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radioimunosorpční test

Radioimmunoassay of proteins using antibody coupled to an immunosorbent.
MSH

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meskalin

Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church.
MSH

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granuloma gangraenescens

A condition that is characterized by inflammation, ulceration, and perforation of the nose and the PALATE with progressive destruction of midline facial structures. This syndrome can be manifested in several diseases including the nasal type of EXTRANODAL NK-T-CELL LYMPHOMA and WEGENER GRANULOMATOSIS.
MSH

An aggressive, progressive, and destructive lesion affecting the nasal cavities, paranasal sinuses, and the palate. The vast majority of cases are malignant lymphoproliferations affecting the midline of the face in patients with nasal type extranodal NK/T-cell lymphoma.
NCI

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alylisopropylacetamid

An allylic compound that acts as a suicide inactivator of CYTOCHROME P450 by covalently binding to its heme moiety or surrounding protein.
MSH

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chromatografie kapalinová

Chromatographic techniques in which the mobile phase is a liquid.
MSH

separation technique in which the moving stage is a liquid and the stationary stage is a solid or liquid on a solid support; components of a mixture in solution are selectively adsorbed.
CSP

A type of chromatography in which separation of a mixture is achieved by passing a sample in a stream of liquid solvent through some form of material that will provide resistance by virtue of chemical interactions between the components of the sample and the material.
NCI

Chromatography, Liquid


HL7V3.0

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Rana catesbeiana

A species of the family Ranidae (true frogs). The only anuran properly referred to by the common name “bullfrog”, it is the largest native anuran in North America.
MSH

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metaloporfyriny

Porphyrins which are combined with a metal ion. The metal is bound equally to all four nitrogen atoms of the pyrrole rings. They possess characteristic absorption spectra which can be utilized for identification or quantitative estimation of porphyrins and porphyrin-bound compounds.
MSH

compound of a metal with a porphyrin; metal is bound equally to all four nitrogen atoms of the pyrrole rings.
CSP

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růstová ploténka

The area between the EPIPHYSIS and the DIAPHYSIS within which bone growth occurs.
MSH

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alprazolam

A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of PANIC DISORDERS, with or without AGORAPHOBIA, and in generalized ANXIETY DISORDERS. (From AMA Drug Evaluations Annual, 1994, p238)
MSH

8-chloro-1-methyl-6-phenyl-s-triazolo benzodiazepine, has both antidepressant and anxiolytic properties; possible efficacy in alcohol withdrawal therapy; abuse can lead to habituation or addiction.
CSP

a drug used to treat anxiety disorders and panic attacks
CHV

A drug used to treat anxiety disorders and panic attacks. It is being studied in the treatment of nausea and vomiting caused by some cancer treatments. It is a type of benzodiazepine.
NCI

A triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. Alprazolam binds to a specific site distinct from the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) binding site on the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic, thalamic and hypothalamic regions of the central nervous system (CNS). This binding causes an allosteric modification of the receptor and enhances the affinity of GABA to the receptor leading to an increase in the frequency of chloride-channel opening events. This leads to an increase in chloride ion conductance, neuronal hyperpolarization, inhibition of the action potential and leads to a decrease in neuronal excitability. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39659&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39659&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C227″ NCI Thesaurus)
PDQ

A triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. Alprazolam binds to a specific site distinct from the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) binding site on the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic, thalamic and hypothalamic regions of the central nervous system (CNS). This binding causes an allosteric modification of the receptor and enhances the affinity of GABA to the receptor leading to an increase in the frequency of chloride-channel opening events. This leads to an increase in chloride ion conductance, neuronal hyperpolarization, inhibition of the action potential and leads to a decrease in neuronal excitability.
NCI

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chromozómy lidské, pár 1

A specific pair of human chromosomes in group A (CHROMOSOMES, HUMAN, 1-3) of the human chromosome classification.
MSH

The designation for each member of the largest human autosomal chromosome pair. Chromosome 1 spans about 247 million nucleotide base pairs and represents about 8% of the total DNA in normal diploid cells.
NCI

