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hepatitida virová zvířat

INFLAMMATION of the LIVER in animals due to viral infection.
MSH

not restricted to hepatitis caused by hepatitis viruses; use also for hepatitis caused by other viruses in animals.
CSP

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ochranné prostředky

Devices designed to provide personal protection against injury to individuals exposed to hazards in industry, sports, aviation, or daily activities.
MSH

equipment specifically designed to enhance the safety of procedures, work environments, or other equipment; e.g., seat belts, air bags, radiation shields, noise mufflers, air filtering systems, etc.
CSP

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molekuly buněčné adheze neuronové

Surface ligands that mediate cell-to-cell adhesion and function in the assembly and interconnection of the vertebrate nervous system. These molecules promote cell adhesion via a homophilic mechanism. These are not to be confused with NEURAL CELL ADHESION MOLECULES, now known to be expressed in a variety of tissues and cell types in addition to nervous tissue.
MSH

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mukopolysacharidóza III

Mucopolysaccharidosis characterized by heparitin sulfate in the urine, progressive mental retardation, mild dwarfism, and other skeletal disorders. There are four clinically indistinguishable but biochemically distinct forms, each due to a deficiency of a different enzyme.
MSH

mucopolysaccharidosis characterized by heparin sulfate in the urine, progressive mental retardation, mild dwarfism, and other skeletal disorders.
CSP

A rare autosomal recessive lysosomal storage disease affecting the metabolism of mucopolysaccharides. Signs and symptoms include behavioral changes, sleep disorders, mental developmental delays, and seizures.
NCI

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acetylmuramyl-alanyl-isoglutamin

Peptidoglycan immunoadjuvant originally isolated from bacterial cell wall fragments; also acts as pyrogen and may cause arthritis; stimulates both humoral and cellular immunity.
MSH

A naturally occurring component of bacterial cell walls that has the capacity to activate macrophages.
NCI

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HERPES SINPLEXA( ESKL. BEGIA F85; GENITALA X90, Y72)

A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
MSH

infection caused by the herpes simplex virus; affects the skin and nervous system; produces small temporary (but sometimes painful) blisters on the skin and mucous membranes.
CSP

Herpes is an infection that is caused by a herpes simplex virus (HSV). Oral herpes causes cold sores around the mouth or face. Genital herpes affects the genitals, buttocks or anal area. Genital herpes is a sexually transmitted disease (STD). It affects the genitals, buttocks or anal area. Other herpes infections can affect the eyes, skin, or other parts of the body. The virus can be dangerous in newborn babies or in people with weak immune systems.

There are two types of HSV:

  • HSV type 1 most commonly causes cold sores. It can also cause genital herpes.
  • HSV type 2 is the usual cause of genital herpes, but it also can infect the mouth.

HSV spreads direct contact. Some people have no symptoms. Others get sores near the area where the virus has entered the body. They turn into blisters, become itchy and painful, and then heal.

Most people have outbreaks several times a year. Over time, you get them less often. Medicines to help your body fight the virus can help lessen symptoms and decrease outbreaks.


MEDLINEPLUS

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Proteus vulgaris

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in soil, fecal matter, and sewage. It is an opportunistic pathogen and causes cystitis and pyelonephritis.
MSH

Any bacterial organism that can be assigned to the species Proteus vulgaris.
NCI

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bezbuněčný systém

A fractionated cell extract that maintains a biological function. A subcellular fraction isolated by ultracentrifugation or other separation techniques must first be isolated so that a process can be studied free from all of the complex side reactions that occur in a cell. The cell-free system is therefore widely used in cell biology. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p166)
MSH

experimental condition created by disrupting cells with homogenization, sonication, detergents, or other treatment, leaving intracellular components exposed to controlled manipulation of the medium.
CSP

