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mezonefrom

A rare tumor of the female genital tract, most often the ovary, formerly considered to be derived from mesonephric rests. Two varieties are recognized: (1) clear cell carcinoma, so called because of its histologic resemblance to renal cell carcinoma, and now considered to be of muellerian duct derivation and (2) an embryonal tumor (called also ENDODERMAL SINUS TUMOR and yolk sac tumor), occurring chiefly in children. The latter variety may also arise in the testis. (Dorland, 27th ed)
MSH

An adenocarcinoma of the cervix or the vagina arising from mesonephric remnants.
NCI

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Grónsko

An island between the Arctic Ocean and the North Atlantic Ocean, northeast of Canada. (NCI)
NCI

An island between the Arctic Ocean and the North Atlantic Ocean, northeast of Canada. (CIA World Factbook 2002)
NCI

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cytotoxicita imunologická

The phenomenon of target cell destruction by immunologically active effector cells. It may be brought about directly by sensitized T-lymphocytes or by lymphoid or myeloid “killer” cells, or it may be mediated by cytotoxic antibody, cytotoxic factor released by lymphoid cells, or complement.
MSH

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potrat habituální

Three or more consecutive spontaneous abortions.
MSH

spontaneous expulsion of a dead or non-viable fetus in 3 or more consecutive pregnancies at or about the same period of development.
CSP

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apoenzymy

The protein components of enzyme complexes (HOLOENZYMES). An apoenzyme is the holoenzyme minus any cofactors (ENZYME COFACTORS) or prosthetic groups required for the enzymatic function.
MSH

protein components of the enzyme minus any cofactors or prosthetic groups that might be required for the enzyme to be catalytically functional.
CSP

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propidium

Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
MSH

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Squamous metaplasia

A morphologic finding indicating the transformation of glandular or transitional epithelial cells to, usually, mature squamous epithelial cells. Representative examples include squamous metaplasia of bronchial epithelium, cervix, urinary bladder, and prostate gland.
NCI

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guanindeaminasa

An enzyme that catalyzes the deamination of guanine to form xanthine. EC 3.5.4.3.
MSH

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dichlordifenyldichlorethylen

An organochlorine pesticide, it is the ethylene metabolite of DDT.
MSH

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úrazy – prevence

Efforts and designs to reduce the incidence of unexpected undesirable events in various environments and situations.
MSH

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kyselina apurinová

Hydrolysate of DNA in which purine bases have been removed.
MSH

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prostaglandinové endoperoxidy

Precursors in the biosynthesis of prostaglandins and thromboxanes from arachidonic acid. They are physiologically active compounds, having effect on vascular and airway smooth muscles, platelet aggregation, etc.
MSH

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metergolin

A dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for MIGRAINE DISORDERS therapy.
MSH

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Romové

Ethnic group originating in India and entering Europe in the 14th or 15th century.
MSH

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dekomprese explozivní

A sudden loss of pressure in a pressurized cabin, cockpit, or the like, so rapid as to be explosive. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
MSH

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kyselina octová

Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed)
MSH

A synthetic carboxylic acid with antibacterial and antifungal properties. Although its mechanism of action is not fully known, undissociated acetic acid may enhance lipid solubility allowing increased fatty acid accumulation on the cell membrane or in other cell wall structures. Acetic acid, as a weak acid, can inhibit carbohydrate metabolism resulting in subsequent death of the organism.
NCI

An acid found in vinegar. Acetic acid is also used to dissolve substances needed to make some medicines and other products, such as plastics.
NCI

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zdravotní výchova – vzdělávací střediska

Education centers authorized by the Comprehensive Health Manpower Training Act, 1971, for the training of health personnel in areas where health needs are the greatest. May be used for centers other than those established by the United States act.
MSH

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ochranné prostředky

Devices designed to provide personal protection against injury to individuals exposed to hazards in industry, sports, aviation, or daily activities.
MSH

equipment specifically designed to enhance the safety of procedures, work environments, or other equipment; e.g., seat belts, air bags, radiation shields, noise mufflers, air filtering systems, etc.
CSP

