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Macaca nemestrina

found in Southeast Asia, Sumatra and Borneo; medium length tail carried arched over back, crown hairs form horse-shoe shaped patch, females conspicuous purple-pink sexual swelling at estrus.
CSP

A species of the genus MACACA which inhabits Malaya, Sumatra, and Borneo. It is one of the most arboreal species of Macaca. The tail is short and untwisted.
MSH

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receptory estrogenů

cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription; evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.
CSP

Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important.
MSH

A protein found inside the cells of the female reproductive tissue, some other types of tissue, and some cancer cells. The hormone estrogen will bind to the receptors inside the cells and may cause the cells to grow.
NCI

Widely expressed human Estrogen Receptors (NR3 Family) are cytoplasmic hormone-activated receptors that act as nuclear transcription factors composed of an N-terminal transcription activation/modulation domain, a DNA-binding domain, and a C-terminal steroid-binding domain. Binding to DNA as a homo- or heterodimer, ESR interacts with NCOA3, NCOA5, and NCOA6 coactivators. Hormone-ESR complexes appear to recognize discrete upstream target ERE DNA sequences to regulate gene expression, cell proliferation, and differentiation. DNA-binding is lost in the absence of ligand. (NCI)
NCI

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žaludeční inhibiční polypeptid

A gastrointestinal peptide hormone of about 43-amino acids. It is found to be a potent stimulator of INSULIN secretion and a relatively poor inhibitor of GASTRIC ACID secretion.
MSH

secreted by the mucosa of the upper small intestine; has a mild effect in decreasing motor activity of the stomach and therefore slowing the emptying of gastric contents into the duodenum.
CSP

a kind of gastrointestinal hormone
CHV

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karcinom bronchogenní

Malignant neoplasm arising from the epithelium of the BRONCHI. It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA.
MSH

group of carcinomas of the lung, arising from the epithelium of the bronchial tree.
CSP

Cancer that begins in the tissue that lines or covers the airways of the lungs, including small cell and non-small cell lung cancer.
NCI

A lung carcinoma arising from the bronchial epithelium.
NCI

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aminokyseliny – isomerasy

Enzymes that catalyze either the racemization or epimerization of chiral centers within amino acids or derivatives. EC 5.1.1.
MSH

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magnetoencefalografie

The measurement of magnetic fields over the head generated by electric currents in the brain. As in any electrical conductor, electric fields in the brain are accompanied by orthogonal magnetic fields. The measurement of these fields provides information about the localization of brain activity which is complementary to that provided by ELECTROENCEPHALOGRAPHY. Magnetoencephalography may be used alone or together with electroencephalography, for measurement of spontaneous or evoked activity, and for research or clinical purposes.
MSH

measurement of magnetic activity of the brain, usually conducted externally by sensitive devices such as SQUID`s; electric currents generated in the brain by neural activity are accompanied by orthogonal magnetic fields and the measurement of these fields provide information about the localization of brain activity which is complementary to that provided by electroencephalography.
CSP

The measurement of the magnetic fields produced by electrical activity in the brain, usually conducted externally, using extremely sensitive devices. The measurement of electric fields in the brain provides information about the localization of brain activity which is complementary to that provided by electroencephalography.
NCI

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receptory thyreoidních hormonů

Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively.
MSH

A nuclear receptor that specifically binds to and is activated by thyroid hormone.
NCI

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Geiger-teller

A radiation counter that uses a radiation-counter tube, operated in the Geiger range, to detect and count ionizing particles. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
MSH

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kardiotokografie

Monitoring of fetal heart frequency before birth in order to assess impending prematurity in relation to the pattern or intensity of antepartum UTERINE CONTRACTION.
MSH

The monitoring of both maternal uterine contractions and fetal heart rate during the process of labor and delivery.
NCI

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aminopeptidasy

A subclass of EXOPEPTIDASES that act on the free N terminus end of a polypeptide liberating a single amino acid residue. EC 3.4.11.
MSH

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simulování

Simulation of symptoms of illness or injury with intent to deceive in order to obtain a goal, e.g., a claim of physical illness to avoid jury duty.
MSH

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referenční standardy

A basis of value established for the measure of quantity, weight, extent or quality, e.g. weight standards, standard solutions, methods, techniques, and procedures used in diagnosis and therapy.
MSH

