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plutonium

Plutonium. A naturally radioactive element of the actinide metals series. It has the atomic symbol Pu, atomic number 94, and atomic weight 242. Plutonium is used as a nuclear fuel, to produce radioisotopes for research, in radionuclide batteries for pacemakers, and as the agent of fission in nuclear weapons.
MSH

radioactive element of the actinide metals series; atomic symbol Pu, atomic number 94, and atomic weight 242; used as a nuclear fuel, to produce radioisotopes for research, in radionuclide batteries for pacemakers, and as an agent of fission in nuclear weapons.
CSP

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oxid dusnatý

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
MSH

NO; originally found as an intercellular messenger molecule in vascular smooth muscle, where it has a relaxant, vasodilatory effect; formed by oxidation of arginine with citrulline as side product; in nervous tissue, may be part of glutamate-calcium-cGMP signal transduction system.
CSP

name of an inorganic chemical
CHV

An unstable free-radical gas which reacts rapidly with oxygen to form nitrogen oxides. Water soluble, NO is produced normally in numerous tissues and is considered to be a mediator of cell-to cell communication; it functions in numerous processes including vasodilation, inflammation, and neurotransmission. (NCI04)
NCI

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trávení

The process of breakdown of food for metabolism and use by the body.
MSH

process of breakdown of food for metabolism and use by the body.
CSP

The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. [GOC:isa_complete, ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

The process of breaking down food into substances the body can use for energy, tissue growth, and repair.
NCI

The process or act of converting food into chemical substances that can be absorbed and assimilated.
NCI

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tantal

Tantalum. A rare metallic element, atomic number 73, atomic weight 180.948, symbol Ta. It is a noncorrosive and malleable metal that has been used for plates or disks to replace cranial defects, for wire sutures, and for making prosthetic devices. (Dorland, 28th ed)
MSH

rare metallic element, symbol Ta, atomic number 73; noncorrosive and malleable metal used for plates or disks to replace cranial defects, for wire sutures, and for prosthetic appliances.
CSP

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ichtyóza

Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.
MSH

A group of inherited or acquired skin disorders characterized by a dry, thickened, and scaly skin. The skin changes range from mild to severe.
NCI

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lůžka

Equipment on which one may lie and sleep, especially as used to care for the hospital patient.
MSH

A structure that permits a subject to recline; it can be used for sleeping or for positioning a subject for a procedure.
NCI

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Rothmundův-Thomsonův syndrom

A rare inherited disorder that affects the skin and many other parts of the body, including the bones, eyes, nose, hair, nails, teeth, testes, and ovaries. People with Rothmund-Thomson syndrome have an increased risk of osteosarcoma (bone cancer).
NCI

An autosomal recessive inherited syndrome usually caused by mutations in the RECQL4 gene. It is characterized by poikilodermatous skin changes, sparse hair, cataracts, small stature, skeletal abnormalities, and an increased predisposition to cancer, particularly osteosarcoma.
NCI

An autosomal recessive syndrome occurring principally in females, characterized by the presence of reticulated, atrophic, hyperpigmented, telangiectatic cutaneous plaques, often accompanied by juvenile cataracts, saddle nose, congenital bone defects, disturbances in the growth of HAIR; NAILS; and TEETH; and HYPOGONADISM.
MSH

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nitrosace

Conversion into nitroso compounds. An example is the reaction of nitrites with amino compounds to form carcinogenic N-nitrosamines.
MSH

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dihydroxyacetonfosfát

An important intermediate in lipid biosynthesis and in glycolysis.
MSH

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technecium 99mTc-pertechnát

A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in the gastrointestinal system, cardiovascular and cerebral circulation, brain, thyroid, and joints.
MSH

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Illinois

A state in the central midwest United States. Its capital is Springfield.
NCI

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benigní hypertrofie prostaty

A benign (noncancerous) condition in which an overgrowth of prostate tissue pushes against the urethra and the bladder, blocking the flow of urine.
NCI

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poly T

A group of thymine nucleotides in which the phosphate residues of each thymine nucleotide act as bridges in forming diester linkages between the deoxyribose moieties.
MSH

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neverbální komunikace

Transmission of emotions, ideas, and attitudes between individuals in ways other than the spoken language.
MSH

communicative behavior not involving language; e.g., hand gestures or facial expression.
CSP

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dinitolmid

A coccidiostat for poultry.
MSH

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obrovskobuněčná arteritida

A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)
MSH

Giant cell arteritis is a disorder that causes inflammation of arteries of the scalp, neck, and arms. The inflammation narrows the arteries, which keeps blood from flowing well. Giant cell arteritis often occurs with another disorder called polymyalgia rheumatica. Both disorders are more common in women than in men. They almost always affect people over the age of 50.

Early symptoms of giant cell arteritis resemble the flu: fatigue, loss of appetite, and fever. Other symptoms include headaches, pain and tenderness over the temples, double vision or visual loss, dizziness, and problems with coordination and balance. You may also have pain in your jaw and tongue.

Your doctor will make the diagnosis based on your medical history, symptoms, and physical examination. There is no single test to diagnose giant cell arteritis, but you may have tests that measure inflammation.

