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otitis media hnisavá

Inflammation of the middle ear with purulent discharge.
MSH

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zdravotnická zařízení – přesuny

The relocation of health care institutions or units thereof. The concept includes equipment relocation.
MSH

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zesilovače transkripce

cis-acting DNA sequences which can increase transcription of genes; enhancers can usually function in either orientation and at various distances from a promoter.
CSP

Cis-acting DNA sequences which can increase transcription of genes. Enhancers can usually function in either orientation and at various distances from a promoter.
MSH

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kapilární permeabilita

The property of blood capillary ENDOTHELIUM that allows for the selective exchange of substances between the blood and surrounding tissues and through membranous barriers such as the BLOOD-AIR BARRIER; BLOOD-AQUEOUS BARRIER; BLOOD-BRAIN BARRIER; BLOOD-NERVE BARRIER; BLOOD-RETINAL BARRIER; and BLOOD-TESTIS BARRIER. Small lipid-soluble molecules such as carbon dioxide and oxygen move freely by diffusion. Water and water-soluble molecules cannot pass through the endothelial walls and are dependent on microscopic pores. These pores show narrow areas (TIGHT JUNCTIONS) which may limit large molecule movement.
MSH

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receptory serotoninové 5-HT2

A subclass of G-protein coupled SEROTONIN receptors that couple preferentially to the GQ-G11 G-PROTEINS resulting in increased intracellular levels of INOSITOL PHOSPHATES and free CALCIUM.
MSH

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mikroftalmie

congenital or developmental anomaly in which the eyeballs are abnormally small.
CSP

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ovum – transport

Transport of the OVUM or fertilized ovum (ZYGOTE) from the mammalian oviduct (FALLOPIAN TUBES) to the site of EMBRYO IMPLANTATION in the UTERUS.
MSH

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zdravotnické přehledy

a systematic collection of factual data pertaining to health and disease in a human population within a given geographic area.
CSP

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enuréza

Involuntary discharge of URINE after expected age of completed development of urinary control. This can happen during the daytime (DIURNAL ENURESIS) while one is awake or during sleep (NOCTURNAL ENURESIS). Enuresis can be in children or in adults (as persistent primary enuresis and secondary adult-onset enuresis).
MSH

inability to control the flow of urine and involuntary urination.
CSP

An elimination disorder characterized by urinary incontinence, whether involuntary or intentional, which is not due to a medical condition and which occurs at or beyond an age at which continence is expected (usually 5 years).
NCI

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nedoslýchavost z hluku

Hearing loss due to exposure to explosive loud noise or chronic exposure to sound level greater than 85 dB. The hearing loss is often in the frequency range 4000-6000 hertz.
MSH

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životní prostředí – znečištění

introduction into water, air, and soil, any chemicals, toxic substances, wastes, or wastewater in a concentration that makes the medium unfit for its next intended use; also applies to surfaces of objects, buildings, and various household and agricultural use products.
CSP

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sirouhlík

A colorless, flammable, poisonous liquid, CS2. It is used as a solvent, and is a counterirritant and has local anesthetic properties but is not used as such. It is highly toxic with pronounced CNS, hematologic, and dermatologic effects.
MSH

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sexuální delikty

any violation of established legal or moral codes in respect to sexual behavior.
CSP

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vojenské lékařství

The practice of medicine as applied to special circumstances associated with military operations.
MSH

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oxyfenon

A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of ATROPINE. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect.
MSH

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nemoci srdečních chlopní

Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
MSH

condition in which there is a deviation from or interruption of the normal functioning of heart valves.
CSP

Any heart disorder characterized by a defect in valve structure or function.
NCI

Your heart has four valves. Normally, these valves open to let blood flow through or out of your heart, and then shut to keep it from flowing backward. But sometimes they don`t work properly. What can happen?

