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česneky

Herbaceous biennial plants and their edible bulbs, belonging to the Liliaceae.
MSH

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dextrorfan

Dextro form of levorphanol. It acts as a noncompetitive NMDA receptor antagonist, among other effects, and has been proposed as a neuroprotective agent. It is also a metabolite of DEXTROMETHORPHAN.
MSH

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uspokojení

Full gratification of a need or desire followed by a state of relative insensitivity to that particular need or desire.
MSH

the state or condition reached after totally satisfying a desire or need; e.g., abolition of the desire to eat after full gratification of appetite.
CSP

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azaserin

Antibiotic substance produced by various Streptomyces species. It is an inhibitor of enzymatic activities that involve glutamine and is used as an antineoplastic and immunosuppressive agent.
MSH

a kind of antibiotic and antitumor drug
CHV

A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39156&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39156&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C289″ NCI Thesaurus)
PDQ

A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. (NCI04)
NCI

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infertilita mužská

The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.
MSH

Infertility is a term doctors use if a man hasn`t been able to get a woman pregnant after at least one year of trying. Male infertility can result from physical problems, hormone problems, and lifestyle or environmental factors.

About a third of the time, infertility is because of a problem with the man. One third of the time, it is a problem with the woman. Sometimes no cause can be found.

If you suspect you are infertile, see your doctor. There are tests that may tell if you have fertility problems. When it is possible to find the cause, treatments may include medicines, surgery, or assisted reproductive technologies. Happily, two-thirds of couples treated for infertility are able to have babies.

National Women`s Health Information Center


MEDLINEPLUS

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vačice

New World marsupials of the family Didelphidae. Opossums are omnivorous, largely nocturnal and arboreal MAMMALS, grow to about three feet in length, including the scaly prehensile tail, and have an abdominal pouch in which the young are carried at birth.
MSH

small to medium sized omnivorous marsupials; marsupium is rudimentary or well developed; tail is prehensile and naked for at least part of its length; crepuscular and nocturnal; may be terrestrial, aboreal, or semiaquatic.
CSP

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diagnostické techniky urologické

detection or classification of urinary tract diseases or disorders.
CSP

Methods and procedures for the diagnosis of diseases or dysfunction of the urinary tract or its organs or demonstration of its physiological processes.
MSH

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schizofrenie paranoidní

A chronic form of schizophrenia characterized primarily by the presence of persecutory or grandiose delusions, often associated with hallucination.
MSH

psychotic behavior accompanied simultaneously by persecutory or grandiose delusions (paranoia) and hallucinations (schizophrenia); delusional jealousy may be present.
CSP

A subtype of schizophrenia characterized by prominent delusions (typically persecutory or grandiose) or hallucinations in the context of a relative preservation of cognitive functioning and affect.
NCI

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Bacillus anthracis

causes anthrax in humans and animals.
CSP

A species of bacteria that causes ANTHRAX in humans and animals.
MSH

Any bacterial organism that can be assigned to the species Bacillus anthracis.
NCI

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injekce intralymfatické

Injections into the lymph nodes or the lymphatic system.
MSH

Injection, intralymphatic


HL7V3.0

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metaproterenol

A beta-2 adrenergic agonist used in the treatment of ASTHMA and BRONCHIAL SPASM.
MSH

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diazoxid

A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
MSH

peripheral vasodilator that reduces blood pressure; diazoxide also has antidiuretic and hypoglycemic effects.
CSP

A benzothiadiazine derivate with antihypertensive and hyperglycemic activities. Diazoxide increases membrane permeability to potassium ions in vascular smooth muscle, thereby stabilizing the membrane action potential and preventing vascular smooth muscle contraction; this results in peripheral vasodilatation and decreases in peripheral vascular resistance. This agent also inhibits insulin release by interacting with ATP-sensitive potassium channels of pancreatic islet beta-cells. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39290&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39290&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C428″ NCI Thesaurus)
PDQ

