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anémie dyserytropoetická kongenitální

A familial disorder characterized by ANEMIA with multinuclear ERYTHROBLASTS, karyorrhexis, asynchrony of nuclear and cytoplasmic maturation, and various nuclear abnormalities of bone marrow erythrocyte precursors (ERYTHROID PRECURSOR CELLS). Type II is the most common of the 3 types; it is often referred to as HEMPAS, based on the Hereditary Erythroblast Multinuclearity with Positive Acidified Serum test.
MSH

A rare congenital anemia caused by mutations in the CDAN1 and SEC23B genes.
NCI

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exantém

Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke`s disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.
MSH

A rash is an area of irritated or swollen skin. It might be red and itchy, bumpy, scaly, crusty or blistered. Rashes are a symptom of many different medical conditions. Things that can cause a rash include other diseases, irritating substances, allergies and your genetic makeup.

Contact dermatitis is a common cause of rashes. It causes redness, itching and burning where you have touched an irritant, such as a chemical, or something you are allergic to, like poison ivy.

Some rashes develop immediately. Others form over several days. If you scratch your rash, it might take longer to heal. The treatment for a rash usually depends on its cause. Options include moisturizers, lotions, baths, cortisone creams that relieve swelling, and antihistamines, which relieve itching.


MEDLINEPLUS

Any change in the skin which affects its appearance or texture. A rash may be localized to one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful.
NCI

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symbolismus (psychologie)

A concept that stands for or suggests something else by reason of its relationship, association, convention, or resemblance. The symbolism may be mental or a visible sign or representation. (From Webster, 3d ed)
MSH

concept that stands for or suggests something else by reason of its relationship, association, convention, or resemblance; may be mental or a visible sign or representation.
CSP

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Corynebacterium – infekce

Infections with bacteria of the genus CORYNEBACTERIUM.
MSH

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zvláčňovadla

Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.
MSH

A substance added to plastics or other materials to make or keep them soft or pliable.
NCI

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keratitida

inflammation of the cornea.
CSP

A disorder characterized by inflammation to the cornea of the eye.
NCI

inflammation of the cornea
CHV

Inflammation of the cornea.
NCI

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anestetika disociativní

Intravenous anesthetics that induce a state of sedation, immobility, amnesia, and marked analgesia. Subjects may experience a strong feeling of dissociation from the environment. The condition produced is similar to NEUROLEPTANALGESIA, but is brought about by the administration of a single drug. (From Gilman et al., Goodman and Gilman`s The Pharmacological Basis of Therapeutics, 8th ed)
MSH

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exspirační rezervní objem

The extra volume of air that can be expired with maximum effort beyond the level reached at the end of a normal, quiet expiration. Common abbreviation is ERV.
MSH

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systémová analýza

The analysis of an activity, procedure, method, technique, or business to determine what must be accomplished and how the necessary operations may best be accomplished.
MSH

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Coxiella

A genus of gram-negative, rod-shaped bacteria that is widely distributed in TICKS and various mammals throughout the world. Infection with this genus is particularly prevalent in CATTLE; SHEEP; and GOATS.
MSH

A genus of Gram-negative, acidophilic, rod-shaped, obligate intracellular bacteria in the phylum Proteobacteria.
NCI

Any bacteria that is not assigned to the species level but can be assigned to the Coxiella genus level.
NCI

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pleura – nádory

Neoplasms of the thin serous membrane that envelopes the lungs and lines the thoracic cavity. Pleural neoplasms are exceedingly rare and are usually not diagnosed until they are advanced because in the early stages they produce no symptoms.
MSH

neoplasm of the thin serous membrane that envelopes the lungs and lines the thoracic cavity.
CSP

A benign or malignant neoplasm that involves the serous membrane that lines the lungs and thoracic cavity. Most pleural neoplasms are metastatic. Diffuse malignant mesothelioma is the most common primary malignant neoplasm of the pleura. –2004
NCI

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ketotifen

A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
MSH

A cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.
NCI

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angiotensiny

Oligopeptides which are important in the regulation of blood pressure (VASOCONSTRICTION) and fluid homeostasis via the RENIN-ANGIOTENSIN SYSTEM. These include angiotensins derived naturally from precursor ANGIOTENSINOGEN, and those synthesized.
MSH

angiotensin I, an inactive decapeptide, is cleaved by angiotensin converting enzyme to form the octapeptide angiotensin II, a powerful vasopressor, which is then cleaved to the heptapeptide angiotensin III, an aldosterone stimulant.
CSP

