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Nucleic Acid Hybridization

zipping reaction between complementary DNA or RNA single strands to form a duplex (double stranded) molecule; basis of many techniques for assaying nucleic acid sequence complementarity.
CSP

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hydroxydopaminy

Dopamines with a hydroxy group substituted in one or more positions.
MSH

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Klaustrofobie

An irrational fear of being in a confined space.
NCI

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RNA ribozomální 16S

Constituent of 30S subunit prokaryotic ribosomes containing 1600 nucleotides and 21 proteins. 16S rRNA is involved in initiation of polypeptide synthesis.
MSH

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nervový přenos

The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
MSH

communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
CSP

The neurological system process in which a signal is transmitted through the nervous system by synaptic transmission and the sequential electrochemical polarization and depolarization that travels across the membrane of a nerve cell (neuron) in response to stimulation. [GOC:curators, ISBN:0815316194]
GO

The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. [GOC:jl, MeSH:D009435]
GO

Any process in which a presynaptic cell transfers a signal to a postsynaptic cell, by either release of a neurotransmitter or by passage of an electrical current via specialized channels. This process is essential to all neuronal functions.
NCI

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zdravotní sestry

Professionals qualified by education at an accredited school of nursing and licensed by state law to practice nursing. They provide services to patients requiring assistance in recovering or maintaining their physical or mental health.
MSH

professionals qualified by education at an accredited school of nursing and licensed by state law to practice nursing; provide services to patients requiring assistance in recovering or maintaining their physical or mental health.
CSP

A health professional trained to care for people who are ill or disabled.
NCI

A professional healthcare provider who has graduated from an accredited nursing program, has passed the state exam for licensure, and been registered or licensed to practice by a state authority. Nurses are educationally prepared as functional (LPN/LVN) or professional (RN).
NCI

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os hyoideum

A mobile U-shaped bone that lies in the anterior part of the neck at the level of the third CERVICAL VERTEBRAE. The hyoid bone is suspended from the processes of the TEMPORAL BONES by ligaments, and is firmly bound to the THYROID CARTILAGE by muscles.
MSH

A U-shaped bone supporting the tongue. This bone is located at the base of the tongue and is suspended from the tips of the styloid processes of the temporal bones by the stylohyoid ligaments. (NCI)
NCI

A U-shaped bone supporting the tongue. This bone is located at the base of the tongue and is suspended from the tips of the styloid processes of the temporal bones by the stylohyoid ligaments.
NCI

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klofibrát

A fibric acid derivative used in the treatment of HYPERLIPOPROTEINEMIA TYPE III and severe HYPERTRIGLYCERIDEMIA. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
MSH

fibric acid derivative used in the treatment of hyperlipoproteinemia and hypertriglyceridemia.
CSP

An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized, clofibrate may enhance the conversion of very-low-density lipoprotein (VLDL) to low-density lipoprotein (LDL), decreasing the production of hepatic VLDL, inhibiting cholesterol production, and increasing fecal excretion of neutral sterols. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42108&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42108&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C378″ NCI Thesaurus)
PDQ

An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized, clofibrate may enhance the conversion of very-low-density lipoprotein (VLDL) to low-density lipoprotein (LDL), decreasing the production of hepatic VLDL, inhibiting cholesterol production, and increasing fecal excretion of neutral sterols.
NCI

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2H-benzo(a)chinolizin-2-ol, 2-ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-

Proposed catecholamine depletor.
MSH

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nervosvalové látky

Drugs used for their actions on skeletal muscle. Included are agents that act directly on skeletal muscle, those that alter neuromuscular transmission (NEUROMUSCULAR BLOCKING AGENTS), and drugs that act centrally as skeletal muscle relaxants (MUSCLE RELAXANTS, CENTRAL). Drugs used in the treatment of movement disorders are ANTI-DYSKINESIA AGENTS.
MSH

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výživa a metabolismus – nemoci

A collective term for nutritional disorders resulting from poor absorption or nutritional imbalance, and metabolic disorders resulting from defects in biosynthesis (ANABOLISM) or breakdown (CATABOLISM) of endogenous substances.
MSH

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hyperostóza difuzní idiopatická skeletální

A disease of elderly men characterized by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions.
MSH

A rare degenerative disorder that affects the spine. It is characterized by ossification of ligaments resulting in calcifications along the sides of the spinal vertebrae.
NCI

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Paličkovité prsty

An enlargement of the tips of the fingers or toes and a change in the angle where the nails emerge. It occurs when the amount of soft tissue beneath the nail beds increases. It may be idiopathic, hereditary, or associated with a wide range of diseases, including cardiopulmonary disorders and malignant neoplasms.
NCI

