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teleangiektazie

Permanent dilation of preexisting blood vessels (CAPILLARIES; ARTERIOLES; VENULES) creating small focal red lesions, most commonly in the skin or mucous membranes. It is characterized by the prominence of skin blood vessels, such as vascular spiders.
MSH

localized convolution and dilatation of a group of small blood vessels, leading to hemorrhage and angioma.
CSP

The permanent enlargement of blood vessels, causing redness in the skin or mucous membranes.
NCI

A disorder characterized by local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes.
NCI

a visibly dilated blood vessel on the skin
CHV

Local dilatation of small vessels resulting in red discoloration of the skin or mucous membranes.
NCI

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hyperlipoproteinémie typ V

A severe type of hyperlipidemia, sometimes familial, that is characterized by the elevation of both plasma CHYLOMICRONS and TRIGLYCERIDES contained in VERY-LOW-DENSITY LIPOPROTEINS. Type V hyperlipoproteinemia is often associated with DIABETES MELLITUS and is not caused by reduced LIPOPROTEIN LIPASE activity as in HYPERLIPOPROTEINEMIA TYPE I .
MSH

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polycythemia vera

A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
MSH

myeloproliferative disorder characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume; associated frequently with splenomegaly, leukocytosis, and thrombocythemia.
CSP

a condition that produces excessive red blood cells
CHV

A disease in which there are too many red blood cells in the bone marrow and blood, causing the blood to thicken. The number of white blood cells and platelets may also increase. The extra blood cells may collect in the spleen and cause it to become enlarged. They may also cause bleeding problems and make clots form in blood vessels.
NCI

A chronic myeloproliferative neoplasm characterized by an increased red blood cell production. Excessive proliferation of the myeloid lineage is observed as well. The major symptoms are related to hypertension or to vascular abnormalities caused by the increased red cell mass. The cause is unknown. With currently available treatment, the median survival exceeds 10 years. (WHO, 2001)
NCI

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vztah dávky záření a odpovědi

The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation.
MSH

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neurosekreční systémy

A system of neurons that has the specialized function to produce and secrete hormones, and that constitutes, in whole or in part, an endocrine organ or system.
MSH

organs, structures, or transmitter/receptor systems involved in communication between the nervous and endocrine systems.
CSP

Having to do with the interactions between the nervous system and the endocrine system. Neuroendocrine describes certain cells that release hormones into the blood in response to stimulation of the nervous system.
NCI

A system of neurosecretory neurons that release hormones to the circulatory system.
NCI

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biuret

Used as feed supplement for sheep and cattle since it is a good non-protein nitrogen source. In strongly alkaline solution biuret gives a violet color with copper sulfate.
MSH

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EPIKONDILITIS HUMERALA

A condition characterized by pain in or near the lateral humeral epicondyle or in the forearm extensor muscle mass as a result of unusual strain. It occurs in tennis players as well as housewives, artisans, and violinists.
MSH

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hypertrichóza

Excessive hair growth at inappropriate locations, such as on the extremities, the head, and the back. It is caused by genetic or acquired factors, and is an androgen-independent process. This concept does not include HIRSUTISM which is an androgen-dependent excess hair growth in WOMEN and CHILDREN.
MSH

Generalized or localized hair growth of abnormal length and density. It may be congenital or acquired (e.g., drug-induced).
NCI

A disorder characterized by hair density or length beyond the accepted limits of normal in a particular body region, for a particular age or race.
NCI

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polynukleotidligasy

Catalyze the joining of preformed ribonucleotides or deoxyribonucleotides in phosphodiester linkage during genetic processes. EC 6.5.1.
MSH

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léky – způsoby aplikace

The various ways of administering a drug or other chemical to a site in a patient or animal from where the chemical is absorbed into the blood and delivered to the target tissue.
MSH

various ways of administering a drug or other chemical to a site in a patient or animal from where the chemical is absorbed and delivered to the target tissue.
CSP

Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration. (ICH)
NCI

The course by which a substance was administered in order to reach the site of action in the body.
NCI

The path the administered medication takes to get into the body or into contact with the body.


HL7V3.0

Description:This describes which path the administered medication takes to get into the body or into contact with the body and constitutes part of thewhere (the other part being site – see below). It is theway in or the course the medication must take to get to its destination.

Note that a path is in no sense a description of afinal destination; it is a stylized description of the path taken. For example, an oral antibiotic may be used to treat a severe infection on a toe; the oral route is used to get the medicine to be able to reach and treat the infection in the toe. For some specific routes of administration there may be an incidental sense offinal destination, for example an ocular administration usually occurs when treatment of an eye condition is required. However, this is in no sense definitional: rectal administration of a medicine may be for a local effect (a steroid foam for treatment of colitis) or for a systemic effect (metronidazole for treatment of infection). The route of administration of a medicine should only be a description of the path taken and not the form.