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Muridae

A family of the order Rodentia containing 250 genera including the two genera Mus (MICE) and Rattus (RATS), from which the laboratory inbred strains are developed. The fifteen subfamilies are SIGMODONTINAE (New World mice and rats), CRICETINAE, Spalacinae, Myospalacinae, Lophiomyinae, ARVICOLINAE, Platacanthomyinae, Nesomyinae, Otomyinae, Rhizomyinae, GERBILLINAE, Dendromurinae, Cricetomyinae, MURINAE (Old World mice and rats), and Hydromyinae.
MSH

Taxonomic family which includes mice, rats, and gerbils.
NCI

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aklarubicin

An anthracycline produced by Streptomyces galilaeus. It has potent antineoplastic activity.
MSH

An oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39131&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39131&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C202″ NCI Thesaurus)
PDQ

An oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin.
NCI

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hexestrol

A synthetic estrogen that has been used as a hormonal antineoplastic agent.
MSH

A synthetic hydrogenated derivative of diethylstilbestrol (DES). Hexestrol exhibits strong affinity for estrogen receptors that are overexpressed in some types of cancers. When conjugated with a neoplastic drug, hexestrol may selectively concentrate the cytotoxic agent in estrogen receptor-rich tumors. This agent may also be mutagenic. (NCI04)
NCI

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pseudogeny

Genes bearing close resemblance to known genes at different loci, but rendered non-functional by additions or deletions in structure that prevent normal transcription or translation. When lacking introns and containing a poly-A segment near the downstream end (as a result of reverse copying from processed nuclear RNA into double-stranded DNA), they are called processed genes.
MSH

inactive but stable components of the genome derived from mutations of ancestral genes; probably account for a significant amount of the so-called “junk DNA” that comprises most of the genome of eukaryotes.
CSP

Nonfunctional DNA sequences that are very similar to the sequences of known genes. Many seem to have arisen as functional gene duplications that subsequently underwent mutation and loss of function. Others are structurally similar to mRNA and seem to have arisen by a reverse transcription event followed by integration into the genome. Some pseudogenes are transcribed and may play a role in regulation of its homologous gene.
NCI

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centrifugace izopyknická

A technique used to separate particles according to their densities in a continuous density gradient. The sample is usually mixed with a solution of known gradient materials and subjected to centrifugation. Each particle sediments to the position at which the gradient density is equal to its own. The range of the density gradient is usually greater than that of the sample particles. It is used in purifying biological materials such as proteins, nucleic acids, organelles, and cell types.
MSH

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hořčičné sloučeniny

Strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups. Although otherwise structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA. They are generally highly toxic but include among their number many widely used and effective antineoplastic agents.
MSH

strong alkylating and immunosuppressive agents whose biological activity is based on the presence of bis(2-chloroethyl)- groups; although structurally diverse, the compounds have in common the capacity to contribute alkyl groups to DNA; they are generally highly toxic but include among their number many widely used and effective antineoplastic agents; use this term to cover the chemical warfare agent mustard gas.
CSP

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aktinium

Actinium. A trivalent radioactive element and the prototypical member of the actinide family. It has the atomic symbol Ac, atomic number 89, and atomic weight 227.0278. Its principal isotope is 227 and decays primarily by beta-emission.
MSH

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kyčel – fraktury

Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).
MSH

breaks or rupture in bones or cartilages of the hip; for fractures of the femoral shaft below the subtrochanteric region use LIMB FRACTURE.
CSP

A finding of traumatic injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken.
NCI

Traumatic or pathological injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken. Symptoms include pain in the hip or groin, bruising and swelling in and around the hip area. The injured hip is turned outward and the leg appears shorter on that side.
NCI

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psychoakustika

The science pertaining to the interrelationship of psychologic phenomena and the individual`s response to the physical properties of sound.
MSH

science pertaining to the interrelationship of psychologic phenomena and the response to the physical properties of sound.
CSP

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aquaeductus cerebri

Narrow channel in the mesencephalon that connects the third and fourth ventricles.
MSH

A channel that connects the third and fourth ventricles of the brain.
NCI

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Mycoplasmatales

order of highly pleomorphic, gram negative bacteria including both pathogenic and saprophytic species.
CSP

