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kolektomie

Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)
MSH

An operation to remove all or part of the colon. When only part of the colon is removed, it is called a partial colectomy. In an open colectomy, one long incision is made in the wall of the abdomen and doctors can see the colon directly. In a laparoscopic-assisted colectomy, several small incisions are made and a thin, lighted tube attached to a video camera is inserted through one opening to guide the surgery. Surgical instruments are inserted through the other openings to perform the surgery.
NCI

a surgery to remove all or part of the large bowel
CHV

Surgical removal of part or all of the colon.
NCI

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leukémie myelomonocytární akutní

A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of monocytic origin.
MSH

An acute leukemia characterized by the proliferation of both neutrophil and monocyte precursors. Patients typically present with anemia, thrombocytopenia, fever and fatigue. This type of leukemia frequently responds to aggressive therapy. (WHO, 2001) — 2003
NCI

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průtokoměry

Devices used to measure the flow of fluids (see RHEOLOGY) or the AIR to measure RESPIRATION.
MSH

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stomatitida

INFLAMMATION of the soft tissues of the MOUTH, such as MUCOSA; PALATE; GINGIVA; and LIP.
MSH

inflammation of the oral mucosa due to local or systemic factors.
CSP

Inflammation or irritation of the mucous membranes in the mouth.
NCI

A disorder characterized by inflammation of the oral mucosal.
NCI

inflammation of the mucous tissue of the mouth
CHV

Inflammation of the oral mucosa due to local or systemic factors.
NCI

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feofytiny

Chlorophylls from which the magnesium has been removed by treatment with weak acid.
MSH

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kolobom

Congenital anomaly in which some of the structures of the eye are absent due to incomplete fusion of the fetal intraocular fissure during gestation.
MSH

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leukotrien C4

The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
MSH

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floxuridin

An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
MSH

antineoplastic antimetabolite; has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
CSP

A drug used in the treatment of cancer. It is a type of antimetabolite.
NCI

A fluorinated pyrimidine monophosphate analogue of 5-fluoro-2`-deoxyuridine-5`-phosphate (FUDR-MP) with antineoplastic activity. As an antimetabolite, floxuridine inhibits thymidylate synthetase, resulting in disruption of DNA synthesis and cytotoxicity. This agent is also metabolized to fluorouracil and other metabolites that can be incorporated into RNA and inhibit the utilization of preformed uracil in RNA synthesis. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39242&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39242&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C504″ NCI Thesaurus)
PDQ

A fluorinated pyrimidine monophosphate analogue of 5-fluoro-2`-deoxyuridine-5`-phosphate (FUDR-MP) with antineoplastic activity. As an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity. This agent is also metabolized to fluorouracil and other metabolites that can be incorporated into RNA and inhibit the utilization of preformed uracil in RNA synthesis. (NCI04)
NCI

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streptozocin

An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
MSH

2-deoxy-2-(3-methyl-3-nitrosoureido) -D-glucopyranose; USP antineoplastic antibiotic; at high doses it destroys pancreatic beta cells and can be used to create experimental animal models of diabetes mellitus.
CSP

An anticancer drug that belongs to the family of drugs called alkylating agents.
NCI

A methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand DNA cross-links and inhibiting DNA synthesis. Due to its glucose moiety, this agent is readily taken up by pancreatic beta cells, inducing diabetes mellitus at high concentrations. Unlike other nitrosoureas, streptozocin causes little myelosuppression. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42831&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42831&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C845″ NCI Thesaurus)
PDQ

A methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand DNA cross-links and inhibiting DNA synthesis. Due to its glucose moiety, this agent is readily taken up by pancreatic beta cells, inducing diabetes mellitus at high concentrations. Unlike other nitrosoureas, streptozocin causes little myelosuppression. (NCI04)
NCI

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forboly

The parent alcohol of the tumor promoting compounds from CROTON OIL (Croton tiglium).
MSH

phorbol esters such as PMA and TPA are widely used as experimental tumor promotors; they act by directly stimulating protein kinase C, bypassing its normal calcium-based integration with other cellular processes.
CSP

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kombinovaná terapie

The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.
MSH

simultaneous or sequential treatment of a disease or condition using more than one means, such as by any combination of chemotherapy, radiation therapy, immunotherapy, or surgery.
CSP

Therapy that combines more than one method of treatment.
NCI

Use of two or more simultaneous or consecutive treatment modalities; e.g., surgery + radiation, or radiation + immunotherapy. Does not refer to use of two or more chemotherapeutic agents.
NCI

