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enzymology

Used with organisms, except vertebrates, and with organs and tissues. It is also used with diseases for enzymes during the course of the disease, but excludes diagnostic enzyme tests, for which “diagnosis” is used.
MSH

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poslech

Act of listening for sounds within the body.
MSH

Listening with a device, such as a stethoscope, to anatomical locations that produce audible sounds like the heart, lungs and abdomen.
NCI

the act of listening for sounds made by internal organs, as the heart and lungs
CHV

Listening with a device, such as a stethoscope, to anatomical locations that produce audible sounds like the heart, lungs and abdomen.
NCI

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aminobifenylové sloučeniny

Biphenyl compounds substituted in any position by one or more amino groups. Permitted are any substituents except fused rings.
MSH

nitrogen substituted aromatic amine formerly used in dyemaking; now used to induce cancer in laboratory animals.
CSP

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Interferon Alfa-2a

A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. (NCI04) Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=467189&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=467189&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1952″ NCI Thesaurus)
PDQ

A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. (NCI04)
NCI

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desmozómy

A type of junction that attaches one cell to its neighbor. One of a number of differentiated regions which occur, for example, where the cytoplasmic membranes of adjacent epithelial cells are closely apposed. It consists of a circular region of each membrane together with associated intracellular microfilaments and an intercellular material which may include, for example, mucopolysaccharides. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990; Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
MSH

A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism. [GOC:mah, GOC:mtg_muscle, ISBN:0815332181]
GO

Desmosomes are intercellular anchoring junctions that anchor intermediate filaments at membrane-associated plaques in adjoining cells. Desmosomes assemble in response to cell-cell contact and raised levels of extracellular calcium. Sensitivity to calcium levels is lost as desmosomes mature.
NCI

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rektum – nádory

Tumors or cancer of the RECTUM.
MSH

new abnormal rectal or anal tissue that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
CSP

Either benign or malignant growth of tissue in rectum, the terminal portion of the digestive tube.
NCI

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epilepsie generalizovaná

Recurrent conditions characterized by epileptic seizures which arise diffusely and simultaneously from both hemispheres of the brain. Classification is generally based upon motor manifestations of the seizure (e.g., convulsive, nonconvulsive, akinetic, atonic, etc.) or etiology (e.g., idiopathic, cryptogenic, and symptomatic). (From Mayo Clin Proc, 1996 Apr;71(4):405-14)
MSH

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virus ptačí encefalomyelitidy

A tentative species in the genus HEPATOVIRUS infecting primarily young chicks, but also found in turkeys, pheasants, and guinea fowl. It causes a fatal neuronal degeneration and is transmitted by mechanical contact.
MSH

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síran amonný

Sulfuric acid diammonium salt. It is used in CHEMICAL FRACTIONATION of proteins.
MSH

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mezinárodní soustava jednotek

A system of physical units in which the fundamental quantities are length, time, mass, electric current, temperature, luminous intensity, and amount of substance, and the corresponding units are the meter, second, kilogram, ampere, kelvin, candela, and mole. The system has been given official status and recommended for universal use by the General Conference on Weights and Measures.
MSH

The International System of Units (Systeme International d`Unites, SI) is a decimal system of weights and measures derived from and extending the metric system of units established through the Treaty of the Meter (Convention du Metre) signed in Paris in 1875 and currently signed by 48 nations including all the major industrialized countries. The SI is maintained by the International Bureau of Weights and Measures (BIPM, for Bureau International des Poids et Mesures), and is updated every few years by an international conference, the General Conference on Weights and Measures (CGPM, for Conference Generale des Poids et Mesures). SI has a short list of base units defined in an absolute way without referring to any other units: the metre, the kilogram, the second, the ampere, the kelvin, the mole, and the candela. The base units are consistent with the part of the metric system called the MKS system.
NCI

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diabetes mellitus lipoatrofický

A type of diabetes mellitus that is characterized by severe INSULIN RESISTANCE and LIPODYSTROPHY. The latter may be generalized, partial, acquired, or congenital (LIPODYSTROPHY, CONGENITAL GENERALIZED).
MSH

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refrakterní doba psychologická

A delayed response interval occurring when two stimuli are presented in close succession.
MSH

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virus infekční anémie koní

A species of LENTIVIRUS, subgenus equine lentiviruses (LENTIVIRUSES, EQUINE), causing acute and chronic infection in horses. It is transmitted mechanically by biting flies, mosquitoes, and midges, and iatrogenically through unsterilized equipment. Chronic infection often consists of acute episodes with remissions.
MSH

species of Lentivirus, subgenus equine lentiviruses, causing acute and chronic infection in horses; transmitted mechanically by biting flies, mosquitoes, and midges, and iatrogenically through unsterilized equipment.
CSP

A species of lentivirus, subgenus equine lentiviruses, causing acute and chronic infection in horses. It is transmitted mechanically by biting flies, mosquitoes, and midges, and iatrogenically through unsterilized equipment. Chronic infection often consists of acute episodes with remissions.
NCI

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kyselina azetidinkarboxylová

A proline analog that acts as a stoichiometric replacement of proline. It causes the production of abnormal proteins with impaired biological activity.
MSH

