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kyselina salicylová

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics. (From Dorland`s, 28th ed)
MSH

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District of Columbia

A federal area located between Maryland and Virginia on the Potomac river; it is coextensive with Washington, D.C., which is the capital of the United States.
MSH

The area in the United States comprised of a 68 square mile area northeast of the Potomac River donated by the state of Maryland. The District of Columbia, also known as D.C., is not a state, nor is it part of any state. It is a “federal district” established by the US Constitution as the seat of government. The district is occupied entirely by the city of Washington. (from SEERS 2004 codeset)
NCI

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hallux valgus

Lateral displacement of the great toe (HALLUX), producing deformity of the first METATARSOPHALANGEAL JOINT with callous, bursa, or bunion formation over the bony prominence.
MSH

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oligodendroglie

A class of large neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal (not the same as SATELLITE CELLS, PERINEURONAL of GANGLIA) according to their location. They form the insulating MYELIN SHEATH of axons in the central nervous system.
MSH

neuroglial cells of ectodermal origin whose processes form the myelin sheath around neuronal axons of the CNS.
CSP

A cell that forms the myelin sheath (a layer that covers and protects nerve cells) in the brain and spinal cord. An oligodendrocyte is a type of glial cell.
NCI

A class of neuroglial (macroglial) cells in the central nervous system. Oligodendroglia may be called interfascicular, perivascular, or perineuronal satellite cells according to their location. The most important recognized function of these cells is the formation of the insulating myelin sheaths of axons in the central nervous system. (MeSH)
NCI

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dyskineze žlučových cest

A motility disorder characterized by biliary COLIC, absence of GALLSTONES, and an abnormal GALLBLADDER ejection fraction. It is caused by gallbladder dyskinesia and/or SPHINCTER OF ODDI DYSFUNCTION.
MSH

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metoklopramid

A dopamine D2 antagonist that is used as an antiemetic.
MSH

A drug that increases the motility (movements and contractions) of the stomach and upper intestine. It is used to treat certain stomach problems and nausea and vomiting caused by chemotherapy. It is a type of antiemetic and a type of motility agent.
NCI

A substituted benzamide and a derivative of para-aminobenzoic acid (PABA) that is structurally related to procainamide, with gastroprokinetic and antiemetic effects. Metoclopramide exerts its prokinetic effect by antagonizing dopamine mediated relaxation effect on gastrointestinal smooth muscle. This enhances the response of the gastrointestinal smooth muscle to cholinergic stimulation, thereby leading to an increase of gastric emptying into the intestines. Metoclopramide may also strengthen the lower esophagus sphincter, thereby preventing acid reflux. This agent antagonizes D2 dopamine receptors in chemoreceptive trigger zone (CTZ) of the medulla, thereby preventing nausea and vomiting.
NCI

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salsolinové alkaloidy

Tetrahydroisoquinolinol alkaloids in both dextro and levo forms, originally found in SALSOLA plants.
MSH

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transpozibilní elementy DNA

Discrete segments of DNA which can excise and reintegrate to another site in the genome. Most are inactive, i.e., have not been found to exist outside the integrated state. DNA transposable elements include bacterial IS (insertion sequence) elements, Tn elements, the maize controlling elements Ac and Ds, Drosophila P, gypsy, and pogo elements, the human Tigger elements and the Tc and mariner elements which are found throughout the animal kingdom.
MSH

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haringtoniny

Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. They are esters of the alkaloid cephalotaxine and may be effective as antineoplastic agents.
MSH

tetracyclic spiro-benzazepine isolated from the seeds of Cephalotaxus; esters of the alkaloid cephalotaxine may be effective as antineoplastic agents.
CSP

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Oncorhynchus

A genus of the family SALMONIDAE (salmons and trouts). They are named for their hooked (onco) nose (rhynchus). They are usually anadromous and occasionally inhabit freshwater. They can be found in North Pacific coastal areas from Japan to California and adjacent parts of the Arctic Ocean. Salmon and trout are popular game and food fish. Various species figure heavily in genetic, metabolism, and hormone research.
MSH

