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glukosafosfátdehydrogenasa

Encoded as 2 alternative isoforms by human housekeeping G6PD Gene (G6PD Family), 514-/560-aa 59-kDa homodimeric or homotetrameric cytosolic Glucose-6-Phosphate Dehydrogenase mainly produces NADPH, an electron donor to oxidizing agents and in biosynthetic reactions. G6PD deficiency may cause jaundice, hemolysis, or non-spherocytic hemolytic anemia. (NCI)
NCI

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Anabolic steroids

a natural or synthetic steroid that promotes bone and muscle growth
CHV

A type of steroid that is used in medicine to repair body tissues and to increase appetite and the growth of muscles. Anabolic steroids are made in the laboratory from testosterone (a male hormone).
NCI

Synthetic derivatives of the male hormone, androgen, that promote tissue growth by increasing the metabolic processes involved with protein synthesis and are used to promote weight gain in wasting diseases. They are used by bodybuilders and athletes to increase muscle mass, strength, and stamina.
NCI

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ostrovy Středozemního moře

Scattered islands in the Mediterranean Sea. The chief islands are the Balearic Islands (belong to Spain; Majorca and Minorca are among these), Corsica (belongs to France), Crete (belongs to Greece), CYPRUS (a republic), the Cyclades, Dodecanese and Ionian Islands (belong to Greece), MALTA (a republic), Sardinia and SICILY (belong to Italy). (From Webster`s New Geographical Dictionary, 1988, p747)
MSH

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komplement 3b

The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and COMPLEMENT C5 CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in IMMUNE ADHERENCE REACTION and enhances PHAGOCYTOSIS. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as COMPLEMENT C3C; COMPLEMENT C3D; C3e; C3f; and C3g.
MSH

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arteria renalis

A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
MSH

branch of the abdominal or ventral aorta which supplies the kidneys, adrenal glands and ureters in vertebrates.
CSP

The main blood vessel that supplies blood to a kidney and its nearby adrenal gland and ureter. There is a renal artery for each kidney.
NCI

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glyceridy

GLYCEROL esterified with FATTY ACIDS.
MSH

glycerol esterified with one or more organic acids, particularly long chain fatty acids.
CSP

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pomocné služby v nemocnici

Those support services other than room, board, and medical and nursing services that are provided to hospital patients in the course of care. They include such services as laboratory, radiology, pharmacy, and physical therapy services.
MSH

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melatonin

A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
MSH

5-methoxy-N-acetyltryptamine, a pineal hormone involved in modulation of skin pigmentation, gonad development, and circadian rhythms.
CSP

a hormone that stimulates color change of the skin and sleep processes in animals
CHV

A hormone made by the pineal gland (tiny organ near the center of the brain). Melatonin helps control the body`s sleep cycle, and is an antioxidant. It is also made in the laboratory and sold as a supplement.
NCI

A recombinant therapeutic analog of melatonin, a natural serotonin-derived indole with antioxidant properties. Melatonin hormone synthesis occurs in the pineal gland and depends on beta-adrenergic receptor function. Melatonin is involved in numerous biological functions: circadian rhythm, sleep, stress response, aging, and immunity. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42346&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42346&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C632″ NCI Thesaurus)
PDQ

A hormone involved in sleep regulatory activity, and a tryptophan-derived neurotransmitter, which inhibits the synthesis and secretion of other neurotransmitters such as dopamine and GABA. Melatonin is synthesized from serotonin intermediate in the pineal gland and the retina where the enzyme 5-hydroxyindole-O-methyltransferase, that catalyzes the last step of synthesis, is found. This hormone binds to and activates melatonin receptors and is involved in regulating the sleep and wake cycles. In addition, melatonin possesses antioxidative and immunoregulatory properties via regulating other neurotransmitters.
NCI

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obsedantně-kompulzivní osobnost

A disorder characterized by an enduring pattern of inflexibility, extreme orderliness, and perfectionism which interfere with efficiency and which may manifest in many different contexts, including work and leisure activities, financial matters, and issues of morality or ethics.
NCI

