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prostaglandiny F

(9 alpha,11 alpha,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid (PGF(1 alpha)); (5Z,9 alpha,11,alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid (PGF(2 alpha)); (5Z,9 alpha,11 alpha,13E,15S,17Z)-9,11,15-trihydroxyprosta-5,13,17-trien-1-oic acid (PGF(3 alpha)). A family of prostaglandins that includes three of the six naturally occurring prostaglandins. All naturally occurring PGF have an alpha configuration at the 9-carbon position. They stimulate uterine and bronchial smooth muscle and are often used as oxytocics.
MSH

stable prostaglandin formed from PGH2 or PGE2; stimulates the contraction of uterine and bronchial smooth muscle and produces vasoconstriction in some vessels.
CSP

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antifungální látky

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
MSH

substances that are destructive to fungi, suppress their reproduction or growth, or are effective against fungal infection.
CSP

a drug that kills fungus
CHV

Drugs that treat infections caused by fungi.
NCI

Substances that treat systemic or topical infections caused by fungi. Antifungal agents kill or inhibit the growth of fungi, by various mechanisms. Mechanisms include inhibition of fungal mitosis, impairing synthesis or binding to ergosterol, incorporation into RNA or DNA synthesis inhibition.
NCI

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membránové proteiny

Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.
MSH

proteins which are found in membranes including cellular and intracellular membranes; consist of two types, peripheral and integral proteins; includes most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors; note that individual membrane proteins have not been exhaustively treed under this term.
CSP

Proteins that are physically associated with the membrane. This class of proteins resides in cellular or intracellular membranes. The physical association of each protein is divided into two classes: integral and peripheral.
NCI

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glycylglycin

The simplest of all peptides. It functions as a gamma-glutamyl acceptor.
MSH

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acetoxyacetylaminofluoren

An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.
MSH

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cystamin

A radiation-protective agent that interferes with sulfhydryl enzymes. It may also protect against carbon tetrachloride liver damage.
MSH

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proteinkinasa C

An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.
MSH

nonEC.
CSP

An enzyme found throughout the body`s tissues and organs. Several forms of PKC are involved in many cellular functions. PKC is being studied in the treatment of cancer.
NCI

A family of serine/threonine protein kinases that have a structurally conserved catalytic subunit and a regulatory subunit that are connected by a hinge domain.
NCI

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antimalarika

Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)
MSH

agent used in the treatment or prevention of malaria.
CSP

Agents used to treat malaria, and are usually classified based on action against plasmodia at different stages in their life cycle in the human.
NCI

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menopauza

The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.
MSH

cessation of menstruation in the human female, usually occurring around the age of 50.
CSP

The time of life when a woman`s ovaries stop producing hormones and menstrual periods stop. Natural menopause usually occurs around age 50. A woman is said to be in menopause when she hasn`t had a period for 12 months in a row. Symptoms of menopause include hot flashes, mood swings, night sweats, vaginal dryness, trouble concentrating, and infertility.
NCI

Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50. [GOC:curators, PMID:18495681]
GO

Menopause is the time in a woman`s life when her period stops. It usually occurs naturally, most often after age 45. Menopause happens because the woman`s ovary stops producing the hormones estrogen and progesterone.

A woman has reached menopause when she has not had a period for one year. Changes and symptoms can start several years earlier. They include

  • A change in periods – shorter or longer, lighter or heavier, with more or less time in between
  • Hot flashes and/or night sweats
  • Trouble sleeping
  • Vaginal dryness
  • Mood swings
  • Trouble focusing
  • Less hair on head, more on face

Some symptoms require treatment. Talk to your doctor about how to best manage menopause. Make sure the doctor knows your medical history and your family medical history. This includes whether you are at risk for heart disease, osteoporosis, or breast cancer.

National Women`s Health Information Center


MEDLINEPLUS

A disorder characterized by the permanent cessation of menses, usually defined by 12 consecutive months of amenorrhea in a woman over 45 years of age.
NCI

The permanent cessation of menses, usually defined by 6 to 12 months of amenorrhea in a woman over 45 years of age.
NCI

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gonády

The gamete-producing glands, OVARY or TESTIS.
MSH

gamete-producing glands.
CSP

General anatomical term which refers to ovary or testis.
FMA

The part of the reproductive system that produces and releases eggs (ovaries) or sperm (testicles/testes).
NCI

A reproductive system organ that produces and releases either sperm (testis) or eggs (ovary).
NCI

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Achondrogeneze

A rare group of disorders characterized by defective development of bones and cartilage.
NCI

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cytidindeaminasa

An enzyme that catalyzes the deamination of cytidine, forming uridine. EC 3.5.4.5.
MSH

Cytidine deaminase (146 aa, ~16 kDa) is encoded by the human CDA gene. This protein is involved in the deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. (Entrez Gene)
NCI

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Prototheca

A genus of achlorophyllic algae in the family Chlorellaceae, and closely related to CHLORELLA. It is found in decayed matter; WATER; SEWAGE; and SOIL; and produces cutaneous and disseminated infections in various VERTEBRATES including humans.
MSH

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treponematocidní látky

Agents used to treat infections with bacteria of the genus TREPONEMA. This includes SYPHILIS & YAWS.
MSH

