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Antazoline Phosphate

The phosphate salt of antazoline, an ethylenediamine derivative with histamine H1 antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor and prevents the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, gastrointestinal and bronchial smooth muscles. These histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Antazoline is used to provide symptomatic relieve of allergic symptoms.
NCI

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mezonefrom

A rare tumor of the female genital tract, most often the ovary, formerly considered to be derived from mesonephric rests. Two varieties are recognized: (1) clear cell carcinoma, so called because of its histologic resemblance to renal cell carcinoma, and now considered to be of muellerian duct derivation and (2) an embryonal tumor (called also ENDODERMAL SINUS TUMOR and yolk sac tumor), occurring chiefly in children. The latter variety may also arise in the testis. (Dorland, 27th ed)
MSH

An adenocarcinoma of the cervix or the vagina arising from mesonephric remnants.
NCI

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ampicilin

semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
CSP

A broad-spectrum, semi-synthetic, beta-lactam penicillin antibiotic with bactericidal activity. Ampicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis. Ampicillin is stable against hydrolysis by a variety of beta-lactamases, therefore, can be used in wide range of gram-positive and -negative infections.
NCI

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Grónsko

An island between the Arctic Ocean and the North Atlantic Ocean, northeast of Canada. (NCI)
NCI

An island between the Arctic Ocean and the North Atlantic Ocean, northeast of Canada. (CIA World Factbook 2002)
NCI

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dávkové mechanismy

Processes or methods of reimbursement for services rendered or equipment.
MSH

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kuldoskopie

Endoscopic examination, therapy or surgery of the female pelvic viscera by means of an endoscope introduced into the pelvic cavity through the posterior vaginal fornix.
MSH

Endoscopic examination of a woman`s pelvic organs using a culdoscope inserted through the vagina.
NCI

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protivředové látky

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
MSH

class of agents, exclusive of the antibacterial agents, used to treat ulcers in the stomach and the upper part of the small intestine.
CSP

Natural or synthetic Anti-ulcer Agents relieve and reduce the symptoms of ulcers in the stomach and upper small intestine, systemically and locally, by reducing gastric secretion (proton pump inhibitors), neutralizing hyperacidity (alkalinizing agents), or improving healing and protecting the mucosa (sucralfate). Recurrent gastric and duodenal ulcers caused by Helicobacter pylori infections are treated with antibiotic therapy.
NCI

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Squamous metaplasia

A morphologic finding indicating the transformation of glandular or transitional epithelial cells to, usually, mature squamous epithelial cells. Representative examples include squamous metaplasia of bronchial epithelium, cervix, urinary bladder, and prostate gland.
NCI

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analeptika

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.
MSH

Any agent capable of having a stimulating effect on the central nervous system (CNS).
NCI

loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation.
CSP

In medicine, a family of drugs used to treat depression, attention-deficit disorder (a common disorder in which children are inattentive, impulsive, and/or over-active), and narcolepsy (a sleep disorder that causes uncontrollable sleepiness). Stimulants increase brain activity, alertness, attention, and energy. They also raise blood pressure and increase heart rate and breathing rate.
NCI

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guanindeaminasa

An enzyme that catalyzes the deamination of guanine to form xanthine. EC 3.5.4.3.
MSH

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ledviny – vrozené poruchy tubulárního transportu

Genetic defects in the selective or non-selective transport functions of the KIDNEY TUBULES.
MSH

genetically determined disorders of the reabsorptive functions of the kidney with regard to specific nephron segments responsible for specific transport functions, classifiable by proximal nephron function, loop of Henle function, and distal nephron function; transport defects can be selective or nonselective.
CSP

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cyklandelát

A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia.
MSH

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antikodon

The sequential set of three nucleotides in TRANSFER RNA that interacts with its complement in MESSENGER RNA, the CODON, during translation in the ribosome.
MSH

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metergolin

A dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for MIGRAINE DISORDERS therapy.
MSH

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ankylostomiáza

Infection of humans or animals with hookworms of the genus ANCYLOSTOMA. Characteristics include anemia, dyspepsia, eosinophilia, and abdominal swelling.
MSH

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Romové

Ethnic group originating in India and entering Europe in the 14th or 15th century.
MSH

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metody výzkumu

Technique used in the laboratory for scientific research.
NCI

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Cyprinidae

A family of freshwater fish comprising the minnows or CARPS.
MSH

any of various freshwater fish of the family Cyprinidae.
CSP

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antigeny povrchové

Antigens on surfaces of cells, including infectious or foreign cells or viruses. They are usually protein-containing groups on cell membranes or walls and may be isolated.
MSH

antigens on surfaces of cells, including infectious or foreign cells or viruses; usually protein-containing groups on cell membranes or walls.
CSP