  • Blood can leak back through the valve in the wrong direction, which is called regurgitation
  • One of the valves, the mitral valve, sometimes has "floppy" flaps and doesn`t close tightly. This is called mitral valve prolapse, and it`s one of the most common heart valve conditions. Sometimes it causes regurgitation
  • When the valve doesn`t open enough, which blocks blood flow, it is called stenosis

Valve problems can be present at birth or caused by infections, heart attacks, or heart disease or damage. Some valve problems are minor and do not need treatment. Others might require medicine, medical procedures or surgery to repair or replace the valve.

NIH: National Heart, Lung, and Blood Institute


MEDLINEPLUS

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karcinoid

A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)
MSH

A slow-growing type of tumor usually found in the gastrointestinal system (most often in the appendix), and sometimes in the lungs or other sites. Carcinoid tumors may spread to the liver or other sites in the body, and they may secrete substances such as serotonin or prostaglandins, causing carcinoid syndrome.
NCI

Carcinoid tumors are rare, slow-growing cancers that usually start in the lining of the digestive tract or in the lungs. Because they grow slowly and don`t produce symptoms in the early stages, the average age of people diagnosed with digestive or lung carcinoids is about 60.

In later stages the tumors sometimes produce hormones that can cause carcinoid syndrome. The syndrome causes flushing of the face and upper chest, diarrhea, and trouble breathing.

Surgery is the main treatment for carcinoid tumors. If they haven`t spread to other parts of the body, surgery can cure the cancer.


MEDLINEPLUS

A usually small, slowly growing tumor usually found in gastrointestinal tract
CHV

A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement.
NCI

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šok hemoragický

Acute hemorrhage or excessive fluid loss resulting in HYPOVOLEMIA.
MSH

hemorrhage decreases the mean systemic filling pressure, therefore decreasing venous return; as a result, the cardiac output falls below normal, and shock ensues.
CSP

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miotika

Agents causing contraction of the pupil of the eye. Some sources use the term miotics only for the parasympathomimetics but any drug used to induce miosis is included here.
MSH

agent that causes the pupil of the eye to contract.
CSP

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bolest

An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
MSH

unpleasant sensation induced by noxious stimuli and generally received by specialized nerve endings.
CSP

Pain is a feeling triggered in the nervous system. Pain may be sharp or dull. It may come and go, or it may be constant. You may feel pain in one area of your body, such as your back, abdomen or chest or you may feel pain all over, such as when your muscles ache from the flu.

Pain can be helpful in diagnosing a problem. Without pain, you might seriously hurt yourself without knowing it, or you might not realize you have a medical problem that needs treatment. Once you take care of the problem, pain usually goes away. However, sometimes pain goes on for weeks, months or even years. This is called chronic pain. Sometimes chronic pain is due to an ongoing cause, such as cancer or arthritis. Sometimes the cause is unknown.

Fortunately, there are many ways to treat pain. Treatment varies depending on the cause of pain. Pain relievers, acupuncture and sometimes surgery are helpful.


MEDLINEPLUS

A disorder characterized by the sensation of marked discomfort, distress or agony.
NCI

The sensation of discomfort, distress, or agony, resulting from the stimulation of specialized nerve endings.
NCI

Causing physical or psychological misery, pain or distress.
NCI

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červi

Commonly known as parasitic worms, this group includes the ACANTHOCEPHALA; NEMATODA; and PLATYHELMINTHS. Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths.
MSH

a type of parasite
CHV

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srdce – minutový objem nízký

A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
MSH

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sigma faktor

A protein which is a subunit of RNA polymerase. It effects initiation of specific RNA chains from DNA.
MSH

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pojivová tkáň – nemoci smíšené

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud`s phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a “speckled” epidermal nuclear staining pattern on direct immunofluorescence.
MSH

An autoimmune overlap syndrome characterized by the presence of symptoms of systemic lupus erythematosus, systemic scleroderma, and polymyositis.
NCI

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pankreas

A nodular organ in the ABDOMEN that contains a mixture of ENDOCRINE GLANDS and EXOCRINE GLANDS. The small endocrine portion consists of the ISLETS OF LANGERHANS secreting a number of hormones into the blood stream. The large exocrine portion (EXOCRINE PANCREAS) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the DUODENUM.
MSH

