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kyselina penicilová

A mycotoxin with antibiotic and carcinogenic activity produced by various strains of PENICILLIUM and ASPERGILLUS. It has been found in tobacco, sausages, and corn.
MSH

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fibrózní dysplazie polyostotická

FIBROUS DYSPLASIA OF BONE affecting several or many bones. When associated with melanotic pigmentation of the skin and endocrine disorders, it is known as Albright`s syndrome. (From Dorland, 28th ed)
MSH

A genetic syndrome caused by mutations in the GNAS1 gene. It is characterized by deformities and fractures of the bones, endocrine abnormalities including early puberty, and skin hyperpigmentation.
NCI

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specifická hmotnost

The ratio of the density of a material to the density of some standard material, such as water or air, at a specified temperature.
MSH

The density (mass per unit volume) of any material divided by that of water at a standard temperature.
NCI

A ratio of the density of a fluid to the density of water.
NCI

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Lepidoptera

have 4 membranous wings covered with scales, sucking mouth parts, and lack mandibles; undergo complete metamorphosis; larvae may be serious pests of cultivated plants, stored foods, or fabrics.
CSP

A large order of insects comprising the butterflies and moths.
MSH

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mozkomíšní mok – zkraty

Tubes inserted to create communication between a cerebral ventricle and the internal jugular vein. Their emplacement permits draining of cerebrospinal fluid for relief of hydrocephalus or other condition leading to fluid accumulation in the ventricles.
MSH

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Sodium Stibogluconate

Pentavalent antimony (Sb) in differential complex formation with gluconic acid with established leishmanicidal use and potential antitumor activity. The Sb moiety of sodium stibogluconate (SSG) may inhibit protein tyrosine phophorylases (PTPases) by covalently modifying sulfhydryl groups in PTPase cysteine residues, resulting in specific inactivation of SH2 domain-containing tyrosine phosphatases-1 and -2 (SHP-1 and SHP-2), PTPases which negatively regulate interferon (IFN) signaling; enhancement of IFN-induced Stat1 tyrosine phosphorylation; and induction of cellular protein tyrosine phosphorylation. SSG in combination with IFN-alpha may synergize to overcome tumor cell resistance to IFN-alpha-mediated apoptosis. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=475763&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=475763&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61083″ NCI Thesaurus)
PDQ

Pentavalent antimony (Sb) in differential complex formation with gluconic acid with leishmanicidal and potential antineoplastic activities. The Sb moiety of sodium stibogluconate (SSG) may inhibit protein tyrosine phosphorylases (PTPases) by covalently modifying sulfhydryl groups in PTPase cysteine residues, resulting in specific inactivation of SH2 domain-containing tyrosine phosphatases-1 and -2 (SHP-1 and SHP-2), PTPases which negatively regulate interferon (IFN) signaling; enhancement of IFN-induced Stat1 tyrosine phosphorylation; and induction of cellular protein tyrosine phosphorylation. SSG in combination with IFN-alpha may synergize to overcome tumor cell resistance to IFN-alpha-mediated apoptosis.
NCI

A substance being studied in the treatment of certain solid tumors, lymphoma, and myeloma. Sodium stibogluconate may block enzymes needed for cancer growth. It is a type of pentavalent antimonial.
NCI

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žhářství

A compulsion to set fires.
MSH

A disorder characterized by a fascination with fire and recurrent episodes of fire setting during which the individual experiences a rising subjective sense of tension before the fire setting and a sense of gratification or relief when setting the fire. There is no ulterior motive (such as monetary gain or the expression of political ideology) to the fire setting.
NCI

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spermie – počet

A count of SPERM in the ejaculum, expressed as number per milliliter.
MSH

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leukémie erytroblastická akutní

A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.
MSH

myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.
CSP

Cancer of the blood-forming tissues in which large numbers of immature, abnormal red blood cells are found in the blood and bone marrow.
NCI