A benzothiadiazine derivate with antihypertensive and hyperglycemic activities. Diazoxide increases membrane permeability to potassium ions in vascular smooth muscle, thereby stabilizing the membrane action potential and preventing vascular smooth muscle contraction; this results in peripheral vasodilatation and decreases in peripheral vascular resistance. This agent also inhibits insulin release by interacting with ATP-sensitive potassium channels of pancreatic islet beta-cells.
NCI

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skléra

The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)
MSH

tough white outer coat of the eyeball, continuous anteriorly with the cornea and posteriorly with the external sheath of the optic nerve.
CSP

The white layer of the eye that covers most of the outside of the eyeball.
NCI

The white, opaque, fibrous, outer tunic of the eyeball, covering it entirely excepting the segment covered anteriorly by the cornea. It is essentially avascular but contains apertures for vessels, lymphatics, and nerves. It receives the tendons of insertion of the extraocular muscles and at the corneoscleral junction contains the canal of Schlemm. (From Cline et al., Dictionary of Visual Science, 4th ed)
NCI

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bakteriurie

The presence of bacteria in the urine which is normally bacteria-free. These bacteria are from the URINARY TRACT and are not contaminants of the surrounding tissues. Bacteriuria can be symptomatic or asymptomatic. Significant bacteriuria is an indicator of urinary tract infection.
MSH

presence of bacteria in the urine with or without consequent urinary tract infection.
CSP

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insekticidy – rezistence

The development by insects of resistance to insecticides.
MSH

development by insects of resistance to insecticides.
CSP

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porucha orgasmu

A change in the ability to obtain orgasm or in the quality of the orgasmic sensation.
NCI

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dideoxyadenosin

A dideoxynucleoside compound in which the 3`-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is an inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal side effect is nephrotoxicity. In vivo, dideoxyadenosine is rapidly metabolized to DIDANOSINE (ddI) by enzymatic deamination; ddI is then converted to dideoxyinosine monophosphate and ultimately to dideoxyadenosine triphosphate, the putative active metabolite.
MSH

A synthetic nucleoside analogue of deoxyadenosine and a prodrug of didanosine in which the 3` hydroxyl group on the ribose moiety is replaced by a hydrogen atom. Dideoxyadenosine competitively inhibits adenylyl cyclase, thereby reducing levels of cyclic adenosine monophosphate (cAMP). By inhibiting cAMP-mediated gene activation in tumor cells, this agent may retard tumor cell proliferation. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40799&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40799&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C429″ NCI Thesaurus)
PDQ

A synthetic nucleoside analogue of deoxyadenosine and a prodrug of didanosine in which the 3` hydroxyl group on the ribose moiety is replaced by a hydrogen atom. Dideoxyadenosine competitively inhibits adenylyl cyclase, thereby reducing levels of cyclic adenosine monophosphate (cAMP). By inhibiting cAMP-mediated gene activation in tumor cells, this agent may retard tumor cell proliferation. (NCI04)
NCI

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syndrom histiocytů barvy mořské modři

A congenital disease caused by an inborn error involving APOLIPOPROTEINS E leading to abnormal LIPID METABOLISM and the accumulation of GLYCOSPHINGOLIPIDS, particularly SPHINGOMYELINS in the HISTIOCYTES. This disorder is characterized by SPLENOMEGALY and the sea-blue histiocytes in the spleen and bone marrow after May Grunwald staining.
MSH

A rare, inherited or acquired syndrome characterized by the presence of histiocytes in the bone marrow which contain granules stained blue with hematoxylin-eosin stain, mild thrombocytopenia and purpura, and splenomegaly.
NCI

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Barrettův jícen

A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett`s columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.
MSH

A condition in which the cells lining the lower part of the esophagus have changed or been replaced with abnormal cells that could lead to cancer of the esophagus. The backing up of stomach contents (reflux) may irritate the esophagus and, over time, cause Barrett`s esophagus.
NCI