Expressed in liver by human AGT Gene (Serpin Family), secreted 485-aa 53-kDa Angiotensinogen is cleaved by renin (in response to lowered blood pressure) to inactive decapeptide Angiotensin I, which is cleaved by ACE to generate active octapeptide vasopressor Angiotensin II (maintains blood pressure and regulates the volume and mineral balance of body fluids). Angiotensin II is cleaved to Angiotensin III heptapeptide, an aldosterone stimulant.
NCI

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oční infekce

Infection, moderate to severe, caused by bacteria, fungi, or viruses, which occurs either on the external surface of the eye or intraocularly with probable inflammation, visual impairment, or blindness.
MSH

invasion and growth of microorganisms in the eye; may be clinically inapparent or result in local cellular injury; occurs either on the external surface of the eye or intraocularly with probable inflammation, visual impairment, or blindness.
CSP

An infectious process affecting any part of the eye. Causes include viruses and bacteria. Symptoms include itching and discomfort in the eye, watery eyes, eye pain and discharge, and blurring vision. Representative examples include pink eye, blepharitis, and trachoma.
NCI

Your eyes can get infections from bacteria, fungi or viruses. Eye infections can occur in different parts of the eye and can affect just one eye or both. Two common eye infections are

  • Conjunctivitis – also known as pinkeye. Conjunctivitis is often due to an infection. Children frequently get it, and it is very contagious.
  • Stye – a bump on the eyelid that happens when bacteria from your skin get into the hair follicle of an eyelash.

Symptoms of eye infections may include redness, itching, swelling, discharge, pain, or problems with vision. Treatment depends on the cause of the infection and may include compresses, eye drops, creams or antibiotics.


MEDLINEPLUS

A disorder characterized by an infectious process involving the eye.
NCI

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mastek

Finely powdered native hydrous magnesium silicate. It is used as a dusting powder, either alone or with starch or boric acid, for medicinal and toilet preparations. It is also an excipient and filler for pills, tablets, and for dusting tablet molds. (From Merck Index, 11th ed)
MSH

A mineral, usually used in a powdered form. In cancer treatment, sterile talc powder is used to prevent pleural effusions (an abnormal collection of fluid in the space between the lungs and the chest wall). Sterile talc powder is inserted into the space, causing it to close up, so fluid cannot collect there.
NCI

Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42168&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42168&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C854″ NCI Thesaurus)
PDQ

Finely-powdered native hydrous magnesium silicate. When administered into the pleural space, talc initiates an inflammatory reaction, resulting in adhesion of the visceral pleura to the parietal pleura and fibrosis, thereby effectively closing the pleural space and preventing further accumulation of fluid. This agent exhibits no intrinsic antineoplastic activity. (NCI04)
NCI

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syndrom kočičího mňoukání

An infantile syndrome characterized by a cat-like cry, failure to thrive, microcephaly, MENTAL RETARDATION, spastic quadriparesis, micro- and retrognathia, glossoptosis, bilateral epicanthus, hypertelorism, and tiny external genitalia. It is caused by a deletion of the short arm of chromosome 5 (5p-).
MSH

infantile syndrome characterized by a cat-like cry, failure to thrive, microcephaly, mental retardation, spastic quadriparesis, micro- and retrognathia, glossoptosis, bilateral epicanthus, hypertelorism, and tiny external genitalia; caused by a deletion of the short arm of chromosome 5.
CSP

A genetic syndrome resulting from a partial deletion on the short arm of chromosome 5. It is characterized by a cat-like cry in infancy, microcephaly, mental retardation, growth failure, round face, hypertelorism, and cardiac failure.
NCI

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pneumoradiografie

Radiography using air, oxygen, or some other gas as a contrast medium.
MSH

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halančíci

Small oviparous fishes in the family Cyprinodontidae, usually striped or barred black. They are much used in mosquito control.
MSH

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anisoly

A group of compounds that are derivatives of methoxybenzene and contain the general formula R-C7H7O.
MSH

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ústavní řízení a kontrola

Formal voluntary or governmental procedures and standards required of hospitals and health or other facilities to improve operating efficiency, and for the protection of the consumer.
MSH

