeletal abnormalities, leveled nasal bridge and protruding forehead.
NCI

An inborn error of metabolism marked by a defect in the lysosomal isoform of ALPHA-MANNOSIDASE activity that results in lysosomal accumulation of mannose-rich intermediate metabolites. Virtually all patients have psychomotor retardation, facial coarsening, and some degree of dysostosis multiplex. It is thought to be an autosomal recessive disorder.
MSH

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potkani Sprague-Dawley

A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
MSH

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Genetics, Biochemical

The science concerned with the chemical and physical nature of genes and the genome.
NCI

A branch of genetics which deals with the chemical structure of the genes and with the mechanisms by which the genes control and regulate the structure and synthesis of proteins.
MSH

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chromozómy lidské, 21-22 a Y

The short, acrocentric human chromosomes, called group G in the human chromosome classification. This group consists of chromosome pairs 21 and 22 and the Y chromosome.
MSH

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amblyopie

A nonspecific term referring to impaired vision. Major subcategories include stimulus deprivation-induced amblyopia and toxic amblyopia. Stimulus deprivation-induced amblyopia is a developmental disorder of the visual cortex. A discrepancy between visual information received by the visual cortex from each eye results in abnormal cortical development. STRABISMUS and REFRACTIVE ERRORS may cause this condition. Toxic amblyopia is a disorder of the OPTIC NERVE which is associated with ALCOHOLISM, tobacco SMOKING, and other toxins and as an adverse effect of the use of some medications.
MSH

impairment of vision without detectable organic lesion of the eye.
CSP

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manželství

The social institution involving legal and/or religious sanction whereby men and women are joined together for the purpose of founding a family unit.
MSH

The social institution involving legal and/or religious sanction whereby men and women are joined together for the purpose of founding a family unit; the state of being a married couple.
NCI

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receptory komplementu

molecules on the surface of some B-lymphocytes and macrophages, that recognize and combine with the C3b, C3d, C1q, and C4b components of complement.
CSP

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geriatrický odhad

Evaluation of the level of physical, physiological, or mental functioning in the older population group.
MSH

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Chrysosporium

A mitosporic Onygenaceae fungal genus which causes adiaspiromycosis, a pulmonary mycosis of man and rodents. One of its teleomorphs is Ajellomyces.
MSH

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amidinotransferasy

Enzymes of a subclass of TRANSFERASES that catalyze the transfer of an amidino group from donor to acceptor. EC 2.1.4.
MSH

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mastocytóza

A heterogenous group of disorders characterized by the abnormal increase of MAST CELLS in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).
MSH

rare disease characterized by an abnormal increase in mast cells in the bone marrow, liver, spleen, lymph nodes, gastrointestinal tract, and skin.
CSP

A clonal myeloproliferative neoplasm characterized by the proliferation and accumulation of neoplastic mast cells in one or multiple organs or organ systems. It is a heterogeneous group of neoplasms, ranging from cutaneous proliferations which may regress spontaneously, to aggressive neoplasms associated with organ failure and short survival.
NCI

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receptory nikotinové

One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.
MSH

classic ligand-gated ion channel receptor type, where binding of ligand (acetylcholine) to transmembrane protein oligomer causes channel to open, permitting ion (sodium and potassium) flux and depolarization.
CSP

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gigantismus

The condition of accelerated and excessive GROWTH in children or adolescents who are exposed to excess HUMAN GROWTH HORMONE before the closure of EPIPHYSES. It is usually caused by somatotroph hyperplasia or a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. These patients are of abnormally tall stature, more than 3 standard deviations above normal mean height for age.
MSH

condition of abnormal overgrowth or excessive size of the whole body or any of its parts.
CSP

A clinical finding indicating abnormal and excessive body growth and height resulting from the overproduction of human growth hormone.
NCI

A condition in which the whole body or any of its parts grow much larger than normal.
NCI

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