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faktor XII

Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease. Mutations in the gene for factor XII that appear to increase factor XII amidolytic activity are associated with HEREDITARY ANGIOEDEMA TYPE III.
MSH

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alfa-krystaliny – řetězec A

One of the subunits of alpha-crystallins. Unlike ALPHA-CRYSTALLIN B CHAIN the expression of ALPHA-CRYSTALLIN A CHAIN is limited primarily to the lens (LENS, CRYSTALLINE).
MSH

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Brassica rapa

A plant species cultivated for the seed used as animal feed and as a source of canola cooking oil.
MSH

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labetalol

A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
MSH

A third generation selective alpha-1-adrenergic antagonist and non-selective beta-adrenergic antagonist with vasodilatory and antihypertensive properties. Labetalol competitively binds to alpha-1-adrenergic receptors in vascular smooth muscle, thereby inhibiting the adrenergic stimulation of endothelial cell function and vasoconstriction in peripheral blood vessels. This agent also binds to beta-receptors in the bronchial and vascular smooth muscle, resulting in a decrease in adrenergic stimulation. The result is a decrease in resting and exercise heart rates, cardiac output, and in both systolic and diastolic blood pressure, thereby resulting in vasodilation, and negative chronotropic and inotropic cardiac effects.
NCI

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chromogenní sloučeniny

Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).
MSH

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Dálný východ

A geographic area of east and southeast Asia encompassing CHINA; HONG KONG; JAPAN; KOREA; MACAO; MONGOLIA; and TAIWAN.
MSH

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elementy Alu

The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
MSH

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reagenční soupravy diagnostické

Commercially prepared reagent sets, with accessory devices, containing all of the major components and literature necessary to perform one or more designated diagnostic tests or procedures. They may be for laboratory or personal use.
MSH

3C; Product Evaluation, Research, and Monitoring; Diagnostic Reagents and Test Kits (FMB)
NCI

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laktace

The processes of milk secretion by the maternal MAMMARY GLANDS after PARTURITION. The proliferation of the mammary glandular tissue, milk synthesis, and milk expulsion or let down are regulated by the interactions of several hormones including ESTRADIOL; PROGESTERONE; PROLACTIN; and OXYTOCIN.
MSH

production and secretion of milk by the mammary glands.
CSP

The secretion of milk by the mammary gland. [ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

production and secretion of milk from milk producing cell
CHV

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chromozómy lidské, pár 19

A specific pair of GROUP F CHROMOSOMES of the human chromosome classification.
MSH

The designation for each member of the nineteenth largest human autosomal chromosome pair. Chromosome 19 spans more than 63 million base pairs and represents between 2 and 2.5% of the total DNA in normal diploid cells.
NCI

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alkoholy mastné

Usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4 carbons, derived from natural fats and oils, including lauryl, stearyl, oleyl, and linoleyl alcohols. They are used in pharmaceuticals, cosmetics, detergents, plastics, and lube oils and in textile manufacture. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
MSH

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amébicidy

Agents which are destructive to amebae, especially the parasitic species causing AMEBIASIS in man and animal.
MSH

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receptory FSH

Cell surface proteins that bind FOLLICLE STIMULATING HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells.
MSH

Follicle-stimulating hormone receptor (695 aa, ~78 kDa) is encoded by the human FSHR gene. This protein is involved in the modulation of hormone binding and signaling and the mediation of both gonad development and gamete differentiation.
NCI

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jazykové poruchy

Conditions characterized by deficiencies of comprehension or expression of written and spoken forms of language. These include acquired and developmental disorders.
MSH

conditions characterized by deficiencies of comprehension or expression of written and spoken forms of language; includes acquired and developmental disorders.
CSP

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cilastatin

A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
MSH

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nervus femoralis

A nerve originating in the lumbar spinal cord (usually L2 to L4) and traveling through the lumbar plexus to provide motor innervation to extensors of the thigh and sensory innervation to parts of the thigh, lower leg, and foot, and to the hip and knee joints.
MSH

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oxidoreduktasy aminokyselin

A class of enzymes that catalyze oxidation-reduction reactions of amino acids.
MSH

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receptory transferinu

Membrane glycoproteins found in high concentrations on iron-utilizing cells. They specifically bind iron-bearing transferrin, are endocytosed with its ligand and then returned to the cell surface where transferrin without its iron is released.
MSH

major vehicle for cellular uptake of iron; receptor expression is tightly regulated by available iron, via an “iron-responsive element” (IRE) on its mRNA which prevents translation when occupied by an iron- sensitive binding protein.
CSP

Homodimeric human Transferrin Receptors (M28B Peptidase Family) are type II membrane proteins involved in the cellular import of transferrin-bound iron and appear necessary for iron metabolism, cell function, and erythrocyte differentiation. (NCI)
NCI

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virus Lassa

etiologic agent of Lassa fever; common infective agent in humans in West Africa.
CSP

A species of ARENAVIRUS, part of the Old World Arenaviruses (ARENAVIRUSES, OLD WORLD), and the etiologic agent of LASSA FEVER. LASSA VIRUS is a common infective agent in humans in West Africa. Its natural host is the multimammate mouse Mastomys natalensis.
MSH

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Citrus

A plant genus of the family RUTACEAE. They bear the familiar citrus fruits including oranges, grapefruit, lemons, and limes. There are many hybrids which makes the nomenclature confusing.
MSH