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methylcelulosa

Methylester of cellulose. Methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. It is used therapeutically as a bulk laxative.
MSH

methylester of cellulose; used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry and is used therapeutically as a bulk laxative.
CSP

The methyl ether of cellulose with laxative activity. Methylcellulose is not absorbed by the intestines and attracts large amounts of water into the colon, thereby increasing viscosity, producing a softer and bulkier stool and stimulating the constriction of intestinal smooth muscles.
NCI

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Hallervordenův-Spatzův syndrom

A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolescence. Clinical manifestations include progressive MUSCLE SPASTICITY; hyperreflexia; MUSCLE RIGIDITY; DYSTONIA; DYSARTHRIA; and intellectual deterioration which progresses to severe dementia over several years. (From Adams et al., Principles of Neurology, 6th ed, p972; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp972-929)
MSH

A rare autosomal recessive inherited disorder caused by mutations in the PANK2 gene. It is characterized by abnormal accumulation of iron in the basal ganglia. Signs and symptoms include progressive motor disturbances, muscle spasm and rigidity, dysarthria, mental deterioration, and behavioral changes.
NCI

A rare neuroaxonal dystrophy, histologically characterized by axonal spheroids, iron deposition, lewy body (LB)-like intraneuronal inclusions and neurofibrillary tangles.
NCI

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porod – vypuzení plodu a placenty

Delivery of the FETUS and PLACENTA under the care of an obstetrician or a health worker. Obstetric deliveries may involve physical, psychological, medical, or surgical interventions.
MSH

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acetylmuramyl-alanyl-isoglutamin

Peptidoglycan immunoadjuvant originally isolated from bacterial cell wall fragments; also acts as pyrogen and may cause arthritis; stimulates both humoral and cellular immunity.
MSH

A naturally occurring component of bacterial cell walls that has the capacity to activate macrophages.
NCI

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arsenamid

Proposed chemotherapeutic agent against filaria and trichomonas.
MSH

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Proteus vulgaris

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria that occurs in soil, fecal matter, and sewage. It is an opportunistic pathogen and causes cystitis and pyelonephritis.
MSH

Any bacterial organism that can be assigned to the species Proteus vulgaris.
NCI

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methylmočovinové sloučeniny

Urea compounds which are substituted with one or more methyl groups.
MSH

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tvrdost

The mechanical property of material that determines its resistance to force. HARDNESS TESTS measure this property.
MSH

quality of firmness produced by cohesion of the particles composing a substance, observed by its inflexibility or resistance to indentation or distortion.
CSP

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zubní amalgam

An alloy used in restorative dentistry that contains mercury, silver, tin, copper, and possibly zinc.
MSH

alloy of mercury with another metal (usually silver) used by dentists to fill cavities in teeth.
CSP

An amalgam alloy is a device that consists of a metallic substance intended to be mixed with mercury to form filling material for treatment of dental caries.
SPN

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aklarubicin

An anthracycline produced by Streptomyces galilaeus. It has potent antineoplastic activity.
MSH

An oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39131&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39131&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C202″ NCI Thesaurus)
PDQ

An oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin.
NCI

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členovci – vektory

Arthropods, other than insects and arachnids, which transmit infective organisms from one host to another or from an inanimate reservoir to an animate host.
MSH

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pseudogeny

Genes bearing close resemblance to known genes at different loci, but rendered non-functional by additions or deletions in structure that prevent normal transcription or translation. When lacking introns and containing a poly-A segment near the downstream end (as a result of reverse copying from processed nuclear RNA into double-stranded DNA), they are called processed genes.
MSH

inactive but stable components of the genome derived from mutations of ancestral genes; probably account for a significant amount of the so-called “junk DNA” that comprises most of the genome of eukaryotes.
CSP

Nonfunctional DNA sequences that are very similar to the sequences of known genes. Many seem to have arisen as functional gene duplications that subsequently underwent mutation and loss of function. Others are structurally similar to mRNA and seem to have arisen by a reverse transcription event followed by integration into the genome. Some pseudogenes are transcribed and may play a role in regulation of its homologous gene.
NCI

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