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pyridoxalkinasa

An enzyme that catalyzes reversibly the phosphorylation of pyridoxal in the presence of ATP with the formation of pyridoxal 5-phosphate and ADP. Pyridoxine, pyridoxamine and various derivatives can also act as acceptors. EC 2.7.1.35.
MSH

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apendektomie

Surgical removal of the vermiform appendix. (Dorland, 28th ed)
MSH

Surgical removal of the vermiform appendix.
NCI

Surgery to remove the appendix (small finger-shaped pouch at the end of the first part of the large intestine).
NCI

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mikroskopie polarizační

Microscopy using polarized light in which phenomena due to the preferential orientation of optical properties with respect to the vibration plane of the polarized light are made visible and correlated parameters are made measurable.
MSH

Any form of microscopy capable of detecting birefringent objects. Usually performed with a polarizing element below the stage to produce plane polarized light and an analyzer that is set to give total extinction of the background and thus to detect any birefringence.
NCI

Microscopy, Polarized light


HL7V3.0

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ageuzie

Complete or severe loss of the subjective sense of taste, frequently accompanied by OLFACTION DISORDERS.
MSH

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nedoslýchavost z hluku

Hearing loss due to exposure to explosive loud noise or chronic exposure to sound level greater than 85 dB. The hearing loss is often in the frequency range 4000-6000 hertz.
MSH

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smrt náhlá

The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
MSH

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pyruvátkarboxylasa – nedostatek

An autosomal recessive metabolic disorder caused by absent or decreased PYRUVATE CARBOXYLASE activity, the enzyme that regulates gluconeogenesis, lipogenesis, and neurotransmitter synthesis. Clinical manifestations include lactic acidosis, seizures, respiratory distress, marked psychomotor delay, periodic HYPOGLYCEMIA, and hypotonia. The clinical course may be similar to LEIGH DISEASE. (From Am J Hum Genet 1998 Jun;62(6):1312-9)
MSH

A rare autosomal recessive inherited metabolic disorder caused by mutations in the PC gene. It results in the accumulation of lactic acid and other toxic substances in the blood. Signs and symptoms appear early in life and include failure to thrive, mental and growth retardation, motor disturbances, seizures, and lactic acidosis.
NCI

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arachidonát-15-lipoxygenasa

An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.
MSH

Encoded by human ALOX15 Gene, a putative mutator gene regulated by tumor-suppressor TP53, 661-amino acid 74.7 kD cytoplasmic Arachidonate 15-Lipoxygenase (Lipoxygenase Family) acts in leukotriene biosynthesis and is implicated in anti-inflammation, membrane remodeling, and cancer development or metastasis. It converts arachidonic acid to 15s-hydroperoxyeicosatetraenoic acid. (OMIM, Swiss-Prot, and NCI)
NCI

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vojenské lékařství

The practice of medicine as applied to special circumstances associated with military operations.
MSH

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tlak vzduchu

The force per unit area that the air exerts on any surface in contact with it. Primarily used for articles pertaining to air pressure within a closed environment.
MSH

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nemoci srdečních chlopní

Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
MSH

condition in which there is a deviation from or interruption of the normal functioning of heart valves.
CSP

Any heart disorder characterized by a defect in valve structure or function.
NCI

Your heart has four valves. Normally, these valves open to let blood flow through or out of your heart, and then shut to keep it from flowing backward. But sometimes they don`t work properly. What can happen?

  • Blood can leak back through the valve in the wrong direction, which is called regurgitation
  • One of the valves, the mitral valve, sometimes has "floppy" flaps and doesn`t close tightly. This is called mitral valve prolapse, and it`s one of the most common heart valve conditions. Sometimes it causes regurgitation
  • When the valve doesn`t open enough, which blocks blood flow, it is called stenosis

Valve problems can be present at birth or caused by infections, heart attacks, or heart disease or damage. Some valve problems are minor and do not need treatment. Others might require medicine, medical procedures or surgery to repair or replace the valve.

