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argininsukcinátsynthasa

An enzyme of the urea cycle that catalyzes the formation of argininosuccinic acid from citrulline and aspartic acid in the presence of ATP. Absence or deficiency of this enzyme causes the metabolic disease CITRULLINEMIA in humans. EC 6.3.4.5.
MSH

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estetika

The branch of philosophy dealing with the nature of the beautiful. It includes beauty, esthetic experience, esthetic judgment, esthetic aspects of medicine, etc.
MSH

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proteinkinasa C

An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters.
MSH

nonEC.
CSP

An enzyme found throughout the body`s tissues and organs. Several forms of PKC are involved in many cellular functions. PKC is being studied in the treatment of cancer.
NCI

A family of serine/threonine protein kinases that have a structurally conserved catalytic subunit and a regulatory subunit that are connected by a hinge domain.
NCI

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bludy

A false belief regarding the self or persons or objects outside the self that persists despite the facts, and is not considered tenable by one`s associates.
MSH

false belief regarding the self or persons or objects outside the self that persists despite the facts, and is not considered tenable by one`s associates.
CSP

A disorder characterized by false personal beliefs held contrary to reality, despite contradictory evidence and common sense.
NCI

False personal beliefs held contrary to reality, despite contradictory evidence and common sense.
NCI

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nádor z ostrůvkových buněk

A benign tumor of the pancreatic ISLET CELLS. Usually it involves the INSULIN-producing PANCREATIC BETA CELLS, as in INSULINOMA, resulting in HYPERINSULINISM.
MSH

A benign endocrine neoplasm arising from the pancreas. It is separated from the normal pancreatic tissues by a thin collagenous capsule. It may secrete a hormone (e.g. insulin, gastrin) or it may be non-functional.
NCI

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Achondrogeneze

A rare group of disorders characterized by defective development of bones and cartilage.
NCI

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arterioarteriální píštěl

Abnormal communication between two ARTERIES that may result from injury or occur as a congenital abnormality.
MSH

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ethanolaminfosfotransferasa

An enzyme that catalyzes reversibly the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to yield phosphatidylethanolamine (cephalin) and CMP. The enzyme is found in the endoplasmic reticulum. EC 2.7.8.1.
MSH

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Prototheca

A genus of achlorophyllic algae in the family Chlorellaceae, and closely related to CHLORELLA. It is found in decayed matter; WATER; SEWAGE; and SOIL; and produces cutaneous and disseminated infections in various VERTEBRATES including humans.
MSH

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zubní kavita – podložka

An inner coating, as of varnish or other protective substance, to cover the dental cavity wall. It is usually a resinous film-forming agent dissolved in a volatile solvent, or a suspension of calcium hydroxide in a solution of a synthetic resin. The lining seals the dentinal tubules and protects the pulp before a restoration is inserted. (Jablonski, Illustrated Dictionary of Dentistry, 1982)
MSH

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isosorbiddinitrát

A vasodilator used in the treatment of ANGINA PECTORIS. Its actions are similar to NITROGLYCERIN but with a slower onset of action.
MSH

The dinitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide dinitrate relaxes vascular smooth muscle by formation of the free radical nitric oxide (NO), which is identical to the endothelium-derived relaxing factor (EDRF). NO activates guanylyl cyclase, thereby increasing the synthesis of cGMP within smooth muscle, resulting in dephosphorylation of light chain myosin and relaxation of peripheral arteries and veins. In addition, isosorbide dinitrate relaxes coronary arteries, thereby increasing the blood circulation through the ischemic area. (NCI05)
NCI

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AIDS

An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.
MSH

one or more indicator diseases, depending on laboratory evidence of HIV infection (CDC); late phase of HIV infection characterized by marked suppression of immune function resulting in opportunistic infections, neoplasms, and other systemic symptoms (NIAID).
CSP

A disease caused by human immunodeficiency virus (HIV). People with acquired immunodeficiency syndrome are at an increased risk for developing certain cancers and for infections that usually occur only in individuals with a weak immune system.
NCI

A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin`s lymphoma and Kaposi`s sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood.
NCI

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aromatické hydroxylasy

A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
MSH

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etologie

The discipline pertaining to the study of animal behavior.
MSH

discipline pertaining to the study of animal behavior.
CSP

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Pseudomonas pseudomallei

A species of gram-negative, aerobic bacteria that causes MELIOIDOSIS. It has been isolated from soil and water in tropical regions, particularly Southeast Asia.
MSH

Any bacterial organism that can be assigned to the species Burkholderia pseudomallei.
NCI

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zubní čepy

Small cylindrical pieces of metal used to enhance retention.
MSH

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virus JC

A species of POLYOMAVIRUS, originally isolated from the brain of a patient with progressive multifocal leukoencephalopathy. The patient`s initials J.C. gave the virus its name. Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus.
MSH

isolated from brain of patient with progressive multifocal leucoencephalopathy; antibodies found in man, suggesting it is a common infection; experimentally virus is highly oncogenic in new-born hamsters.
CSP

