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virus chikungunya

A species of ALPHAVIRUS causing an acute dengue-like fever.
MSH

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infekce

Invasion of the host organism by microorganisms that can cause pathological conditions or diseases.
MSH

invasion and growth of microorganisms in body tissues, which may be clinically inapparent or result in local cellular injury; a local infection may persist and spread by extension to become an acute, subacute, or chronic clinical infection or disease state or it may become systemic when the microorganisms gain access to the lymphatic or vascular system; does not always lead to injury of the host even if the pathogen is potentially virulent.
CSP

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Retroviridae – infekce

virus diseases caused by the Retroviridae family.
CSP

Virus diseases caused by the RETROVIRIDAE.
MSH

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nechtěné dítě

The child who is not wanted by one or both parents.
MSH

child not wanted by one or both parents.
CSP

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parenterální infúze

The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping.
MSH

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rinofyma

A manifestation of severe ROSACEA resulting in significant enlargement of the NOSE and occurring primarily in men. It is caused by hypertrophy of the SEBACEOUS GLANDS and surrounding CONNECTIVE TISSUE. The nose is reddened and marked with TELANGIECTASIS.
MSH

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chlorfenvinfos

An organophosphorus cholinesterase inhibitor that is used as an insecticide and an acaricide.
MSH

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inositol

An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
MSH

cyclic sugar alcohol, the fully hydroxylated derivative of cyclohexane, occurring naturally in a variety of stereoisomers, most commonly, the myo-isomer, myoinositol, a member of the vitamin B complex and a component of phosphatidylinositols.
CSP

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Myoinositol helps cells make membranes and respond to messages from their environment. It has the same chemical formula as glucose (the chief source of energy for living organisms) but has a different arrangement of atoms. It is found in beans, peas, brown rice, wheat bran and nuts. It is water-soluble (can dissolve in water) and must be taken in every day. Myoinositol is being studied in the prevention of cancer.
NCI

A natural sugar found in cell membrane phospholipids, plasma lipoproteins, and (as the phosphate form) in the nucleus with potential chemopreventive properties. As one of a number of intracellular phosphate compounds, inositol is involved in cell signaling and may stimulate tumor cell differentiation. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=305828&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=305828&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28163″ NCI Thesaurus)
PDQ

A natural sugar found in cell membrane phospholipids, plasma lipoproteins, and (as the phosphate form) in the nucleus with potential chemopreventive properties. As one of a number of intracellular phosphate compounds, inositol is involved in cell signaling and may stimulate tumor cell differentiation. (NCI04)
NCI

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riboflavinsynthasa

An enzyme that catalyzes the formation of riboflavin from two molecules of 6,7-dimethyl-8-ribityllumazine, utilizing a four-carbon fragment from one molecule which is transferred to the second molecule. EC 2.5.1.9.
MSH

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chlorfentermin

A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of DEXTROAMPHETAMINE. It has been implicated in lipid storage disorders and pulmonary hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1223)
MSH

A chlorinated analogue of phentermine, a sympathomimetic amine with central nervous system (CNS) stimulating and anorexic activity. Chlorphentermine acts by facilitating the release of catecholamines, especially noradrenaline and dopamine, from nerve terminals in the brain and also inhibits their uptake. The increase in synaptic concentrations of these catecholamines causes behavioral changes including an increase in motor activity, mental alertness and excitement, causes euphoria, and suppresses appetite.
NCI

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instrumentation aspects

Used with diagnostic or therapeutic procedures, analytic techniques, and specialties or disciplines, for the development or modification of apparatus, instruments, or equipment.
MSH

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rickettsiové vakcíny

Vaccines for the prevention of diseases caused by various species of Rickettsia.
MSH

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Cholera Toxin Protomer A

The catalytic subunit of cholera toxin. It is proteolytically cleaved into fragments A1 and A2. The A1 fragment is a MONO(ADP-RIBOSE) TRANSFERASE.
MSH

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jaderná matrix

The residual framework structure of the CELL NUCLEUS that maintains many of the overall architectural features of the cell nucleus including the nuclear lamina with NUCLEAR PORE complex structures, residual CELL NUCLEOLI and an extensive fibrogranular structure in the nuclear interior. (Advan. Enzyme Regul. 2002; 42:39-52)
MSH

network of proteinaceous structural elements in the nucleus, comparable to the cytoskeleton of the cytoplasm, responsible for large- scale translocations such as chromosome movement, spliceosome and mRNA transport, etc.
CSP

The dense fibrillar network lying on the inner side of the nuclear membrane. [ISBN:0582227089]
GO

A fibrogranular network of residual structural elements within which are immersed both chromatin and ribonucleoproteins. It appears to extend throughout the nuclear interior from the nucleolus to the nuclear pore complexes along the nuclear periphery.
NCI