Examples:

  • oral

  • rectal

  • intravenous (IV)

  • subcutaneous (SC)

  • intramuscular (IM)


HL7V3.0

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Newfoundland

An island in the Atlantic Ocean, off the east coast of Canada, constituting with Labrador on the mainland, a province of Canada. The name describing a land just discovered was recorded by John Cabot in 1497. (From Webster`s New Geographical Dictionary, 1988, p831 & Room, Brewer`s Dictionary of Names, 1992, p376)
MSH

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blefarospazmus

Excessive winking; tonic or clonic spasm of the orbicularis oculi muscle.
MSH

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TETANOAK

A disease caused by tetanospasmin, a powerful protein toxin produced by CLOSTRIDIUM TETANI. Tetanus usually occurs after an acute injury, such as a puncture wound or laceration. Generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia. Localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound. It may progress to the generalized form.
MSH

disease caused by tetanospasmin, a powerful protein toxin produced by Clostridium tetani; tetanus usually occurs after an acute injury, such as a puncture wound or laceration; generalized tetanus, the most common form, is characterized by tetanic muscular contractions and hyperreflexia; localized tetanus presents itself as a mild condition with manifestations restricted to muscles near the wound.
CSP

Tetanus is a serious illness caused by tetanus bacteria. The bacteria live in soil, saliva, dust and manure. The bacteria usually enter the body through a deep cut, like those you might get from cutting yourself with a knife or stepping on a nail.

The infection causes painful tightening of the muscles, usually all over the body. It can lead to "locking" of the jaw, which makes it impossible to open your mouth or swallow. If this happens, you could die of suffocation.

If you get tetanus, there is usually a long course of treatment. The tetanus vaccine can prevent tetanus but its protection does not last forever. Adults should get a tetanus shot, or booster, every 10 years. If you get a bad cut or burn, see your doctor–you may need a booster.


MEDLINEPLUS

A serious infectious disorder that follows wound contamination by the Gram-positive bacterium Clostridium tetani. The bacteria produce a neurotoxin called tetanospasmin, which causes muscle spasm in the jaw and other anatomic sites.
NCI

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hypofosfatázie

A genetic metabolic disorder resulting from serum and bone alkaline phosphatase deficiency leading to hypercalcemia, ethanolamine phosphatemia, and ethanolamine phosphaturia. Clinical manifestations include severe skeletal defects resembling vitamin D-resistant rickets, failure of the calvarium to calcify, dyspnea, cyanosis, vomiting, constipation, renal calcinosis, failure to thrive, disorders of movement, beading of the costochondral junction, and rachitic bone changes. (From Dorland, 27th ed)
MSH

genetic metabolic disorder resulting from serum and bone alkaline phosphatase deficiency leading to hypercalcemia, ethanolamine phosphatemia, and ethanolamine phosphaturia; manifestations include severe skeletal defects resembling vitamin D resistant rickets, failure of the calvarium to calcify, dyspnea, cyanosis, vomiting, constipation, renal calcinosis, failure to thrive, disorders of movement, beading of the costochondral junction, and rachitic bone changes.
CSP

A rare, serious metabolic disorder caused by mutations in the gene encoding tissue non-specific alkaline phosphatase (TNSALP) activity. It is characterized by low activity of TNSALP in the serum. The signs and symptoms vary significantly and include death in utero, failure to thrive, premature loss of deciduous teeth, early loss of the adult dentition, hypercalcemia, osteomalacia, skeletal defects, renal stones, and movement disorders.
NCI

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Apen

anthropoid apes, a family of primates that includes gorillas, orangutans, and chimpanzees; some are used in laboratory experiments because of their relationship to humans.
CSP

An obsolete name for a family of Primates consisting of three genera: Pongo (PONGO PYGMAEUS), Pan (PAN TROGLODYTES and PAN PANISCUS), and Gorilla (GORILLA GORILLA).
MSH

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léky – toxicita

Manifestations of the adverse effects of drugs administered therapeutically or in the course of diagnostic techniques. It does not include accidental or intentional poisoning for which specific headings are available.
MSH

An adverse effect of a drug used therapeutically or diagnostically.
NCI

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nimodipin

A calcium channel blockader with preferential cerebrovascular activity. It has marked cerebrovascular dilating effects and lowers blood pressure.
MSH

1,4 dihydropyridine; centrally acting calcium channel blocker used in the treatment of a wide range of disorders, including drug withdrawal, AIDS motor/cognitive disorder, and post cardiac surgery recovery.
CSP

Belongs to a family of drugs called calcium channel blockers. It is being investigated for use with anticancer drugs to prevent or overcome drug resistance and improve response to chemotherapy.
NCI

A dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine inhibits the transmembrane influx of calcium ions in response to depolarization in smooth muscle cells, thereby inhibiting vascular smooth muscle contraction and inducing vasodilatation. Nimodipine has a greater effect on cerebral arteries than on peripheral smooth muscle cells and myocardial cells, probably because this agent can cross the blood brain barrier due to its lipophilic nature. Furthermore, this agent also inhibits the drug efflux pump P-glycoprotein, which is overexpressed in some multi-drug resistant tumors, and may improve the efficacy of some antineoplastic agents. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41210&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41210&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C692″ NCI Thesaurus)
PDQ

A dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity. Nimodipine inhibits the transmembrane influx of calcium ions in response to depolarization in smooth muscle cells, thereby inhibiting vascular smooth muscle contraction and inducing vasodilatation. Nimodipine has a greater effect on cerebral arteries than on peripheral smooth muscle cells and myocardial cells, probably because this agent can cross the blood brain barrier due to its lipophilic nature. Furthermore, this agent also inhibits the drug efflux pump P-glycoprotein, which is overexpressed in some multi-drug resistant tumors, and may improve the efficacy of some antineoplastic agents.
NCI

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krevní tlak

PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
MSH

force exerted by the blood on the walls of the arteries and other vessels.
CSP

The pressure of the circulating blood against the walls of the blood vessels.
NCI

The force of circulating blood on the walls of the arteries. Blood pressure is taken using two measurements: systolic (measured when the heart beats, when blood pressure is at its highest) and diastolic (measured between heart beats, when blood pressure is at its lowest). Blood pressure is written with the systolic blood pressure first, followed by the diastolic blood pressure (for example 120/80).
NCI

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Texas

A state in the southern midwest United States. Its capital is Austin.
NCI

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hysterie

Historical term for a chronic, but fluctuating, disorder beginning in early life and characterized by recurrent and multiple somatic complaints not apparently due to physical illness. This diagnosis is not used in contemporary practice.
MSH

behavior exhibiting excessive or uncontrollable emotion, such as fear or panic; mental disorder characterized by emotional excitability and sometimes by amnesia or a physical deficit, such as paralysis, or a sensory deficit, without an organic cause.
CSP

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zubní korunky – technika post and core

Use of a metal casting, usually with a post in the pulp or root canal, designed to support and retain an artificial crown.
MSH

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dursban

An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
MSH

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dusík – sloučeniny

Inorganic compounds that contain nitrogen as an integral part of the molecule.
MSH

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virus katarální horečky ovcí

The type species of ORBIVIRUS causing a serious disease in sheep, especially lambs. It may also infect wild ruminants and other domestic animals.
MSH

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tepelná vodivost

The heat flow across a surface per unit area per unit time, divided by the negative of the rate of change of temperature with distance in a direction perpendicular to the surface. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
MSH

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imunoglobulin A sekreční

The principle immunoglobulin in exocrine secretions such as milk, respiratory and intestinal mucin, saliva and tears. The complete molecule (around 400 kD) is composed of two four-chain units of IMMUNOGLOBULIN A, one SECRETORY COMPONENT and one J chain (IMMUNOGLOBULIN J-CHAINS).
MSH

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chudé oblasti

City, urban, rural, or suburban areas which are characterized by severe economic deprivation and by accompanying physical and social decay.
MSH

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dystonia musculorum deformans

A condition characterized by focal DYSTONIA that progresses to involuntary spasmodic contractions of the muscles of the legs, trunk, arms, and face. The hands are often spared, however, sustained axial and limb contractions may lead to a state where the body is grossly contorted. Onset is usually in the first or second decade. Familial patterns of inheritance, primarily autosomal dominant with incomplete penetrance, have been identified. (Adams et al., Principles of Neurology, 6th ed, p1078)
MSH

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Nocardiaceae

A family of gram-positive, aerobic actinomycetes found in soil and animal tissue. Some species are the cause of infection in man and animals.
MSH

A taxonomic family of Gram positive, aerobic bacterium in the phylum Actinobacteria that includes the genera Nocardia, Rhodococcus and Smaragdicoccus, among others.
NCI

family of gram positive, aerobic actinomycetes found in soil and animal tissue; some species are the cause of infection in man and animals.
CSP

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nemoci kostí

Diseases of BONES.
MSH

condition in which there is a deviation from or interruption of the normal structure or function of the bones.
CSP

Your bones help you move, give you shape and support your body. They are living tissues that rebuild constantly throughout your life. During childhood and your teens, your body adds new bone faster than it removes old bone. After about age 20, you can lose bone faster than you make bone. To have strong bones when you are young, and to prevent bone loss when you are older, you need to get enough calcium, vitamin D and exercise.

There are many kinds of bone problems:

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases


MEDLINEPLUS

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