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chinonreduktasy

NAD(P)H:(quinone acceptor) oxidoreductases. A family that includes three enzymes which are distinguished by their sensitivity to various inhibitors. EC 1.6.99.2 (NAD(P)H DEHYDROGENASE (QUINONE);) is a flavoprotein which reduces various quinones in the presence of NADH or NADPH and is inhibited by dicoumarol. EC 1.6.99.5 (NADH dehydrogenase (quinone)) requires NADH, is inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. EC 1.6.99.6 (NADPH dehydrogenase (quinone)) requires NADPH and is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol.
MSH

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Motieven

A benefit, consideration, or positive motivational influence, financial or otherwise, given to induce a specific action.
NCI

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atopická dermatitida

A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
MSH

chronic inflammatory skin disorder in individuals with a hereditary predisposition to a lowered threshold to pruritus; characterized by extreme itching, leading to scratching and rubbing that result in typical lesions of eczema.
CSP

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alkuronium

A non-depolarizing skeletal muscle relaxant similar to TUBOCURARINE. It is used as an anesthesia adjuvant.
MSH

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autoimunitní nemoci

Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
MSH

heading term for a diverse group of disorders characterized by pathologenic immune reactions to autologous (self) tissue; for nonnpatholgical, developmental, or phenomenological aspects of autoimmunity, use AUTOIMMUNITY.
CSP

A condition in which the body recognizes its own tissues as foreign and directs an immune response against them.
NCI

Your body`s immune system protects you from disease and infection. But if you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Autoimmune diseases can affect many parts of the body. These diseases tend to run in families. Women – particularly African-American, Hispanic-American, and Native-American women – have a higher risk for some autoimmune diseases.

There are more than 80 types of autoimmune diseases, and some have similar symptoms. This makes it hard for your health care provider to know if you really have one of these diseases, and if so, which one. Getting diagnosed can be frustrating and stressful. In many people, the first symptoms are being tired, muscle aches and low fever.

The diseases may also have flare-ups, when they get worse, and remissions, when they all but disappear. The diseases do not usually go away, but symptoms can be treated.


MEDLINEPLUS

A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents.
NCI

A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis).
NCI

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záření – látky senzibilizující

Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells.
MSH

chemotherapeutic agent used to enhance the effect of radiation therapy.
CSP

Drugs that make tumor cells more sensitive to radiation therapy.
NCI

An agent that makes tumor cells more sensitive to radiation therapy.
NCI

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individualita

Those psychological characteristics which differentiate individuals from one another.
MSH

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rozvojové země

Countries in the process of change directed toward economic growth, that is, an increase in production, per capita consumption, and income. The process of economic growth involves better utilization of natural and human resources, which results in a change in the social, political, and economic structures.
MSH

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alkylsulfonany

any compound of the type R-SO3-.
CSP

Organic esters or salts of sulfonic acid derivatives containing an aliphatic hydrocarbon radical.
MSH

An ester of alkane sulfonic acid that acts as an alkylating agent.
NCI

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učení vyhýbat se

A response to a cue that is instrumental in avoiding a noxious experience.
MSH

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radioligandová zkouška

Quantitative determination of receptor (binding) proteins in body fluids or tissue using radioactively labeled binding reagents (e.g., antibodies, intracellular receptors, plasma binders).
MSH

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novorozenec malý vzhledem ke gestačnímu věku

An infant having a birth weight lower than expected for its gestational age.
MSH

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diagnóza

The determination of the nature of a disease or condition, or the distinguishing of one disease or condition from another. Assessment may be made through physical examination, laboratory tests, or the likes. Computerized programs may be used to enhance the decision-making process.
MSH

general term for detecting and classifying diseases.
CSP

The process of identifying a disease, such as cancer, from its signs and symptoms.
NCI

Set of codes depicting clinical disease and conditions


HL7V3.0

The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation.
NCI

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mucinóza folikulární

A disease of the pilosebaceous unit, presenting clinically as grouped follicular papules or plaques with associated hair loss. It is caused by mucinous infiltration of tissues, and usually involving the scalp, face, and neck. It may be primary (idiopathic) or secondary to mycosis fungoides or reticulosis.
MSH

A rare dermatologic disorder characterized by the accumulation of mucinous material in the hair follicles. In some cases it is associated with lymphoproliferative disorders, most often mycosis fungoides and Hodgkin lymphoma.
NCI

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Azotobacter

genus of gram-negative, aerobic bacteria found in soil and water; its organisms occur singly, in pairs or irregular clumps, and sometimes in chains of varying lengths.
CSP

A genus of gram-negative, aerobic bacteria found in soil and water. Its organisms occur singly, in pairs or irregular clumps, and sometimes in chains of varying lengths.
MSH

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náhodné rozdělení

A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
MSH

When referring to an experiment or clinical trial, the process by which animal or human subjects are assigned by chance to separate groups that compare different treatments or other interventions. Randomization gives each participant an equal chance of being assigned to any of the groups.
NCI

