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N-formylmethionin-leucyl-fenylalanin

N-Formylmethionyl-leucyl-phenylalanine. A formylated tripeptide originally isolated from bacterial filtrates that is positively chemotactic to polymorphonuclear leucocytes, and causes them to release lysosomal enzymes and become metabolically activated.
MSH

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patela

The flat, triangular bone situated at the anterior part of the KNEE.
MSH

A small flat triangular bone in front of the knee that articulates with the femur and protects the knee joint. (NCI)
NCI

A small flat triangular bone in front of the knee that articulates with the femur and protects the knee joint.
NCI

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holothurin

A highly toxic saponin occurring in HOLOTHUROIDEA. This marine toxin is an anionic surfactant, hemolyzing ERYTHROCYTES.
MSH

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difuzní komory kultivační

Devices used in a technique by which cells or tissues are grown in vitro or, by implantation, in vivo within chambers permeable to diffusion of solutes across the chamber walls. The chambers are used for studies of drug effects, osmotic responses, cytogenic and immunologic phenomena, metabolism, etc., and include tissue cages.
MSH

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Beclomethasone Dipropionate

The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.
NCI

The dipropionate salt of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39272&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39272&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C299″ NCI Thesaurus)
PDQ

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Penicillin G Sodium

The sodium salt form of benzylpenicillin, a semi-synthetic, broad-spectrum penicillin antibiotic with bactericidal activity. Benzylpenicillin sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
NCI

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naled

An organophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
MSH

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přemístění pacientů

Interfacility or intrahospital transfer of patients. Intrahospital transfer is usually to obtain a specific kind of care and interfacility transfer is usually for economic reasons as well as type of care provided.
MSH

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koně

Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.
MSH

large solid-hoofed herbivorous mammal (Equus caballus, family Equidae, the horse family) domesticated since a prehistoric period and used as a beast of burden, a draft animal, or for riding.
CSP

The domestic horse, Equus caballus.
NCI

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dihydropteridinreduktasa

An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.
MSH

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bencyklan

A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
MSH

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somatostatinom

A SOMATOSTATIN-secreting tumor derived from the pancreatic delta cells (SOMATOSTATIN-SECRETING CELLS). It is also found in the INTESTINE. Somatostatinomas are associated with DIABETES MELLITUS; CHOLELITHIASIS; STEATORRHEA; and HYPOCHLORHYDRIA. The majority of somatostatinomas have the potential for METASTASIS.
MSH

A rare, usually malignant tumor arizing from delta cells. This neoplasm produces large amounts of somatostatin, which may result in a syndrome characterized by diarrhea, steatorrhea, weight loss, and gastric hyposecretion. Sixty percent are found in the pancreas and 40% in the duodenum or jejunum. The peak incidence occurs between 40 and 60 years of age; women are affected more than men by 2:1.
NCI

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nosní sliznice

The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells.
MSH

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pánev – infekce

Infection involving the tissues or organs in the PELVIS.
MSH

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porodnice

Special hospitals which provide care to women during pregnancy and parturition.
MSH

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dimethylnitrosamin

A nitrosamine derivative with alkylating, carcinogenic, and mutagenic properties. It causes serious liver damage and is a hepatocarcinogen in rodents.
MSH

A volatile, combustible, yellow, oily liquid nitrosamine with a faint characteristic odor that decomposes when exposed to light and emits toxic fumes of nitrogen oxides when heated to decomposition. N-Nitrosodimethylamine is primarily used in laboratory research to induce tumors in experimental animals. This substance may be formed during the cooking of foods, especially cured meats and fish, that contain sodium nitrite as a preservative, but is also found in several vegetables, cheeses, alcoholic beverages and fruits, and as a contaminant in rubber products. Exposure to NNitrosodimethylamine irritates the skin and eyes and damages the liver. This substance is reasonably anticipated to be a human carcinogen. (NCI05)
NCI

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benzofurany

Compounds that contain a BENZENE ring fused to a furan ring.
MSH

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spasmus

An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.
MSH

a sudden, violent, involuntary contraction of a muscle or a group of muscles, attended by pain and interference with function, producing involuntary movement and distortion.
CSP