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genová přestavba – těžký řetězec B-lymfocytů

Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.
MSH

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ossa carpi

The eight bones of the wrist: SCAPHOID BONE; LUNATE BONE; TRIQUETRUM BONE; PISIFORM BONE; TRAPEZIUM BONE; TRAPEZOID BONE; CAPITATE BONE; and HAMATE BONE.
MSH

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AMP-deaminasa

An enzyme that catalyzes the deamination of AMP to IMP. EC 3.5.4.6.
MSH

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mandibula – protézy

A prosthetic appliance for the replacement of areas of the mandible missing or defective as a result of deformity, disease, injury, or surgery.
MSH

A mandibular implant facial prosthesis is a device that is intended to be implanted for use in the functional reconstruction of mandibular deficits. The device is made of materials such as stainless steel, tantalum, titanium, cobalt-chromium based alloy, polytetrafluoroethylene, silicone elastomer, polyethylene, polyurethane, or polytetrafluoroethylene with carbon fibers composite.
SPN

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rehabilitace

Restoration of human functions to the maximum degree possible in a person or persons suffering from disease or injury.
MSH

research directed towards restoration or improvement of functional capability lost as a consequence of injury, disease, congenital disorder, or natural aging process; for through searching, see RTs.
CSP

After a serious injury, illness or surgery, you may recover slowly. You may need to regain your strength, relearn skills or find new ways of doing things you did before. This process is rehabilitation.

Rehabilitation often focuses on

  • Physical therapy to help your strength, mobility and fitness
  • Occupational therapy to help you with your daily activities
  • Speech-language therapy to help with speaking, understanding, reading, writing and swallowing
  • Treatment of pain

The type of therapy and goals of therapy may be different for different people. For example, an older person who has had a stroke may simply want rehabilitation to be able to dress or bathe without help. A younger person who has had a heart attack may go through cardiac rehabilitation to try to return to work and normal activities.


MEDLINEPLUS

In medicine, a process to restore mental and/or physical abilities lost to injury or disease, in order to function in a normal or near-normal way.
NCI

Restoration of the ability to function in a normal or near normal manner following disease, illness, or injury.
NCI

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geny recesivní

Genes that influence the PHENOTYPE only in the homozygous state.
MSH

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katastrofická nemoc

An acute or prolonged illness usually considered to be life-threatening or with the threat of serious residual disability. Treatment may be radical and is frequently costly.
MSH

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amyotrofická laterální skleróza

A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
MSH

progressive degeneration of the neurons that give rise to the corticospinal tract and of the motor cells of the brain stem and spinal cord, resulting in a deficit of upper and lower motor neurons.
CSP

Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons transmit messages from your brain and spinal cord to your voluntary muscles – the ones you can control, like in your arms and legs. At first, this causes mild muscle problems. Some people notice

  • Trouble walking or running
  • Trouble writing
  • Speech problems

Eventually, you lose your strength and cannot move. When muscles in your chest fail, you cannot breathe. A ventilator can help, but most people with ALS die from respiratory failure.

The disease usually strikes between age 40 and 60. More men than women get it. No one knows what causes ALS. It can run in families, but usually it strikes at random. There is no cure. Medicines can relieve symptoms and, sometimes, prolong survival.

NIH: National Institute of Neurological Disorders and Stroke


MEDLINEPLUS

An autosomal dominant inherited form of amyloidosis.
NCI

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analgetika

Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
MSH

compounds capable of relieving pain without the loss of consciousness or without producing anesthesia.
CSP

Drugs that reduce pain. These drugs include aspirin, acetaminophen, and ibuprofen.
NCI

Natural or synthetic compound mixtures, Analgesic Preparations relieve pain by altering the perception of nociceptive stimuli without loss of consciousness. Analgesic compounds may act at opioid receptors (morphine-like drugs) or at other central or peripheral sites (non-steroidal anti-inflammatory agents). (NCI04)
NCI

A medication used to relieve pain.
NCI

Compounds that alleviate pain without loss of consciousness. Analgesics act by various mechanisms including binding with opioid receptors and decreasing inflammation. Choice of analgesic may be determined by the type of pain. These compounds include opioid, non-opioid and adjuvant analgesic agents.
NCI

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marihuana – abúzus

The excessive use of marijuana with associated psychological symptoms and impairment in social or occupational functioning.
MSH

excessive use of marijuana with associated psychological symptoms and impairment in social or occupational functioning.
CSP

Marijuana is a dry, shredded mix of flowers, stems, seeds and leaves of the hemp plant Cannabis sativa. People usually smoke it as a cigarette or in a pipe. It is the most commonly abused illegal drug in the United States.