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krysy

The common name for the genus Rattus.
MSH

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methamfetamin

A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.
MSH

sympathomimetic amine closely related chemically to both amphetamine and ephedrine, with actions similar to those of amphetamine; abuse may lead to dependence.
CSP

An amphetamine with central nervous system (CNS) stimulating activity. Methamphetamine acts by both facilitating the release of catecholamines, particularly noradrenaline, dopamine and serotonin, from nerve terminals in the brain and by inhibiting their uptake. This leads to an increase in synaptic concentration of these neurotransmitters and results in increased stimulation of postsynaptic receptors.
NCI

Methamphetamine is a very addictive stimulant drug. It can be smoked, injected, inhaled or taken by mouth. It has many street names, such as speed, meth, and chalk. Methamphetamine hydrochloride, the crystal form inhaled by smoking, is referred to as ice, crystal, glass and tina.

Methamphetamine affects the brain and can create feelings of pleasure, increase energy and elevate mood. Abusers may become addicted quickly, needing higher doses more often. Adverse health effects include irregular heartbeat, increased blood pressure and a variety of psychological problems. Long-term effects may include severe mental disorders, memory loss and severe dental problems.

NIH: National Institute on Drug Abuse


MEDLINEPLUS

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Guernsey

The second largest of the Channel Islands in the English Channel. It covers about 30 square miles and is where the Guernsey breed of cattle originated. The name is Scandinavian, Grani`s island (ey means island). (From Webster`s New Geographical Dictionary, 1988, p474 & Room, Brewer`s Dictionary of Names, 1992, p222)
MSH

A British Crown dependency in the English Channel off the coast of Normandy.
NCI

The island of Guernsey and the other Channel Islands represent the last remnants of the medieval Dukedom of Normandy, which held sway in both France and England. Guernsey is a British crown dependency, but is not part of the UK. (NCI)
NCI

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ambulantní péče

Health care services provided to patients on an ambulatory basis, rather than by admission to a hospital or other health care facility. The services may be a part of a hospital, augmenting its inpatient services, or may be provided at a free-standing facility.
MSH

services rendered by members of the health profession (or under their supervision) for the benefit of patients who come to the hospital or clinic for diagnosis or treatment but do not occupy a bed.
CSP

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chylomikrony

A class of lipoproteins that carry dietary CHOLESTEROL and TRIGLYCERIDES from the SMALL INTESTINE to the tissues. Their density (0.93-1.006 g/ml) is the same as that of VERY-LOW-DENSITY LIPOPROTEINS.
MSH

class of lipoproteins that carry dietary cholesterol and triglycerides from the small intestines to the tissues.
CSP

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receptory cyklického AMP

Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes which influence the behavior of cells. The best characterized cyclic AMP receptors are those of the slime mold Dictyostelium discoideum. The transcription regulator CYCLIC AMP RECEPTOR PROTEIN of prokaryotes is not included nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.
MSH

cell surface receptor found in slime mold Dictyostelium discoideum, where cyclic AMP functions both intra- and extra-cellularly; or, the CRP of E. coli and other systems, a cystolic, DNA-binding protein of the steroid receptor type.
CSP

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methoxamin

An alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION.
MSH

adrenergic agent used for its vasopressor effect to support, restore or maintain blood pressure during anesthesia, and in treatment of paroxysmal supraventricular tachycardia.
CSP

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Haemophilus influenzae

species of Haemophilus found on the mucous membranes of humans and a variety of animals; the species is further divided into biotypes I through VIII.
CSP

A species of HAEMOPHILUS found on the mucous membranes of humans and a variety of animals. The species is further divided into biotypes I through VIII.
MSH

A species of facultatively anaerobic or aerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is nonmotile, catalase and oxidase positive, porphyrin negative, requires both X and V factors to grow in culture, and may be encapsulated or nonencapsulated. H. influenzae is an opportunistic pathogen causing a wide variety of infections including osteomyelitis, meningitis, conjunctivitis and pneumonia.
NCI

Any bacterial organism that can be assigned to the species Haemophilus influenzae.
NCI