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Aanbesteding

In a Request for Proposals (RFPs) the Government states work to be undertaken or a problem to be solved. Respondents compete for a common requirement open to all eligible offerors/bidders. Proposals are evaluated using technical and business evaluation criteria and generally involve negotiations. Bids are awarded to the bidder who is responsible and offers the lowest overall price. (from Acquisition Program)
NCI

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glykopeptidy

Proteins which contain carbohydrate groups attached covalently to the polypeptide chain. The protein moiety is the predominant group with the carbohydrate making up only a small percentage of the total weight.
MSH

peptides with covalently attached carbohydrate, usually resulting from biodegradation or laboratory hydrolysis of glycoproteins.
CSP

Peptides that contain carbohydrate moieties (glycans) covalently attached to the side chains of the amino acid residues that constitute the peptide. (Wikipedia)
NCI

A short chain of amino acids (the building blocks of proteins) that has sugar molecules attached to it. Some glycopeptides have been studied for their ability to stimulate the immune system.
NCI

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meningy – nádory

Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.
MSH

A benign or malignant neoplasm that affects the meninges. The majority of the neoplasms arise from meningothelial cells and are called meningiomas. Non-meningothelial cell neoplasms include mesenchymal, non-meningothelial tumors, hemangiopericytomas, and melanocytic lesions.
NCI

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faktory vyvracející (epidemiologie)

Factors that can cause or prevent the outcome of interest, are not intermediate variables, and are not associated with the factor(s) under investigation. They give rise to situations in which the effects of two processes are not separated, or the contribution of causal factors cannot be separated, or the measure of the effect of exposure or risk is distorted because of its association with other factors influencing the outcome of the study.
MSH

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viry respirační syncyciální

A group of viruses in the PNEUMOVIRUS genus causing respiratory infections in various mammals. Humans and cattle are most affected but infections in goats and sheep have also been reported.
MSH

species in the Pneumovirus genus; an important cause of respiratory tract infection in infants.
CSP

A virus that causes respiratory infections with cold-like symptoms.
NCI

A negative-sense, enveloped RNA virus. The virion is variable in shape and size with an average diameter of between 120 and 300 nm.
NCI

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zlato – radioisotopy

Unstable isotopes of gold that decay or disintegrate emitting radiation. Au 185-196, 198-201, and 203 are radioactive gold isotopes.
MSH

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menthol

An alcohol produced from mint oils or prepared synthetically.
MSH

An organic compound made synthetically or obtained from peppermint or mint oils with flavoring and local anesthetic properties. When added to pharmaceuticals and foods, menthol functions as a fortifier for peppermint flavors. It also has a counterirritant effect on skin and mucous membranes, thereby producing a local analgesic or anesthetic effect.
NCI

A substance that comes from mint oils or is made in the laboratory. It is used to relieve itching and to treat problems in the upper respiratory tract. Menthol causes a cooling sensation when eaten or put on the skin and it acts as a mild pain killer. It is found in nasal sprays, cough drops, inhalers, creams, and lotions. It is also used as a flavor in many food and oral hygiene products.
NCI

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konstrukční materiály

Supplies used in building.
MSH

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retina – dysplazie

Congenital, often bilateral, retinal abnormality characterized by the arrangement of outer nuclear retinal cells in a palisading or radiating pattern surrounding a central ocular space. This disorder is sometimes hereditary.
MSH

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štěp – okluze vaskulární

Obstruction of flow in biological or prosthetic vascular grafts.
MSH

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zuby – meziální pohyb

Migration of the teeth toward the midline or forward in the DENTAL ARCH. (From Boucher`s Clinical Dental Terminology, 4th ed)
MSH

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antikoncepční látky postkoitální syntetické

Postcoital contraceptives which owe their effectiveness to synthetic preparations.
MSH

