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konzervovaná sekvence

A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.
MSH

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Hominidae

Family of the suborder HAPLORHINI (Anthropoidea) comprising bipedal primate MAMMALS. It includes modern man (HOMO SAPIENS) and the great apes: gorillas (GORILLA GORILLA), chimpanzees (PAN PANISCUS and PAN TROGLODYTES), and orangutans (PONGO PYGMAEUS).
MSH

A taxonomic family that was originally restricted to humans and their extinct relatives, but now also includes the gorilla, orangutan, chimpanzee and bonobo.
NCI

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arteria retinalis – okluze

Sudden ISCHEMIA in the RETINA due to blocked blood flow through the CENTRAL RETINAL ARTERY or its branches leading to sudden complete or partial loss of vision, respectively, in the eye.
MSH

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nafazolin

An adrenergic vasoconstrictor agent used as a decongestant.
MSH

An imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive activity. Upon ocular administration, naphazoline exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness.
NCI

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antikoncepční látky orální hormonální

Oral contraceptives which owe their effectiveness to hormonal preparations.
MSH

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nemocniční informační systémy

Integrated, computer-assisted systems designed to store, manipulate, and retrieve information concerned with the administrative and clinical aspects of providing medical services within the hospital.
MSH

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Retroviridae

family of RNA viruses that infects birds and mammals and encodes the enzyme reverse transcriptase; a key feature of retrovirus biology is the synthesis of a DNA copy of the genome which is integrated into cellular DNA; after integration it is sometimes not expressed but maintained in a latent state.
CSP

Family of RNA viruses that infects birds and mammals and encodes the enzyme reverse transcriptase. The family contains seven genera: DELTARETROVIRUS; LENTIVIRUS; RETROVIRUSES TYPE B, MAMMALIAN; ALPHARETROVIRUS; GAMMARETROVIRUS; RETROVIRUSES TYPE D; and SPUMAVIRUS. A key feature of retrovirus biology is the synthesis of a DNA copy of the genome which is integrated into cellular DNA. After integration it is sometimes not expressed but maintained in a latent state (PROVIRUSES).
MSH

A type of virus that has RNA instead of DNA as its genetic material. It uses an enzyme called reverse transcriptase to become part of the host cells` DNA. This allows many copies of the virus to be made in the host cells. The virus that causes AIDS, the human immunodeficiency virus (HIV), is a type of retrovirus.
NCI

A family of viruses that possess RNA-dependent DNA polymerases (reverse transcriptases) and contain two identical molecules of positive sense, single-stranded RNA of high molecular weight. This RNA serves as a template for the synthesis of a complementary DNA, which may be integrated into the host DNA. Virions are enveloped.
NCI

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natamycin

Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically.
MSH

A polyene amphoteric macrolide antibiotic with antifungal properties. Natamycin exerts its antifungal effects by binding to sterols in the fungal cell membrane thereby increasing membrane permeability. This leads to a leakage and loss of essential cellular constituents. Following ocular application, natamycin is retained in the conjunctival fornices and attains effective concentrations within the corneal stroma where it exerts its effect.
NCI

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koproporfyriny

Porphyrins with four methyl and four propionic acid side chains attached to the pyrrole rings. Elevated levels of Coproporphyrin III in the urine and feces are major findings in patients with HEREDITARY COPROPORPHYRIA.
MSH

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nemocnice speciální

Hospitals which provide care for a single category of illness with facilities and staff directed toward a specific service.
MSH

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celoroční alergická rýma

Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.
MSH

Allergic rhinitis caused by indoor allergens and lasting year round.
NCI

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krční svaly

Muscle (organ) which is a part of the neck. Examples: platysma, sternocleidomastoid, cricothyroid muscle.
UWDA

The neck muscles consist of the platysma, splenius cervicis, sternocleidomastoid(eus), longus colli, the anterior, medius, and posterior scalenes, digastric(us), stylohyoid(eus), mylohyoid(eus), geniohyoid(eus), sternohyoid(eus), omohyoid(eus), sternothyroid(eus), and thyrohyoid(eus).
MSH

Muscle organ which is a part of the neck. Examples: platysma, sternocleidomastoid, cricothyroid muscle.
FMA

