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meskalin

Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church.
MSH

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pyémie

Septicemia caused by pyogenic microorganisms (e.g., STAPHYLOCOCCUS; BACILLUS), resulting in the formation of secondary foci of SUPPURATION and multiple ABSCESSES.
MSH

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granuloma gangraenescens

A condition that is characterized by inflammation, ulceration, and perforation of the nose and the PALATE with progressive destruction of midline facial structures. This syndrome can be manifested in several diseases including the nasal type of EXTRANODAL NK-T-CELL LYMPHOMA and WEGENER GRANULOMATOSIS.
MSH

An aggressive, progressive, and destructive lesion affecting the nasal cavities, paranasal sinuses, and the palate. The vast majority of cases are malignant lymphoproliferations affecting the midline of the face in patients with nasal type extranodal NK/T-cell lymphoma.
NCI

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afibrinogenémie

A deficiency or absence of fibrinogen (coagulation factor I) in the blood. (Dorland, 27th ed)
MSH

deficiency or absence of fibrinogen (coagulation factor I) in the blood.
CSP

A usually inherited blood coagulation disorder characterized by the lack of fibrinogen in the blood, resulting in bleeding.
NCI

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chromatografie kapalinová

Chromatographic techniques in which the mobile phase is a liquid.
MSH

separation technique in which the moving stage is a liquid and the stationary stage is a solid or liquid on a solid support; components of a mixture in solution are selectively adsorbed.
CSP

A type of chromatography in which separation of a mixture is achieved by passing a sample in a stream of liquid solvent through some form of material that will provide resistance by virtue of chemical interactions between the components of the sample and the material.
NCI

Chromatography, Liquid


HL7V3.0

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metaloporfyriny

Porphyrins which are combined with a metal ion. The metal is bound equally to all four nitrogen atoms of the pyrrole rings. They possess characteristic absorption spectra which can be utilized for identification or quantitative estimation of porphyrins and porphyrin-bound compounds.
MSH

compound of a metal with a porphyrin; metal is bound equally to all four nitrogen atoms of the pyrrole rings.
CSP

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pyrilamin

A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
MSH

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růstová ploténka

The area between the EPIPHYSIS and the DIAPHYSIS within which bone growth occurs.
MSH

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agmatin

Decarboxylated arginine, isolated from several plant and animal sources, e.g., pollen, ergot, herring sperm, octopus muscle.
MSH

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chromozómy lidské, pár 1

A specific pair of human chromosomes in group A (CHROMOSOMES, HUMAN, 1-3) of the human chromosome classification.
MSH

The designation for each member of the largest human autosomal chromosome pair. Chromosome 1 spans about 247 million nucleotide base pairs and represents about 8% of the total DNA in normal diploid cells.
NCI

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methamfetamin

A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.
MSH

sympathomimetic amine closely related chemically to both amphetamine and ephedrine, with actions similar to those of amphetamine; abuse may lead to dependence.
CSP

An amphetamine with central nervous system (CNS) stimulating activity. Methamphetamine acts by both facilitating the release of catecholamines, particularly noradrenaline, dopamine and serotonin, from nerve terminals in the brain and by inhibiting their uptake. This leads to an increase in synaptic concentration of these neurotransmitters and results in increased stimulation of postsynaptic receptors.
NCI

Methamphetamine is a very addictive stimulant drug. It can be smoked, injected, inhaled or taken by mouth. It has many street names, such as speed, meth, and chalk. Methamphetamine hydrochloride, the crystal form inhaled by smoking, is referred to as ice, crystal, glass and tina.

Methamphetamine affects the brain and can create feelings of pleasure, increase energy and elevate mood. Abusers may become addicted quickly, needing higher doses more often. Adverse health effects include irregular heartbeat, increased blood pressure and a variety of psychological problems. Long-term effects may include severe mental disorders, memory loss and severe dental problems.

NIH: National Institute on Drug Abuse


MEDLINEPLUS

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pyruvátkinasa

ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the presence of ATP. It has four isozymes (L, R, M1, and M2). Deficiency of the enzyme results in hemolytic anemia. EC 2.7.1.40.
MSH

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Guernsey

The second largest of the Channel Islands in the English Channel. It covers about 30 square miles and is where the Guernsey breed of cattle originated. The name is Scandinavian, Grani`s island (ey means island). (From Webster`s New Geographical Dictionary, 1988, p474 & Room, Brewer`s Dictionary of Names, 1992, p222)
MSH

A British Crown dependency in the English Channel off the coast of Normandy.
NCI

The island of Guernsey and the other Channel Islands represent the last remnants of the medieval Dukedom of Normandy, which held sway in both France and England. Guernsey is a British crown dependency, but is not part of the UK. (NCI)
NCI

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akinetický mutismus

A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved sensorimotor pathways and vigilance. Bilateral FRONTAL LOBE dysfunction involving the anterior cingulate gyrus and related brain injuries are associated with this condition. This may result in impaired abilities to communicate and initiate motor activities. (From Adams et al., Principles of Neurology, 6th ed, p348; Fortschr Neurol Psychiatr 1995 Feb;63(2):59-67)
MSH

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chylomikrony

A class of lipoproteins that carry dietary CHOLESTEROL and TRIGLYCERIDES from the SMALL INTESTINE to the tissues. Their density (0.93-1.006 g/ml) is the same as that of VERY-LOW-DENSITY LIPOPROTEINS.
MSH

class of lipoproteins that carry dietary cholesterol and triglycerides from the small intestines to the tissues.
CSP

