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betaxolol

A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
MSH

A racemic mixture and selective beta-1 adrenergic receptor antagonist with antihypertensive and anti-glaucoma activities and devoid of intrinsic sympathomimetic activity. Betaxolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. When applied topically in the eye, this agent reduces aqueous humor secretion and lowers the intraocular pressure (IOP). In addition, betaxolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels.
NCI

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výdaje na zdravotnictví

The amounts spent by individuals, groups, nations, or private or public organizations for total health care and/or its various components. These amounts may or may not be equivalent to the actual costs (HEALTH CARE COSTS) and may or may not be shared among the patient, insurers, and/or employers.
MSH

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perkuse

Act of striking a part with short, sharp blows as an aid in diagnosing the condition beneath the sound obtained.
MSH

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District of Columbia

A federal area located between Maryland and Virginia on the Potomac river; it is coextensive with Washington, D.C., which is the capital of the United States.
MSH

The area in the United States comprised of a 68 square mile area northeast of the Potomac River donated by the state of Maryland. The District of Columbia, also known as D.C., is not a state, nor is it part of any state. It is a “federal district” established by the US Constitution as the seat of government. The district is occupied entirely by the city of Washington. (from SEERS 2004 codeset)
NCI

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ketony

functional group of an organic compound in which a carbon atom is double-bonded to an oxygen; neither of the other substituents attached to the carbon can be a hydrogen.
CSP

A type of chemical substance used in perfumes, paints, solvents, and found in essential oils (scented liquid taken from plants). Ketones are also made by the body when there is not enough insulin.
NCI

Organic compounds with a carbonyl group (C=O) bonded to two other carbon atoms as the skeleton structure. Acetone is the simplest ketone compound.
NCI

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mícha – nemoci

Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.
MSH

pathologic conditions which feature spinal cord damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord.
CSP

Your spinal cord is the part of your nervous system that relays messages to and from your brain. It is housed inside your vertebrae, which are the bone disks that make up your spine. Normally, your vertebrae protect your spinal cord. If they don`t, you can sustain a spinal cord injury. Besides injuries, the spinal cord can develop

Symptoms vary but might include pain, numbness, loss of sensation and muscle weakness. These symptoms can occur around the spinal cord, and also in other areas such as your arms and legs. Treatments vary but often include medicines and surgery.


MEDLINEPLUS

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dyskineze žlučových cest

A motility disorder characterized by biliary COLIC, absence of GALLSTONES, and an abnormal GALLBLADDER ejection fraction. It is caused by gallbladder dyskinesia and/or SPHINCTER OF ODDI DYSFUNCTION.
MSH

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oční nemoci

Diseases affecting the eye.
MSH

impairment of health or a condition of abnormal functioning of the organ of sight.
CSP

Any deviation from the normal structure or function of the eye that is manifested by a characteristic set of symptoms and signs. (NCI)
NCI

Some eye problems are minor and fleeting. But some lead to a permanent loss of vision. Common eye problems include

  • Cataracts – clouded lenses
  • Glaucoma – damage to the optic nerve from too much pressure in the eye
  • Retinal disorders – problems with the nerve layer at the back of the eye
  • Conjunctivitis – an infection also known as pinkeye

Your best defense is to have regular checkups, because eye diseases do not always have symptoms. Early detection and treatment could prevent vision loss. See an eye care professional right away if you have a sudden change in vision or everything looks dim or if you see flashes of light. Other symptoms that need quick attention are pain, double vision, fluid coming from the eye and inflammation.

NIH: National Eye Institute


MEDLINEPLUS

Any deviation from the normal structure or function of the eye that is manifested by a characteristic set of symptoms and signs.
NCI

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periodika

Publications intended to be issued on an ongoing basis, generally more frequently than annually, containing separate articles, stories, or writings.
MSH

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transpozibilní elementy DNA

Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.
MSH

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křemelina

A form of SILICON DIOXIDE composed of skeletons of prehistoric aquatic plants which is used for its ABSORPTION quality, taking up 1.5-4 times its weight in water. The microscopic sharp edges are useful for insect control but can also be an inhalation hazard. It has been used in baked goods and animal feed. Kieselguhr is German for flint + earthy sediment.
MSH

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spirostany

Cholestane derivatives containing a fused lactone ring at the 16,17-position and a spiroglycosidic linkage at C-22. Members include sarsaponin, DIOSGENIN and yamogenin.
MSH

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biologická dostupnost

The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
MSH

The rate and extent to which the active ingredient or active moiety is absorbed from a drug product and becomes available at the site of action. For drug products that are not intended to be absorbed into the bloodstream, bioavailability may be assessed by measurements intended to reflect the rate and extent to which the active ingredient or active moiety becomes available at the site of action (21CFR320.1).
NCI

the amount of drug that reaches the blood after it has been administered
CHV

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AURPEGIKO MINA

Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.
MSH

Painful sensation in the face.
NCI

A disorder characterized by a sensation of marked discomfort in the face.
NCI

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peritonitida

INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.
MSH

inflammation of the peritoneum, a condition marked by exudations in the peritoneum of serum, fibrin, cells, and pus.
CSP

inflammation of the thin membrane surrounding abdominal cavity, called peritoneum
CHV

Inflammation of the peritoneum (tissue that lines the abdominal wall and covers most of the organs in the abdomen). Peritonitis can result from infection, injury, or certain diseases. Symptoms may include swelling of the abdomen, severe pain, and weight loss.
NCI

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proteiny vážící DNA

Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
MSH

diverse group of viral and genetic regulatory proteins which bind in a sequence-specific manner to DNA, and share common structural motifs such as the “zinc-finger,” “helix-turn-helix,” and “leucine zipper.”
CSP

