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amitriptylin

Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
MSH

tricyclic antidepressant with anticholinergic and sedative properties; it appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters; it also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
CSP

A derivative of dibenzocycloheptadiene and a tricyclic antidepressant. Amitriptyline inhibits the re-uptake of norepinephrine and serotonin by the presynaptic neuronal membrane in the central nervous system (CNS), thereby increasing the synaptic concentration of norepinephrine and serotonin. Due to constant stimulation to these receptors, amitriptyline may produce a downregulation of adrenergic and serotonin receptors, which may contribute to the antidepressant activity.
NCI

A drug that is used to treat depression and may be given to treat anxiety, sleep disorders, and pain. It is also being studied in an oral or gel form in the treatment of nerve pain caused by chemotherapy. Amitriptyline is a type of tricyclic antidepressant.
NCI

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hemodialyzační roztoky

Solutions prepared for hemodialysis. The composition of the pre-dialysis solution may be varied in order to determine the effect of solvated metabolites on anoxia, malnutrition, acid-base balance, etc. Of principal interest are the effect of the choice of buffers (e.g., acetate or carbonate), the addition of cations (Na+, K+, Ca2+), and addition of carbohydrates (glucose).
MSH

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napínací reflex

Reflex contraction of a muscle in response to stretching, which stimulates muscle proprioceptors.
MSH

reflex contraction of a muscle in response to passive longitudinal stretching.
CSP

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zubní materiály

Materials used in the production of dental bases, restorations, impressions, prostheses, etc.
MSH

broad term to cover material used in temporary or permanent dental implants, biomaterials, prosthetic devices, etc; index narrower term when possible.
CSP

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asialoglykoproteiny

Endogenous glycoproteins from which SIALIC ACID has been removed by the action of sialidases. They bind tightly to the ASIALOGLYCOPROTEIN RECEPTOR which is located on hepatocyte plasma membranes. After internalization by adsorptive ENDOCYTOSIS they are delivered to LYSOSOMES for degradation. Therefore receptor-mediated clearance of asialoglycoproteins is an important aspect of the turnover of plasma glycoproteins. They are elevated in serum of patients with HEPATIC CIRRHOSIS or HEPATITIS.
MSH

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monobaktamy

Monocyclic, bacterially produced or semisynthetic beta-lactam antibiotics. They lack the double ring construction of the traditional beta-lactam antibiotics and can be easily synthesized.
MSH

group of antibiotics containing beta lactam rings which are cleaved by the beta lactamases produced by almost all gram negative bacteria.
CSP

Compounds containing a four-membered ring with an amide nitrogen and a keto group. This configuration includes bacteriostatic, cell-wall inhibiting antibiotics, such as penicillins and cephalosporins, their analogs and derivatives, such as the penem (or penam) compounds, clavulanic acids, and monobactams. They are substrates for and may act as inhibitors of bacterial beta-lactamases. (MeSH)
NCI

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amputace – pahýly

The part of a limb or tail following amputation that is proximal to the amputated section.
MSH

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reaktivní hemofagocytární syndrom

Proliferation of HISTIOCYTES in response to viral, bacterial, fungal, or parasitic infections.
MSH

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posílení sociální

The strengthening of a response with a social reward such as a nod of approval, a parent`s love or attention.
MSH

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zuby – estetické fazety

The use of a layer of tooth-colored material, usually porcelain or acrylic resin, applied to the surface of natural teeth, crowns, or pontics by fusion, cementation, or mechanical retention.
MSH

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asociace

A functional relationship between psychological phenomena of such nature that the presence of one tends to evoke the other; also, the process by which such a relationship is established.
MSH

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morfogeneze

The development of anatomical structures to create the form of a single- or multi-cell organism. Morphogenesis provides form changes of a part, parts, or the whole organism.
MSH

The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. [GOC:go_curators, ISBN:0521436125]
GO

The process of shape formation: the processes that are responsible for producing the complex shapes of adults from the simple ball of cells that derives from division of the fertilized egg. (On-line Medical Dictionary)
NCI

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opioidní analgetika

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.
MSH

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hepatektomie

Excision of all or part of the liver. (Dorland, 28th ed)
MSH

excision of all or part of the liver.
CSP

Surgery to remove all or part of the liver.
NCI

Surgical removal of all or part of the liver.
NCI

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reoperace

A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.
MSH

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zubní náhrady – přesné přichycení

A precision device used for attaching a fixed or removable partial denture to the crown of an abutment tooth or a restoration. One type is the intracoronal attachment and the other type is the extracoronal attachment. It consists of a female portion within the coronal portion of the crown of an abutment and a fitted male portion attached to the denture proper. (Jablonski, Dictionary of Dentistry, 1992, p85; from Boucher`s Clinical Dental Terminology, 4th ed, p264)
MSH