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rtuť – isotopy

Stable mercury atoms that have the same atomic number as the element mercury, but differ in atomic weight. Hg-196, 198-201, and 204 are stable mercury isotopes.
MSH

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granulocyty

Leukocytes with abundant granules in the cytoplasm. They are divided into three groups according to the staining properties of the granules: neutrophilic, eosinophilic, and basophilic. Mature granulocytes are the NEUTROPHILS; EOSINOPHILS; and BASOPHILS.
MSH

leukocytes with abundant neutrophilic, eosinophilic or basophilic granules in the cytoplasm; mature granulocytes are the neutrophils, eosinophils, and basophils.
CSP

A type of immune cell that has granules (small particles) with enzymes that are released during infections, allergic reactions, and asthma. Neutrophils, eosinophils, and basophils are granulocytes. A granulocyte is a type of white blood cell.
NCI

A leucocyte with conspicuous cytoplasmic granules. In humans the granulocytes are also classified as polymorphonuclear leucocytes and are subdivided according to the staining properties of the granules into eosinophils, basophils and neutrophils. (On-line Medical Dictionary)
NCI

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AIDS

An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
MSH

one or more indicator diseases, depending on laboratory evidence of HIV infection (CDC); late phase of HIV infection characterized by marked suppression of immune function resulting in opportunistic infections, neoplasms, and other systemic symptoms (NIAID).
CSP

A disease caused by human immunodeficiency virus (HIV). People with acquired immunodeficiency syndrome are at an increased risk for developing certain cancers and for infections that usually occur only in individuals with a weak immune system.
NCI

A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin`s lymphoma and Kaposi`s sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood.
NCI

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biologie buňky

for thorough searching also see CYTOLOGY.
CSP

The study of the structure, behavior, growth, reproduction, and pathology of cells; and the function and chemistry of cellular components.
MSH

The study of cells using a microscope.
NCI

The light microscopic study of normal and abnormal cells in fine needle aspirates (FNAs), body cavity fluids, and smears.
NCI

The study of the internal workings of cells at the microscopic and molecular level. (On-line Medical Dictionary)
NCI

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Pseudomonas pseudomallei

A species of gram-negative, aerobic bacteria that causes MELIOIDOSIS. It has been isolated from soil and water in tropical regions, particularly Southeast Asia.
MSH

Any bacterial organism that can be assigned to the species Burkholderia pseudomallei.
NCI

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aortální chlopeň – stenóza

A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
MSH

constriction in the opening of the aortic valve or of the supravalvular or subvalvular regions.
CSP

Narrowing of the orifice of the aortic valve or of the supravalvular or subvalvular regions.
NCI

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metabolismus

The chemical reactions that occur within the cells, tissues, or an organism. These processes include both the biosynthesis (ANABOLISM) and the breakdown (CATABOLISM) of organic materials utilized by the living organism.
MSH

sum of chemical changes that occur within the tissues of an organism consisting of anabolism (biosynthesis) and catabolism; the buildup and breakdown of molecules for utilization by the organism.
CSP

The chemical changes that take place in a cell or an organism. These changes make energy and the materials cells and organisms need to grow, reproduce, and stay healthy. Metabolism also helps get rid of toxic substances.
NCI

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. [GOC:go_curators, ISBN:0198547684]
GO

All the reactions in an organism concerned with storing and generating metabolic energy and with the biosynthesis of low-molecular weight compounds, energy-storage compounds, and basic materials needed for important life processes. It does not include nucleic acid and protein synthesis.
NCI

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skupinové procesy

The procedures through which a group approaches, attacks, and solves a common problem.
MSH

procedures by which a group of individuals approach and solve their common objectives.
CSP

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aktinomykóza cervikofaciální

A form of ACTINOMYCOSIS characterized by slow-growing inflammatory lesions of the lymph nodes that drain the mouth (lumpy jaw), reddening of the overlying skin, and intraperitoneal abscesses.
MSH

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tanec

Rhythmic and patterned body movements which are usually performed to music.
MSH

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psychologické testy

standardized tests designed to measure abilities, as in intelligence, aptitude, and achievement tests, or to evaluate personality traits.
CSP

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apendektomie

Surgical removal of the vermiform appendix. (Dorland, 28th ed)
MSH

Surgical removal of the vermiform appendix.
NCI

Surgery to remove the appendix (small finger-shaped pouch at the end of the first part of the large intestine).
NCI

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methacholinové sloučeniny

A group of compounds that are derivatives of beta-methylacetylcholine (methacholine).
MSH

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guanosintrifosfát

Guanosine 5`-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety.
MSH

guanosine 5`-(tetrahydrogen triphosphate); a guanine nucleotide containing three phosphate groups esterified to the sugar moiety.
CSP

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adenin

A purine base and a fundamental unit of ADENINE NUCLEOTIDES.
MSH

6-aminopurine; one of the 5 major bases (with guanine, thymine, cytosine, and uracil) found in nucleic acids.
CSP

A chemical compound that is used to make one of the building blocks of DNA and RNA. It is also a part of many substances in the body that give energy to cells. Adenine is a type of purine.
NCI

A purine base and a fundamental unit of adenine nucleotides. (MeSH)
NCI

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smrt náhlá

The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
MSH

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