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amikacin

A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.
MSH

An antibiotic drug used to treat infection. It belongs to the family of drugs called aminoglycoside antibiotics.
NCI

A broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically locking 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and , misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used in short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria.
NCI

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citalopram

A furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.
MSH

selective neuronal serotonin reuptake inhibitor and a clinically effective antidepressant with tolerable side effects; effective in reducing ethanol uptake in alcoholics.
CSP

a kind of antidepressant drug
CHV

A drug used to treat depression. It belongs to the families of drugs called antidepressant agents and selective serotonin reuptake inhibitors (SSRIs).
NCI

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receptory prolaktinu

Labile proteins on or in prolactin-sensitive cells that bind prolactin initiating the cells` physiological response to that hormone. Mammary casein synthesis is one of the responses. The receptors are also found in placenta, liver, testes, kidneys, ovaries, and other organs and bind and respond to certain other hormones and their analogs and antagonists. This receptor is related to the growth hormone receptor.
MSH

The Prolactin Receptor binds prolactin, initiating the cellular response to the hormone. The receptor is found in breast, placenta, liver, testes, kidneys, ovaries, and other organs. The prolactin receptor is homologous to members of the cytokine receptor superfamily, such as GHR, IL2R, IL3R, IL4R, IL6R, IL7R, EPOR, and GMCSFR. PRLR isoforms differ in the length of their cytoplasmic domains. The short form acts as a dominant-negative inhibitor, forming inactive heterodimers that inhibit Janus kinase 2 activation. (from OMIM 176761 and NCI)
NCI

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methylortuťné sloučeniny

organic compounds in which mercury is attached to a methyl group.
CSP

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ruka – deformity

Alterations or deviations from normal shape or size which result in a disfigurement of the hand.
MSH

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aminoglykosidy

Glycosylated compounds in which there is an amino substituent on the glycoside. Some of them are clinically important ANTIBIOTICS.
MSH

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duchovenstvo

Ordained individuals who perform spiritual and/or religious functions.
NCI

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Recurrence

To come back or to return.
NCI

The return of a sign, symptom, or disease after a remission.
CHV

Happening again (especially at regular intervals).
NCI

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Mexiko

North American country south of the United States of America.
CSP

A country in Central America, bordering the Caribbean Sea and the Gulf of Mexico, between Belize and the US and bordering the North Pacific Ocean, between Guatemala and the US. (NCI)
NCI

Description:Realm code for use of Mexico


HL7V3.0

A country in Central America, bordering the Caribbean Sea and the Gulf of Mexico, between Belize and the US and bordering the North Pacific Ocean, between Guatemala and the US. (CIA World Factbook 2002)
NCI

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ZEFALEA (ESKL.DOLOR R09,MIGRANA N89)

The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
MSH

pain in the cranial region that may occur as an isolated and benign symptom or as a manifestation of a wide variety of conditions.
CSP

Oh my aching head! Nearly everyone has had a headache. The most common type of headache is a tension headache. Tension headaches are due to tight muscles in your shoulders, neck, scalp and jaw. They are often related to stress, depression or anxiety. You are more likely to get tension headaches if you work too much, don`t get enough sleep, miss meals or use alcohol.

Other common types of headaches include migraines, cluster headaches and sinus headaches. Most people can feel much better by making lifestyle changes, learning ways to relax and taking pain relievers.

Headaches can have many causes, but serious causes of headaches are rare. Sometimes headaches warn of a more serious disorder. Let your health care provider know if you have sudden, severe headaches. Get medical help right away if you have a headache after a blow to your head, or if you have a headache along with a stiff neck, fever, confusion, loss of consciousness or pain in the eye or ear.

NIH: National Institute of Neurological Disorders and Stroke


MEDLINEPLUS

A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve.
NCI

Pain in various parts of the head, not confined to the area of distribution of any nerve.
NCI

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Infekce amniové dutiny

Inflammation of the amnion.
NCI

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Clonorchis sinensis

A species of trematode flukes of the family Opisthorchidae. Many authorities consider this genus belonging to Opisthorchis. It is common in China and other Asiatic countries. Snails and fish are the intermediate hosts.
MSH

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