Treatment is usually with corticosteroids. Early treatment is important; otherwise there is a risk of permanent vision loss or stroke. However, when properly treated, giant cell arteritis rarely comes back.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases


MEDLINEPLUS

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imunizace

Deliberate stimulation of the host`s immune response. ACTIVE IMMUNIZATION involves administration of ANTIGENS or IMMUNOLOGIC ADJUVANTS. PASSIVE IMMUNIZATION involves administration of IMMUNE SERA or LYMPHOCYTES or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).
MSH

deliberate induction of host immunity.
CSP

The introduction of an immunogen with the intent of stimulating an immune response, aimed at preventing subsequent infections by more viable agents.


HL7V3.0

A technique used to cause an immune response that results in resistance to a specific disease, especially an infectious disease.
NCI

Shots may hurt a little… but the diseases they can prevent can hurt a lot more! Immunization shots, or vaccinations, are essential. They protect against things like measles, mumps, rubella, hepatitis B, polio, diphtheria, tetanus and pertussis (whooping cough). Immunizations are important for adults as well as for children. Here`s why.

Your immune system helps your body fight germs by producing substances to combat them. Once it does, the immune system "remembers" the germ and can fight it again. Vaccines contain germs that have been killed or weakened. When given to a healthy person, the vaccine triggers the immune system to respond and thus build immunity.

Before vaccines, people became immune only by actually getting a disease and surviving it. Immunizations are an easier and less risky way to become immune.

NIH: National Institute of Allergy and Infectious Diseases


MEDLINEPLUS

Inoculating an individual with either killed or live agents to prevent contraction of a disease.
NCI

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benzopyrenhydroxylasa

A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.
MSH

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polyisoprenylfosfátové oligosacharidy

These compounds function as activated glycosyl carriers in the biosynthesis of glycoproteins and glycophospholipids. Include the pyrophosphates.
MSH

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Diphyllobothrium

A genus of tapeworm containing several species which occurs in the intestine of fish, birds, and mammals including man. Infection in humans is usually by eating uncooked fish. The larval stage is known as SPARGANUM.
MSH

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terfenylové sloučeniny

Compounds consisting of benzene rings linked to each other in either ortho, meta or para positions. Permitted are any substitutions, but ring fusion to any of the benzene rings is not allowed.
MSH

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imunoglobuliny – kappa-řetězce

Immunoglobulin Light Chain Kappa is one of two Ig light chain types. Each Ig molecule is typically composed of two heavy chains and two light chains. Ig kappa light chains contain a variable and a constant region. Kappa light chains are encoded by multiple V, J, and C gene segments, which are separated in the genomes of cells undifferentiated with regard to antibody gene expression. Diversity in the kappa light chain V region arises during differentiation of an activated (kappa-type) antibody-producing B-cell from variable recombination of kappa V genes with kappa J genes and somatic point mutation, which plays a major role in antibody diversity. (from OMIM and NCI)
NCI

One of the types of light chains of the immunoglobulins with a molecular weight of approximately 22 kDa.
MSH

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beta částice

High energy POSITRONS or ELECTRONS ejected from a disintegrating atomic nucleus.
MSH

An electron or positron. (Dr. Joseph A. Thie)
NCI

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polysacharidy

linear or branched chain structure containing many sugar molecules linked by glycosidic bonds.
CSP

A large carbohydrate molecule. It contains many small sugar molecules that are joined chemically.
NCI

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infekční nemoci – vektory

Invertebrates or non-human vertebrates which transmit infective organisms from one host to another.
MSH

index also with the most specific vector organism name available; see RTs for specific organisms.
CSP

An invertebrate animal (e.g., tick, mite, mosquito, bloodsucking fly) capable of transmitting an infectious agent among vertebrates.
NCI

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tetrahydrofoláty

Compounds based on 5,6,7,8-tetrahydrofolate.
MSH

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impulzivní poruchy

Disorders whose essential features are the failure to resist an impulse, drive, or temptation to perform an act that is harmful to the individual or to others. Individuals experience an increased sense of tension prior to the act and pleasure, gratification or release of tension at the time of committing the act.
MSH

A category of psychiatric disorders whose essential features are the failure to resist an impulse to perform an act that is harmful to the individual or to others. Individuals typically experience an increased sense of tension prior to the act and then pleasure, gratification or release of tension at the time of committing the act.
NCI

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bibliografie národní

A bibliography which lists all the books and other publications published, or distributed in significant quantity, in a particular country. Sometimes the term is used with respect to the new publications published within a specific period, and sometimes with respect to all those published within a lengthy period of many years. It is also used to indicate a bibliography of publications about a country (whether written by its nationals or not) and those written in the language of the country as well as those published in it. (Harrod`s Librarians` Glossary, 7th ed)
MSH

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hydroxymethylbilansynthasa

An enzyme that catalyzes the tetrapolymerization of the monopyrrole PORPHOBILINOGEN into the hydroxymethylbilane preuroporphyrinogen (UROPORPHYRINOGENS) in several discrete steps. It is the third enzyme in the 8-enzyme biosynthetic pathway of HEME. In humans, deficiency in this enzyme encoded by HMBS (or PBGD) gene results in a form of neurological porphyria (PORPHYRIA, ACUTE INTERMITTENT). This enzyme was formerly listed as EC 4.3.1.8
MSH

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diuretika

agents that promote the excretion of urine through their effects on kidney function.
CSP

A drug that increases the production of urine.
NCI

a drug that increases urinary elimination
CHV

A class of agents that promotes the formation of urine by the kidney. Via various mechanism of actions, diuretics retain water in urine, thus provides a means of forced diuresis.
NCI

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