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nehty

The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.
MSH

The cutaneous plate on the dorsal surface of the distal end of a finger or toe. (NCI)
NCI

The cutaneous plate on the dorsal surface of the distal end of a finger or toe.
NCI

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Phaeophyta

A division of predominantly marine EUKARYOTA, commonly known as brown algae, having CHROMATOPHORES containing carotenoid PIGMENTS, BIOLOGICAL. ALGINATES and phlorotannins occur widely in all major orders. They are considered the most highly evolved algae because of their well-developed multicellular organization and structural complexity.
MSH

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klathrin

The main structural coat protein of COATED VESICLES which play a key role in the intracellular transport between membranous organelles. Each molecule of clathrin consists of three light chains (CLATHRIN LIGHT CHAINS) and three heavy chains (CLATHRIN HEAVY CHAINS) that form a structure called a triskelion. Clathrin also interacts with cytoskeletal proteins.
MSH

3-armed structural protein which forms cagelike lattices around the cytoplasmic face of intracellular vesicular membranes, where it regulates fusion and transport events.
CSP

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hormony ektopické

Hormones released from neoplasms or from other cells that are not the usual sources of hormones.
MSH

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radiodermatitida

A cutaneous inflammatory reaction occurring as a result of exposure to ionizing radiation.
MSH

A cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation.
NCI

A finding of cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation.
NCI

A skin condition that is a common side effect of radiation therapy. The affected skin becomes painful, red, itchy, and blistered.
NCI

A cutaneous inflammatory reaction occurring as a result of exposure to biologically effective levels of ionizing radiation.
NCI

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narkotika – antagonisté

Agents inhibiting the effect of narcotics on the central nervous system.
MSH

class of drugs used to treat opiate drug addiction.
CSP

Any agent that binds to or interferes with binding to any of the opioid receptor subtypes, thereby blocking the actions of opioid agonists.
NCI

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Allium

A genus of the plant family Liliaceae (sometimes classified as Alliaceae) in the order Liliales. Many produce pungent, often bacteriostatic and physiologically active compounds and are used as food, condiment, and medicament, the latter in traditional medicine.
MSH

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klofenapát

An oral hypolipemic agent primarily used in DOGS and RATS.
MSH

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nemocnice pro rekonvalescenty

Hospitals which provide care to the patient for the period following an acute illness until health is restored.
MSH

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radioterapie počítačová

Computer systems or programs used in accurate computations for providing radiation dosage treatment to patients.
MSH

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přirozený jazyk – zpracování

Computer processing of a language with rules that reflect and describe current usage rather than prescribed usage.
MSH

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alfa-krystaliny

A subclass of crystallins that provides the majority of refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Alpha-crystallins also act as molecular chaperones that bind to denatured proteins, keep them in solution and thereby maintain the translucency of the lens. The proteins exist as large oligomers that are formed from ALPHA-CRYSTALLIN A CHAIN and ALPHA-CRYSTALLIN B CHAIN subunits.
MSH

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klozapin

A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent.
MSH

tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent; binds several types of central nervous system receptors, and displays a unique pharmacological profile; it is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype, and also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity; agranulocytosis is a major adverse effect associated with administration of this agent.
CSP

a drug used to treat schizophrenia
CHV

A synthetic dibenzo-diazepine derivative, atypical antipsychotic Clozapine blocks several neurotransmitter receptors in the brain (dopamine type 4, serotonin type 2, norepinephrine, acetylcholine, and histamine receptors). Unlike traditional antipsychotic agents, it weakly blocks dopamine type 2 receptors. It relieves schizophrenic symptoms (hallucinations, delusions, dementia). (NCI04)
NCI

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domácnosti

domestic unit consisting of persons who live together; also includes the living spaces and possessions belonging to such a unit.
CSP

The group of persons who occupy a single housing unit.


HL7V3.0

A social unit comprised of one or more individuals living together (all of whom need not be related) in the same dwelling, who aggregate and share their incomes.
NCI

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potkani Gunn

Mutant strain of Rattus norvegicus which is used as a disease model of kernicterus.
MSH

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Neisseria gonorrhoeae

species of gram negative, aerobic bacteria primarily found in purulent venereal discharges; it is the causative agent of gonorrhea.
CSP

A species of gram-negative, aerobic bacteria primarily found in purulent venereal discharges. It is the causative agent of GONORRHEA.
MSH

Any bacterial organism that can be assigned to the species Neisseria gonorrhoeae.
NCI

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alveolitida alergická

A common interstitial lung disease caused by hypersensitivity reactions of PULMONARY ALVEOLI after inhalation of and sensitization to environmental antigens of microbial, animal, or chemical sources. The disease is characterized by lymphocytic alveolitis and granulomatous pneumonitis.
MSH

conditions in which inhalation of organic dusts results in hypersensitivity reactions at the alveolar level, associated with the production of precipitins.
CSP

