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Nitrophenol

any organic compound containing one or more hydroxyl groups and nitro groups attached to a benzene ring.
CSP

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biologická psychiatrie

An interdisciplinary science concerned with studies of the biological bases of behavior – biochemical, genetic, physiological, and neurological – and applying these to the understanding and treatment of mental illness.
MSH

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ileocekální chlopeň

The valve, at the junction of the CECUM with the COLON, that guards the opening where the ILEUM enters the LARGE INTESTINE.
MSH

The valve between the ileum of the small intestine and the cecum of the large intestine.
NCI

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retinoidy

A group of tetraterpenes, with four terpene units joined head-to-tail. Biologically active members of this class are used clinically in the treatment of severe cystic ACNE; PSORIASIS; and other disorders of keratinization.
MSH

retinol and its derivatives; C(20) polyunsaturated, cyclic, lipid soluble alcohol; deficiency results in night blindness and certain epithelial disorders.
CSP

A nutrient that the body needs in small amounts to function and stay healthy. Retinoic acid is made in the body from vitamin A and helps cells to grow and develop, especially in the embryo. A form of retinoic acid made in the laboratory is put on the skin to treat conditions such as acne and is taken by mouth to treat acute promyelocytic leukemia (a fast-growing cancer in which there are too many immature blood-forming cells in the blood and bone marrow). Retinoic acid is being studied in the prevention and treatment of other types of cancer.
NCI

Class of compounds consisting of four isoprenoid units joined in a head-to-tail manner and customarily containing five conjugated double bonds.
NCI

A group of agents that includes retinol (Vitamin A) and related compounds with potential antineoplastic and/or chemopreventive activities. A retinoic acid agent binds to and/or activates specific nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs), thereby modulating transcription of genes responsible for cell differentiation and proliferation. A retinoic acid agent may exhibit immunomodulatory and anti-inflammatory properties and may inhibit ornithine decarboxylase, resulting in a decrease in polyamine synthesis and keratinization. (NCI04)
NCI

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psi

The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker`s Mammals of the World, 5th ed, p1065)
MSH

The domestic dog, Canis familiaris.
NCI

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terminologické slovníky

Work consisting of lists of the technical terms or expressions used in a specific field. These lists may or may not be formally adopted or sanctioned by usage.
MSH

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bipolární poruchy

A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
MSH

Bipolar disorder is a serious mental illness. People who have it experience dramatic mood swings. They may go from overly energetic, "high" and/or irritable, to sad and hopeless, and then back again. They often have normal moods in between. The up feeling is called mania. The down feeling is depression.

Bipolar disorder can run in families. It usually starts in late adolescence or early adulthood. If you think you may have it, tell your health care provider. A medical checkup can rule out other illnesses that might cause your mood changes.

Untreated, bipolar disorder can result in damaged relationships, poor job or school performance, and even suicide. However, there are effective treatments: medicines and "talk therapy". A combination usually works best.

NIH: National Institute of Mental Health


MEDLINEPLUS

A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. (MeSH)
NCI

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imunologická tolerance

The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
MSH

An innate tolerance that prevents the body from attacking native proteins and tissue.
NCI

The failure of the immune system to respond to an antigen that previously caused an immune response.
NCI

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rhamnosa

A methylpentose whose L- isomer is found naturally in many plant glycosides and some gram-negative bacterial lipopolysaccharides.
MSH

A pentose which is a 6-deoxy mannose. It has a structure like mannose with the OH group at carbon-6 (in Fisher projection) replaced by H.
NCI

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doxepin

A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
MSH

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North Carolina

A state in the mid-atlantic United States. Its capital is Raleigh.
NCI

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