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Nevada

A state in the western United States. Its capital is Carson City.
NCI

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kulturní asimilace

Process of cultural change in which one group or members of a group assimilate various cultural patterns from another.
MSH

The process of adopting the traits or social patterns of a different population group.
NCI

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hypochondrie

Preoccupation with the fear of having, or the idea that one has, a serious disease based on the person`s misinterpretation of bodily symptoms. (APA, DSM-IV)
MSH

preoccupation with the fear of having, or the idea that one has, a serious disease based on the person`s misinterpretation of bodily symptoms.
CSP

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Churgův-Straussové syndrom

Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.
MSH

An autoimmune necrotizing vasculitis with the formation of granulomas. It is a pulmonary and systemic vasculitis associated with eosinophilia.
NCI

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epoprostenol

A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
MSH

prostaglandin synthesized by the vascular endothelium; potent inhibitor of platelet aggregation and powerful vasodilator.
CSP

An oral prostacyclin and a metabolite of arachidonic acid with antihypertensive and platelet inhibitory properties. Epoprostenol binds to prostacyclin receptors on platelet surfaces, subsequently activating platelet membrane adenyl cyclase and resulting in increased cAMP levels. The elevated cAMP triggers signal transduction that leads to vasodilations. In addition, this agent also functions as an antagonist of thromboxane A2, thereby resulting in direct vasodilation of pulmonary and systemic arterial vascular beds, and inhibition of platelet aggregation.
NCI

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nikotin

Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
MSH

very poisonous alkaloid; the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission; nicotine is important medically because of its presence in tobacco smoke, and is also used as an insecticide.
CSP

An addictive, poisonous chemical found in tobacco. It can also be made in the laboratory. When it enters the body, nicotine causes an increased heart rate and use of oxygen by the heart, and a sense of well-being and relaxation. It is also used as an insecticide.
NCI

A plant alkaloid, found in the tobacco plant, and addictive central nervous system (CNS) stimulant that causes either ganglionic stimulation in low doses or ganglionic blockage in high doses. Nicotine acts as an agonist at the nicotinic cholinergic receptors in the autonomic ganglia, at neuromuscular junctions, and in the adrenal medulla and the brain. Nicotine`s CNS-stimulating activities may be mediated through the release of several neurotransmitters, including acetylcholine, beta-endorphin, dopamine, norepinephrine, serotonin, and ACTH. As a result, peripheral vasoconstriction, tachycardia, and elevated blood pressure may be observed with nicotine intake. This agent may also stimulate the chemoreceptor trigger zone, thereby inducing nausea and vomiting. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42243&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42243&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C691″ NCI Thesaurus)
PDQ

A plant alkaloid, found in the tobacco plant, and addictive central nervous system (CNS) stimulant that causes either ganglionic stimulation in low doses or ganglionic blockage in high doses. Nicotine acts as an agonist at the nicotinic cholinergic receptors in the autonomic ganglia, at neuromuscular junctions, and in the adrenal medulla and the brain. Nicotine`s CNS-stimulating activities may be mediated through the release of several neurotransmitters, including acetylcholine, beta-endorphin, dopamine, norepinephrine, serotonin, and ACTH. As a result, peripheral vasoconstriction, tachycardia, and elevated blood pressure may be observed with nicotine intake. This agent may also stimulate the chemoreceptor trigger zone, thereby inducing nausea and vomiting.
NCI

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acetyl-CoA-karboxylasa

A carboxylating enzyme that catalyzes the conversion of ATP, acetyl-CoA, and HCO3- to ADP, orthophosphate, and malonyl-CoA. It is a biotinyl-protein that also catalyzes transcarboxylation. The plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA (From Enzyme Nomenclature, 1992) EC 6.4.1.2.
MSH

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systém hypotalamus-hypofýza

A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.
MSH

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cisplatina

An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
MSH

inorganic, water soluble platinum complex; radiation sensitizing agent.
CSP

A drug used to treat many types of cancer. Cisplatin contains the metal platinum. It kills cancer cells by damaging their DNA and stopping them from dividing. Cisplatin is a type of alkylating agent.
NCI

An inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39515&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39515&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C376″ NCI Thesaurus)
PDQ

An inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. (NCI04)
NCI

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proteinmethyltransferasy

Enzymes that catalyze the methylation of amino acids after their incorporation into a polypeptide chain. S-Adenosyl-L-methionine acts as the methylating agent. EC 2.1.1.
MSH

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nitrazepam

A benzodiazepine derivative used as an anticonvulsant and hypnotic.
MSH

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kyselá fosfatasa

An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.
MSH

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Island

A country in Northern Europe, island between the Greenland Sea and the North Atlantic Ocean, northwest of the UK. (NCI)
NCI

A country in Northern Europe, island between the Greenland Sea and the North Atlantic Ocean, northwest of the UK. (CIA World Factbook 2002)
NCI

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klemastin

A histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
MSH

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protozoální infekce zvířat

Infections with unicellular organisms formerly members of the subkingdom Protozoa. The infections may be experimental or veterinary.
MSH

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nitroreduktasy

Enzymes which reduce nitro groups (NITRO COMPOUNDS) and other nitrogenous compounds.
MSH

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akriflavin

3,6-Diamino-10-methylacridinium chloride mixt. with 3,6-acridinediamine. Fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.
MSH

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os ilium

The broad, dorsal, upper, and widest of the three principal bones composing either half of the pelvis. (NCI)
NCI

The uppermost and widest part of the hip bone
CHV

The broad, dorsal, upper, and widest of the three principal bones composing either half of the pelvis.
NCI

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klonixin

Anti-inflammatory analgesic.
MSH

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pseudopodia

A dynamic actin-rich extension of the surface of an animal cell used for locomotion or prehension of food.
MSH

A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding. [ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

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neodontogenní cysty

Cysts formed from epithelial inclusions in the lines of fusion of the embryonic processes which form the jaws. They include nasopalatine or incisive canal cyst, incisive papilla cyst, globulomaxillary cyst, median palatal cyst, median alveolar cyst, median mandibular cyst, and nasoalveolar cyst.
MSH

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aktivační analýza

A method of chemical analysis based on the detection of characteristic radionuclides following a nuclear bombardment. It is also known as radioactivity analysis. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
MSH

chemical analytic method based on the detection of characteristic radionuclides following a nuclear bombardment.
CSP

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imunita získaná od matky

Resistance to a disease-causing agent induced by the introduction of maternal immunity into the fetus by transplacental transfer or into the neonate through colostrum and milk.
MSH

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kobalt – isotopy

Stable cobalt atoms that have the same atomic number as the element cobalt, but differ in atomic weight. Co-59 is a stable cobalt isotope.
MSH

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psychologie

The science dealing with the study of mental processes and behavior in man and animals.
MSH

study of mental and behavioral phenomena in individuals and groups; human and nonhuman species are included.
CSP

The science dealing with the study of mental processes and behavior in man and animals. (MeSH)
NCI

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viry adenoasociované

A genus of the family PARVOVIRIDAE, subfamily PARVOVIRINAE, which are dependent on a coinfection with helper adenoviruses or herpesviruses for their efficient replication. The type species is Adeno-associated virus 2.
MSH

replication is dependent on a helper adenovirus; multiplies in cells which support adenovirus replication in many species of host.
CSP

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imunoglobuliny – těžké řetězce

A protein complex that consists of two heavy chains (gamma, alpha, delta, epsilon or mu). The larger of the two immunoglobulin chain types determines the immunoglobulin class (G, A, D, E or M, respectively). The heavy chain molecules exhibit the same structure and composition, which consists of constant, variable, and hypervariable regions.
NCI

The largest of polypeptide chains comprising immunoglobulins. They contain 450 to 600 amino acid residues per chain, and have molecular weights of 51-72 kDa.
MSH

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láčkovci – jedy

Venoms from jellyfish; CORALS; SEA ANEMONES; etc. They contain hemo-, cardio-, dermo- , and neuro-toxic substances and probably ENZYMES. They include palytoxin, sarcophine, and anthopleurine.
MSH

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psychoterapie racionálně emotivní

The replacement of illogical and unrealistic ideas with more realistic and adaptive ones through direct intervention and confrontation by the therapist.
MSH

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Adenoviridae – infekce

Virus diseases caused by the ADENOVIRIDAE.
MSH

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