A sudden, violent, involuntary contraction of a muscle or group of muscles.
NCI

A sudden contraction of a muscle or group of muscles, such as a cramp.
NCI

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4-chlor-7-nitrobenzofurazan

A benzofuran derivative used as a protein reagent since the terminal N-NBD-protein conjugate possesses interesting fluorescence and spectral properties. It has also been used as a covalent inhibitor of both beef heart mitochondrial ATPase and bacterial ATPase.
MSH

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penze

Fixed sums paid regularly to individuals.
MSH

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Deltaretrovirus – antigeny

Antigens associated with the DELTARETROVIRUS; HTLV-I ANTIGENS and HTLV-II ANTIGENS belong to this group.
MSH

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diftérie

A localized infection of mucous membranes or skin caused by toxigenic strains of CORYNEBACTERIUM DIPHTHERIAE. It is characterized by the presence of a pseudomembrane at the site of infection. DIPHTHERIA TOXIN, produced by C. diphtheriae, can cause myocarditis, polyneuritis, and other systemic toxic effects.
MSH

localized infection of mucous membranes or skin caused by toxigenic strains of Corynebacterium diphtheriae; it is characterized by the presence of a pseudomembrane at the site of infection; diphtheria toxin, produced by C. diphtheriae, can cause myocarditis, polyneuritis, and other systemic toxic effects.
CSP

Diphtheria is a serious bacterial infection. You can catch it from a person who has the infection and coughs or sneezes. It usually affects the nose and throat and causes a bad sore throat, swollen glands, fever and chills. But if it is not properly diagnosed and treated it produces a poison in the body that can cause serious complications such as heart failure or paralysis.

The diphtheria, pertussis and tetanus (DPT) vaccine can prevent diphtheria, but its protection does not last forever. Adults should get another dose, or booster, every 10 years. Diphtheria is very rare in the United States because of the vaccine.

Centers for Disease Control and Prevention


MEDLINEPLUS

A Gram-positive bacterial infection caused by Corynebacterium diphtheria. It usually involves the oral cavity, pharynx, and nasal cavity. Patients develop pseudomembranes in the affected areas and manifest signs and symptoms of an upper respiratory infection. The diphtheria toxin may cause myocarditis, polyneuritis, and other systemic effects.
NCI

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berylióza

A form of pneumoconiosis caused by inhaled rare metal BERYLLIUM or its soluble salts which are used in a wide variety of industry including alloys, ceramics, radiographic equipment, and vacuum tubes. Berylliosis is characterized by an acute inflammatory reaction in the upper airway leading to BRONCHIOLITIS; PULMONARY EDEMA; and pneumonia.
MSH

lung disease caused by exposure to metallic beryllium or its soluble salts.
CSP

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řeč – artikulační testy

Tests of accuracy in pronouncing speech sounds, e.g., Iowa Pressure Articulation Test, Deep Test of Articulation, Templin-Darley Tests of Articulation, Goldman-Fristoe Test of Articulation, Screening Speech Articulation Test, Arizona Articulation Proficiency Scale.
MSH

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Nematospiroides dubius

A species of intestinal nematode parasites which occur most commonly in mice. Infection is by ingesting larvae. This particular species is used extensively in immunological research.
MSH

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peptidy – faktory zahájení

Protein factors uniquely required during the initiation phase of protein synthesis in GENETIC TRANSLATION.
MSH

One of several soluble proteins involved in the initiation of protein or RNA synthesis. (On-line Medical Dictionary)
NCI

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Hydantoin

group of anticonvulsants containing an allantoin heterocyclic base.
CSP

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diskriminační učení

learning that is manifested in the ability to respond differentially to various stimuli.
CSP

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dispozice (epidemiologie)

Any deviation of results or inferences from the truth, or processes leading to such deviation. Bias can result from several sources: one-sided or systematic variations in measurement from the true value (systematic error); flaws in study design; deviation of inferences, interpretations, or analyses based on flawed data or data collection; etc. There is no sense of prejudice or subjectivity implied in the assessment of bias under these conditions.
MSH

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spermidin

A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
MSH

polyamine found in most tissues in association with nucleic acids; formed from putrescine and a precursor of spermine.
CSP

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