NIH: National Heart, Lung, and Blood Institute


MEDLINEPLUS

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defenzivní medicína

The alterations of modes of medical practice, induced by the threat of liability, for the principal purposes of forestalling lawsuits by patients as well as providing good legal defense in the event that such lawsuits are instituted.
MSH

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chinakrinová hořčice

Nitrogen mustard analog of quinacrine used primarily as a stain in the studies of chromosomes and chromatin. Fluoresces by reaction with nucleic acids in chromosomes.
MSH

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argininsukcinátsynthasa

An enzyme of the urea cycle that catalyzes the formation of argininosuccinic acid from citrulline and aspartic acid in the presence of ATP. Absence or deficiency of this enzyme causes the metabolic disease CITRULLINEMIA in humans. EC 6.3.4.5.
MSH

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miotika

Agents causing contraction of the pupil of the eye. Some sources use the term miotics only for the parasympathomimetics but any drug used to induce miosis is included here.
MSH

agent that causes the pupil of the eye to contract.
CSP

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methanol

A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
MSH

colorless, flammable liquid, CH3OH; an alcohol used in chemical synthesis, in antifreeze, and as a solvent; ingestion of methanol is toxic and may cause blindness.
CSP

Used as a solvent and as an intermediate in chemical synthesis. Component of deicing mixtures and preservatives. Toxic.
NCI

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červi

Commonly known as parasitic worms, this group includes the ACANTHOCEPHALA; NEMATODA; and PLATYHELMINTHS. Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths.
MSH

a type of parasite
CHV

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bludy

A false belief regarding the self or persons or objects outside the self that persists despite the facts, and is not considered tenable by one`s associates.
MSH

false belief regarding the self or persons or objects outside the self that persists despite the facts, and is not considered tenable by one`s associates.
CSP

A disorder characterized by false personal beliefs held contrary to reality, despite contradictory evidence and common sense.
NCI

False personal beliefs held contrary to reality, despite contradictory evidence and common sense.
NCI

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radiační účinky

The effects of ionizing and nonionizing radiation upon living organisms, organs and tissues, and their constituents, and upon physiologic processes. It includes the effect of irradiation on food, drugs, and chemicals.
MSH

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arterioarteriální píštěl

Abnormal communication between two ARTERIES that may result from injury or occur as a congenital abnormality.
MSH

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pojivová tkáň – nemoci smíšené

A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud`s phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a “speckled” epidermal nuclear staining pattern on direct immunofluorescence.
MSH

An autoimmune overlap syndrome characterized by the presence of symptoms of systemic lupus erythematosus, systemic scleroderma, and polymyositis.
NCI

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algináty

Salts of alginic acid that are extracted from marine kelp and used to make dental impressions and as absorbent material for surgical dressings.
MSH

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hematopoéza

The development and formation of various types of BLOOD CELLS. Hematopoiesis can take place in the BONE MARROW (medullary) or outside the bone marrow (HEMATOPOIESIS, EXTRAMEDULLARY).
MSH

formation and development of blood cells.
CSP

The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. [GOC:dgh, ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

A process of blood formation and more specifically formation of blood cells that are all derived from hematopoietic stem cells.
NCI

The formation of new blood cells.
NCI

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zubní kavita – podložka

An inner coating, as of varnish or other protective substance, to cover the dental cavity wall. It is usually a resinous film-forming agent dissolved in a volatile solvent, or a suspension of calcium hydroxide in a solution of a synthetic resin. The lining seals the dentinal tubules and protects the pulp before a restoration is inserted. (Jablonski, Illustrated Dictionary of Dentistry, 1982)
MSH

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rentgendiagnostika zubní

radiographic techniques used in dentistry.
CSP

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aromatické hydroxylasy

A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
MSH

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Tenericutes

A taxonomic phylum within kingdom Bacteria consisting of the Mollicutes, a class of intracellular parasitic bacteria without a cell wall.
NCI

A phylum of gram-negative bacteria consisting of cells bounded by a plasma membrane. Its organisms differ from other bacteria in that they are devoid of cell walls. This phylum was formerly the class Mollicutes. Mollicutes is now the sole class in the phylum Tenericutes.
MSH

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aloxan

pyrimidine ring with carbonyl oxygens at all 4 carbon atoms; an oxidation product of uric acid which, by destroying beta cells in the pancreas, can cause diabetes mellitus; an experimental antineoplastic.
CSP

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hemoglobin A

Normal adult human hemoglobin. The globin moiety consists of two alpha and two beta chains.
MSH

normal adult hemoglobin, composed of 2 alpha and 2 beta chains.
CSP

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zubní čepy

Small cylindrical pieces of metal used to enhance retention.
MSH

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