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pojištění ošetřovatelských služeb

Insurance providing benefits for the costs of care provided by nurses, especially nurse practitioners and nurse clinicians.
MSH

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RNA sondy

RNA, usually prepared by transcription from cloned DNA, which complements a specific mRNA or DNA and is generally used for studies of virus genes, distribution of specific RNA in tissues and cells, integration of viral DNA into genomes, transcription, etc. Whereas DNA PROBES are preferred for use at a more macroscopic level for detection of the presence of DNA/RNA from specific species or subspecies, RNA probes are preferred for genetic studies. Conventional labels for the RNA probe include radioisotope labels 32P and 125I and the chemical label biotin. RNA probes may be further divided by category into plus-sense RNA probes, minus-sense RNA probes, and antisense RNA probes.
MSH

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epidemiologické metody

Epidemiological methods involve sophisticated statistics and higher mathematics. These methods allow epidemiologists to address issues like non-experimental studies of mechanistic questions in disease etiology, including studies of the impact of the social position of individuals in different social contexts.
NCI

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cholinesterasy

enzyme of the hydrolase class that catalyzes the cleavage of the acyl group from various esters of choline, including acetylcholine, and some related compounds the enzyme occurs primarily in the serum, liver, and pancreas determination of enzyme activity is used to test liver function, succinylcholine sensitivity, and whether organophosphate insecticide poisoning has occurred.
CSP

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nukleotidyltransferasy

A class of enzymes that transfers nucleotidyl residues. EC 2.7.7.
MSH

nucleotidyltransferases. Enzymes (EC class 2.7.7) transferring nucleotide residues (nucleotidyls) from nucleoside di- or triphosphates into dimer or polymer forms. Some nucleotidyltransferases bear specific names (e.g., adenylyltransferases), or trivial names indicating the linkage hydrolyzed in the synthesis (pyrophosphorylases, phosphorylases), or names of the material synthesized (RNA or DNA polymerase).
NCI

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interleukin-5

A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells.
MSH

lymphokine produced by antigen or mitogen activated T lymphocytes that acts as a differentiation factor for B lymphocytes and eosinophils and increases the production of IgA by B lymphocytes.
CSP

One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-5 is made mainly by some T lymphocytes. It causes B lymphocytes to make more antibodies and increases the number of eosinophils. IL-5 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. It is a type of cytokine.
NCI

Human interleukin-5 protein (134 aa, 15 kDa precursor) is encoded by the human interleukin-5 (IL5) gene. This cytokine acts as a growth and differentiation factor for eosinophils and induces terminal differentiation of B-cells which become Ig-secreting cells. It is thought to play a pivotal role in the pathogenesis of asthma. Elevated levels of this protein have been detected in both asthma and hypereosinophilic syndromes.
NCI

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RNA transferová Ile

A transfer RNA which is specific for carrying isoleucine to sites on the ribosomes in preparation for protein synthesis.
MSH

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SUDUR ODOLJARIOA/EPISTASIA

Bleeding from the nose.
MSH

A disorder characterized by bleeding from the nose.
NCI

Bleeding from the nose.
NCI

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choroidea – nádory

Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).
MSH

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ošetřovatelské služby

A general concept referring to the organization and administration of nursing activities.
MSH

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tazatelé

The person who manages an interview and asks the questions.
NCI

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kořenové kanálky – irigační prostředky

Chemicals used mainly to disinfect root canals after pulpectomy and before obturation. The major ones are camphorated monochlorophenol, EDTA, formocresol, hydrogen peroxide, metacresylacetate, and sodium hypochlorite. Root canal irrigants include also rinsing solutions of distilled water, sodium chloride, etc.
MSH

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ergoliny

A series of structurally-related alkaloids that contain the ergoline backbone structure.
MSH

series of structurally-related alkaloids that contain the ergoline backbone structure.
CSP

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Chromobacterium

A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria occurring in soil and water. Its organisms are generally nonpathogenic, but some species do cause infections of mammals, including humans.
MSH

A genus of aerobic, Gram negative, coccobacilli shaped bacterium in the phylum Proteobacteria and the family Neisseriaceae.
NCI

Any bacteria that is not assigned to the species level but can be assigned to the Chromobacterium genus level.
NCI

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odchylka pozorovatele

The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer`s missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material).
MSH

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intrinsic faktor

A glycoprotein secreted by the cells of the GASTRIC GLANDS that is required for the absorption of VITAMIN B 12 (cyanocobalamin). Deficiency of intrinsic factor leads to VITAMIN B 12 DEFICIENCY and ANEMIA, PERNICIOUS.
MSH

glycoprotein secreted by the cells of the gastric glands that is required for the absorption of Vitamin B12.
CSP

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