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larynx – perichondritida

Inflammation of LARYNGEAL CARTILAGES, usually due to infections.
MSH

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cisplatina

An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
MSH

inorganic, water soluble platinum complex; radiation sensitizing agent.
CSP

A drug used to treat many types of cancer. Cisplatin contains the metal platinum. It kills cancer cells by damaging their DNA and stopping them from dividing. Cisplatin is a type of alkylating agent.
NCI

An inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39515&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39515&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C376″ NCI Thesaurus)
PDQ

An inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. (NCI04)
NCI

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thebain

A drug that is derived from opium, which contains from 0.3-1.5% thebaine depending on its origin. It produces strychnine-like convulsions rather than narcosis. It may be habit-forming and is a controlled substance (opiate) listed in the U.S. Code of Federal Regulations, Title 21 Part 1308.12 (1985). (From Merck Index, 11th ed)
MSH

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železité sloučeniny

Inorganic or organic compounds containing trivalent iron.
MSH

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posttraumatická bolest hlavy

Secondary headache attributed to TRAUMA of the HEAD and/or the NECK.
MSH

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Lupus erythematosus buňky

LE Cells: mature neutrophils with an inclusion of homogeneous staining degenerated nucleoprotein and antibody to nucleoprotein. They suggest SLE but are found in many diseases. They are prepared in vitro by mechanical disruption of blood followed by incubation to allow phagocytosis of nuclear material.
AIR

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klemastin

A histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
MSH

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thiadiaziny

6-membered aromatic ring structure with 2 nitrogen and 1 sulfur heteroatoms.
CSP

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fétus – monitorování

Physiologic or biochemical monitoring of the fetus. It is usually done during LABOR, OBSTETRIC and may be performed in conjunction with the monitoring of uterine activity. It may also be performed prenatally as when the mother is undergoing surgery.
MSH

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pralidoximové sloučeniny

Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.
MSH

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zákonodárství stomatologické

Laws and regulations pertaining to the field of dentistry, proposed for enactment or recently enacted by a legislative body.
MSH

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klonixin

Anti-inflammatory analgesic.
MSH

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thioinosin

Sulfhydryl analog of INOSINE that inhibits nucleoside transport across erythrocyte plasma membranes, and has immunosuppressive properties. It has been used similarly to MERCAPTOPURINE in the treatment of leukemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p503)
MSH

A sulfhydryl analog of inosine and an antimetabolite with potential antineoplastic and immunosuppressive properties. Thioinosine interferes with de novo purine synthesis and perturbs the pool of nucleotides necessary for DNA replication. As a result, this agent inhibits DNA synthesis, blocks cellular proliferation and induces apoptosis.
NCI

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fibrom

A benign tumor of fibrous or fully developed connective tissue.
MSH

benign tumor of fibrous or fully developed connective tissue.
CSP

A benign neoplasm arising from the fibrous tissues. It is characterized by the presence of spindle-shaped fibroblasts.
NCI

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těhotenství udržované

Physiological mechanisms that sustain the state of PREGNANCY.
MSH

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čočka oční

A transparent, biconvex structure of the EYE, enclosed in a capsule and situated behind the IRIS and in front of the vitreous humor (VITREOUS BODY). It is slightly overlapped at its margin by the ciliary processes. Adaptation by the CILIARY BODY is crucial for OCULAR ACCOMMODATION.
MSH

transparent biconvex body of the eye situated between the posterior chamber and the vitreous body, constituting part of the refracting mechanism of the eye.
CSP

A biconvex transparent structure of the eye through which light is focused on the retina. The lens sits behind the iris and is supported by the zonule, which connects it to the ciliary body. The lens is an avascular structure. (NCI)
NCI

A clear disk that focuses light, as in a camera or microscope. In the eye, the lens is a clear, curved structure at the front of the eye behind the pupil. It focuses light rays that enter the eye through the pupil, making an image on the retina (light-sensitive layers of nerve tissue at the back of the eye).
NCI

A biconvex transparent structure of the eye through which light is focused on the retina. The lens sits behind the iris and is supported by the zonule, which connects it to the ciliary body. The lens is an avascular structure.
NCI

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kobalt – isotopy

Stable cobalt atoms that have the same atomic number as the element cobalt, but differ in atomic weight. Co-59 is a stable cobalt isotope.
MSH

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torakoskopie

Endoscopic examination, therapy or surgery of the pleural cavity.
MSH

Examination of the inside of the chest, using a thoracoscope. A thoracoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a tool to remove tissue to be checked under a microscope for signs of disease.
NCI

Endoscopic examination of the thoracic cavity.
NCI

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financování organizované

All organized methods of funding.
MSH

all organized methods of funding by federal, state, and local agencies, as well as private organizations.
CSP

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síňové extrasystoly

A type of cardiac arrhythmia with premature atrial contractions or beats caused by signals originating from ectopic atrial sites. The ectopic signals may or may not conduct to the HEART VENTRICLES. Atrial premature complexes are characterized by premature P waves on ECG which are different in configuration from the P waves generated by the normal pacemaker complex in the SINOATRIAL NODE.
MSH

Ectopic impulses originating in the atria.
NCI

Ectopic impulses originating in the atria. (NCI)
NCI

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Leuconostoc

A genus of gram-positive, facultatively anaerobic bacteria whose growth is dependent on the presence of a fermentable carbohydrate. It is nonpathogenic to plants and animals, including humans.
MSH

A genus of gram-positive, nonmotile cocci in the phylum Firmicutes.
NCI

Any bacteria that is not assigned to the species level but can be assigned to the Leuconostoc genus level.
NCI

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láčkovci – jedy

Venoms from jellyfish; CORALS; SEA ANEMONES; etc. They contain hemo-, cardio-, dermo- , and neuro-toxic substances and probably ENZYMES. They include palytoxin, sarcophine, and anthopleurine.
MSH

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1-methyl-4-fenylpyridinium

An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.
MSH

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noha plochá

A condition in which one or more of the arches of the foot have flattened out.
MSH

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Primaquine Phosphate

The phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the properties of protozoal DNA. This agent eliminates tissue (exo-erythrocytic) malarial infection, preventing the development of the erythrocytic forms of the parasite which are responsible for relapses in Plasmodium vivax and ovale malaria. Primaquine is active against late hepatic stages (hypnozoites, schizonts).
NCI

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leukémie radiační

Leukemia produced by exposure to IONIZING RADIATION or NON-IONIZING RADIATION.
MSH

radiation induced progressive, malignant disease of the blood forming organs.
CSP

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kolifágy

Viruses whose host is Escherichia coli.
MSH

a phage isolated from E. coli.
CSP

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24,25-dihydroxyvitamin D 3

A physiologically active metabolite of VITAMIN D. The compound is involved in the regulation of calcium metabolism, alkaline phosphatase activity, and enhances the calcemic effect of CALCITRIOL.
MSH

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tekutiny a sekrety tělesné

Liquid substances produced by living organisms to fulfill specific functions or excreted as waste.
MSH

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prochlorperazin

A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
MSH

phenothiazine derivative used chiefly as an antiemetic.
CSP

A drug used to prevent or reduce nausea and vomiting. It belongs to the family of drugs called antiemetics.
NCI

A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39564&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39564&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C774″ NCI Thesaurus)
PDQ

A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. (NCI04)
NCI

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