Acute erythroid leukemia characterised by the presence of at least 50% erythroid precursors and at least 20% myeloblasts in the bone marrow. — 2003
NCI

An acute myeloid leukemia characterized by a predominant immature erythroid population. There are two subtypes recognized: erythroleukemia and pure erythroid leukemia. Severe anemia is a common symptom. This leukemia usually follows an aggressive clinical course. (WHO, 2001)
NCI

Acute erythroid leukemia characterised by the presence of immature erythroid cells in the bone marrow (at least 80% of the cellular component), without evidence of a significant myeloblastic cell population present. — 2003
NCI

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cetomakrogol

Non-ionic surfactant of the polyethylene glycol family. It is used as a solubilizer and emulsifying agent in foods, cosmetics, and pharmaceuticals, often as an ointment base, and also as a research tool.
MSH

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Peptostreptococcus

A genus of gram-positive, anaerobic, coccoid bacteria that is part of the normal flora of humans. Its organisms are opportunistic pathogens causing bacteremias and soft tissue infections.
MSH

A genus of anaerobic, Gram positive, cocci shaped bacterium assigned to the phylum Firmicutes and the family Peptostreptococcaceae.
NCI

Any bacteria that is not assigned to the species level but can be assigned to the Peptostreptococcus genus level.
NCI

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flekainid

A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial arrhythmias and tachycardias. Paradoxically, however, in myocardial infarct patients with either symptomatic or asymptomatic arrhythmia, flecainide exacerbates the arrhythmia and is not recommended for use in these patients.
MSH

A synthetic agent derived from trifluoroethoxy-benzamide exhibiting antiarrhythmic and local anesthetic activity. As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system. It also decreases phase 4 slope and increases the depolarization threshold. (NCI04)
NCI

A drug that is used to treat abnormal heart rhythms. It may also relieve neuropathic pain, the burning, stabbing, or stinging pain that may arise from damage to nerves caused by some types of cancer or cancer treatment.
NCI

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sfingolipidy

A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)
MSH

family of ceramides with various hydrophilic, O-linked head groups; found in membranes, especially in neural tissue.
CSP

A class of dietary lipids containing a long-chained sphingosine group (unsaturated amino alcohol with formula C18H37NO2), fatty acids bound to the NH2 group as an amide, and either sugars or phosphoric acid and alcohols bound to the primary hydroxy group .
NCI

Any lipid derived from the aliphatic amino alcohol sphingosine, in which a single fatty acid is covalently bound to sphingosine via an amide linkage. Various ester-linked substituents can result in generation of ceramides, sphingomyelins and glycosphingolipids.
NCI

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leukocyty – faktory inhibice migrace

Protein factor(s) released by sensitized lymphocytes (and possibly other cells) that inhibit the movement of LEUKOCYTES, especially polymorphonuclear cells, away from their site of release. Assays for these factors are used as tests for cellular immunity. Two of the common assays are the LEUKOCYTE MIGRATION CAPILLARY TUBE TECHNIQUE (LMCT) and the LEUKOCYTE MIGRATION AGAROSE TEST (LMAT).
MSH

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chemically induced

Used for biological phenomena, diseases, syndromes, congenital abnormalities, or symptoms caused by endogenous or exogenous substances.
MSH

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perikard

A conical fibro-serous sac surrounding the HEART and the roots of the great vessels (AORTA; VENAE CAVAE; PULMONARY ARTERY). Pericardium consists of two sacs, the outer fibrous pericardium and the inner serous pericardium. The latter consists of an outer parietal layer facing the fibrous pericardium, and an inner visceral layer (epicardium) resting next to the heart, and a pericardial cavity between these two layers.
MSH

Serous sac that surrounds the heart. Examples: There is only one pericardial sac.
UWDA

membranous sac that envelops the heart and the roots of the great vessels.
CSP

Serous sac, which has as parts the serous pericardium and the pericardial cavity . Examples: There is only one pericardial sac.
FMA