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corpora allata

Paired or fused ganglion-like bodies in the head of insects. The bodies secrete hormones important in the regulation of metamorphosis and the development of some adult tissues.
MSH

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experimenty na lidech

The use of humans as investigational subjects.
MSH

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ribitol

A sugar alcohol formed by the reduction of ribose.
MSH

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anémie sideroblastická

Anemia characterized by the presence of erythroblasts containing excessive deposits of iron in the marrow.
MSH

acquired or hereditary anemia marked by sideroblasts: bone marrow cells with large mitochondrial deposits of insoluble iron due to defective heme synthesis, leading to ineffective erythropoiesis.
CSP

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neonatologie

A subspecialty of Pediatrics concerned with the newborn infant.
MSH

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kotinin

The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.
MSH

The major metabolite of nicotine.
NCI

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hydroa vacciniforme

A vesicular and bullous eruption having a tendency to recur in summer during childhood and commonly appearing on sun-exposed skin. The lesions are surrounded by an erythematous zone and resemble a vaccination. (From Dorland, 27th ed)
MSH

A rare skin disorder of unknown etiology affecting children. It is a photodermatitis, characterized by the formation of vesicles and scarring on sun exposed areas.
NCI

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Rickettsia typhi

The etiologic agent of murine typhus (see TYPHUS, ENDEMIC FLEA-BORNE).
MSH

Any bacterial organism that can be assigned to the species Rickettsia typhi.
NCI

A species of aerobic, Gram negative, rod and cocci shaped bacteria assigned to the phylum Proteobacteria. This species is obligately intracellular, motile and transmitted to humans by a tick or flea host. R. typhi is a pathogen that causes murine typhus.
NCI

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angiografie

radiography of blood vessels after injection of a contrast medium.
CSP

A procedure to x-ray blood vessels. The blood vessels can be seen because of an injection of a dye that shows up in the x-ray.
NCI

An x-ray of blood vessels. The person receives an injection of dye to outline the vessels on the x-ray.
NCI

The X-ray examination of the blood vessels or chambers of the heart.
NCI

An X-ray representation of blood vessels made after the injection of a radiopaque substance.
NCI

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jaderné štěpení

Nuclear reaction in which the nucleus of a heavy atom such as uranium or plutonium is split into two approximately equal parts by a neutron, charged particle, or photon.
MSH

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neovaskularizace patologická

A pathologic process consisting in proliferation of blood vessels in abnormal tissues or in abnormal positions.
MSH

The formation of new or recent blood vessels. The vasculature network is critical to the development of neoplasms. As the tumor burden grows, vascular endothial cells are recruited to form new blood vessels as an increased demand for blood and nourishment is required.
NCI

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kraniologie

The scientific study of variations in size, shape, and proportion of the cranium.
MSH

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hydroquinone

1,4-dihydroxybenzene.
CSP

Produced as an inhibitor, an antioxidant, and an intermediate in the synthesis of dyes, motor fuels, and oils; in photographic processing; and naturally in certain plant species, Hydroquinone is a phenol derivative with antioxidant properties that can cause toxicity in several organs, notably the kidney. Used as a topical treatment for skin hyperpigmentation and in various cosmetic products, it is metabolized mainly to glutathione conjugates and forms mutagenic DNA adducts in in-vitro systems. (NCI04)
NCI

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RNA-polymerasa III

A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure where it transcribes DNA into RNA. It has specific requirements for cations and salt and has shown an intermediate sensitivity to alpha-amanitin in comparison to RNA polymerase I and II. EC 2.7.7.6.
MSH

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práva zvířat

The moral and ethical bases of the protection of animals from cruelty and abuse. The rights are extended to domestic animals, laboratory animals, and wild animals.
MSH

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nukleotiddeaminasa

Catalyze the hydrolysis of nucleotides with the elimination of ammonia.
MSH

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nervový systém – nemoci

Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
MSH

Any deviation from the normal structure or function of the nervous system that is manifested by a characteristic set of symptoms and signs. (NCI)
NCI

impairment of health or a condition of abnormal functioning of the nervous system.
CSP

Any deviation from the normal structure or function of the nervous system that is manifested by a characteristic set of symptoms and signs.
NCI

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kritický stav

A disease or state in which death is possible or imminent.
MSH

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