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licence nemocniční

The granting of a license to a hospital.
MSH

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folikulární cysta

Cyst due to the occlusion of the duct of a follicle or small gland.
MSH

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studenti farmacie

Individuals enrolled in a school of pharmacy or a formal educational program leading to a degree in pharmacy.
MSH

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fosfolipasy A1

A phospholipase that hydrolyzes the acyl group attached to the 1-position of PHOSPHOGLYCERIDES.
MSH

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společenskoinstitucionální vztahy

The interactions between members of a community and representatives of the institutions within that community.
MSH

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Limulus test

Sensitive method for detection of bacterial endotoxins and endotoxin-like substances that depends on the in vitro gelation of Limulus amebocyte lysate (LAL), prepared from the circulating blood (amebocytes) of the horseshoe crab, by the endotoxin or related compound. Used for detection of endotoxin in body fluids and parenteral pharmaceuticals.
MSH

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kosti nohy

The TARSAL BONES; METATARSAL BONES; and PHALANGES OF TOES. The tarsal bones consists of seven bones: CALCANEUS; TALUS; cuboid; navicular; internal; middle; and external cuneiform bones. The five metatarsal bones are numbered one through five, running medial to lateral. There are 14 phalanges in each foot, the great toe has two while the other toes have three each.
MSH

The tarsus, metatarsus, and phalanges. (MeSH)
NCI

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drogy – odhalování abúzu

Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. Urine screening is the usual method of detection.
MSH

A laboratory test of biological material such as blood, urine, hair, saliva or sweat, used to detect the presence of a drug or its metabolites with in the body.
NCI

procedures to detect the presence of drugs or their side products in blood, urine, breath, or other biological samples; do not confuse with DRUG SCREENING/EVALUATION.
CSP

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fosfoserin

The phosphoric acid ester of serine.
MSH

serine, threonine, and tyrosine are the residues which are phosphorylated in proteins.
CSP

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komplement C9

A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
MSH

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lipofuscin

A naturally occurring lipid pigment with histochemical characteristics similar to ceroid. It accumulates in various normal tissues and apparently increases in quantity with age.
MSH

naturally occurring lipid pigment with histochemical characteristics similar to ceroid; it accumulates in various normal tissues and apparently increases in quantity with age.
CSP

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formamide

group of amides with the general formula of R-CONH2.
CSP

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sebevražda

The act of killing oneself.
MSH

act or an instance of intentionally killing oneself.
CSP

Suicide is the eleventh most common cause of death in the United States. People may consider suicide when they are hopeless and can`t see any other solution to their problems. Often it`s related to serious depression, alcohol or substance abuse, or a major stressful event.

People who have the highest risk of suicide are white men. But women and teens report more suicide attempts. If someone talks about suicide, you should take it seriously. Urge them to get help from their doctor or the emergency room, or call the National Suicide Prevention Lifeline at 1-800-273-TALK (8255). It is available 24/7.

Therapy and medicines can help most people who have suicidal thoughts. Treating mental illnesses and substance abuse can reduce the risk of suicide.

NIH: National Institute of Mental Health


MEDLINEPLUS

The act of taking one`s own life on purpose.
NCI

The act of ending one`s own life.
NCI

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tělesná výchova

Instructional programs in the care and development of the body, often in schools. The concept does not include prescribed exercises, which is EXERCISE THERAPY.
MSH

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počítače – základní jednotka

Large computers in both size and capacity.
MSH

a large, fast computer whose capacity will support multiple, simultaneous users and applications; it is the largest type of computer.
CSP

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Literacy

The ability to read and write.
NCI

the ability to read and write
CHV

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fraktury otevřené

Fractures in which there is an external wound communicating with the break of the bone.
MSH

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sulfhydrylová reagencia

Chemical agents that react with SH groups. This is a chemically diverse group that is used for a variety of purposes. Among these are enzyme inhibition, enzyme reactivation or protection, and labelling.
MSH

compounds which interact with disulfide bonds and sulfhydryl groups in proteins to either favor or inhibit the formation of disulfide crosslinks; usually means a reducing agent which inhibits disulfide formation.
CSP

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fytol

A chemical substance that comes from plants and is used to make vitamins E and K. Phytol is also found in soaps, beauty care products, and household products.
NCI

An acyclic diterpene alcohol and a constituent of chlorophyll. Phytol is commonly used as a precursor for the manufacture of synthetic forms of vitamin E and vitamin K1. Furthermore, phytol also was shown to modulate transcription in cells via transcription factors PPAR-alpha and retinoid X receptor (RXR).
NCI

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