Esophageal lesion lined with columnar metaplastic epithelium which is flat or villiform. Barrett epithelium is characterized by two different types of cells: goblet cells and columnar cells. The symptomatology of Barrett esophagus is that of gastro-esophageal reflux. It is the precursor of most esophageal adenocarcinomas. (WHO)
NCI

syndrome including peptic ulcer of the lower esophagus, often with stricture, due to the presence of columnar lined epithelium, which may contain functional mucous cells, parietal cells, or chief cells in the esophagus instead of normal squamous cell epithelium; sometimes pre-malignant, followed by esophageal adenocarcinoma.
CSP

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insulinu podobný růstový faktor I

A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
MSH

Elevated serum levels of insulin-like growth factor-1 (IGF-1) may identify premenopausal women who are likely to develop breast cancer before age 50. (from Int J Cancer 2000;88:828-832 via Medscape)
NCI

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ortopedie

A surgical specialty which utilizes medical, surgical, and physical methods to treat and correct deformities, diseases, and injuries to the skeletal system, its articulations, and associated structures.
MSH

branch of surgery that is especially concerned with the preservation and restoration of the functions of the skeletal system, its articulations and associated structures.
CSP

profession
CHV

The branch of surgery broadly concerned with the skeletal system (bones and joints). (from On-line Medical Dictionary)
NCI

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enzymy – represe

The interference in synthesis of an enzyme due to the elevated level of an effector substance, usually a metabolite, whose presence would cause depression of the gene responsible for enzyme synthesis.
MSH

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diethylnitrosamin

A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
MSH

nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties.
CSP

A synthetic light-sensitive, volatile, clear yellow oil that is soluble in water, lipids, and other organic solvents. It is used as gasoline and lubricant additive, antioxidant, and stabilizer for industry materials. When heated to decomposition, N-nitrosodiethylamine emits toxic fumes of nitrogen oxides. N-Nitrosodiethylamine affects DNA integrity, probably by alkylation, and is used in experimental research to induce liver tumorigenesis. It is considered to be reasonably anticipated to be a human carcinogen. (NCI05)
NCI

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péče o sebe

Performance of activities or tasks traditionally performed by professional health care providers. The concept includes care of oneself or one`s family and friends.
MSH

consumer (patients or their families or friends) performance of medical activities traditionally performed by professional health care providers; for daily self maintenance (dressing, hygiene, eating, etc.), use FUNCTIONAL ABILITY.
CSP

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zobák

In some animals, the jaws together with their horny covering. The beak usually refers to the bill of birds in which the whole varies greatly in form according of the food and habits of the bird. While the beak refers most commonly to birds, the anatomical counterpart is found also in the turtle, squid, and octopus. (From Webster, 3d ed & Storer, et al., General Zoology, 6th ed, p491, 755)
MSH

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intenzivní péče o novorozence

Continuous care and monitoring of newborn infants with life-threatening conditions, in any setting.
MSH

continuous care and monitoring of newborn infants with life-threatening conditions, usually administered in specially equipped units of a health care facility.
CSP

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osteogeneze

The process of bone formation. Histogenesis of bone including ossification.
MSH

production of bone; histogenesis of bone including ossification; do not confuse with the growth and development of bone, BONE DEVELOPMENT.
CSP

The formation of bone or of a bony substance; the conversion of fibrous tissue or of cartilage into bone or a bony substance.
NCI

The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. [GOC:mtg_mpo, PMID:17572649]
GO

The formation of bone or of a bony substance; the conversion of fibrous tissue or of cartilage into bone or a bony substance.
NCI

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epidurální nádory

Neoplasms located in the space between the vertebral PERIOSTEUM and DURA MATER surrounding the SPINAL CORD. Tumors in this location are most often metastatic in origin and may cause neurologic deficits by mass effect on the spinal cord or nerve roots or by interfering with blood supply to the spinal cord.
MSH

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dihydroergokryptin

A 9,10alpha-dihydro derivative of ERGOTAMINE that contains an isopropyl sidechain at the 2` position and an alpha-isobutyl sidechain at 5`alpha position of the molecule.
MSH

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poruchy senzitivity

Disorders of the special senses (i.e., VISION; HEARING; TASTE; and SMELL) or somatosensory system (i.e., afferent components of the PERIPHERAL NERVOUS SYSTEM).
MSH

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