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Sexuální masochismus

A disorder characterized by recurrent sexual urges, fantasies, or behaviors involving the act (real, not simulated) of being humiliated, beaten, bound, or otherwise made to suffer.
NCI

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Hypocreales

An order of fungi in the phylum ASCOMYCOTA that includes a number of species which are parasitic on higher plants, insects, or fungi. Other species are saprotrophic.
MSH

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oxytocin

A nonapeptide hormone released from the neurohypophysis (PITUITARY GLAND, POSTERIOR). It differs from VASOPRESSIN by two amino acids at residues 3 and 8. Oxytocin acts on SMOOTH MUSCLE CELLS, such as causing UTERINE CONTRACTIONS and MILK EJECTION.
MSH

peptide hormone produced by the posterior lobe of the pituitary gland that induces contraction of the smooth muscle of the uterus and the myoepithelial cells of the mammary gland.
CSP

Oxytocin (125 aa, ~13kDa) is encoded by the human OXT gene. This protein plays a role in smooth muscle contraction in both the mammary gland and uterus. Oxytocin also is involved in maternal-newborn bonding, cognition and many other psychological and physiological processes.
NCI

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chylus

An opaque, milky-white fluid consisting mainly of emulsified fats that passes through the lacteals of the small intestines into the lymphatic system.
MSH

Lymph mixed with fats absorbed by the small intestine.
FMA

A milky-white fluid that forms in the small intestine during digestion. It is made of lymph fluid and fats. Special lymph vessels carry chyle from the intestines to the blood.
NCI

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kyseliny nikotinové

2-, 3-, or 4-Pyridinecarboxylic acids. Pyridine derivatives substituted with a carboxy group at the 2-, 3-, or 4-position. The 3-carboxy derivative (NIACIN) is active as a vitamin.
MSH

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Shopeho virus papilomatózy králíků

infects cotton-tail rabbits, Sylvilagus floridanus, naturally; domestic rabbits can be infected by scarification; skin warts, which may become malignant, are produced.
CSP

The type species of KAPPAPAPILLOMAVIRUS. It is reported to occur naturally in cottontail rabbits in North America.
MSH

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hypotalamus

ventral part of the diencephalon extending from the region of the optic chiasm to the caudal border of the mammillary bodies and forming the inferior and lateral walls of the third ventricle.
CSP

The area of the brain that controls body temperature, hunger, and thirst.
NCI

An important supervisory center in the brain, rich in ganglia, nerve fibers, and synaptic connections. It is composed of several sections called nuclei, each of which controls a specific function. The hypothalamus regulates body temperature, blood pressure, heartbeat, metabolism of fats and carbohydrates, and sugar levels in the blood. Through direct attachment to the pituitary gland, the hypothalamus also meters secretions controlling water balance and milk production in the female. The role of the hypothalamus in awareness of pleasure and pain is well established in the laboratory. It is involved in the expression of emotions, such as fear and rage, and in sexual behaviors. Despite its numerous vital functions, the hypothalamus in humans accounts for only 1/300 of total brain weight, and is about the size of an almond. Structurally, it is joined to the thalamus; the two work together to monitor the sleep-wake cycle.
NCI

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párová vazba

In animals, the social relationship established between a male and female for reproduction. It may include raising of young.
MSH

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Structure of cisterna chyli

An enlarged sac-like lymph vessel located in the lumbar region of the abdominal cavity, just right of the ABDOMINAL AORTA.
MSH

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nitrendipin

A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
MSH

1,4-dihydro-2,6-dimethyl-4- nitrophenyl-3,5-pyridine carboxyic acid ethylmethyl ester; calcium channel blocker of the nifedipine family.
CSP

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Signal Peptides

N-terminal, hydrophobic sequences which mediate the attachment of newly translated polypeptide chains to intracellular membranes; in some membrane proteins the signal peptide remains as a permanent anchor, while in secretory proteins it is cleaved.
CSP

The N-terminal sequence of a secreted protein that interacts with a signal recognition particle and is required for transport through the cell membrane.
NCI

Highly hydrophobic amino acid sequences of proteins that must cross through membranes to arrive at their functioning cellular location (such as secreted and membrane proteins). They are 15 to 60 amino acids long and reside at the amino-terminus (leader signal peptides) or internally. By binding to signal recognition particles, these sequences direct nascent protein-ribosome complexes to a membrane where the protein is inserted during translation. Signal peptides direct translational uptake of the protein by various membranes -endoplamic reticulum, mitochondrial, chloroplast, peroxisomal, etc. Leader signal sequences on non-membrane proteins are ultimately removed by specific peptidases.
MSH

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Icelandic language

An Indo-European language belonging to the North Germanic (Scandinavian) branch; the official language of Iceland.
NCI

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beta-buňky

A cell that composes the bulk of the islets of Langerhans and secretes insulin.
NCI

A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.
MSH

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klenbuterol

A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
MSH

A substituted phenylaminoethanol and a long-acting beta-2 adrenergic agonist with sympathomimetic activity. Clenbuterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3`,5`-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of smooth muscle. In addition, clenbuterol also stimulates central nervous system (CNS), and causes an increase in blood pressure and heart rate due to both beta-2 and beta-1 adrenergic activities. This agent may also exert an anabolic or anti-catabolic effect due to as of yet unidentified mechanisms.
NCI

