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pralidoximové sloučeniny

Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.
MSH

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faktor Va

Activated form of factor V. It is an essential cofactor for the activation of prothrombin catalyzed by factor Xa.
MSH

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Benigní novotvar tlustého střeva

A non-metastasizing neoplasm arising from the wall of the colon.
NCI

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thioinosin

Sulfhydryl analog of INOSINE that inhibits nucleoside transport across erythrocyte plasma membranes, and has immunosuppressive properties. It has been used similarly to MERCAPTOPURINE in the treatment of leukemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p503)
MSH

A sulfhydryl analog of inosine and an antimetabolite with potential antineoplastic and immunosuppressive properties. Thioinosine interferes with de novo purine synthesis and perturbs the pool of nucleotides necessary for DNA replication. As a result, this agent inhibits DNA synthesis, blocks cellular proliferation and induces apoptosis.
NCI

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kuru

A prion disease found exclusively among the Fore linguistic group natives of the highlands of NEW GUINEA. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773)
MSH

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diminazen

An effective trypanocidal agent.
MSH

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těhotenství udržované

Physiological mechanisms that sustain the state of PREGNANCY.
MSH

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rodina – charakteristika

Size and composition of the family.
MSH

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benzofenoneidum

An aniline dye used as a disinfectant and an antiseptic agent. It is weakly fluorescing and binds specifically to certain proteins.
MSH

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torakoskopie

Endoscopic examination, therapy or surgery of the pleural cavity.
MSH

Examination of the inside of the chest, using a thoracoscope. A thoracoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a tool to remove tissue to be checked under a microscope for signs of disease.
NCI

Endoscopic examination of the thoracic cavity.
NCI

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labyrintitida

Inflammation of the inner ear (LABYRINTH).
MSH

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Diphtheria-Tetanus-Pertussis Vaccine

diphtheria, tetanus toxoids and pertussis vaccine


HL7V3.0

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síňové extrasystoly

A type of cardiac arrhythmia with premature atrial contractions or beats caused by signals originating from ectopic atrial sites. The ectopic signals may or may not conduct to the HEART VENTRICLES. Atrial premature complexes are characterized by premature P waves on ECG which are different in configuration from the P waves generated by the normal pacemaker complex in the SINOATRIAL NODE.
MSH

Ectopic impulses originating in the atria.
NCI

Ectopic impulses originating in the atria. (NCI)
NCI

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únava duševní

A condition of low alertness or cognitive impairment, usually associated with prolonged mental activities or stress.
MSH

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beta-Atrial Natriuretic Peptide

An antiparallel dimer of alpha-ANP with the chains linked by 7-23` and 7`-23 disulfide bonds.
MSH

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1-methyl-4-fenylpyridinium

An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.
MSH

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zchromnutí zvířat

A departure from the normal gait in animals.
MSH

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nemoc – zdroje

Animate or inanimate sources which normally harbor disease-causing organisms and thus serve as potential sources of disease outbreaks. Reservoirs are distinguished from vectors (DISEASE VECTORS) and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks.
MSH

animate or inanimate sources which harbor disease-causing organisms and thus serve as potential sources of disease outbreaks; reservoirs should be distinguished from vectors and carriers, which are agents of disease transmission rather than continuing sources of potential disease outbreaks.
CSP

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Primaquine Phosphate

The phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the properties of protozoal DNA. This agent eliminates tissue (exo-erythrocytic) malarial infection, preventing the development of the erythrocytic forms of the parasite which are responsible for relapses in Plasmodium vivax and ovale malaria. Primaquine is active against late hepatic stages (hypnozoites, schizonts).
NCI

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panleukopenie koček

A highly contagious DNA virus infection of the cat family, characterized by fever, enteritis and bone marrow changes. It is also called feline ataxia, feline agranulocytosis, feline infectious enteritis, cat fever, cat plague, and show fever. It is caused by FELINE PANLEUKOPENIA VIRUS or the closely related MINK ENTERITIS VIRUS or CANINE PARVOVIRUS.
MSH

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bibliografie lékařská

A list of works, documents, and other publications on medical subjects and topics of interest to the field of medicine.
MSH

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24,25-dihydroxyvitamin D 3

A physiologically active metabolite of VITAMIN D. The compound is involved in the regulation of calcium metabolism, alkaline phosphatase activity, and enhances the calcemic effect of CALCITRIOL.
MSH

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larynx – perichondritida

Inflammation of LARYNGEAL CARTILAGES, usually due to infections.
MSH

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Suxamethonium Chloride

The chloride salt form of succinylcholine, a quaternary ammonium compound and depolarizing agent with short-term muscle relaxant properties. Succinylcholine chloride binds to nicotinic receptors at the neuromuscular junction and opening the ligand-gated channels in the same way as acetylcholine, resulting in depolarization and inhibition of neuromuscular transmission. Depolarization may be prolonged due to succinylcholine`s resistance to acetylcholinesterases thereby leading to disorganized muscle contraction followed by skeletal muscle relaxation and flaccid paralysis.
NCI

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prochlorperazin

A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
MSH

phenothiazine derivative used chiefly as an antiemetic.
CSP

A drug used to prevent or reduce nausea and vomiting. It belongs to the family of drugs called antiemetics.
NCI

A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39564&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39564&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C774″ NCI Thesaurus)
PDQ

A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. (NCI04)
NCI

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železité sloučeniny

Inorganic or organic compounds containing trivalent iron.
MSH

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vazba kompetitivní

The interaction of two or more substrates or ligands with the same binding site. The displacement of one by the other is used in quantitative and selective affinity measurements.
MSH

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androstan-3,17-diol

The unspecified form of the steroid, normally a major metabolite of TESTOSTERONE with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.
MSH

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Lupus erythematosus buňky

LE Cells: mature neutrophils with an inclusion of homogeneous staining degenerated nucleoprotein and antibody to nucleoprotein. They suggest SLE but are found in many diseases. They are prepared in vitro by mechanical disruption of blood followed by incubation to allow phagocytosis of nuclear material.
AIR

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DNA řízená DNA-polymerasa

DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair. EC 2.7.7.7.
MSH

Nucleotidyltransferases that catalyze the addition of deoxyribonucleotide residues to the end of a DNA. EC 2.7.7.7 or EC 2.7.7.49
NCI

Catalyses DNA-template-directed extension of the 3`- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA. (IUBMB Enzyme Nomenclature)
NCI

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