Lobular organ the parenchyma of which consists of glandular acini which communicate via a duct system with the duodenum. Examples: There is only one pancreas.
UWDA

mixed exocrine and endocrine gland situated transversely across the posterior abdominal wall in the epigastric and hypochondriac regions; endocrine portion is comprised of the islets of Langerhans, and the exocrine portion is a compound acinar gland that secretes digestive enzymes.
CSP

Having to do with the pancreas.
NCI

A glandular organ located in the abdomen. It makes pancreatic juices, which contain enzymes that aid in digestion, and it produces several hormones, including insulin. The pancreas is surrounded by the stomach, intestines, and other organs.
NCI

Lobular organ the parenchyma of which consists of glandular acini which communicate via a duct system with the duodenum. Examples: There is only one pancreas.
FMA

An organ behind the lower part of the stomach that is the shape of a fish and about the size of a hand. It is a compound gland composed of both exocrine and endocrine tissues. The endocrine pancreas makes insulin so that the body can use glucose (sugar) for energy. The exocrine pancreas makes enzymes that help the body digest food. Spread all over the pancreas are areas called the Islets of Langerhans. The cells in these areas each have a special purpose. The alpha cells make glucagon, which raises the level of glucose in the blood; the beta cells make insulin; the delta cells make somatostatin. There are also PP cells and D1 cells, about which little is known. (NCI)
NCI

An organ behind the lower part of the stomach that is the shape of a fish and about the size of a hand. It is a compound gland composed of both exocrine and endocrine tissues. The endocrine pancreas makes insulin so that the body can use glucose (sugar) for energy. The exocrine pancreas makes enzymes that help the body digest food. Spread all over the pancreas are areas called the Islets of Langerhans. The cells in these areas each have a special purpose. The alpha cells make glucagon, which raises the level of glucose in the blood; the beta cells make insulin; the delta cells make somatostatin. There are also PP cells and D1 cells, about which little is known. (from Diabetes Dictionary: http://www.childrenwithdiabetes.com/dictionary)
NCI

Of or pertaining to the pancreas.
NCI

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hematopoéza

The development and formation of various types of BLOOD CELLS. Hematopoiesis can take place in the BONE MARROW (medullary) or outside the bone marrow (HEMATOPOIESIS, EXTRAMEDULLARY).
MSH

formation and development of blood cells.
CSP

The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. [GOC:dgh, ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

A process of blood formation and more specifically formation of blood cells that are all derived from hematopoietic stem cells.
NCI

The formation of new blood cells.
NCI

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Carnivora

have 4 or 5 clawed toes, mobile limbs, carnassal molars, bihorned uterus; primarily eat flesh; can be terrestrial or aquatic.
CSP

An order of MAMMALS, usually flesh eaters with appropriate dentition. Suborders include the terrestrial carnivores Fissipedia, and the aquatic carnivores PINNIPEDIA.
MSH

A diverse taxonomic order of placental mammals that includes bears, dogs, cats, and ferrets. Carnivora are primarily meat eaters, however bears are omnivorous and herbivorous pandas may consume fish and insects.
NCI

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simethikon

A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base.
MSH

A mixture of polydimethylsiloxanes with antifoaming and anti-bloating effects. Simethicone reduces the surface tension of gas bubbles causing them to coalesce into larger bubbles that can be passed more easily by belching or flatulence.
NCI

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Tenericutes

A taxonomic phylum within kingdom Bacteria consisting of the Mollicutes, a class of intracellular parasitic bacteria without a cell wall.
NCI

A phylum of gram-negative bacteria consisting of cells bounded by a plasma membrane. Its organisms differ from other bacteria in that they are devoid of cell walls. This phylum was formerly the class Mollicutes. Mollicutes is now the sole class in the phylum Tenericutes.
MSH

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pantethein

An intermediate in the pathway of coenzyme A formation in mammalian liver and some microorganisms.
MSH

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