One of two polyomaviruses found in humans. JC virus can infect the respiratory system, kidneys, or brain, sometimes causing the fatal progressive multifocal leukoencephalopathy in the latter case. It is very widespread with approximately 80 percent of the adult population in the United States having antibodies to and JC. (from WordIQ.com)
NCI

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aktinomykóza cervikofaciální

A form of ACTINOMYCOSIS characterized by slow-growing inflammatory lesions of the lymph nodes that drain the mouth (lumpy jaw), reddening of the overlying skin, and intraperitoneal abscesses.
MSH

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aspartátaminotransferasy

Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L-glutamate. EC 2.6.1.1.
MSH

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etiocholanolon

The 5-beta-reduced isomer of ANDROSTERONE. Etiocholanolone is a major metabolite of TESTOSTERONE and ANDROSTENEDIONE in many mammalian species including humans. It is excreted in the URINE.
MSH

A 17-ketosteroid which excreted in the urine as a metabolite of steroid hormones. The most common form of etiocholanolone present in the urine is the sulfate salt. This agent, also known as 5-isoandrosterone, may be used to evaluate adrenal cortex function, bone marrow performance and, in neoplastic disease, for immunostimulation. (NCI04)
NCI

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psychologické testy

standardized tests designed to measure abilities, as in intelligence, aptitude, and achievement tests, or to evaluate personality traits.
CSP

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dentin – rozpustnost

The susceptibility of the DENTIN to dissolution.
MSH

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juxtaglomerulární aparát

A complex of cells consisting of juxtaglomerular cells, extraglomerular mesangium lacis cells, the macula densa of the distal convoluted tubule, and granular epithelial peripolar cells. Juxtaglomerular cells are modified SMOOTH MUSCLE CELLS found in the walls of afferent glomerular arterioles and sometimes the efferent arterioles. Extraglomerular mesangium lacis cells are located in the angle between the afferent and efferent glomerular arterioles. Granular epithelial peripolar cells are located at the angle of reflection of the parietal to visceral angle of the renal corpuscle.
MSH

specialized cells containing secretory granules, located in the tunica media of the afferent glomerular arterioles; major structural component responsible for the release of renin; play a major role in renal autoregulation.
CSP

Cellular population adjacent to the renal corpuscle, composed of the macula densa, the juxtaglomerular cells, and the extraglomerular mesangial cells. It regulates the blood pressure by activating the renin-angiotensin-aldosterone system.
NCI

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adenin

A purine base and a fundamental unit of ADENINE NUCLEOTIDES.
MSH

6-aminopurine; one of the 5 major bases (with guanine, thymine, cytosine, and uracil) found in nucleic acids.
CSP

A chemical compound that is used to make one of the building blocks of DNA and RNA. It is also a part of many substances in the body that give energy to cells. Adenine is a type of purine.
NCI

A purine base and a fundamental unit of adenine nucleotides. (MeSH)
NCI

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astma z námahy

Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).
MSH

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excipienty

Usually inert substances added to a prescription in order to provide suitable consistency to the dosage form. These include binders, matrix, base or diluent in pills, tablets, creams, salves, etc.
MSH

Any intentionally added component of a finished pharmaceutical product other than the claimed therapeutic or diagnostic ingredient(s). The excipients are added to facilitate administration or manufacture, improve product delivery, promote the consistent release and bioavailability of the drug, enhance stability, assist in product identification, or enhance other product characteristics. Pharmaceutical excipients do not affect therapeutic effects of the preparation or suitable tests or assays. The term does not apply to macromolecular compounds like albumin, or compounds like amino acids and sugars that are used in biological products, nor does it apply to process or product-related impurities (e.g. degradation products, residual solvents), or extraneous contaminants.
NCI

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psychoterapie

A generic term for the treatment of mental illness or emotional disturbances primarily by verbal or nonverbal communication.
MSH

treatment of emotional, behavioral, personality, and psychiatric disorders based primarily upon verbal or nonverbal communication and interventions with the patient.
CSP

Treatment of mental, emotional, personality, and behavioral disorders using methods such as discussion, listening, and counseling.
NCI

A method of treating disease, esp. psychic disorders, by mental rather than pharmacological means (e.g., suggestion, re-education, hypnotism, and psychoanalysis). (Taber`s)
NCI

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kyselina deoxycholová

A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
MSH

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keratokonjunktivitida

simultaneous inflammation of the cornea and conjunctiva.
CSP

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ATPasa Ca(2+) Mg(2+)

An enzyme that catalyzes the hydrolysis of ATP and is activated by millimolar concentrations of either Ca(2+) or Mg(2+). Unlike CA(2+)-TRANSPORTING ATPASE it does not require the second divalent cation for its activity, and is not sensitive to orthovanadate. (Prog Biophys Mol Biol 1988;52(1):1). A subgroup of EC 3.6.1.3.
MSH

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