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methoxamin

An alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION.
MSH

adrenergic agent used for its vasopressor effect to support, restore or maintain blood pressure during anesthesia, and in treatment of paroxysmal supraventricular tachycardia.
CSP

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chinin

An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
MSH

quinine ascorbate is listed by USP as a smoking deterrent.
CSP

A quinidine alkaloid isolated from the bark of the cinchona tree. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA replication and transcription via DNA intercalation; and reduction of the excitability of muscle fibers via alteration of calcium distribution. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41253&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41253&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C794″ NCI Thesaurus)
PDQ

A quinidine alkaloid isolated from the bark of the cinchona tree. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA replication and transcription via DNA intercalation; and reduction of the excitability of muscle fibers via alteration of calcium distribution. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)
NCI

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Haemophilus influenzae

species of Haemophilus found on the mucous membranes of humans and a variety of animals; the species is further divided into biotypes I through VIII.
CSP

A species of HAEMOPHILUS found on the mucous membranes of humans and a variety of animals. The species is further divided into biotypes I through VIII.
MSH

A species of facultatively anaerobic or aerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This species is nonmotile, catalase and oxidase positive, porphyrin negative, requires both X and V factors to grow in culture, and may be encapsulated or nonencapsulated. H. influenzae is an opportunistic pathogen causing a wide variety of infections including osteomyelitis, meningitis, conjunctivitis and pneumonia.
NCI

Any bacterial organism that can be assigned to the species Haemophilus influenzae.
NCI

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alkoholy

Alkyl compounds containing a hydroxyl group. They are classified according to relation of the carbon atom: primary alcohols, R-CH2OH; secondary alcohols, R2-CHOH; tertiary alcohols, R3-COH. (From Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

compounds of the type ROH; do not confuse with ETHANOL, the specific alcohol found in intoxicating beverages.
CSP

A class of compounds where a hydroxyl (OH) group is attached to single bonded hydrocarbons. Alcohols are classified according to the position of the carbon atom with the attached hydroxyl group (i.e. primary alcohols are alcohols with the OH group attached to the primary carbon atom, C1). Uses include solvents, astringents, and anti-infective activity.
NCI

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citalopram

A furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.
MSH

selective neuronal serotonin reuptake inhibitor and a clinically effective antidepressant with tolerable side effects; effective in reducing ethanol uptake in alcoholics.
CSP

a kind of antidepressant drug
CHV

A drug used to treat depression. It belongs to the families of drugs called antidepressant agents and selective serotonin reuptake inhibitors (SSRIs).
NCI

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methylortuťné sloučeniny

organic compounds in which mercury is attached to a methyl group.
CSP

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radiační ochrana

measures to reduce exposure to radiation.
CSP

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ruka – deformity

Alterations or deviations from normal shape or size which result in a disfigurement of the hand.
MSH

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alkalóza

A pathological condition that removes acid or adds base to the body fluids.
MSH

pathological condition that removes acid or adds base to the body fluids.
CSP

A disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues.
NCI

An abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues.
NCI

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duchovenstvo

Ordained individuals who perform spiritual and/or religious functions.
NCI

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Mexiko

North American country south of the United States of America.
CSP

A country in Central America, bordering the Caribbean Sea and the Gulf of Mexico, between Belize and the US and bordering the North Pacific Ocean, between Guatemala and the US. (NCI)
NCI

Description:Realm code for use of Mexico


HL7V3.0

A country in Central America, bordering the Caribbean Sea and the Gulf of Mexico, between Belize and the US and bordering the North Pacific Ocean, between Guatemala and the US. (CIA World Factbook 2002)
NCI

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radioimunosorpční test

Radioimmunoassay of proteins using antibody coupled to an immunosorbent.
MSH

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ZEFALEA (ESKL.DOLOR R09,MIGRANA N89)

The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
MSH

pain in the cranial region that may occur as an isolated and benign symptom or as a manifestation of a wide variety of conditions.
CSP

Oh my aching head! Nearly everyone has had a headache. The most common type of headache is a tension headache. Tension headaches are due to tight muscles in your shoulders, neck, scalp and jaw. They are often related to stress, depression or anxiety. You are more likely to get tension headaches if you work too much, don`t get enough sleep, miss meals or use alcohol.

Other common types of headaches include migraines, cluster headaches and sinus headaches. Most people can feel much better by making lifestyle changes, learning ways to relax and taking pain relievers.

Headaches can have many causes, but serious causes of headaches are rare. Sometimes headaches warn of a more serious disorder. Let your health care provider know if you have sudden, severe headaches. Get medical help right away if you have a headache after a blow to your head, or if you have a headache along with a stiff neck, fever, confusion, loss of consciousness or pain in the eye or ear.

NIH: National Institute of Neurological Disorders and Stroke


MEDLINEPLUS

A disorder characterized by a sensation of marked discomfort in various parts of the head, not confined to the area of distribution of any nerve.
NCI

Pain in various parts of the head, not confined to the area of distribution of any nerve.
NCI

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alylisopropylacetamid

An allylic compound that acts as a suicide inactivator of CYTOCHROME P450 by covalently binding to its heme moiety or surrounding protein.
MSH

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Clonorchis sinensis

A species of trematode flukes of the family Opisthorchidae. Many authorities consider this genus belonging to Opisthorchis. It is common in China and other Asiatic countries. Snails and fish are the intermediate hosts.
MSH

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