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atractylosid

A glycoside of a kaurene type diterpene that is found in some plants including Atractylis gummifera (ATRACTYLIS); COFFEE; XANTHIUM, and CALLILEPIS. Toxicity is due to inhibition of ADENINE NUCLEOTIDE TRANSLOCASE.
MSH

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viry myšího sarkomu

group of 2 viruses, MSV(Harvey) and MSV(Moloney); MSV(M) causes a rhabdomysarcoma.
CSP

A group of replication-defective viruses, in the genus GAMMARETROVIRUS, which are capable of transforming cells, but which replicate and produce tumors only in the presence of Murine leukemia viruses (LEUKEMIA VIRUS, MURINE).
MSH

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Androgens, Synthetic

steroidal compounds related to testosterone.
CSP

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hepatorenální syndrom

Functional KIDNEY FAILURE in patients with liver disease, usually LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL), and in the absence of intrinsic renal disease or kidney abnormality. It is characterized by intense renal vasculature constriction, reduced renal blood flow, OLIGURIA, and sodium retention.
MSH

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ústavní terapie

A specialized residential treatment program for behavior disorders including substance abuse. It may include therapeutically planned group living and learning situations including teaching of adaptive skills to help patient functioning in the community. (From Kahn, A. P. and Fawcett, J. Encyclopedia of Mental Health, 1993, p320.)
MSH

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depersonalizace

State in which an individual perceives or experiences a sensation of unreality concerning the self or the environment; it is seen in disorders such as schizophrenia, affection disorders, organic mental disorders, and personality disorders. (APA, Thesaurus of Psychological Index Terms, 8th ed.)
MSH

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sluchová percepce – poruchy

Acquired or developmental cognitive disorders of AUDITORY PERCEPTION characterized by a reduced ability to perceive information contained in auditory stimuli despite intact auditory pathways. Affected individuals have difficulty with speech perception, sound localization, and comprehending the meaning of inflections of speech.
MSH

A disorder characterized by the inability of the brain to properly interpret or process the auditory signals it receives from the anatomic structures of the ear.
NCI

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Mucor

A genus of zygomycetous fungi of the family Mucoraceae, order Mucorales. It is primarily saprophytic, but may cause MUCORMYCOSIS in man from spores germinating in the lungs.
MSH

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herpes zoster ophthalmicus

Virus infection of the Gasserian ganglion and its nerve branches characterized by pain and vesicular eruptions with much swelling. Ocular involvement is usually heralded by a vesicle on the tip of the nose. This area is innervated by the nasociliary nerve.
MSH

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odpočinek

Freedom from activity.
MSH

freedom from physical activity.
CSP

Freedom from activity. (WordNet)
NCI

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drogy vyráběné ilegálně

Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.
MSH

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autofagie

segregation of part of the cell`s own cytoplasmic material within a membrane and its digestion after fusion of the segregated vacuole with a lysosome.
CSP

The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. [ISBN:0198547684, PMID:11099404, PMID:9412464]
GO

Autophagy is a biological process that involves the lysosomal degradation of intracellular components using it a cell`s own machinery. This process can play a role in cellular defense, embryonic development, and cell growth.
NCI

A normal process in which a cell destroys proteins and other substances in its cytoplasm (the fluid inside the cell membrane but outside the nucleus), which may lead to cell death. Autophagy may prevent normal cells from developing into cancer cells, but it may also protect cancer cells by destroying anticancer drugs or substances taken up by them.
NCI

The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.
MSH

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muscimol

A neurotoxic isoxazole isolated from species of AMANITA. It is obtained by decarboxylation of IBOTENIC ACID. Muscimol is a potent agonist of GABA-A RECEPTORS and is used mainly as an experimental tool in animal and tissue studies.
MSH

3-hydroxy-5-aminomethylisoxazole; high affinity GABA-A (chloride channel) agonist used as a GABAmimetic drug and autoradiographic label.
CSP

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Hexokinase 2

Expressed in human heart, skeletal muscle, and adipose tissue and encoded by insulin-responsive HK2 Gene (Hexokinase Family), outer mitochondrial membrane-bound 917-amino acid 102-kD monomeric Hexokinase 2 promotes glycolysis. HK2 contains glucose- and ATP-binding sites and a hexokinase domain. The C-terminus contains catalytic activity; membrane binding and regulation associate with the N-terminus. Allosterically regulated by product, HK2 converts aldo-/keto-hexoses to hexose-6-phosphate, the first step of many metabolic pathways. (from LocusLink, Swiss-Prot, OMIM, and NCI)
NCI

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