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fertilizující látky ženské

Compounds which increase the capacity to conceive in females.
MSH

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aminofylin

A drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It`s most common use is in bronchial asthma, but it has been investigated for several other applications.
MSH

drug combination that contains theophylline and ethylenediamine; its most common use is in bronchial asthma, but it has been investigated for several other applications.
CSP

A methylxanthine and derivative of theophylline. Aminophylline relaxes smooth muscles, particularly bronchial muscles. This xanthine most likely exerts its effect by inhibiting cAMP or cGMP phosphodiesterases, thereby increasing levels of the second messenger cAMP or cGMP intracellularly. Other mode of actions include an adenosine antagonistic effect on the activity of CD4 lymphocytes and mediator release from mast cells thereby decreasing lung sensitivity to allergens and other substances that cause inflammation. Aminophylline also acts as a CNS stimulant and exerts a positive chronotropic and inotropic effect on the heart.
NCI

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konziliární vyšetření a konzultace

The practice of sending a patient to another program or practitioner for services or advice which the referring source is not prepared to provide.
MSH

practice of sending a patient to another program or practitioner for services or advice which the referring person is not prepared to provide; requesting advice from another person in the field.
CSP

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lecitinacyltransferasa – nedostatek

An autosomal recessively inherited disorder caused by mutation of LECITHIN CHOLESTEROL ACYLTRANSFERASE that facilitates the esterification of lipoprotein cholesterol and subsequent removal from peripheral tissues to the liver. This defect results in low HDL-cholesterol level in blood and accumulation of free cholesterol in tissue leading to a triad of CORNEAL OPACITY, hemolytic anemia (ANEMIA, HEMOLYTIC), and PROTEINURIA.
MSH

disease characterized by abnormally low levels of plasma lecithin cholesterol acyl transferase; clinical manifestations include corneal opacity, anemia, and proteinuria.
CSP

A disorder of lipoprotein metabolism caused by mutations in the LCAT gene. It is characterized by deficiency of the enzyme lecithin cholesterol acyltransferase. It is manifested with corneal opacity, hemolytic anemia, and proteinuria.
NCI

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klinické ošetřovatelství – výzkum

Research carried out by nurses in the clinical setting and designed to provide information that will help improve patient care. Other professional staff may also participate in the research.
MSH

Professional nursing care provided in a research environment. Including management of clinical trials, direct patient care, and research assistance.
NCI

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SUKARRA

Fever: a documented body temperature higher than 38 degrees C., or 100.4 degrees F.
AIR

An abnormal elevation of body temperature, usually as a result of a pathologic process.
MSH

abnormal elevation of body temperature, usually as a result of a pathologic process.
CSP

A fever is a body temperature that is higher than normal. It is not an illness. It is part of your body`s defense against infection. Most bacteria and viruses that cause infections do well at the body`s normal temperature (98.6 F). A slight fever can make it harder for them to survive. Fever also activates your body`s immune system.

Infections cause most fevers. There can be many other causes, including

  • Medicines
  • Heat exhaustion
  • Cancers
  • Autoimmune diseases

Treatment depends on the cause of your fever. Your health care provider may recommend using over-the-counter medicines such as acetaminophen or ibuprofen to lower a very high fever. Adults can also take aspirin, but children with fevers should not take aspirin. It is also important to drink enough liquids to prevent dehydration.


MEDLINEPLUS

A disorder characterized by elevation of the body`s temperature above the upper limit of normal.
NCI

An increase in body temperature above normal (98.6 degrees F), usually caused by disease.
NCI

The elevation of the body`s temperature above the upper limit of normal, usually taken as 37.7 degrees C.
NCI

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amfetaminy

Analogs or derivatives of AMPHETAMINE. Many are sympathomimetics and central nervous system stimulators causing excitation, vasopressin, bronchodilation, and to varying degrees, anorexia, analepsis, nasal decongestion, and some smooth muscle relaxation.
MSH

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rehabilitační centra

Facilities which provide programs for rehabilitating the mentally or physically disabled individuals.
MSH

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Leishmania

genus of flagellate protozoa comprising several species that are pathogenic for humans; organisms have an amastigote and a promastigote stage in their life cycles; genus has been divided into two subgenera: Leishmania leishmania and Leishmania viannia.
CSP

A genus of flagellate protozoa comprising several species that are pathogenic for humans. Organisms of this genus have an amastigote and a promastigote stage in their life cycles. As a result of enzymatic studies this single genus has been divided into two subgenera: Leishmania leishmania and Leishmania viannia. Species within the Leishmania leishmania subgenus include: L. aethiopica, L. arabica, L. donovani, L. enrietti, L. gerbilli, L. hertigi, L. infantum, L. major, L. mexicana, and L. tropica. The following species are those that compose the Leishmania viannia subgenus: L. braziliensis, L. guyanensis, L. lainsoni, L. naiffi, and L. shawi.
MSH

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Clostridium

genus of motile or nonmotile gram positive bacteria of the family Clostridiaceae; many species have been identified with some being pathogenic, occurring in water, soil, and in the intestinal tract of humans and lower animals.
CSP

A genus of motile or nonmotile gram-positive bacteria of the family Clostridiaceae. Many species have been identified with some being pathogenic. They occur in water, soil, and in the intestinal tract of humans and lower animals.
MSH

A genus of gram-positive, obligate anaerobic bacteria in the Firmicutes phylum capable of producing endospores.
NCI

Any bacteria that is not assigned to the species level but can be assigned to the Clostridium genus level.
NCI

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