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amrinon

A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
MSH

A synthetic bipyridine phosphodiesterase inhibitor with inotropic and vasodilator properties. Inamrinone inhibits type III phosphodiesterase, which is abundant in cardiac and vascular tissues, thereby preventing the degradation of cyclic adenosine monophosphate (cAMP) and increasing intracellular concentrations of this secondary messenger. Elevated levels of cAMP increase the contractile force of the cardiac muscle and produce positive inotropic effects. Although the mechanism of action is not fully understood, inamrinone causes smooth muscle relaxation, resulting in peripheral vasodilation (reduced afterload) and a decreased pulmonary vascular resistance (reduced preload).
NCI

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intracelulární membrány

Thin structures that encapsulate subcellular structures or ORGANELLES in EUKARYOTIC CELLS. They include a variety of membranes associated with the CELL NUCLEUS; the MITOCHONDRIA; the GOLGI APPARATUS; the ENDOPLASMIC RETICULUM; LYSOSOMES; PLASTIDS; and VACUOLES.
MSH

membranes of subcellular structures.
CSP

A thin pliable sheet separating organelles from the protoplasm.
NCI

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diagnostic use

Used with chemical compounds, drugs, and physical agents when these substances are used for studies of clinical function of an organ, or for the diagnosis of human or animal diseases.
MSH

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návratná horečka

An acute infection characterized by recurrent episodes of PYREXIA alternating with asymptomatic intervals of apparent recovery. This condition is caused by SPIROCHETES of the genus BORRELIA. It is transmitted by the BITES of either the body louse (PEDICULUS humanus corporis), for which humans are the reservoir, or by soft ticks of the genus ORNITHODOROS, for which rodents and other animals are the principal reservoirs.
MSH

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erythema chronicum migrans

A deep type of gyrate erythema that follows a bite by an ixodid tick; it is a stage-1 manifestation of LYME DISEASE. The site of the bite is characterized by a red papule that expands peripherally as a nonscaling, palpable band that clears centrally. This condition is often associated with systemic symptoms such as chills, fever, headache, malaise, nausea, vomiting, fatigue, backache, and stiff neck.
MSH

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bacitracin

A complex of cyclic peptide antibiotics produced by the Tracy-I strain of Bacillus subtilis. The commercial preparation is a mixture of at least nine bacitracins with bacitracin A as the major constituent. It is used topically to treat open infections such as infected eczema and infected dermal ulcers. (From Goodman and Gilman, The Pharmacological Basis of Therapeutics, 8th ed, p1140)
MSH

A complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall. The binding interferes with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and prevents peptidoglycan synthesis, thereby inhibiting bacterial cell growth.
NCI

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anafylatoxiny

Serum peptides derived from certain cleaved COMPLEMENT PROTEINS during COMPLEMENT ACTIVATION. They induce smooth MUSCLE CONTRACTION; mast cell HISTAMINE RELEASE; PLATELET AGGREGATION; and act as mediators of the local inflammatory process. The order of anaphylatoxin activity from the strongest to the weakest is C5a, C3a, C4a, and C5a des-arginine.
MSH

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jod

A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
MSH

nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90; it is a nutritionally essential element and is especially important in thyroid hormone synthesis; in solution, it has anti-infective properties and is used topically.
CSP

An element that is necessary for the body to make thyroid hormone. It is found in shellfish and iodized salt.
NCI

An element with atomic symbol I, atomic number 53, and atomic weight of 126.90.
NCI

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dibukain

A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
MSH

A quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane. Inhibition of sodium channels prevents the depolarization of nerve cell membranes and inhibits subsequent propagation of impulses along the course of the nerve, thereby limiting the excitation of nerve endings. This results in loss of sensation.
NCI

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poranění z opakovaného přetěžování

Harmful and painful condition caused by overuse or overexertion of some part of the musculoskeletal system, often resulting from work-related physical activities. It is characterized by inflammation, pain, or dysfunction of the involved joints, bones, ligaments, and nerves.
MSH

damage inflicted on any part of the body due to overexertion of some part of the musculoskeletal system, often resulting from work-related physical activities.
CSP

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Escherichia

genus of gram negative, facultatively anaerobic, rod shaped bacteria found in the large intestine of warm blooded animals; nonpathogenic or opportunistic.
CSP

A genus of gram-negative, facultatively anaerobic, rod-shaped bacteria whose organisms occur in the lower part of the intestine of warm-blooded animals. The species are either nonpathogenic or opportunistic pathogens.
MSH

A genus of Gram-negative, non-spore forming, facultatively anaerobic, rod-shaped bacteria in the phylum Proteobacteria.
NCI

Any bacteria that is not assigned to the species level but can be assigned to the Escherichia genus level.
NCI

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Bagasóza

A diffuse parenchymal lung disease caused by inhaled dust from processing SUGARCANE (bagasse), usually in the manufacturing of wallboard.
MSH

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ipodát

Ionic monomeric contrast media. Usually the sodium or calcium salts are used for examination of the gall bladder and biliary tract. (From Martindale, The Extra Pharmacopoeia, 30th ed, p704)
MSH

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dienestrol

A synthetic, non-steroidal estrogen structurally related to stilbestrol. It is used, usually as the cream, in the treatment of menopausal and postmenopausal symptoms.
MSH

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dýchání – poruchy

Diseases of the respiratory system in general or unspecified or for a specific respiratory disease not available.
MSH

condition in which there is a deviation from or interruption of the normal structure or function of the respiratory system.
CSP

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estetika

The branch of philosophy dealing with the nature of the beautiful. It includes beauty, esthetic experience, esthetic judgment, esthetic aspects of medicine, etc.
MSH

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