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Cockayneův syndrom

A syndrome characterized by multiple system abnormalities including DWARFISM; PHOTOSENSITIVITY DISORDERS; PREMATURE AGING; and HEARING LOSS. It is caused by mutations of a number of autosomal recessive genes encoding proteins that involve transcriptional-coupled DNA REPAIR processes. Cockayne syndrome is classified by the severity and age of onset. Type I (classical; CSA) is early childhood onset in the second year of life; type II (congenital; CSB) is early onset at birth with severe symptoms; type III (xeroderma pigmentosum; XP) is late childhood onset with mild symptoms.
MSH

A genetic condition characterized by short stature, premature aging, sensitivity to light, and possibly deafness and mental retardation.
NCI

An autosomal recessive syndrome caused by mutations in the ERCC8 and ERCC6 genes. It is characterized by growth and developmental delay, vision and hearing impairment, and impairment of the peripheral nervous system function.
NCI

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kyselina hyaluronová

A natural high-viscosity mucopolysaccharide with alternating beta (1-3) glucuronide and beta (1-4) glucosaminidic bonds. It is found in the UMBILICAL CORD, in VITREOUS BODY and in SYNOVIAL FLUID. A high urinary level is found in PROGERIA.
MSH

A glucosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units that is a component of connective tissue, skin, vitreous humour, umbilical cord, synovial fluid and the capsule of certain microorganisms contributing to adhesion, elasticity, and viscosity of extracellular substances.
NCI

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alfa-adrenergní receptory

alpha-1 is coupled to phospholipase C, such that stimulation results in production of second messengers DAG and in inositol phosphates; alpha-2 is coupled to adenylate cyclase such that stimulation lowers cyclic AMP.
CSP

One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.
MSH

Expressed by Alpha Adrenergic Receptor Genes in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Alpha Adrenergic Receptors are one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Alpha-adrenergic receptors respond to blocking agents such as phenoxybenzamine and phentolamine. When coupled to adenylate cyclase through Gi protein, Alpha Adrenergic Receptor stimulation results in decreased intracellular cyclic AMP.
NCI

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nádory embryonální a germinální

Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. The concept does not refer to neoplasms located in the gonads or present in an embryo or FETUS.
MSH

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Americká nemocniční asociace

A professional society in the United States whose membership is composed of hospitals.
MSH

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Colchicum

A genus of poisonous, liliaceous plants. The roots (corms) of Colchicum autumnale, the fall crocus or meadow saffron, yield COLCHICINE, which is used as a biochemical tool and to treat gout. Other members of this genus yield saffron dye, flavoring agents, and aromatics.
MSH

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kyselina kyanovodíková

Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
MSH

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receptory imunologické

Cell surface molecules on cells of the immune system that specifically bind surface molecules or messenger molecules and trigger changes in the behavior of cells. Although these receptors were first identified in the immune system, many have important functions elsewhere.
MSH

cell surface molecules on cells of the immune system that specifically bind surface molecules or messenger molecules and trigger changes in the behavior of cells; although these receptors were first identified in the immune system, many have important functions elsewhere; not all immunologic receptors are tree`d under this term.
CSP

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nefrotický syndrom

A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
MSH

Nephrotic Syndrome: twenty-four hour urine protein > three grams. May be associated with hypoalbuminemia and hypercholesterolemia.
AIR

diseases involving defective kidney glomeruli, characterized by massive proteinuria and lipiduria with varying degrees of edema, hypoalbuminemia, and hyperlipidemia.
CSP

a kidney disease characterized by a high protein level in urine
CHV

A collection of symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction.
NCI

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aminoalkoholy

compounds possessing both a hydroxyl (-OH) and an amino group (-NH2).
CSP

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kolodion

A nitrocellulose solution in ether and alcohol. Collodion has a wide range of uses in industry including applications in the manufacture of photographic film, in fibers, in lacquers, and in engraving and lithography. In medicine it is used as a drug solvent and a wound sealant.
MSH

A general purpose reagent is a chemical reagent that has general laboratory application, that is used to collect, prepare, and examine specimens from the human body for diagnostic histopathology, cytology, and hematology, and that is not labeled or otherwise intended for a specific diagnostic application. General purpose reagents include cytological preservatives, decalcifying reagents, fixatives and adhesives, tissue processing reagents, isotonic solutions, and pH buffers.
SPN

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hydroxykortikosteroidy

A group of corticosteroids carrying hydroxy groups, usually in the 11- or 17-positions. They comprise the bulk of the corticosteroids used systemically. As they are relatively insoluble in water, salts of various esterified forms are often used for injections or solutions.
MSH

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rekreace

Activity engaged in for pleasure.
MSH

activity engaged in for pleasure, diversion, amusement or stimulation.
CSP

Any activity that is intended for refreshment or diversion.
NCI

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