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karcinom intraduktální neinfiltrující

A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma.
MSH

A noninvasive condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not spread outside the duct to other tissues in the breast. In some cases, ductal carcinoma in situ may become invasive cancer and spread to other tissues, although it is not known at this time how to predict which lesions will become invasive.
NCI

A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.
NCI

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plíce – eozinofilie

A condition characterized by infiltration of the lung with EOSINOPHILS due to inflammation or other disease processes. Major eosinophilic lung diseases are the eosinophilic pneumonias caused by infections, allergens, or toxic agents.
MSH

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NADPH-dehydrogenasa

A flavoprotein that reversibly oxidizes NADPH to NADP and a reduced acceptor. EC 1.6.99.1.
MSH

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mladiství umístění v ústavech

An adolescent who is receiving long-term in-patient services or who resides in an institutional setting.
MSH

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homosexualita

The sexual attraction or relationship between members of the same SEX.
MSH

sexual attraction or relationship between members of the same sex.
CSP

A sexual attraction to members of the same sex. (WordNet)
NCI

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kardiotonika

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
MSH

agents that have a strengthening effect on the heart or that can increase cardiac output.
CSP

any agent having a favorable effect on the function of the heart.
NCI

An agent that prevents damage to the heart, thereby protecting myocardial function.
NCI

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purinnukleosidy

Purines with a RIBOSE attached that can be phosphorylated to PURINE NUCLEOTIDES.
MSH

condensation product of a purine base plus a sugar.
CSP

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naftaleny

Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.
MSH

two-ring crystalline aromatic hydrocarbons isolated from coal tar; used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, and preservatives.
CSP

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dospělí

A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.
MSH

A human who has reached reproductive age.
NCI

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nemocnice – restrukturalizace

Reorganization of the hospital corporate structure.
MSH

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KARPIOKO KANALEKO SINDROMEA

Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)
MSH

entrapment of the median nerve in the carpal tunnel, which is formed by the flexor retinaculum and the carpal bones; this syndrome may be associated with repetitive occupational trauma, wrist injuries, amyloid neuropathies, rheumatoid arthritis, acromegaly, pregnancy, and other conditions; symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally; impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur.
CSP

You`re working at your desk, trying to ignore the tingling or numbness you`ve had for some time in your hand and wrist. Suddenly, a sharp, piercing pain shoots through the wrist and up your arm. Just a passing cramp? More likely you have carpal tunnel syndrome.

The carpal tunnel is a narrow passageway of ligament and bones at the base of your hand. It contains nerve and tendons. Sometimes, thickening from irritated tendons or other swelling narrows the tunnel and causes the nerve to be compressed. Symptoms usually start gradually. As they worsen, grasping objects can become difficult.

What causes the problem? Some people have smaller carpal tunnels than other people do. Other causes include performing assembly line work, wrist injury, or swelling due to certain diseases, such as rheumatoid arthritis. Women are three times more likely to have carpal tunnel syndrome than men. Treatment includes resting your hand, splints, pain and anti-inflammatory medicines, and surgery.

NIH: National Institute of Neurological Disorders and Stroke


MEDLINEPLUS

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pyonefróza

Distention of KIDNEY with the presence of PUS and suppurative destruction of the renal parenchyma. It is often associated with renal obstruction and can lead to total or nearly total loss of renal function.
MSH

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Informační centrum pro národní zdravotnické plánování (USA)

A center in the HEALTH RESOURCES ADMINISTRATION Division of Planning Methods and Technology which provides access to current information on health planning and resources development.
MSH

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africká choroba koní

An insect-borne reovirus infection of horses, mules and donkeys in Africa and the Middle East; characterized by pulmonary edema, cardiac involvement, and edema of the head and neck.
MSH