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biologická dostupnost

The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
MSH

The rate and extent to which the active ingredient or active moiety is absorbed from a drug product and becomes available at the site of action. For drug products that are not intended to be absorbed into the bloodstream, bioavailability may be assessed by measurements intended to reflect the rate and extent to which the active ingredient or active moiety becomes available at the site of action (21CFR320.1).
NCI

the amount of drug that reaches the blood after it has been administered
CHV

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mikrobiální testy citlivosti

Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
MSH

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viry satelitní

Defective viruses which can multiply only by association with a helper virus which complements the defective gene. Satellite viruses may be associated with certain plant viruses, animal viruses, or bacteriophages. They differ from satellite RNA; (RNA, SATELLITE) in that satellite viruses encode their own coat protein.
MSH

RNA molecules that depend on co-infection of a host cell with a helper virus for multiplication; most are associated with plant viruses.
CSP

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proteiny vážící DNA

Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases.
MSH

diverse group of viral and genetic regulatory proteins which bind in a sequence-specific manner to DNA, and share common structural motifs such as the “zinc-finger,” “helix-turn-helix,” and “leucine zipper.”
CSP

Proteins that non-covalently interact with deoxyribonucleic acid as a result of intermolecular physical forces and spatial complementarity. Many genetic regulatory DNA binding proteins bind to double- or single-stranded DNA in a sequence-specific manner and share common structural motifs such as the zinc-finger, helix-turn-helix, and leucine zipper.
NCI

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nemocenské pojištění pro staré a invalidy, oddíl 18

Federal program, created by Public Law 89-97, Title XVIII-Health Insurance for the Aged, a 1965 amendment to the Social Security Act, that provides health insurance benefits to persons over the age of 65 and others eligible for Social Security benefits. It consists of two separate but coordinated programs: hospital insurance (MEDICARE PART A) and supplementary medical insurance (MEDICARE PART B). (Hospital Administration Terminology, AHA, 2d ed and A Discursive Dictionary of Health Care, US House of Representatives, 1976)
MSH

Medicare is the U.S. government`s health insurance program for people age 65 or older. Certain people under age 65 can qualify for Medicare, too, including those with disabilities, permanent kidney failure or amyotrophic lateral sclerosis.

Medicare helps with the cost of health care, but it does not cover all medical expenses or the cost of most long-term care. The program has four parts:

  • Part A is hospital insurance.
  • Part B helps pay for medical services that Part A doesn`t cover.
  • Part C is called Medicare Advantage. If you have Parts A and B, you can choose this option to receive all of your health care through a provider organization, like an HMO.
  • Part D is prescription drug coverage. It helps pay for some medicines.


MEDLINEPLUS

A U.S. federal health insurance program for people aged 65 years or older and people with certain disabilities. Medicare pays for hospital stays, medical services, and some prescription drugs but people who receive Medicare must pay part of their healthcare costs.
NCI

The US federal health insurance program run by the Health Care Financing Administration for people 65 years of age or older, certain people with disabilities who have not reached this age, and individuals with permanent kidney failure with dialysis or a transplant. People over 65 years old, younger disabled people, and dialysis patients are eligible for the program regardless of their income. Participating beneficiaries pay part of healthcare costs through deductible amounts. Limited monthly premiums are required from beneficiaries for non-hospital coverage.
NCI

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opium

The air-dried exudate from the unripe seed capsule of the opium poppy, Papaver somniferum, or its variant, P. album. It contains a number of alkaloids, but only a few – MORPHINE; CODEINE; and PAPAVERINE – have clinical significance. Opium has been used as an analgesic, antitussive, antidiarrheal, and antispasmodic.
MSH

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bioformation

Used for the anabolic formation of chemical substances in organisms, in living cells, or by subcellular fractions.
MSH

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Microscope slide

Tissue processing equipment consists of devices used to prepare human tissue specimens for diagnostic histological examination by processing specimens through the various stages of decalcifying, infiltrating, sectioning, and mounting on microscope slides.
SPN

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dezorganizovaná schizofrenie

A type of schizophrenia characterized by frequent incoherence; marked loosening of associations, or grossly disorganized behavior and flat or grossly inappropriate affect that does not meet the criteria for the catatonic type; associated features include extreme social withdrawal, grimacing, mannerisms, mirror gazing, inappropriate giggling, and other odd behavior. (Dorland, 27th ed)
MSH