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Réunion

One of the Indian Ocean Islands, east of Madagascar. Its capital is Saint-Denis. It was discovered in 1507 by the Portuguese and claimed by France in 1638. It was first colonized in 1662 as Isle de Bourbon but renamed Reunion in 1793. In 1946 it was made an overseas department of France. The name commemorates the reunion of the revolutionaries from Marseilles with the National Guard in Paris in 1792. (From Webster`s New Geographical Dictionary, 1988, p1011; Room, Brewer`s Dictionary of Names, 1992, p454; French Embassy)
MSH

A country in Southern Africa, occupying an island in the Indian Ocean, east of Madagascar. (NCI)
NCI

A country in Southern Africa, occupying an island in the Indian Ocean, east of Madagascar. (CIA World Factbook 2002)
NCI

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Gray matter

Cell part cluster consisting predominantly of somas of neurons in the brain and the spinal cord.
FMA

gray nervous tissue composed of nerve cell bodies, unmyelinated nerve fibers and supportive tissue.
CSP

The nerve tissue composed of nerve cell bodies, unmyelinated nerve fibers and supportive tissue found in the brain and spinal cord. It is differentiated from the white matter by color of the tissues and the presence of more myelinated nerve cells in the white matter.
NCI

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metamorfóza biologická

Profound physical changes during maturation of living organisms from the immature forms to the adult forms, such as from TADPOLES to frogs; caterpillars to BUTTERFLIES.
MSH

change of an organism`s shape or structure, particularly in the transition between developmental stages in amphibia and various invertebrates.
CSP

A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal`s form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster. [GOC:sensu, ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”, ISBN:0721662544 “Dorland`s Illustrated Medical Dictionary”]
GO

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cord faktory

Toxic glycolipids composed of trehalose dimycolate derivatives. They are produced by MYCOBACTERIUM TUBERCULOSIS and other species of MYCOBACTERIUM. They induce cellular dysfunction in animals.
MSH

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rinosklerom

A granulomatous disease caused by KLEBSIELLA RHINOSCLEROMATIS infection. Despite its name, this disease is not limited to the nose and NASOPHARYNX but may affect any part of the RESPIRATORY TRACT, sometimes with extension to the lip and the skin.
MSH

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guanabenz

An alpha-2 selective adrenergic agonist used as an antihypertensive agent.
MSH

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methemoglobin

compound formed from hemoglobin by oxidation of the ferrous to the ferric state with essentially ionic bonds; a small amount is normally present in the blood but injury or toxic agents can convert a larger proportion of hemoglobin to methemoglobin, which does not function reversibly as an oxygen carrier.
CSP

A product of hemoglobin produced by oxidation of the iron atom from the ferrous to the ferric state.
NCI

A form of hemoglobin found in the blood in small amounts. Unlike normal hemoglobin, methemoglobin cannot carry oxygen. Injury or certain drugs, chemicals, or foods may cause a higher-than-normal amount of methemoglobin to be made. This causes a condition called methemoglobinemia.
NCI

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corpus striatum

Striped gray and white matter consisting of the NEOSTRIATUM and paleostriatum (GLOBUS PALLIDUS). It is located in front of and lateral to the thalamus in each cerebral hemisphere. The gray substance is made up of the CAUDATE NUCLEUS and the lentiform nucleus (the latter consisting of the GLOBUS PALLIDUS and PUTAMEN). The white matter is the internal capsule.
MSH

striped gray and white matter consisting of the neostriatum and paleostriatum (globus pallidus); located in front of and lateral to the thalamus in each cerebral hemisphere; the gray substance is made up of the caudate nucleus and the lentiform nucleus (the latter consisting of the globus pallidus and putamen; the white matter is the internal capsule.
CSP

Striped gray and white matter consisting of the neostriatum and paleostriatum (globus pallidus). It is located in front of and lateral to the thalamus in each cerebral hemisphere. The gray substance is made up of the caudate nucleus and the lentiform nucleus. The white matter is the internal capsule. (MeSH)
NCI

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ribonukleasy

Enzymes that catalyze the hydrolysis of ester bonds within RNA. EC 3.1.-.
MSH

Enzymes that catalyze the hydrolysis of RNA
NCI

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