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nemocnice městské

Hospitals located in metropolitan areas.
MSH

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katatonie

A neuropsychiatric disorder characterized by one or more of the following essential features: immobility, mutism, negativism (active or passive refusal to follow commands), mannerisms, stereotypies, posturing, grimacing, excitement, echolalia, echopraxia, muscular rigidity, and stupor; sometimes punctuated by sudden violent outbursts, panic, or hallucinations. This condition may be associated with psychiatric illnesses (e.g., SCHIZOPHRENIA; MOOD DISORDERS) or organic disorders (NEUROLEPTIC MALIGNANT SYNDROME; ENCEPHALITIS, etc.). (From DSM-IV, 4th ed, 1994; APA, Thesaurus of Psychological Index Terms, 1994)
MSH

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pyrogalol

A trihydroxybenzene or dihydroxy phenol that can be prepared by heating GALLIC ACID.
MSH

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Necturus

A genus of the Proteidae family with five recognized species, which inhabit the Atlantic and Gulf drainages.
MSH

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zemědělství

The science of soil cultivation, crop production, and livestock raising.
MSH

the science, art, or practice of cultivating the soil, producing crops, and raising livestock and in varying degrees the preparation and marketing of the resulting products.
CSP

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humanismus

An ethical system which emphasizes human values and the personal worth of each individual, as well as concern for the dignity and freedom of humankind.
MSH

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kauzalgie

A complex regional pain syndrome characterized by burning pain and marked sensitivity to touch (HYPERESTHESIA) in the distribution of an injured peripheral nerve. Autonomic dysfunction in the form of sudomotor (i.e., sympathetic innervation to sweat glands), vasomotor, and trophic skin changes may also occur. (Adams et al., Principles of Neurology, 6th ed, p1359)
MSH

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šarlatánství

The fraudulent misrepresentation of the diagnosis and treatment of disease.
MSH

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nádorové proteiny

Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (TUMOR MARKERS, BIOLOGICAL) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm.
MSH

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Aljaška

constituent state of the United States of America; it lies at the extreme northwest of the North American continent and is the largest peninsula in the Western Hemisphere.
CSP

A state in the far northwestern United States. Its capital is Juneau.
NCI

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uhlovodíky aromatické

Organic compounds containing carbon and hydrogen in the form of an unsaturated, usually hexagonal ring structure. The compounds can be single ring, or double, triple, or multiple fused rings.
MSH

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cefuroxim

Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
MSH

A semisynthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin with antibacterial activity. Cefuroxime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
NCI

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chinuklidinylbenzilan

A high-affinity muscarinic antagonist commonly used as a tool in animal and tissue studies.
MSH

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nefrektomie

Excision of a kidney. (Dorland, 28th ed)
MSH

surgical removal of a kidney.
CSP

Surgery to remove a kidney or part of a kidney. In a partial nephrectomy, part of one kidney or a tumor is removed, but not an entire kidney. In a simple nephrectomy, one kidney is removed. In a radical nephrectomy, an entire kidney, nearby adrenal gland and lymph nodes, and other surrounding tissue are removed. In a bilateral nephrectomy, both kidneys are removed.
NCI

A surgical procedure to completely or partially remove a kidney. With a complete nephrectomy, the attached adrenal gland, perinephric fat, and regional lymph nodes are often removed as well. With a partial nephrectomy, the removed tissue contains the tumor and a rim of normal renal parenchyma only.
NCI

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aldehydy

organic compounds containing a carbonyl group in the form -CHO.
CSP

A type of chemical substance made from alcohol. Aldehydes are found in essential oils (scented liquid taken from plants).
NCI

Any organic compound containing a formyl (-CHO) group. Its functional group, with the structure R-CHO, consists of a carbonyl center bonded to hydrogen and an R group. Traces of various aldehydes are found in essential oils and often contribute to their odors.
NCI

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kyseliny hydroxamové

A class of weak acids with the general formula R-CONHOH.
MSH

A group of weak acids with the general chemical formula RC(=O)N(R`)OH and antineoplastic and antimicrobial activities. Hydroxamic acids covalently bind to the zinc(II) ion in the active sites of matrix metalloproteinases (MMP), thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. (NCI04)
NCI

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