Antigens on surfaces of cells, including infectious or foreign cells or viruses. They are usually protein-containing groups on cell membranes or walls and may be isolated.
NCI

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methylcelulosa

Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.
MSH

methylester of cellulose; used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry and is used therapeutically as a bulk laxative.
CSP

The methyl ether of cellulose with laxative activity. Methylcellulose is not absorbed by the intestines and attracts large amounts of water into the colon, thereby increasing viscosity, producing a softer and bulkier stool and stimulating the constriction of intestinal smooth muscles.
NCI

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Hallervordenův-Spatzův syndrom

A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolescence. Clinical manifestations include progressive MUSCLE SPASTICITY; hyperreflexia; MUSCLE RIGIDITY; DYSTONIA; DYSARTHRIA; and intellectual deterioration which progresses to severe dementia over several years. (From Adams et al., Principles of Neurology, 6th ed, p972; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp972-929)
MSH

A rare autosomal recessive inherited disorder caused by mutations in the PANK2 gene. It is characterized by abnormal accumulation of iron in the basal ganglia. Signs and symptoms include progressive motor disturbances, muscle spasm and rigidity, dysarthria, mental deterioration, and behavioral changes.
NCI

A rare neuroaxonal dystrophy, histologically characterized by axonal spheroids, iron deposition, lewy body (LB)-like intraneuronal inclusions and neurofibrillary tangles.
NCI

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dýchací systém – infekce

Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases.
MSH

invasion and growth of microorganisms in the respiratory system; may be clinically inapparent or result in local cellular injury.
CSP

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cystinóza

A metabolic disease characterized by the defective transport of CYSTINE across the lysosomal membrane due to mutation of a membrane protein cystinosin. This results in cystine accumulation and crystallization in the cells causing widespread tissue damage. In the KIDNEY, nephropathic cystinosis is a common cause of RENAL FANCONI SYNDROME.
MSH

lysosomal storage disorders of unknown molecular defect, characterized by widespread deposition of cystine crystals in reticuloendothelial cells.
CSP

An autosomal recessive hereditary disorder characterized by defective transportation of cystine across the lysosomal membranes and systemic deposition of cystine crystals in the body. It is associated with slight increase of the plasma cystine, cystinuria, aminoaciduria, glycosuria, polyuria, hypophosphatemia, rickets, and renal tubular dysfunction. –2004
NCI

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antipyretika

agent that relieves or reduces fever.
CSP

Drugs that are used to reduce body temperature in fever.
MSH

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methylmočovinové sloučeniny

Urea compounds which are substituted with one or more methyl groups.
MSH

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tvrdost

The mechanical property of material that determines its resistance to force. HARDNESS TESTS measure this property.
MSH

quality of firmness produced by cohesion of the particles composing a substance, observed by its inflexibility or resistance to indentation or distortion.
CSP

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retina – perforace

Perforations through the whole thickness of the retina including the macula as the result of inflammation, trauma, degeneration, etc. The concept includes retinal breaks, tears, dialyses, and holes.
MSH

A usually small tearing of the retina occurring when the vitreous separates from the retina. It may lead to retinal detachment. Symptoms include flashes and floaters.
NCI

A disorder characterized by a small laceration of the retina, this occurs when the vitreous separates from the retina. Symptoms include flashes and floaters.
NCI

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cytodiagnostika

Diagnosis of the type and, when feasible, the cause of a pathologic process by means of microscopic study of cells in an exudate or other form of body fluid. (Stedman, 26th ed)
MSH

diagnosis of the type and, when feasible, the cause of a pathologic process by means of microscopic study of cells in an exudate or other form of body fluid.
CSP

A diagnostic test utilized to examine and define cellular anatomy or function. The test results are often used by a clinician to diagnose disease or disordered function.
NCI

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Boog, aorta-

The curved section of the aorta between the ascending and the descending tracts. The brachiocephalic, left common carotid and left subclavian arteries branch from the aorta at this section. (NCI)
NCI

The curved section of the aorta between the ascending and the descending tracts. The brachiocephalic, left common carotid and left subclavian arteries branch from the aorta at this section.
NCI

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myši transgenní

Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
MSH

A mouse whose genome has been altered by the inclusion of foreign genetic material. The technique involves microinjection of foreign DNA fragments into the nucleus of a fertilized egg. The inserted gene becomes integrated into every cell and tissue of the mouse.
NCI

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