A subtype of schizophrenia characterized by disorganized speech, disorganized behavior, and a flat or inappropriate affect; associated features include grimacing, mannerisms, and other oddities of behavior. Criteria for the catatonic type of schizophrenia are not met.
NCI

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dvojitá slepá metoda

A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.
MSH

A clinical trial in which the medical staff, the patient, and the people who analyze the results do not know the specific type of treatment the patient receives until after the clinical trial is over.
NCI

A study in which neither the subject nor the investigator nor the research team interacting with the subject or data during the trial knows what treatment a subject is receiving. (CDISC glossary)
NCI

A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment. (MSH2001)
NCI

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sluch

The ability or act of sensing and transducing ACOUSTIC STIMULATION to the CENTRAL NERVOUS SYSTEM. It is also called audition.
MSH

sensation of sound.
CSP

The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. [GOC:ai]
GO

process whereby auditory stimuli are selected, organized and interpreted by the organism.
CSP

The auditory faculty, the perception of sound by the ear.
NCI

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orchitida

Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD.
MSH

inflammation of one or both testis.
CSP

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hemoglobinurická horečka

A complication of MALARIA, FALCIPARUM characterized by the passage of dark red to black urine.
MSH

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porodní báby

A person (usually female) helping a woman deliver a baby. Responsibilities vary locally, ranging from a mere optional assistant to a full required participant, responsible for (normal) births and pre- and post-natal care for both mother and baby.


HL7V3.0

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Sciuridae

A family of the order Rodentia which contains 49 genera. Some of the more common genera are MARMOTA, which includes the marmot and woodchuck; Sciurus, the gray squirrel, S. carolinensis, and the fox squirrel, S. niger; Tamias, the eastern and western chipmunk; and Tamiasciurus, the red squirrel. The flying squirrels, except the scaly-tailed Anomaluridae, also belong to this family.
MSH

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léky – antagonismus

Phenomena and pharmaceutics of compounds that inhibit the function of agonists (DRUG AGONISM) and inverse agonists (DRUG INVERSE AGONISM) for a specific receptor. On their own, antagonists produce no effect by themselves to a receptor, and are said to have neither intrinsic activity nor efficacy.
MSH

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srdce – defekty septa

Abnormalities in any part of the HEART SEPTUM resulting in abnormal communication between the left and the right chambers of the heart. The abnormal blood flow inside the heart may be caused by defects in the ATRIAL SEPTUM, the VENTRICULAR SEPTUM, or both.
MSH

defects in the cardiac septa, resulting in abnormal communications between the opposite chambers of the heart that exist at, and usually before, birth regardless of their causation.
CSP

A congenital disorder characterized by the presence of an abnormal communication between the atria or the ventricles of the heart due to defects in the cardiac septum.
NCI

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orgasmus

The crisis of sexual excitement in either humans or animals.
MSH

The height of sexual excitement, consisting of a series of involuntary contractions of the muscles of the genitals, lower pelvis, and anus, accompanied by strong feelings of pleasure.
NCI

The final part of the sex act, which involves contraction of sexual organs and a sudden release of endorphins, leading to a feeling of pleasure. In males, orgasm usually occurs with release of semen.
NCI

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krev

The body fluid that circulates in the vascular system (BLOOD VESSELS). Whole blood includes PLASMA and BLOOD CELLS.
MSH

Body substance which consists of plasma and blood cells
UWDA

fluid that circulates through the heart, arteries, capillaries and veins, carrying nutriment and oxygen to and waste from the body cells; it consists of plasma, containing microscopically visible formed elements of the blood; erythrocytes; leukocytes; and blood platelets.
CSP

Portion of body substance which consists of plasma and blood cells.
FMA

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vedlejší histokompatibilní lokusy

Genetic loci responsible for the encoding of histocompatibility antigens other than those encoded by the MAJOR HISTOCOMPATIBILITY COMPLEX. The antigens encoded by these genes are often responsible for graft rejection in cases where histocompatibility has been established by standard tests. The location of some of these loci on the X and Y chromosomes explains why grafts from males to females may be rejected while grafts from females to males are accepted. In the mouse roughly 30 minor histocompatibility loci have been recognized, comprising more than 500 genes.
MSH

genetic loci responsible for the coding of histocompatibility antigens other than those coded by the major histocompatibility complex.
CSP

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