An abnormal enlargement of the terminal phalanges accompanied by increased length-wise curvature of the nails, giving the digits a club-like appearance. Clubbing has been noted with a wide variety of conditions, including pulmonary and cardiac diseases, liver disorders, and disorders of the gastrointestinal tract.
NCI

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rotenon

A botanical insecticide that is an inhibitor of mitochondrial electron transport.
MSH

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neurotensin

A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hypotension in the rat, to stimulate contraction of guinea pig ileum and rat uterus, and to cause relaxation of rat duodenum. There is also evidence that it acts as both a peripheral and a central nervous system neurotransmitter.
MSH

tridecapeptide found in small intestine and brain; induces vasodilation and hypotension and acts as a neurotransmitter in the brain.
CSP

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dermatitida z povolání

A recurrent contact dermatitis caused by substances found in the work place.
MSH

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hypestézie

Absent or reduced sensitivity to cutaneous stimulation.
MSH

Impairment of tactile sensitivity manifesting as partial loss of sensitivity to sensory stimuli.
NCI

Consisting of abnormally decreased sensitivity, particularly to touch.
NCI

An abnormally decreased sensitivity to touch, pressure, or pain.
NCI

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švábi

Insects of the order Dictyoptera comprising several families including Blaberidae, BLATTELLIDAE, Blattidae (containing the American cockroach PERIPLANETA americana), Cryptocercidae, and Polyphagidae.
MSH

insects of the order Dictyoptera comprising several families including Blaberidae, Blattellidae, Blattidae (containing the American cockroach, Periplaneta americana), Cryptocercidae, and Polyphagidae.
CSP

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Rwanda

A republic in eastern Africa, south of UGANDA, east of DEMOCRATIC REPUBLIC OF THE CONGO, west of TANZANIA. Its capital is Kigali. It was formerly part of the Belgian trust territory of Ruanda-Urund.
MSH

A country in Central Africa, east of Democratic Republic of the Congo. (NCI)
NCI

A country in Central Africa, east of Democratic Republic of the Congo. (CIA World Factbook 2002)
NCI

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nikardipin

A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
MSH

1,4-dihydro-2,6-dimethyl-4-nitrophenyl-3, 5-pyridine carboxylic acid methyl-2- methylphenylmethylaminoethyl ester; calcium channel blocker of the nifedipine family; used clinically as a cerebral and coronary vasodilator.
CSP

A synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator.
NCI

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dens axis

The toothlike process on the upper surface of the axis, which articulates with the CERVICAL ATLAS above.
MSH

A bony tooth-like process projecting from the second cervical vertebra. It serves as the structure that supports the rotation of the first cervical vertebra.
NCI

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hypoprotrombinémie

absence or reduced levels of prothrombin in the blood.
CSP

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nízká teplota

Having less heat energy than the object against which it is compared; the absence of heat.
NCI

An absence of warmth or heat or a temperature notably below an accustomed norm.
MSH

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Saline Solution

any aqueous salt solution; usually means normal or physiological saline, which is 0.9% sodium chloride, and is used as a base for culture media and buffers, and as an injection vehicle or control.
CSP

A solution of salt and water.
NCI

A solution of salt and water. Saline usually refers to normal or physiological saline, which is an aqueous solution containing 0.9% sodium chloride.
NCI

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Nippostrongylus

genus of intestinal nematode parasites belonging to the superfamily Heligmosomatoidea, which commonly occurs in rats but has been experimentally transmitted to other rodents and rabbits; infection is usually through the skin.
CSP

A genus of intestinal nematode parasites belonging to the superfamily HELIGMOSOMATOIDEA, which commonly occurs in rats but has been experimentally transmitted to other rodents and rabbits. Infection is usually through the skin.
MSH

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oligodeoxyribonukleotidy

A group of deoxyribonucleotides (up to 12) in which the phosphate residues of each deoxyribonucleotide act as bridges in forming diester linkages between the deoxyribose moieties.
MSH

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krevní skupiny – systém I

A blood group related both to the ABO and P systems that includes several different antigens found in most people on erythrocytes, in milk, and in saliva. The antibodies react only at low temperatures.
MSH

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zlato koloidní

A suspension of metallic gold particles.
MSH

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soli

Substances produced from the reaction between acids and bases; compounds consisting of a metal (positive) and nonmetal (negative) radical. (Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

any compound of a base and an acid; any compound of an acid some of whose replaceable hydrogen atoms have been substituted.
CSP

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dusík – radioisotopy

Unstable isotopes of nitrogen that decay or disintegrate emitting radiation. N atoms with atomic weights 12, 13, 16, 17, and 18 are radioactive nitrogen isotopes.
MSH

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