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nitrosaminy

A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties.
MSH

any of a group of N-nitroso derivatives of secondary amines formed by the combining of nitrates with amines; some show carcinogenic activity.
CSP

Any of a class of organic compounds with the general formula R2NNO or RNHNO, present in various foods and other products and found to be carcinogenic in laboratory animals. (dictionary.com)
NCI

A type of chemical found in tobacco products and tobacco smoke. Nitrosamines are also found in many foods, including fish, beer, fried foods, and meats. Some nitrosamines cause cancer in laboratory animals and may increase the risk of certain types of cancer in humans.
NCI

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virus Sindbis

The type species of ALPHAVIRUS normally transmitted to birds by CULEX mosquitoes in Egypt, South Africa, India, Malaya, the Philippines, and Australia. It may be associated with fever in humans. Serotypes (differing by less than 17% in nucleotide sequence) include Babanki, Kyzylagach, and Ockelbo viruses.
MSH

transmitted by mosquitoes (Culex); causes Sindbis fever in southern and eastern Africa, Egypt, Israel, India, Phillipines, and eastern Australia.
CSP

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nelegitimnost

The state of birth outside of wedlock. It may refer to the offspring or the parents.
MSH

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papaverin

An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
MSH

opium alkaloid used as a smooth muscle relaxant and weak analgesic.
CSP

An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39545&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39545&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C726″ NCI Thesaurus)
PDQ

An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. As a direct-acting smooth muscle relaxant, papaverine is not closely related to the other opium alkaloids in structure or pharmacological actions; its mechanism of action may involve the non-selective inhibition of phosphodiesterases and direct inhibition of calcium channels. This agent also exhibits antiviral activity against respiratory syncytial virus, cytomegalovirus, and HIV. (NCI04)
NCI

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klonorchiáza

Infection of the biliary passages with CLONORCHIS SINENSIS, also called Opisthorchis sinensis. It may lead to inflammation of the biliary tract, proliferation of biliary epithelium, progressive portal fibrosis, and sometimes bile duct carcinoma. Extension to the liver may lead to fatty changes and cirrhosis. (From Dorland, 27th ed)
MSH

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nesupresibilní insulinu podobná aktivita

A blood protein (NSILA) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of Cohn fraction III, 10% of the activity is found in the supernatant (NSILA-S) and the remaining activity in the precipitate (NSILA-P). The latter is a large molecular compound, much less stable than the soluble fraction. NSILA-S is a more potent growth factor than insulin and exhibits sulfation activity.
MSH

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kůže – nemoci infekční

Skin diseases caused by bacteria, fungi, parasites, or viruses.
MSH

skin diseases caused by bacteria, fungi, parasites, or viruses; may present on the surface of the skin, or underlying dermal layers.
CSP

A disorder characterized by an infectious process involving the skin.
NCI

Your skin helps protect you from germs, but sometimes it can get infected by them. Some common types of skin infections are

Your skin can also get parasites, such as head lice and scabies.

Treatment of skin infections depends on the cause.


MEDLINEPLUS

An inflammatory process affecting the skin, caused by bacteria, viruses, parasites, or fungi. Examples of bacterial infection include carbuncles, furuncles, impetigo, erysipelas, and abscesses. Examples of viral infection include shingles, warts, molluscum contagiosum, and pityriasis rosea. Examples of parasitic infection include scabies and lice. Examples of fungal infection include athlete`s foot, yeast infection, and ringworm.
NCI

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imunita přirozená

The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS.
MSH

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paraldehyd

A hypnotic and sedative with anticonvulsant effects. However, because of the hazards associated with its administration, its tendency to react with plastic, and the risks associated with its deterioration, it has largely been superseded by other agents. It is still occasionally used to control status epilepticus resistant to conventional treatment. (From Martindale, The Extra Pharmacopoeia, 30th ed, p608-9)
MSH

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kobalt – radioisotopy

Unstable isotopes of cobalt that decay or disintegrate emitting radiation. Co atoms with atomic weights of 54-64, except 59, are radioactive cobalt isotopes.
MSH

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virus varioly

A species of ORTHOPOXVIRUS causing infections in humans. No infections have been reported since 1977 and the virus is now believed to be virtually extinct.
MSH

species of orthopoxvirus causing infections in humans, virtually extinct in nature.
CSP

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imunoglobuliny – J-řetězce

A 15 kD “joining” peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light and heavy chains.
MSH

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parazitologie

The study of the structure, growth, function, genetics, and reproduction of parasites, and PARASITIC DISEASES.
MSH

A branch of biology which deals with parasitic organisms with a strong emphasis on their role in disease.
NCI

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kuandu

Prehensile-tailed PORCUPINES, in the family Erethizontidae.
MSH

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sociální facilitace

any enhancement of a motivated behavior in which individuals do the same thing with some degree of mutual stimulation and consequent coordination.
CSP

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imprinting (psychologie)

A particular kind of learning characterized by occurrence in very early life, rapidity of acquisition, and relative insusceptibility to forgetting or extinction. Imprinted behavior includes most (or all) behavior commonly called instinctive, but imprinting is used purely descriptively.
MSH

Rapid learning process that takes place during early critical periods of development
CHV

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