Organ cluster which has as its parts the fibrous pericardium and the pericardial sac.
FMA

A conical membranous sac filled with serous fluid in which the heart as well as the roots of the aorta and other large blood vessels are contained. (NCI)
NCI

membrane sac surrounding the heart muscle
CHV

A conical membranous sac filled with serous fluid in which the heart as well as the roots of the aorta and other large blood vessels are contained.
NCI

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fluorescenční angiografie

Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.
MSH

visualization of a vascular system after intravenous injection of a fluorescein solution; images may be photographed or televised; used especially in studying the retinal and uveal vasculature.
CSP

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Spirillum

A genus of gram-negative, curved and spiral-shaped bacteria found in stagnant, freshwater environments. These organisms are motile by bipolar tufts of flagella having a long wavelength and about one helical turn. Some species of Spirillum cause a form of RAT-BITE FEVER.
MSH

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Libérie

A republic in western Africa, south of GUINEA and east of COTE D`IVOIRE. Its capital is Monrovia.
MSH

A country in Western Africa, bordering the North Atlantic Ocean, between Cote d`Ivoire and Sierra Leone. (NCI)
NCI

A country in Western Africa, bordering the North Atlantic Ocean, between Cote d`Ivoire and Sierra Leone. (CIA World Factbook 2002)
NCI

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virus chikungunya

A species of ALPHAVIRUS causing an acute dengue-like fever.
MSH

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periplazmatické vazebné proteiny

Periplasmic proteins that scavenge or sense diverse nutrients. In the bacterial environment they usually couple to transporters or chemotaxis receptors on the inner bacterial membrane.
MSH

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zrudnutí

A transient reddening of the face that may be due to fever, certain drugs, exertion, stress, or a disease process.
MSH

A disorder characterized by episodic reddening of the face.
NCI

Flush


HL7V3.0

A sudden reddening of the face.
NCI

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spory bakterií a nižších rostlin

The reproductive elements of lower organisms, such as BACTERIA; FUNGI; and cryptogamic plants.
MSH

a small, usually unicellular, reproductive body from which a new organism arises; produced by some plants (ferns and mosses), fungi, bacteria, and protozoa.
CSP

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systémy udržující život

Systems that provide all or most of the items necessary for maintaining life and health. Provisions are made for the supplying of oxygen, food, water, temperature and pressure control, disposition of carbon dioxide and body waste. The milieu may be a spacecraft, a submarine, or the surface of the moon. In medical care, usually under hospital conditions, LIFE SUPPORT CARE is available. (From Webster`s New Collegiate Dictionary)
MSH

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nechtěné dítě

The child who is not wanted by one or both parents.
MSH

child not wanted by one or both parents.
CSP

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personální útvar nemocnice

Management activities concerned with hospital employees.
MSH

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potraviny – označování

Use of written, printed, or graphic materials upon or accompanying a food or its container or wrapper. The concept includes ingredients, nutritional value, directions, warnings, and other relevant information.
MSH

With all the different products grocery stores offer, it can be hard to make the best food choices. Food labels can make the task a little easier. The U.S. Food and Drug Administration requires packaged foods to carry labels.

On every food label you will see

Food and Drug Administration


MEDLINEPLUS

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Staphylocoagulase

An extracellular protein which specifically forms a complex with human prothrombin. This complex named staphylothrombin can clot fibrinogen without any proteolytic cleavage of prothrombin.
MSH

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ret

Either of the two fleshy, full-blooded margins of the mouth.
MSH

upper or lower flesh margin of the mouth.
CSP

Fleshy fold which surrounds the opening of the mouth. (NCI)
NCI

Fleshy fold which surrounds the opening of the mouth.
NCI

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chlorfenvinfos

An organophosphorus cholinesterase inhibitor that is used as an insecticide and an acaricide.
MSH

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