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ricin

A protein phytotoxin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells, is proteolytic, and causes lethal inflammation and hemorrhage if taken internally.
MSH

proteinaceous phytotoxin from the castor oil plant, Ricinus communis; A chain has glycosidase activity which cleaves 28S rRNA, halting protein synthesis; extreme cytotoxicity makes ricin an attractive candidate for artificial fusion with binding proteins to create cell-type-specific toxins.
CSP

A highly toxic protein phytotoxin lectin and hemagglutin from the seeds of Ricinus communis, the castor oil plant. It agglutinates cells, is proteolytic, and causes lethal inflammation and hemorrhage if taken internally. It has N-glycosidase activity that cleaves 28S rRNA, halting protein synthesis; extreme cytotoxicity makes ricin an attractive candidate for artificial fusion with binding proteins to create cell-type-specific toxins.
NCI

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nos – nádory

Tumors or cancer of the NOSE.
MSH

new abnormal nasal tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease; includes neoplasm of the external structure, through the nasal cavity, sinuses and up to the nasopharynx.
CSP

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N-formylmethionin-leucyl-fenylalanin

N-Formylmethionyl-leucyl-phenylalanine. A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.
MSH

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deprese reaktivní

Depression precipitated by events in a person`s life.
NCI

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holothurin

A highly toxic saponin occurring in HOLOTHUROIDEA. This marine toxin is an anionic surfactant, hemolyzing ERYTHROCYTES.
MSH

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poslech

Act of listening for sounds within the body.
MSH

Listening with a device, such as a stethoscope, to anatomical locations that produce audible sounds like the heart, lungs and abdomen.
NCI

the act of listening for sounds made by internal organs, as the heart and lungs
CHV

Listening with a device, such as a stethoscope, to anatomical locations that produce audible sounds like the heart, lungs and abdomen.
NCI

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rizikové řízení

The process of minimizing risk to an organization by developing systems to identify and analyze potential hazards to prevent accidents, injuries, and other adverse occurrences, and by attempting to handle events and incidents which do occur in such a manner that their effect and cost are minimized. Effective risk management has its greatest benefits in application to insurance in order to avert or minimize financial liability. (From Slee & Slee: Health care terms, 2d ed)
MSH

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jadérko – oblast organizátoru

The chromosome region which is active in nucleolus formation and which functions in the synthesis of ribosomal RNA.
MSH

A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed. [PMID:14504406]
GO

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naled

An organophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
MSH

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desmozómy

A type of junction that attaches one cell to its neighbor. One of a number of differentiated regions which occur, for example, where the cytoplasmic membranes of adjacent epithelial cells are closely apposed. It consists of a circular region of each membrane together with associated intracellular microfilaments and an intercellular material which may include, for example, mucopolysaccharides. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990; Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
MSH

A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. [GOC:mah, GOC:mtg_muscle, ISBN:0815332181]
GO

Desmosomes are intercellular anchoring junctions that anchor intermediate filaments at membrane-associated plaques in adjoining cells. Desmosomes assemble in response to cell-cell contact and raised levels of extracellular calcium. Sensitivity to calcium levels is lost as desmosomes mature.
NCI

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koně

Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.
MSH

large solid-hoofed herbivorous mammal (Equus caballus, family Equidae, the horse family) domesticated since a prehistoric period and used as a beast of burden, a draft animal, or for riding.
CSP

The domestic horse, Equus caballus.
NCI

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virus ptačí encefalomyelitidy

A tentative species in the genus HEPATOVIRUS infecting primarily young chicks, but also found in turkeys, pheasants, and guinea fowl. It causes a fatal neuronal degeneration and is transmitted by mechanical contact.
MSH

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RNA ribozomální 5S

Constituent of the 50S subunit of prokaryotic ribosomes containing about 120 nucleotides and 34 proteins. It is also a constituent of the 60S subunit of eukaryotic ribosomes. 5S rRNA is involved in initiation of polypeptide synthesis.
MSH

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řízení ošetřovatelství – výzkum

Research concerned with establishing costs of nursing care, examining the relationships between nursing services and quality patient care, and viewing problems of nursing service delivery within the broader context of policy analysis and delivery of health services (from a national study, presented at the 1985 Council on Graduate Education for Administration in Nursing (CGEAN) meeting).
MSH