Proteins that non-covalently interact with deoxyribonucleic acid as a result of intermolecular physical forces and spatial complementarity. Many genetic regulatory DNA binding proteins bind to double- or single-stranded DNA in a sequence-specific manner and share common structural motifs such as the zinc-finger, helix-turn-helix, and leucine zipper.
NCI

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Korea

Former kingdom, located on Korea Peninsula between Sea of Japan and Yellow Sea on east coast of Asia. In 1948, the kingdom ceased and two independent countries were formed, divided by the 38th parallel.
MSH

Description:Realm code for use of Korea


HL7V3.0

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sprue tropická

A chronic malabsorption syndrome, occurring mainly in residents of or visitors to the tropics or subtropics. The failed INTESTINAL ABSORPTION of nutrients from the SMALL INTESTINE results in MALNUTRITION and ANEMIA that is due to FOLIC ACID deficiency.
MSH

chronic malabsorption syndrome occuring mainly in residents of or visitors to the tropics or subtropics; failed intestinal absorption of nutrients results in malnutrition and anemia due to folate deficiency.
CSP

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bioformation

Used for the anabolic formation of chemical substances in organisms, in living cells, or by subcellular fractions.
MSH

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fakulta ošetřovatelská

The teaching staff and members of the administrative staff having academic rank in a nursing school.
MSH

Nurse educators are registered nurses prepared at the graduate or doctoral level who prepare students for nursing practice at a variety of levels, including entry level, continuing education, advanced practice, and specialty practice. Nurse educators work in various settings, including colleges/universities, community colleges, hospitals, nursing homes, private practice, etc.
NCI

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perylen

A 20-carbon dibenz(de,kl)anthracene that can be viewed as a naphthalene fused to a phenalene or as dinaphthalene. It is used as fluorescent lipid probe in the cytochemistry of membranes and is a polycyclic hydrocarbon pollutant in soil and water. Derivatives may be carcinogenic.
MSH

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dvojitá slepá metoda

A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
MSH

A clinical trial in which the medical staff, the patient, and the people who analyze the results do not know the specific type of treatment the patient receives until after the clinical trial is over.
NCI

A study in which neither the subject nor the investigator nor the research team interacting with the subject or data during the trial knows what treatment a subject is receiving. (CDISC glossary)
NCI

A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment. (MSH2001)
NCI

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porodní děj – předčasný nástup

onset of labor before term but after the fetus has become viable, in humans usually sometime between the 20th and 37th week of gestation.
CSP

Ouster of a viable infant before the normal end of gestation, commonly defined as interruption of pregnancy between the twentieth-thirty seventh completed weeks after the onset of the last menstrual cycle.
NCI

A disorder characterized by delivery of a viable infant before the normal end of gestation. Typically, viability is achievable between the twentieth and thirty-seventh week of gestation.
NCI

Onset of OBSTETRIC LABOR before term (TERM BIRTH) but usually after the FETUS has become viable. In humans, it occurs sometime during the 29th through 38th week of PREGNANCY. TOCOLYSIS inhibits premature labor and can prevent the BIRTH of premature infants (INFANT, PREMATURE).
MSH

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synthasa škrobu

An enzyme that catalyzes the transfer of glucose from ADPglucose to glucose-containing polysaccharides in 1,4-alpha-linkages. EC 2.4.1.21.
MSH

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hemoglobinurická horečka

A complication of MALARIA, FALCIPARUM characterized by the passage of dark red to black urine.
MSH

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Fasciolidae

A family of flukes of the class Trematoda occurring primarily in the liver of animals and man. There are six genera: Fasciola, Fasciolopsis, Fascioloides, Tenuifasciola, Parafasciolopsis, and Protofasciola. The adult form of Fasciolopsis occurs in the intestines of pigs and man.
MSH

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farmakokinetika

Dynamic and kinetic mechanisms of exogenous chemical and drug ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and TOXICOLOGY as a function of dosage, and rate of METABOLISM. It includes toxicokinetics, the pharmacokinetic mechanism of the toxic effects of a substance. ADME and ADMET are short-hand abbreviations for absorption, distribution, metabolism, elimination and toxicology.
MSH

distribution and effectiveness of a drug throughout the body as a function of route, schedule, vehicle, chemical isomer, metabolism, and other factors.
CSP

The activity of drugs in the body over a period of time, including the processes by which drugs are absorbed, distributed in the body, localized in the tissues, and excreted.
NCI

how a drug is absorbed, distributed, metabolized, and eliminated by the body
CHV

The characteristic movements of drugs within biological systems, as affected by absorption, distribution, binding, elimination, biotransformation, and excretion; particularly the rates of such movements.
NCI

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léky – antagonismus

Phenomena and pharmaceutics of compounds that inhibit the function of agonists (DRUG AGONISM) and inverse agonists (DRUG INVERSE AGONISM) for a specific receptor. On their own, antagonists produce no effect by themselves to a receptor, and are said to have neither intrinsic activity nor efficacy.
MSH

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laktoperoxidasa

An enzyme derived from cow`s milk. It catalyzes the radioiodination of tyrosine and its derivatives and of peptides containing tyrosine.
MSH

nonEC.
CSP

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sterilizace

The destroying of all forms of life, especially microorganisms, by heat, chemical, or other means.
MSH

The process that effectively kills or eliminates transmissible agents.
NCI

The destroying of all forms of life, especially microorganisms, by heat, chemical, or other means
CHV

Any substance or process that is used primarily on non-living objects to kill germs, such as viruses, bacteria, and other microorganisms that can cause infection and disease. Most disinfectants are harsh chemicals but sometimes heat or radiation may be used.
NCI

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