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daně

Governmental levies on property, inheritance, gifts, etc.
MSH

A charge against a citizen`s person or property or activity for the support of government.
NCI

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zubní korunky

A prosthetic restoration that reproduces the entire surface anatomy of the visible natural crown of a tooth. It may be partial (covering three or more surfaces of a tooth) or complete (covering all surfaces). It is made of gold or other metal, porcelain, or resin.
MSH

A preformed crown is a prefabricated device made of plastic or austenitic alloys or alloys containing 75 percent or greater gold and metals of the platinum group intended to be affixed temporarily to a tooth after removal of, or breakage of, the natural crown (that portion of the tooth that normally protrudes above the gums). It is intended for use as a functional restoration until a permanent crown is constructed. The device also may be intended for use as a functional restoration for a badly decayed deciduous (baby) tooth until the adult tooth erupts.
SPN

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polynukleotidadenylyltransferasa

An enzyme that catalyzes the synthesis of polyadenylic acid from ATP. May be due to the action of RNA polymerase (EC 2.7.7.6) or polynucleotide adenylyltransferase (EC 2.7.7.19). EC 2.7.7.19.
MSH

Nuclear or cytoplasmic human Riboadenylate Transferases (Poly A Polymerase Family) catalyze template-independent post-transcriptional extension of the 3 prime end of an RNA strand by nonspecific and CPSF/AAUAAA-dependent polyadenylation activity during eukaryotic mRNA maturation. The N-terminal region appears required for nonspecific polymerase activity, while the N- and C-termini are required for specific polymerase activity. Specificity may occur through C-terminus interaction with CPSF, regulated by phosphorylation. The poly(A) reaction involves endoribonucleolytic pre-RNA cleavage at the poly(A) site and synthesis of the poly(A) tail. (NCI)
NCI

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vulva – lichen sclerosus

Atrophy and shriveling of the SKIN of the VULVA that is characterized by the whitish LICHEN SCLEROSUS appearance, inflammation, and PRURITUS.
MSH

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anthracene

group of compounds with three aromatic rings joined in linear arrangement.
CSP

Anthracene, also called paranaphthalene or green oil, a solid polycyclic aromatic hydrocarbon (PAH) consisting of three benzene rings derived from coal-tar, is the simplest tricyclic aromatic hydrocarbon. It is on the EPA`s priority pollutant list. It is ubiquitous in the environment as a product of incomplete combustion of fossil fuels. It has been identified in surface and drinking water, ambient air, exhaust emissions, smoke of cigarettes and cigars, and in smoked foods and edible aquatic organisms. It is primarily used as an intermediate in the production of dyes, smoke screens, scintillation counter crystals, and in organic semiconductor research. Although a large body of literature exists on the toxicity of PAHs, data for anthracene are limited. Prolonged exposure causes variety of topical and systemic adverse reactions. Carcinogenicity bioassays with anthracene generally gave negative results.
NCI

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vejcovody – nemoci

Diseases involving the FALLOPIAN TUBES including neoplasms (FALLOPIAN TUBE NEOPLASMS); SALPINGITIS; tubo-ovarian abscess; and blockage.
MSH

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telur

Tellurium. An element that is a member of the chalcogen family. It has the atomic symbol Te, atomic number 52, and atomic weight 127.60. It has been used as a coloring agent and in the manufacture of electrical equipment. Exposure may cause nausea, vomiting, and CNS depression.
MSH

nonmetallic or metalloid element, atomic number 52, symbol Te.
CSP

a kind of chemical element
CHV

An element with atomic symbol Te, atomic number 52, and atomic weight 127.6.
NCI

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kuprizon

Copper chelator that inhibits monoamine oxidase and causes liver and brain damage.
MSH

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polyethyleny

Synthetic thermoplastics that are tough, flexible, inert, and resistant to chemicals and electrical current. They are often used as biocompatible materials for prostheses and implants.
MSH

polymerized ethylene; a synthetic plastic material, forms of which have been used in reparative surgery.
CSP

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zvířata laboratorní – věda

The science and technology dealing with the procurement, breeding, care, health, and selection of animals used in biomedical research and testing.
MSH

The science and technology concerned with the procurement, selection, health and welfare of animals used in research and testing.
NCI

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