An order of highly pleomorphic, gram-negative bacteria including both pathogenic and saprophytic species.
MSH

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protein přenášející acyl

Consists of a polypeptide chain and 4`-phosphopantetheine linked to a serine residue by a phosphodiester bond. Acyl groups are bound as thiol esters to the pantothenyl group. Acyl carrier protein is involved in every step of fatty acid synthesis by the cytoplasmic system.
MSH

small subunits of mitochondrial fatty acid synthase complex that covalently bind the growing fatty acid and carry it through the course of synthesis.
CSP

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histokompatibilita – antigeny

A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection.
MSH

group of antigens that includes major histocompatibility antigens, genetically determined by the major histocompatibility complex, which determine tissue type for transplantation and cause allograft rejection; and minor histocompatibility antigens, systems of allelic alloantigens that can cause weak transplant rejection.
CSP

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psychofyziologické poruchy

A group of disorders characterized by physical symptoms that are affected by emotional factors and involve a single organ system, usually under AUTONOMIC NERVOUS SYSTEM control. (American Psychiatric Glossary, 1988)
MSH

characterized by physical symptoms and demonstrable structural or physiological changes in which emotional factors are believed to play a major etiologic role.
CSP

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cer – isotopy

Stable cerium atoms that have the same atomic number as the element cerium, but differ in atomic weight. Ce-136, 138, and 142 are stable cerium isotopes.
MSH

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myoklonus

Involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. This condition may be a feature of some CENTRAL NERVOUS SYSTEM DISEASES; (e.g., EPILEPSY, MYOCLONIC). Nocturnal myoclonus is the principal feature of the NOCTURNAL MYOCLONUS SYNDROME. (From Adams et al., Principles of Neurology, 6th ed, pp102-3).
MSH

shock-like contraction of a portion of a muscle, an entire muscle, or a group of muscles; may be part of a disease process or a normal physiological response.
CSP

A sudden, brief, strong contraction of a muscle or group of muscles that cannot be controlled.
NCI

A sudden, involuntary contraction of a muscle or group of muscles; these movements may develop as a symptom of a number of neurological diseases including epilepsy, Parkinson`s disease, Alzheimer`s disease, or Creutzfeldt-Jacob disease.
NCI

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adenosindifosfát

Adenosine 5`-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5`-position.
MSH

adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5`-position that is converted to ATP for energy for storage.
CSP

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HIV séroprevalence

Studies of the number of cases where human immunodeficiency virus (HIV) is present in a specific population at a designated time. The presence in a given individual is determined by the finding of HIV antibodies in the serum (HIV SEROPOSITIVITY).
MSH

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veřejné zdravotnictví – řízení

Management of public health organizations or agencies.
MSH

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chalazion

A non-neoplastic cyst of the MEIBOMIAN GLANDS of the eyelid.
MSH

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HIPOTIROIDISMOA/MISOEDEMA

A condition characterized by a dry, waxy type of swelling (EDEMA) with abnormal deposits of MUCOPOLYSACCHARIDES in the SKIN and other tissues. It is caused by a deficiency of THYROID HORMONES. The skin becomes puffy around the eyes and on the cheeks. The face is dull and expressionless with thickened nose and lips.
MSH

condition characterized by a dry, waxy type of swelling with abnormal deposits of mucin in the skin and other tissues; it is produced by a functional insufficiency of the thyroid gland, resulting in deficiency of thyroid hormone.
CSP

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poruchy přizpůsobení

Maladaptive reactions to identifiable psychosocial stressors occurring within a short time after onset of the stressor. They are manifested by either impairment in social or occupational functioning or by symptoms (depression, anxiety, etc.) that are in excess of a normal and expected reaction to the stressor.
MSH

A condition in which a person responds to a stressful event (such as an illness, job loss, or divorce) with extreme emotions and actions that cause problems at work and home.
NCI

A category of psychiatric disorders which are characterized by emotional or behavioral symptoms that develop within 3 months of a stressor and do not persist for more than an additional 6 months after the stressor is no longer present.
NCI

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