Abusing marijuana can result in problems with memory, learning and social behavior. It can interfere with family, school, work and other activities.

Scientific studies are underway to test the safety and usefulness of cannabis compounds for treating certain medical conditions. Currently, smoking marijuana is not recommended for the treatment of any disease or condition.

NIH: National Institute on Drug Abuse


MEDLINEPLUS

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chymosin

The predominant milk-clotting enzyme from the true stomach or abomasum of the suckling calf. It is secreted as an inactive precursor called prorennin and converted in the acid environment of the stomach to the active enzyme. EC 3.4.23.4.
MSH

do not confuse with RENIN, EC 3.4.23.15.
CSP

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zeměpisné pojmy

header term for any geographic location; for D43 grants, and R03 TW grants (Fogarty International Center awards), index specific country when possible.
CSP

All of the continents and every country situated within, the UNITED STATES and each of the constituent states arranged by region, CANADA and each of its provinces, AUSTRALIA and each of its states, the major bodies of water and major islands on both hemispheres, and selected major cities. Although the geographic locations are not printed in INDEX MEDICUS as main headings, in indexing they are significant in epidemiologic studies and historical articles and for locating administrative units in education and the delivery of health care.
MSH

Any demarcated area of the Earth; may be determined by both natural and human boundaries.
NCI

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Cebus

A genus of the family CEBIDAE, subfamily CEBINAE, consisting of four species which are divided into two groups, the tufted and untufted. C. apella has tufts of hair over the eyes and sides of the head. The remaining species are without tufts – C. capucinus, C. nigrivultatus, and C. albifrons. Cebus inhabits the forests of Central and South America.
MSH

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androgeny

Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
MSH

compounds that interact with androgen receptors in target tissues to bring about the effects similar to those of testosterone; depending on the target tissues, androgenic effects can be on sexual differentiation, male reproductive organs, spermtogenesis, secondary male sex characteristics, libido, development of muscle mass, strength, and power.
CSP

A type of hormone that promotes the development and maintenance of male sex characteristics.
NCI

a kind of male sex hormone
CHV

A class of sex hormones associated with the development and maintenance of the secondary male sex characteristics, sperm induction, and sexual differentiation. In addition to increasing virility and libido, they also increase nitrogen and water retention and stimulate skeletal growth. (MeSH)
NCI

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mastektomie segmentální

Removal of only enough breast tissue to ensure that the margins of the resected surgical specimen are free of tumor.
MSH

Surgery to remove abnormal tissue or cancer from the breast and a small amount of normal tissue around it. It is a type of breast-sparing surgery.
NCI

The removal of a cancer as well as some of the breast tissue around the tumor and the lining over the chest muscles below the tumor. Usually some of the lymph nodes under the arm are also taken out.
NCI

The removal of a cancer as well as some of the breast tissue around the tumor and the lining over the chest muscles below the tumor. Usually some of the lymph nodes under the arm are also taken out. Also called partial mastectomy. (Cancer.gov)
NCI

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stěhování obyvatelstva a migrace

Frequent change of residence, either in the same city or town, or between cities, states or communities.
MSH

change of residence, either in the same city or town, or between cities, states or communities.
CSP

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obrovské buňky s cizími tělesy

Multinucleated cells (fused macrophages), characteristic of granulomatous inflammation, which form around exogenous material in the skin. They are similar in appearance to Langhans giant cells (GIANT CELLS, LANGHANS), but foreign-body giant cells have more abundant chromatin and their nuclei are scattered in an irregular pattern in the cytoplasm.
MSH

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buňky – kompartmentace

A partitioning within cells due to the selectively permeable membranes which enclose each of the separate parts, e.g., mitochondria, lysosomes, etc.
MSH

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