The process of assigning trial subjects to treatment or control groups using an element of chance to determine the assignments in order to reduce bias. NOTE: Unequal randomization is used to allocate subjects into groups at a differential rate; for example, three subjects may be assigned to a treatment group for every one assigned to the control group. [ICH E6 1.48] See also balanced study. (CDISC glossary)
NCI

The allocation of individuals to groups by chance, especially in order to control the variables in an experiment.
NCI

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infúzní pumpy implantabilní

Implanted fluid propulsion systems with self-contained power source for providing long-term controlled-rate delivery of drugs such as chemotherapeutic agents or analgesics. Delivery rate may be externally controlled or osmotically or peristatically controlled with the aid of transcutaneous monitoring.
MSH

A small device installed under the skin to administer a steady dose of drugs.
NCI

A small device installed under the skin to provide long-term controlled-rate delivery of drugs such as chemotherapeutic agents or analgesics. Delivery rate may be externally controlled or osmotically or peristaltically controlled with the aid of transcutaneous monitoring.
NCI

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bránice – eventrace

A congenital abnormality characterized by the elevation of the DIAPHRAGM dome. It is the result of a thinned diaphragmatic muscle and injured PHRENIC NERVE, allowing the intra-abdominal viscera to push the diaphragm upward against the LUNG.
MSH

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alternativní sestřih

A process whereby multiple RNA transcripts are generated from a single gene. Alternative splicing involves the splicing together of other possible sets of EXONS during the processing of some, but not all, transcripts of the gene. Thus a particular exon may be connected to any one of several alternative exons to form a mature RNA. The alternative forms of mature MESSENGER RNA produce PROTEIN ISOFORMS in which one part of the isoforms is common while the other parts are different.
MSH

Alternate Splicing is a process in which multiple protein isoforms or products are generated from a single gene as a result of splicing together different nonconsecutive exons during the processing of initially identical nascent transcripts of a gene into mature mRNA transcripts. An exon may be connected to any one of several alternative exons to form the mRNA and generate related proteins, often in a tissue or developmental stage specific manner.
NCI

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baktérie – počet

The quantitative determination of bacterial populations. The two most widely used methods for determining bacterial numbers are: 1) the standard, or viable, plate count method and 2) spectrophotometric (turbidimetric) analysis.
NCI

A measurement of the bacteria in a biological specimen.
NCI

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Raynaudův fenomén

WHAT: Raynaud`s phenomenon.
AIR

A set of symptoms characteristic of peripheral vascular disease, namely caused by an inappropriate response of the peripheral arteries in reaction to environmental stimuli, usually to the cold. The term is used when an underlying disease (mostly connective tissue/autoimmune disorders such as lupus, scleroderma, rheumatoid arthritis, etc.) is primarily causative and a range of symptoms including the peripheral vascular spasm is secondary. The term does not refer to the primary Raynaud`s or Raynaud`s disease.
NCI

Intermittent bilateral attacks of ischemia of the fingers or toes and sometimes of the ears or nose, marked by severe pallor, and often accompanied by paresthesia and pain.
NCI

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inosindifosfát

An inosine nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
MSH

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dichlorfenamid

A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
MSH

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Ambystoma mexicanum

A salamander found in Mexican mountain lakes and accounting for about 30 percent of the urodeles used in research. The axolotl remains in larval form throughout its life, a phenomenon known as neoteny.
MSH

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pobaltské republiky

The collective name for the republics of ESTONIA; LATVIA; and LITHUANIA on the eastern shore of the Baltic Sea. (Webster`s New Geographical Dictionary, 1988, p111)
MSH

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receptory opiátové

Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known.
MSH

family of cell surface receptors which mediate opiate drug effects on neurons, lymphocytes, macrophages, and other cells; may or may not coincide with neuropeptide receptors; some are G protein coupled to calcium channel inhibition.
CSP

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ústavy – řídící týmy

Administrator-selected management groups who are responsible for making decisions pertaining to the provision of integrated direction for various institutional functions.
MSH

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dieta kariogenní

A diet that contributes to the development and advancement of DENTAL CARIES.
MSH

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aminy

A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

group of compounds derived from ammonia by substituting organic radicals for the hydrogens.
CSP

A class of organic compounds that contain nitrogen as the pivotal atom for functional groups. There are several different types of amines and the class is extensive.
NCI

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Basidiomycota

phylum of fungi that produce their sexual spores (basidiospores) on the outside of the basidium; includes forms commonly known as mushrooms, boletes, puffballs, earthstars, stinkhorns, bird`s-nest fungi, jelly fungi, bracket or shelf fungi, and rust and smut fungi.
CSP

A phylum of fungi that produce their sexual spores (basidiospores) on the outside of the basidium. It includes forms commonly known as mushrooms, boletes, puffballs, earthstars, stinkhorns, bird`s-nest fungi, jelly fungi, bracket or shelf fungi, and rust and smut fungi.
MSH

A phylum of filamentous fungi that reproduce sexually via the formation of specialized club-shaped end cells called basidia that normally bear external spores.
NCI

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