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nosní sliznice

The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells.
MSH

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diabetes mellitus lipoatrofický

A type of diabetes mellitus that is characterized by severe INSULIN RESISTANCE and LIPODYSTROPHY. The latter may be generalized, partial, acquired, or congenital (LIPODYSTROPHY, CONGENITAL GENERALIZED).
MSH

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porodnice

Special hospitals which provide care to women during pregnancy and parturition.
MSH

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kyselina azetidinkarboxylová

A proline analog that acts as a stoichiometric replacement of proline. It causes the production of abnormal proteins with impaired biological activity.
MSH

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horečka Skalistých hor

An acute febrile illness caused by RICKETTSIA RICKETTSII. It is transmitted to humans by bites of infected ticks and occurs only in North and South America. Characteristics include a sudden onset with headache and chills and fever lasting about two to three weeks. A cutaneous rash commonly appears on the extremities and trunk about the fourth day of illness.
MSH

acute, infectious, sometimes fatal disease caused by Rickettsia rickettsii usually transmitted by ixodid ticks; occurs only in North and South America; manifestations include chills, fever, rash, headache, myalgia, and prostration.
CSP

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nokturie

Frequent URINATION at night that interrupts sleep. It is often associated with outflow obstruction, DIABETES MELLITUS, or bladder inflammation (CYSTITIS).
MSH

Frequent episodes of urination during the night.
NCI

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4-chlor-7-nitrobenzofurazan

A benzofuran derivative used as a protein reagent since the terminal N-NBD-protein conjugate possesses interesting fluorescence and spectral properties. It has also been used as a covalent inhibitor of both beef heart mitochondrial ATPase and bacterial ATPase.
MSH

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diagnostic use

Used with chemical compounds, drugs, and physical agents when these substances are used for studies of clinical function of an organ, or for the diagnosis of human or animal diseases.
MSH

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Deltaretrovirus – antigeny

Antigens associated with the DELTARETROVIRUS; HTLV-I ANTIGENS and HTLV-II ANTIGENS belong to this group.
MSH

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bacitracin

A complex of cyclic peptide antibiotics produced by the Tracy-I strain of Bacillus subtilis. The commercial preparation is a mixture of at least nine bacitracins with bacitracin A as the major constituent. It is used topically to treat open infections such as infected eczema and infected dermal ulcers. (From Goodman and Gilman, The Pharmacological Basis of Therapeutics, 8th ed, p1140)
MSH

A complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall. The binding interferes with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and prevents peptidoglycan synthesis, thereby inhibiting bacterial cell growth.
NCI

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roxithromycin

Semisynthetic derivative of erythromycin. It is concentrated by human phagocytes and is bioactive intracellularly. While the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections.
MSH

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pracovní lékařství

Medical specialty concerned with the promotion and maintenance of the physical and mental health of employees in occupational settings.
MSH

medical specialty concerned with the promotion and maintenance of the physical and mental health of employees in occupational settings; do not confuse with OCCUPATIONAL HEALTH/SAFETY, the health and safety of the worker.
CSP

This branch of medicine is concerned with the prevention, diagnosis, and treatment of injuries and illnesses that occur at the workplace or as a result of toxic exposures, stress, or accidents at the workplace. Occupational medicine encompasses issues such as industrial hygiene, safety, pollution control, ergonomics, industrial and agricultural toxicology, disability evaluation, physical rehabilitation, industrial psychology and emergency medicine. (BioTech Life Science Dictionary)
NCI

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Nematospiroides dubius

A species of intestinal nematode parasites which occur most commonly in mice. Infection is by ingesting larvae. This particular species is used extensively in immunological research.
MSH

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dibukain

A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
MSH

A quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane. Inhibition of sodium channels prevents the depolarization of nerve cell membranes and inhibits subsequent propagation of impulses along the course of the nerve, thereby limiting the excitation of nerve endings. This results in loss of sensation.
NCI

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Hydantoin

group of anticonvulsants containing an allantoin heterocyclic base.
CSP

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Bagasóza

A diffuse parenchymal lung disease caused by inhaled dust from processing SUGARCANE (bagasse), usually in the manufacturing of wallboard.
MSH

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